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Gastroenterology (all articles)

[Abstract Only] Randomized Trial: Treatment of Helicobacter Pylori Reduces Gastric Cancer Among Patients with Positive Family History

30 Jan, 2020 | 07:39h | UTC

Family History of Gastric Cancer and Helicobacter pylori Treatment – New England Journal of Medicine (link to abstract – $ for full-text)

Visual Abstract: Family History of Gastric Cancer and Helicobacter pylori Treatment (free)

Commentary: Antibiotic therapy cuts stomach cancer rate by more than half in high-risk population – Reuters (free)

 


ACG Guideline: Small Intestinal Bacterial Overgrowth

29 Jan, 2020 | 08:25h | UTC

ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth – The American Journal of Gastroenterology (free PDF)

 


Viewpoint: Manipulating the Human Microbiome to Manage Disease

29 Jan, 2020 | 08:03h | UTC

Manipulating the Human Microbiome to Manage Disease – JAMA (free for a limited period)

Author Interview: The Potential of Manipulating the Human Microbiome to Manage Disease – JAMA (free)

 


Meta-Analysis: Induction Immunosuppression in Adults Undergoing Liver Transplantation

26 Jan, 2020 | 22:38h | UTC

Induction immunosuppression in adults undergoing liver transplantation: a network meta‐analysis – Cochrane Library (free)

Summary: Medical interventions to prevent early graft rejection after liver transplantation – Cochrane Library (free)

 


Meta-Analysis: Antibiotic Prophylaxis to Prevent Spontaneous Bacterial Peritonitis in People with Liver Cirrhosis

26 Jan, 2020 | 22:37h | UTC

Antibiotic prophylaxis to prevent spontaneous bacterial peritonitis in people with liver cirrhosis: a network meta-analysis – Cochrane Library (free)

Summary: Use of antibiotics to prevent spontaneous bacterial peritonitis in people with advanced liver disease – Cochrane Library (free)

 


Meta-Analysis: Treatment for Ascites in Adults with Decompensated Liver Cirrhosis

26 Jan, 2020 | 22:36h | UTC

Treatment for ascites in adults with decompensated liver cirrhosis: a network meta‐analysis – Cochrane Library (free)

Summary: Treatments for ascites in people with advanced liver disease – Cochrane Library (free)

 


[Abstract Only] Randomized Trial: Primary Needle-Knife Fistulotomy vs. Conventional Cannulation in Patients at High-Risk of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

26 Jan, 2020 | 22:32h | UTC

Primary Needle-Knife Fistulotomy Versus Conventional Cannulation Method in a High-Risk Cohort of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis – The American Journal of Gastroenterology (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


Randomized Trial: Seven-day Vonoprazan and Low-dose Amoxicillin Dual Therapy as First-line Helicobacter Pylori Treatment

24 Jan, 2020 | 07:58h | UTC

Seven-day vonoprazan and low-dose amoxicillin dual therapy as first-line Helicobacter pylori treatment: a multicentre randomised trial in Japan – Gut (free)

Commentary: Dual Therapy for 7 Days Effective for H. Pylori Eradication – Medscape (free registration required)

 


Update on the Diagnosis and Management of Exocrine Pancreatic Insufficiency

24 Jan, 2020 | 07:57h | UTC

Update on the diagnosis and management of exocrine pancreatic insufficiency – F1000Research (free)

 


Randomized Trial: Early Surgery vs. Endoscopy-First Approach on Pain in Patients with Chronic Pancreatitis

23 Jan, 2020 | 09:43h | UTC

Effect of Early Surgery vs Endoscopy-First Approach on Pain in Patients With Chronic Pancreatitis: The ESCAPE Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Tracing the Evidence to Address Painful Chronic Pancreatitis With Surgery (free)

See also: Visual Abstract

 


The Global, Regional, and National Burden of Cirrhosis by Cause in 195 Countries and Territories

23 Jan, 2020 | 09:38h | UTC

The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet Gastroenterology & Hepatology (free)

Invited Commentary: Addressing the global cirrhosis epidemic: one size will not fit all – The Lancet Gastroenterology & Hepatology (free)

Related: Findings from the Global Burden of Disease Study 2017 – The Lancet / Institute for Health Metrics and Evaluation (free PDF)

 

Related Commentary on Twitter

 


[Abstract Only] Randomized Trial: Polypectomy During the Insertion Phase vs. During Withdrawal Phase of Colonoscopy

23 Jan, 2020 | 02:03h | UTC

Clinical importance of cold polypectomy during the insertion phase in the left side of the colon and rectum: a multicenter randomized controlled trial (PRESECT STUDY) – Gastrointestinal Endoscopy (link to abstract – $ for full-text)

 


[Abstract Only] Meta-Analysis: Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics May be Safe

22 Jan, 2020 | 09:31h | UTC

Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum (link to abstract – $ for full-text)

Related: Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis (randomized trials on the subject)

 


Randomized Trial: Efficacy of Glecaprevir and Pibrentasvir in Patients with Chronic HCV Genotype 1 Patients After Treatment Failure with NS5A Inhibitor Plus Sofosbuvir Therapy

22 Jan, 2020 | 09:11h | UTC

Efficacy of Glecaprevir and Pibrentasvir in Patients With Genotype 1 Hepatitis C Virus Infection With Treatment Failure After NS5A Inhibitor Plus Sofosbuvir Therapy – Gastroenterology (free)

Editorial: Retreatment Options for Patients Who Failed Direct-Acting Antiviral Regimens Containing NS5A Inhibitors: Is Glecaprevir/Pibrentasvir a Valid and Robust Option? (free)

Source: EvidenceAlerts

 

Related Commentary on Twitter

 


Screening for Colon Cancer in Older Adults: Risks, Benefits, and When to Stop

21 Jan, 2020 | 03:02h | UTC

Screening for Colon Cancer in Older Adults: Risks, Benefits, and When to Stop – Mayo Clinic Proceedings (free)

 


Update on the Management of Inflammatory Bowel Disease During Pregnancy and Breastfeeding

21 Jan, 2020 | 01:17h | UTC

Update on the Management of Inflammatory Bowel Disease during Pregnancy and Breastfeeding – Digestion (free)

 


Meta-analysis: Stage-Specific Sensitivity of Fecal Immunochemical Tests for Detecting Colorectal Cancer

21 Jan, 2020 | 01:13h | UTC

Stage-Specific Sensitivity of Fecal Immunochemical Tests for Detecting Colorectal Cancer: Systematic Review and Meta-Analysis – American Journal of Gastroenterology (free)

Source: EvidenceAlerts

 


AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis

19 Jan, 2020 | 21:47h | UTC

AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis – Gastroenterology (free PDF)

Related: British Society of Gastroenterology Guidelines on the Management of Inflammatory Bowel Disease (guidelines on the subject)

 


The PEPTIC Randomized Clinical Trial: Similar Outcomes with Stress Ulcer Prophylaxis with Proton Pump Inhibitors vs. Histamine-2 Receptor Blockers Among ICU Patients Receiving Invasive Mechanical Ventilation

19 Jan, 2020 | 21:42h | UTC

Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial – JAMA (free)

Editorial: Proton Pump Inhibitors vs Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis in Critically Ill Patients: Issues of Interpretability in Pragmatic Trials (free for a limited period)

Conference Presentation: Effect of Stress Ulcer Prophylaxis With PPIs vs H2RBs on Mortality in Ventilated ICU Patients (free)

Commentaries: JC: The PEPTIC study PPI vs H2RBs on the ICU – St Emlyn’s (free) AND Risks And Benefits Of Proton Pump Inhibitors To Prevent Gi Bleeds In Intensive Care Patients – MedicalResearch.com (free)

 


An Integrated Perfusion Machine Preserves Injured Human Livers for 1 Week

16 Jan, 2020 | 04:08h | UTC

An integrated perfusion machine preserves injured human livers for 1 week – Nature Biotechnology (free for a limited period)

Commentaries: Machine keeps human livers alive for one week outside of the body – University of Zurich (free) AND Machine Could Expand Pool of Livers for Donation – HealthDay News (free)

 


[Abstract Only] Cohort Study: Colorectal Cancer in Ulcerative Colitis

16 Jan, 2020 | 02:34h | UTC

Colorectal cancer in ulcerative colitis: a Scandinavian population-based cohort study – The Lancet (link to abstract – $ for full-text)

Commentary: Association Between Colorectal Cancer and Ulcerative Colitis – The ASCO Post (free)

 


Expert Statement: Clostridioides Difficile Infection in the Critically Ill

15 Jan, 2020 | 08:11h | UTC

Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free for a limited period)

Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject)

 


Review: Work Up of Fatty Liver by Primary Care Physicians

14 Jan, 2020 | 00:36h | UTC

Work Up of Fatty Liver by Primary Care Physicians, Review – Annals of Medicine and Surgery (free)

 


Guideline on the Management of Bile Acid Diarrhea

14 Jan, 2020 | 00:25h | UTC

Canadian Association of Gastroenterology Clinical Practice Guideline on the Management of Bile Acid Diarrhea – Clinical Gastroenterology and Hepatology (free)

 


AGA Clinical Practice Update: Management of Pancreatic Necrosis

9 Jan, 2020 | 01:27h | UTC

American Gastroenterological Association Clinical Practice Update: Management of Pancreatic Necrosis – Gastroenterology (free)

Related Reviews: Step-up approach for the management of pancreatic necrosis: a review of the literature – Trauma Surgery & Acute Care Open (free) AND Management of severe acute pancreatitis – The BMJ (free for a limited period)

Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)

 


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