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Gastroenterology (all articles)

[Abstract Only] Observational Study: Use of Low-dose Aspirin Linked to Lower Risk of Hepatocellular Carcinoma and Liver-related Mortality

12 Mar, 2020 | 08:19h | UTC

Association of Aspirin with Hepatocellular Carcinoma and Liver-Related Mortality – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Aspirin Use Associated with Reduced Hepatocellular Carcinoma and Liver-Related Mortality – NEJM Journal Watch (free)

 


Clinical Update: Diagnosis and Treatment of Clostridioides (Clostridium) difficile Infection in Adults in 2020

10 Mar, 2020 | 08:32h | UTC

Diagnosis and Treatment of Clostridioides (Clostridium) Difficile Infection in Adults in 2020 – JAMA (free for a limited period)

Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject) AND Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free)

 


Albumin in Decompensated Cirrhosis: New Concepts and Perspectives

8 Mar, 2020 | 20:23h | UTC

Albumin in decompensated cirrhosis: new concepts and perspectives – Gut (free)

 


Study: Colorectal Cancer Burden Shifting to Younger Individuals

6 Mar, 2020 | 10:15h | UTC

News Release: Colorectal Cancer Burden Shifting to Younger Individuals – American Cancer Society (free)

Original Report: Colorectal cancer statistics, 2020 – CA: A Cancer Journal for Clinicians (free)

Commentary: Half of new colon and rectal cancer diagnoses are now in people age 66 and younger, report finds – CNN (free)

 


Short Review: Time‐Sensitive Interventions in Hospitalized Patients with Cirrhosis

4 Mar, 2020 | 08:24h | UTC

Time‐Sensitive Interventions in Hospitalized Patients with Cirrhosis – Clinical Liver Disease (free)

 


USPSTF Statement: Screening for Hepatitis C Virus Infection in Adolescents and Adults

3 Mar, 2020 | 08:03h | UTC

Recommendation Statement: Screening for Hepatitis C Virus Infection in Adolescents and Adults: US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Screening for Hepatitis C Virus Infection in Adolescents and Adults (free audio)

Editorials: Universal Screening for Hepatitis C Virus Infection: A Step Toward Elimination – JAMA (free for a limited period) AND USPSTF’s Hepatitis C Screening Recommendation—A Necessary Step to Tackling an Evolving Epidemic – JAMA Network Open (free)

Evidence Report and Systematic Review: Screening for Hepatitis C Virus Infection in Adolescents and Adults – US Preventive Services Task Force (free)

JAMA Patient Page: Screening for Hepatitis C Virus Infection (free)

Commentary: Experts recommend testing U.S. adults ages 18-79 for hep C – Reuters (free)

 


Adult Liver Transplantation: A UK Clinical Guideline

1 Mar, 2020 | 19:33h | UTC

Adult liver transplantation: A UK clinical guideline – part 1: pre-operation – Frontline Gastroenterology (free)

Adult liver transplantation: UK clinical guideline – part 2: surgery and post-operation – Frontline Gastroenterology (free)

 


[Abstract Only] Study: Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

28 Feb, 2020 | 08:18h | UTC

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Higher Microbiota Diversity in Hematologic Cancer Treatment Could Lower Mortality Risk, Study Finds – AJMC (free) AND Gut Diversity Before HCT Predicts Survival in Blood Cancers – MedPage Today (free registration required)

 


Perspective: The Low-FODMAP Diet Helps IBS Symptoms, but Questions Remain

27 Feb, 2020 | 08:33h | UTC

The Low-FODMAP Diet Helps IBS Symptoms, but Questions Remain – JAMA (free for a limited period)

Related: Low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet improves symptoms in adults suffering from irritable bowel syndrome (IBS) compared to standard IBS diet: A meta-analysis of clinical studies – PLOS One (free) AND The Low FODMAP Diet: Recent Advances in Understanding Its Mechanisms and Efficacy in IBS – Gut (free PDF)

 


Consensus Recommendations: Follow-Up After Colonoscopy and Polypectomy

26 Feb, 2020 | 07:14h | UTC

Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology (free link via Google Scholar)

Summary: Updated Polypectomy Surveillance Recommendations – NEJM Journal Watch (free)

Related: British Society of Gastroenterology/Association of Coloproctology of Great Britain and Ireland/Public Health England post-polypectomy and post-colorectal cancer resection surveillance guidelines – Gut (free guidelines and studies on the subject)

 


EASL Clinical Practice Guideline: Occupational Liver Diseases

25 Feb, 2020 | 06:47h | UTC

EASL Clinical Practice Guideline: Occupational liver diseases – Journal of Hepatology (free)

 


Meta-Analysis: Evaluation of the Association Between Gastric Acid Suppression and Risk of Intestinal Colonization with Multidrug-Resistant Microorganisms

25 Feb, 2020 | 06:39h | UTC

Evaluation of the Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With Multidrug-Resistant Microorganisms: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free)

Author Interview: Evaluation of Association Between Gastric Acid Suppression and Risk of Intestinal Colonization With MDROs – JAMA (free)

Commentary: Deprescribing Proton Pump Inhibitors: Overcoming Resistance – JAMA Internal Medicine (free for a limited period)

Related: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)

 

Related Commentary on Twitter

 


Review: NAFLD as a Driver of Chronic Kidney Disease

25 Feb, 2020 | 06:05h | UTC

NAFLD as a driver of chronic kidney disease – Journal of Hepatology (free)

 


Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

20 Feb, 2020 | 10:40h | UTC

Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)

Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)

Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)

 


Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU

16 Feb, 2020 | 21:42h | UTC

Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations – Critical Care Medicine (free)

News Release: New guidelines for hepatic failure in the intensive care unit – Wolters Kluwer Health (free)

See also: Executive Summary (free)

 


[Abstract Only] Meta-Analysis: Fecal Occult Blood Testing Should Not be Used as a Diagnostic Tool for Clinical Indications

16 Feb, 2020 | 21:31h | UTC

Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis – The American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: Fecal Occult Blood Tests Should Not Be Used for Diagnostic Indications – NEJM Journal Watch (free for a limited period)

 


Position Statement: Role of Gastrointestinal Endoscopy in the Screening of Digestive Tract Cancers

16 Feb, 2020 | 21:07h | UTC

Role of gastrointestinal endoscopy in the screening of digestive tract cancers in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement – Endoscopy (free)

 


Application of Artificial Intelligence to Gastroenterology and Hepatology

16 Feb, 2020 | 20:38h | UTC

Application of Artificial Intelligence to Gastroenterology and Hepatology – Gastroenterology (free)

 


Non-neoplastic Hepatopancreatobiliary Lesions Simulating Malignancy: Can we Differentiate?

11 Feb, 2020 | 01:50h | UTC

Non-neoplastic hepatopancreatobiliary lesions simulating malignancy: can we differentiate? – Insights into Imaging (free)

 


Study: Lower GI-bleeding in Anticoagulated Patients with Atrial Fibrillation Should Always Raise Suspicion of Colorectal Cancer

9 Feb, 2020 | 20:47h | UTC

Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation – European Heart Journal (free)

Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)

 


ACG Clinical Guideline: Chronic Pancreatitis

6 Feb, 2020 | 02:13h | UTC

ACG Clinical Guideline: Chronic Pancreatitis – American Journal of Gastroenterology (free PDF)

 


Study: Incidence of Early-Onset Colorectal Cancer Underestimated

5 Feb, 2020 | 08:14h | UTC

Trends in Incidence of Early-Onset Colorectal Cancer in the United States Among Those Approaching Screening Age – JAMA Network Open (free)

Commentaries: Study shows advanced colorectal cancers at recommended screening age – Louisiana State University Health Sciences Center (free) AND Should Colon Cancer Screening Begin Before 50? – MedicalResearch.com (free)

Related: Another Study Points to Increased Colorectal Cancer Incidence in Young Adults (studies on the subject)

 


Study Commentary: PEPTIC

2 Feb, 2020 | 19:47h | UTC

PEPTIC – The Bottom Line (free)

Original Study: Effect of Stress Ulcer Prophylaxis With Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial – JAMA (link to abstract, commentaries and study presentation)

 


FDA Safety Communication: Untreated Constipation caused by Clozapine Can Lead to Serious Bowel Problems

31 Jan, 2020 | 01:09h | UTC

FDA strengthens warning that untreated constipation caused by schizophrenia medicine clozapine (Clozaril) can lead to serious bowel problems – U.S. Food & Drug Administration (free)

See also: Clozaril, Fazaclo ODT, Versacloz (clozapine): Drug Safety Communication – FDA Strengthens Warning That Untreated Constipation Can Lead to Serious Bowel Problems – U.S. Food & Drug Administration (free)

Source: FDA Strengthens Constipation Warning on Clozapine – NEJM Journal Watch (free)

 


Systematic Review: Oral Janus Kinase Inhibitors for Maintenance of Remission in Ulcerative Colitis

31 Jan, 2020 | 00:44h | UTC

Oral Janus kinase inhibitors for maintenance of remission in ulcerative colitis – Cochrane Library (free)

Summary: Oral Janus kinase inhibitors (tofacitinib) for maintenance of remission in ulcerative colitis – Cochrane Library (free)

 


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