Gastroenterology (all articles)
Review | Liver transplantation in alcohol-related liver disease and alcohol-related hepatitis.
6 Jul, 2022 | 11:22h | UTCIndeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.
5 Jul, 2022 | 12:09h | UTCRelated:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Review | Preoperative evaluation and management of patients with select chronic gastrointestinal, liver, and renal diseases.
5 Jul, 2022 | 12:16h | UTCRelated:
Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Preoperative Management of Surgical Patients Using Dietary Supplements – Mayo Clinic Proceedings
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
Preoperative Cardiac Risk Assessment – Mayo Clinic Proceedings
Preoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings
The multicenter cancer of pancreas screening study: impact on stage and survival.
5 Jul, 2022 | 11:46h | UTC
Commentary on Twitter
👀 The Cancer of Pancreas Screening (CAPS) program achieves early #PancreaticCancer detection and long-term survival with surveillance ➡️ https://t.co/flqUtSvkcg #JCO #pancSM @mggoggins pic.twitter.com/wj6DMXclVC
— Journal of Clinical Oncology (@JCO_ASCO) June 30, 2022
Review | Artificial intelligence in hepatology – ready for the primetime.
5 Jul, 2022 | 11:30h | UTCBrief Review | Sudden onset hepatitis in children.
4 Jul, 2022 | 12:41h | UTCSudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Related: WHO Updated Report: Severe acute hepatitis of unknown etiology in children. (several articles on the subject)
Commentary on Twitter
NEW! In this COMMENT by @ZaniaStamataki & @kellyda60 summarise what we know so far about sudden onset #hepatitis of unexplained origin in childrenhttps://t.co/AYTR8wrG3C
Read-only link https://t.co/dgyzRhpODT#paediatrics pic.twitter.com/1WLQfaRrdx
— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) July 1, 2022
Systematic Review: Certolizumab pegol for maintenance of medically induced remission in Crohn’s disease.
1 Jul, 2022 | 11:22h | UTCSummary: Certolizumab pegol for the treatment of maintaining inactive Crohn’s disease – Cochrane Library
RCT: FODMAP diet vs. medication in primary care patients with irritable bowel syndrome.
1 Jul, 2022 | 10:46h | UTCDiet or medication in primary care patients with IBS: the DOMINO study – a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute – Gut (link to abstract – $ for full-text)
ESPGHAN position paper on management and follow-up of children and adolescents with coeliac disease.
29 Jun, 2022 | 11:32h | UTC
Network meta-analysis: Dipeptidyl peptidase-4 inhibitors increase the risk of cholecystitis in patients with type 2 diabetes.
29 Jun, 2022 | 11:24h | UTC
WHO Updated Report: Severe acute hepatitis of unknown etiology in children.
28 Jun, 2022 | 11:23h | UTCSevere acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Related:
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
RCT: Diagnostic imaging vs. observation in early equivocal appendicitis.
28 Jun, 2022 | 10:46h | UTC
Systematic Review: Antibiotics for uncomplicated diverticulitis.
27 Jun, 2022 | 11:56h | UTCAntibiotics for uncomplicated diverticulitis – Cochrane Library
Summary: Antibiotics for uncomplicated diverticulitis – Cochrane Library
Related:
Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Elective surgical management of diverticulitis – Current Problems in Surgery
Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Commentary on Twitter
The benefits of antibiotics in diverticulitis are uncertain with respect to complications, emergency✂️, recurrence, elective colonic resections&long‐term complications. This may be because diverticulitis is❌an infectious disorder, but an inflammatory onehttps://t.co/0HmAllw5Af
— John Damianos, M.D. (@john_damianosMD) June 26, 2022
Phase 2 single-arm study: Fazirsiran for liver disease associated with Alpha1-Antitrypsin deficiency.
27 Jun, 2022 | 11:19h | UTCFazirsiran for Liver Disease Associated with Alpha1-Antitrypsin Deficiency – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this small trial in adults with ATT deficiency, fazirsiran was associated with a strong reduction of mutant AAT levels in the serum and liver and concurrent improvements in liver enzyme levels. #ILC2022 https://t.co/RibsKzOQfO pic.twitter.com/BnMcSyfVcq
— NEJM (@NEJM) June 25, 2022
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019.
27 Jun, 2022 | 11:17h | UTCCommentary: Chronic Hepatitis B Infections Decreasing in Recent Years – HCP Live
Commentary on Twitter
New research from #GBDStudy – Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019https://t.co/e0oxlT2gKd#hepB #HBV #nohep #livertwitter @IHME_UW pic.twitter.com/V8h1LrCoUQ
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 21, 2022
M-A: Relationship between serum lipid level and colorectal cancer.
27 Jun, 2022 | 11:01h | UTC
ESPGHAN Position Paper: use of low-FODMAP diet in pediatric gastroenterology.
24 Jun, 2022 | 11:15h | UTC
Dysplastic recurrence after successful treatment for early Barrett’s neoplasia: development and validation of a prediction model.
24 Jun, 2022 | 11:07h | UTC
Consensus report on anatomy, pathophysiology and clinical significance of the gastro-esophageal junction.
23 Jun, 2022 | 10:26h | UTC
AGA Guidelines on the pharmacological management of irritable bowel syndrome.
23 Jun, 2022 | 10:24h | UTCPart 1: Patients with diarrhea: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Diarrhea – Gastroenterology
Part 2: Patients with constipation: AGA Clinical Practice Guideline on the Pharmacological Management of Irritable Bowel Syndrome With Constipation – Gastroenterology
Commentary: AGA issues guidance on drug treatment for patients with IBS – ACP Gastroenterology
Commentary on Twitter
Clinical decision support tool from the @AmerGastroAssn for #IBS based on the most recent evidence.
💩IBS-C: https://t.co/OeswowXhIP
💩IBS-D: https://t.co/4W8PbpV4b0
🔦Spotlight on IBS treatment: https://t.co/oxZfD3m8u5#MedTwitter #GITwitter #DGBI #FGID #motility pic.twitter.com/eiMqCdS8js
— John Damianos, M.D. (@john_damianosMD) June 22, 2022
RCTs: Risankizumab as induction therapy for Crohn’s disease.
23 Jun, 2022 | 10:02h | UTCRisankizumab as induction therapy for Crohn’s disease: results from the phase 3 ADVANCE and MOTIVATE induction trials – The Lancet (link to abstract – $ for full-text)
Related: Risankizumab as maintenance therapy for moderately to severely active Crohn’s disease: results from the multicentre, randomised, double-blind, placebo-controlled, withdrawal phase 3 FORTIFY maintenance trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
In patients with moderately to severely active Crohn's disease, risankizumab was effective and well tolerated as induction therapy, studies indicate.
Find out more: https://t.co/zg70L8RYka #crohnsdisease pic.twitter.com/9evGJAH8ke
— The Lancet (@TheLancet) June 1, 2022
Guideline review: EASL clinical practice guidelines: drug-induced liver injury.
22 Jun, 2022 | 11:27h | UTCOriginal Article: EASL Clinical Practice Guidelines: Drug-induced liver injury – Journal of Hepatology
RCT: Multispecies probiotic for the prevention of antibiotic-associated diarrhea in children.
22 Jun, 2022 | 11:12h | UTCMultispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Commentary: Mixed Results With Probiotic for Kids’ Antibiotic-Related Diarrhea— Randomized trial misses strictly defined endpoint, but researchers point to benefit – MedPage Today (free registration required)
Commentary on Twitter
Study found administration of a multispecies #probiotic to children had no significant effect on the risk of antibiotic-associated diarrhea caused by #Cdifficile or of unknown etiology, but reduced the overall risk of diarrhea regardless of the etiology. https://t.co/Mdq3tl8csb
— JAMA Pediatrics (@JAMAPediatrics) June 21, 2022
Cohort Study: Association of gamma-glutamyltransferase levels with total mortality, liver-related and cardiovascular outcomes.
20 Jun, 2022 | 10:36h | UTC
Commentary on Twitter
Still remember working on this in 2019 but it's out today!
Gamma-GT level has a strong association with mortality outcomes and could add to the prediction of CV mortality
https://t.co/0lzqGfgiGc pic.twitter.com/C8tSZLWlI2— Fred Ho (@fredho42) May 13, 2022
Under a CC BY-NC-ND 4.0 license
RCT: Immune enhancement with Thymosin alpha 1 does not improve outcomes in patients with predicted severe acute necrotizing pancreatitis.
20 Jun, 2022 | 01:11h | UTCImmune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial – Intensive Care Medicine (if the link is paywalled, try this one)