Gastroenterology (all articles)
Clinical effects of antivirals for hepatitis C: context is critical
23 Jun, 2017 | 13:56h | UTCEditorial: Clinical effects of antivirals for hepatitis C: context is critical – The Lancet Gastroenterology & Hepatology (free)
Original Cochrane review: Direct-acting antivirals for chronic hepatitis C – Cochrane Library (link to summary – $ for full-text)
Commentary in The Guardian: ‘Miracle’ hepatitis C drugs costing £30k per patient ‘may have no clinical effect’ (free)
Update on anti-TNF agents and other new drugs for IBD
23 Jun, 2017 | 13:27h | UTCClinical Review: Update on anti-tumor necrosis factor agents and other new drugs for inflammatory bowel disease – The BMJ (free)
Aspirin and other NSAIDs and colorectal cancer survival
21 Jun, 2017 | 18:01h | UTCTiming of Aspirin and Other Nonsteroidal Anti-Inflammatory Drug Use Among Patients With Colorectal Cancer in Relation to Tumor Markers and Survival – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: Study Informs NSAID Benefit in Colon Cancer – MedPage Today (free registration required)
Observational data suggests a benefit for individuals with KRAS wild-type tumors
New colorectal cancer screening guidelines
20 Jun, 2017 | 19:51h | UTCCommentaries: Task Force presents new ranking of colorectal cancer screening tests – American Society of Gastrointestinal Endoscopy, via EurekAlert (free) AND Latest Colorectal Cancer Screening Guidelines – Latest Colorectal Cancer Screening Guidelines – GI and Hepatology News (free)
Related: Colorectal Cancer Screening – U.S. Preventive Services Task Force (free)
A Good News Story About Diarrhea
20 Jun, 2017 | 12:21h | UTCA Good News Story About Diarrhea — With One Surprising Exception – NPR Goats and Soda (free)
See the original Global Burden of Disease Study with Diarrheal disease trends and commentaries in our June 5th issue, see #5
Surgeon Variation in Complications With Minimally Invasive and Open Colectomy
20 Jun, 2017 | 12:23h | UTCSurgeon Variation in Complications With Minimally Invasive and Open Colectomy: Results From the Michigan Surgical Quality Collaborative – JAMA Surgery (free) (RT @MaryDixonWoods see Tweet)
Surgeon-level variation in complications among surgeons was nearly twice as great for Minimally Invasive Colectomy than for Open Colectomy, implying a need for improved training in adoption of minimally invasive techniques.
Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer
19 Jun, 2017 | 12:59h | UTCCommentary: New web calculator to more accurately predict bowel cancer survival – University of Nottingham, via EurekAlert (free)
See also: QCancer-2017(colorectal, survival) risk calculator (free risk calculator based on the data)
Guidelines for gastro-entero-pancreatic neuroendocrine neoplasms
19 Jun, 2017 | 12:46h | UTC
Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma
16 Jun, 2017 | 01:35h | UTC
Pancreatic Adenocarcinoma: Improving Prevention and Survivorship
16 Jun, 2017 | 01:33h | UTCPancreatic Adenocarcinoma: Improving Prevention and Survivorship – 2017 ASCO Educational Book (free)
Inflammatory Bowel Disease in Childhood and Adolescence
16 Jun, 2017 | 01:10h | UTCInflammatory Bowel Disease in Childhood and Adolescence – Deutsches Ärzteblatt (free)
Age-specific risks, severity, time course, and outcome of bleeding on long-term antiplatelet treatment after vascular events
15 Jun, 2017 | 00:47h | UTCInvited commentary: Preventing major gastrointestinal bleeding in elderly patients (free)
Commentaries: Aspirin Bleeding Risk in Over 75s Higher Than Thought – Medscape (free registration required) AND Aspirin linked to higher risk of serious bleeding in the elderly – Reuters Health News (free)
In this cohort, the risk of major bleeding increased sharply in patients above 75 years.
Role of endoscopy in primary sclerosing cholangitis
11 Jun, 2017 | 19:45h | UTCCommentary: Endoscopy’s role in primary sclerosing cholangitis: a clinical guideline – Clinical Advisor (free)
Gastroesophageal Reflux Disease Guideline
12 Jun, 2017 | 19:47h | UTC
#ASCO2017 – Risk-Based Approach to Chemotherapy Duration Recommended for Stage III Colon Cancer
7 Jun, 2017 | 15:24h | UTC#ASCO2017 (Unpublished results) – Risk-Based Approach to Chemotherapy Duration Recommended for Stage III Colon Cancer – ASCO Daily News(free) AND ASCO2017:The IDEA Collaboration: Global Study Sets New Risk-Based Standard to Personalize Chemotherapy for Colon Cancer After Surgery – ASCO Post (free)
Commentaries: Chemo Cut in Half Following Surgery Without Increased Recurrence Risk in Patients With Low-Risk Colon Cancer – Targeted Oncology (free) Less Is More: Patients With Colon Cancer Get a Chemo Break – Medscape (free registration required) Cutting Chemo Time in Low-Risk Colon Ca an Option – MedPage Today (free registration required)
Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (again)
7 Jun, 2017 | 15:21h | UTCAntibiotics Versus Surgical Therapy for Uncomplicated Appendicitis: Systematic Review and Meta-analysis of Controlled Trials – Annals of Surgery (link to abstract – $ for full-text)
Commentary: Antibiotics Versus Surgery: Equally Effective in Treating Appendicitis? – Medscape (free registration required)
This meta-analysis and the author’s conclusions do not favor antibiotics alone for the treatment of uncomplicated appendicitis, contradiction the results of other recent meta-analysis, as well as a recent guideline on the subject, suggesting antibiotics might be an option in selected cases.
Inflammatory bowel disease: Five things physicians and patients should question
7 Jun, 2017 | 15:19h | UTC
Association Between Cirrhosis and Stroke
7 Jun, 2017 | 15:18h | UTCAssociation Between Cirrhosis and Stroke in a Nationally Representative Cohort – JAMA Neurology (free)
Commentary: Cirrhosis Tied to Stroke Risk- Physician’s First Watch (free)
Patients with cirrhosis seem to have a higher risk of stroke, particularly hemorrhagic stroke.
Estimates of global, regional, and national morbidity, mortality, and aetiologies of diarrhoeal diseases
5 Jun, 2017 | 14:44h | UTCInvited commentary: Diarrhoeal disease trends in the GBD 2015 study: optimism tempered by skepticism (free)
Other commentaries: Despite substantial global reduction in diarrhea deaths, half a million children still die from diseases each year – Institute for Health Metrics and Evaluation (IHME) (free) AND Global diarrhoea deaths down by a third – BBC News (free)
“Deaths due to diarrhoea in children under 5 down 34% 2005-15, but still 4th leading cause of death” (RT @TheLancetInfDis see Tweet)
“Global diarrhoea deaths in children down by a third, but still fourth biggest killer in under fives, >500,000 a year” (RT @anetrid see Tweet)
Autoimmune gastritis
4 Jun, 2017 | 19:06h | UTCReview: Autoimmune gastritis – Wiener Medizinische Wochenschrift (free)
The diagnosis and management of patients with primary biliary cholangitis
2 Jun, 2017 | 18:42h | UTCCommentary: EASL releases updated guidelines for managing hepatitis B virus infection – Clinical Advisor (free registration required)
Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection
2 Jun, 2017 | 18:40h | UTCSofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: When DAA Treatment for Hepatitis C Fails, 3-Drug Regimen “Highly Effective” – Physician’s First Watch (free)
Chronic constipation: Update on management
2 Jun, 2017 | 18:38h | UTCReview: Chronic constipation: Update on management – Cleveland Clinic Journal of Medicine (free)
Guidelines on the Management of Intra-Abdominal Infection
26 May, 2017 | 15:10h | UTCRelated: Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free)
Reoperation and Medicare Expenditures After Laparoscopic Gastric Band Surgery
23 May, 2017 | 14:25h | UTCReoperation and Medicare Expenditures After Laparoscopic Gastric Band Surgery – JAMA Surgery (link to abstract – $ for full-text)
Commentaries: Following gastric band surgery, device-related reoperation common, costly – Science Daily (free) AND Safety, Effectiveness of Gastric Banding Called Into Question – Medscape (free registration required) AND 1 In 5 Gastric Band Surgeries Require Corrective Operations – American Council on Science and Health (free)