Family Medicine

M-A | Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2.

12 Jul, 2022 | 12:50h | UTC

Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2: An updated systematic review and meta-analysis with meta-regression analyzing influencing factors – PLOS Medicine

Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ

Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection – Cochrane Library

Navigating a Complicated World | Commentary of the new AHA/ACC Chest Pain Guidelines.

12 Jul, 2022 | 12:40h | UTC

Navigating a Complicated World: The American Heart Association/American College of Cardiology/American College of Chest Physicians/Society of Academic Emergency Medicine/Society of Cardiovascular Computed Tomography/Society of Cardiovascular Magnetic Resonance Chest Pain Guidelines – CHEST

Original Guideline: 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD

M-A | Factors correlated with physical function 1 year after total knee arthroplasty in patients with knee osteoarthritis.

12 Jul, 2022 | 12:24h | UTC

Commentary on Twitter

This meta-analysis of 20 prospective cohort studies (11,317 patients) found associations between presurgical BMI, physical function, and osteoarthritis severity and physical function after total knee arthroplasty (TKA). https://t.co/tQf7HytTEW

— JAMA Network Open (@JAMANetworkOpen) July 11, 2022

European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.

11 Jul, 2022 | 12:41h | UTC

European Medicines Agency Recommends Second COVID Booster for People Over 60 – as WHO Ponders Guidance – Health Policy Watch

M-A | Little benefit from viscosupplementation in knee osteoarthritis.

11 Jul, 2022 | 12:39h | UTC

Viscosupplementation for knee osteoarthritis: systematic review and meta-analysis – The BMJ

News Release: Scant evidence to recommend use of hyaluronic acid injections for knee osteoarthritis – BMJ Newsroom

Commentary: Common injections don’t help knee osteoarthritis more than placebo, large data review finds – STAT

Commentary on Twitter

New research finds that injections of hyaluronic acid to treat knee osteoarthritis make almost no difference to pain and might raise risk of adverse events https://t.co/G80BHoOgl3

— The BMJ (@bmj_latest) July 7, 2022

Cohort Study | Adding salt to foods and hazard of premature mortality.

11 Jul, 2022 | 12:35h | UTC

Adding salt to foods and hazard of premature mortality – European Heart Journal (free for a limited period)

Editorial: Salt: the sweet spot?

How contagious is monkeypox — and should you get a vaccine? Here’s the latest.

11 Jul, 2022 | 12:31h | UTC

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

Study shows socioeconomic deprivation is an important, largely unrecognized risk factor for cardiovascular disease.

11 Jul, 2022 | 12:19h | UTC

Socioeconomic Deprivation: An Important, Largely Unrecognized Risk Factor in Primary Prevention of Cardiovascular Disease – Circulation

Systematic Review | Medical methods for first trimester abortion.

11 Jul, 2022 | 12:18h | UTC

Medical methods for first trimester abortion – Cochrane Library

Summary: Are medical methods for early termination of pregnancy effective and do they cause unwanted effects? – Cochrane Library

RCT | Acupuncture for patients with chronic tension-type headache.

11 Jul, 2022 | 12:12h | UTC

Acupuncture for Patients With Chronic Tension-Type Headache: A Randomized Controlled Trial – Neurology (link to abstract – $ for full-text)

News Release: Can acupuncture reduce headaches? – American Academy of Neurology

Commentary:

New Evidence on the Efficacy of Acupuncture for Chronic Tension-type Headache – NeurologyToday

An ancient practice may offer relief from chronic tension headaches – CNN

Review | Anorexia nervosa and the gastrointestinal tract.

11 Jul, 2022 | 12:08h | UTC

Anorexia nervosa and the gastrointestinal tract – Frontline Gastroenterology (free for a limited period)

Commentaries on Twitter

Summary of GI manifestations of anorexia nervosa #FGDebate https://t.co/hwsqfBBrr9 @GastroNW pic.twitter.com/Mp1IHfpGKc

— Frontline Gastro (@FrontGastro_BMJ) October 13, 2021

Table summary of GI manifestations in anorexia nervosa, including rare symptoms #FGDebate @GastroNW https://t.co/hwsqfBBrr9 pic.twitter.com/Thqj1xKLEj

— Frontline Gastro (@FrontGastro_BMJ) October 13, 2021

Study finds childhood obesity occurring at greater frequency, with more severity and at younger ages.

11 Jul, 2022 | 12:10h | UTC

News Release: Study finds childhood obesity occurring at greater frequency, with more severity and at younger ages – Emory University

Original Study: Changes in the Incidence of Childhood Obesity – Pediatrics

M-A | There is no convincing evidence supporting the use of vaginal progesterone in singleton gestations with a history of spontaneous preterm birth.

11 Jul, 2022 | 11:58h | UTC

Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? Evidence from a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

News Release: Progress toward personalized prevention of preterm birth: When progesterone works and when it does not – Wayne State University School of Medicine

A Randomized Trial of Progesterone in Women with Recurrent Miscarriages – New England Journal of Medicine

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy – New England Journal of Medicine

Early vaginal progesterone versus Placebo in Twin Pregnancies for prevention of spontaneous preterm birth (EVENTS): A randomised double-blind trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentary on Twitter

AJOG Systematic Review: Does vaginal progesterone prevent recurrent preterm birth in women with a singleton gestation and a history of spontaneous preterm birth? – Effect of vaginal progesterone on preterm birth <37 weeks of gestation https://t.co/fsPlSZCnsr pic.twitter.com/2z6g3CFgX4

— AJOG (@AJOG_thegray) April 25, 2022

BSG guidelines on the management of functional dyspepsia.

8 Jul, 2022 | 12:03h | UTC

British Society of Gastroenterology guidelines on the management of functional dyspepsia – Gut

Evidence-based clinical practice guidelines for functional dyspepsia 2021 – Journal of Gastroenterology

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia – UEG Journal

M-A | Associations of thiazide use with skin cancers.

8 Jul, 2022 | 11:55h | UTC

Associations of thiazide use with skin cancers: a systematic review and meta-analysis – BMC Medicine

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Association of Hydrochlorothiazide Use and Risk of Malignant Melanoma – JAMA Internal Medicine

Hydrochlorothiazide use and risk of nonmelanoma skin cancer: A nationwide case-control study from Denmark – Journal of the American Academy of Dermatology

RCT | Effect of electroacupuncture on insomnia in patients with depression.

8 Jul, 2022 | 11:45h | UTC

Effect of Electroacupuncture on Insomnia in Patients With Depression: A Randomized Clinical Trial – JAMA Network Open

Invited Commentary: Effects of Electroacupuncture for Depression-Related Insomnia – JAMA Network Open

Commentary on Twitter

This randomized clinical trial found that an 8-weeek electroacupuncture with standard care improved sleep quality for patients with insomnia and depression, compared with sham acupuncture and/or standard care. https://t.co/nacnxEI4Ik

— JAMA Network Open (@JAMANetworkOpen) July 7, 2022

M-A | Antithyroid drug therapy in pregnancy and risk of congenital anomalies.

8 Jul, 2022 | 11:36h | UTC

Antithyroid drug therapy in pregnancy and risk of congenital anomalies: Systematic review and meta-analysis – Clinical Endocrinology

M-A | Prenatal antibiotic exposure, asthma, and the atopic march.

8 Jul, 2022 | 11:31h | UTC

Prenatal antibiotic exposure, asthma, and the atopic march: A systematic review and meta-analysis – Allergy

Egg and dietary cholesterol intake and risk of all-cause, cardiovascular, and cancer mortality: a systematic review and dose-response meta-analysis of prospective cohort studies.

8 Jul, 2022 | 11:23h | UTC

Egg and Dietary Cholesterol Intake and Risk of All-Cause, Cardiovascular, and Cancer Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies – Frontiers in Nutrition

Review | Sickle cell disease.

7 Jul, 2022 | 12:59h | UTC

Sickle Cell Disease: A Review – JAMA (free for a limited period)

Audio Clinical Review: Sickle Cell Disease – JAMA

Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.

7 Jul, 2022 | 13:00h | UTC

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

M-A | It is not safe to withhold antibiotic use in uncomplicated urinary tract infections in adult women.

7 Jul, 2022 | 12:47h | UTC

Reducing antibiotic use in uncomplicated urinary tract infections in adult women: a systematic review and individual participant data meta-analysis – Clinical Microbiology and Infection

Commentary on Twitter (thread – click for more)

A really important analysis of previous trials!

1/ All short-term outcomes were worse for women given non-antibiotic strategies, including need for future antibiotics (number needed to harm=5!) https://t.co/iozelljFLk

— Annie Joseph (@ajosephnotts) July 2, 2022