Family Medicine
Podcast | Meningitis pearls.
12 Aug, 2022 | 14:25h | UTC#346 Meningitis – The Curbsiders
Podcast | Vitamin and mineral supplementation: a USPSTF update.
12 Aug, 2022 | 14:23h | UTC#345 Vitamin and Mineral supplementation: A USPSTF Update with Dr. Michael Barry – The Curbsiders
Podcast | Multiple Sclerosis pearls for the general practitioner.
12 Aug, 2022 | 14:21h | UTC#344 Multiple Sclerosis with Dr. Annette Okai – The Curbsiders
RCT | Removal of small, asymptomatic kidney stones and incidence of relapse.
11 Aug, 2022 | 12:23h | UTCRemoval of Small, Asymptomatic Kidney Stones and Incidence of Relapse – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Removal of small, asymptomatic kidney stones during surgery to remove ureteral or contralateral stones resulted in less relapse than nonremoval and in similar numbers of subsequent emergency department visits. https://t.co/MRgFUnF1C0 pic.twitter.com/19ahPuHyNS
— NEJM (@NEJM) August 10, 2022
Cohort Study | Risk of hip fracture in meat-eaters, pescatarians, and vegetarians.
11 Aug, 2022 | 12:11h | UTCNews Release: Vegetarian women are at a higher risk of hip fracture – University of Leeds
Systematic Review | Replacing salt with low‐sodium salt substitutes for cardiovascular health in adults, children and pregnant women.
10 Aug, 2022 | 15:38h | UTCRelated:
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
M-A | Effects of salt substitutes on clinical outcomes.
10 Aug, 2022 | 15:40h | UTCEffects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart
Commentary: Swapping salt for substitutes reduces risk of stroke and heart conditions – study – The Guardian
Related:
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary from the author on Twitter
Our latest meta-analysis shows consistent effects of salt substitutes on BP across diverse geographies and populations. Protective effects on clinical outcomes are likely to be generalizable to countries worldwide. https://t.co/C273yK6Bek
— Xuejun Yin (@XuejunYin) August 10, 2022
Viewpoint | Making electronic health records both SAFER and SMARTER.
10 Aug, 2022 | 15:28h | UTCMaking Electronic Health Records Both SAFER and SMARTER – JAMA (free for a limited period)
Author Interview: Making Electronic Health Records More Supportive for Clinicians – JAMA
Commentary: Opinion: physicians need to use smarter, safer EHRS – healthleaders
Related:
The EMR has changed the doctor-patient duet into a ménage-à-trois – STAT
The future of electronic health records – Nature
Cohort Study | Association of younger vs. older ages with changes in incidence of stroke and other vascular events, 2002-2018.
10 Aug, 2022 | 15:30h | UTCAssociation of Younger vs Older Ages With Changes in Incidence of Stroke and Other Vascular Events, 2002-2018 – JAMA (free for a limited period)
See also: Diverging Temporal Trends in Stroke Incidence in Younger vs Older People: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Commentaries on Twitter
Data from Oxford area in @JAMA_current show worrisome incr. in stroke rate in adults <55 yrs comparing two time periods. 67% incr seen in younger adults, 15% decr in older adults. Need further study of why young stroke rates are on the rise#MYStrokeCenterhttps://t.co/MG4MgUGAA4
— Seemant Chaturvedi (@ChaturvediNeuro) August 9, 2022
The consistently divergent temporal trend in stroke incidence at younger vs older ages highlights the urgent need to better understand etiology and prevention of stroke at younger ages. https://t.co/phhRcpWwRw
— JAMA Neurology (@JAMANeuro) August 9, 2022
RCT | Effectiveness of early time-restricted eating for weight loss, fat loss, and cardiometabolic health in adults with obesity.
9 Aug, 2022 | 12:59h | UTCAuthor Interview: Effectiveness of Early Time-Restricted Eating for Weight Loss and Fat Loss in Adults With Obesity – JAMA
Commentaries:
Time-Restricted Eating to Improve Health—A Promising Idea in Need of Stronger Clinical Trial Evidence – JAMA Internal Medicine (free for a limited period)
Related:
Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition
Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link to abstract – $ for full-text)
M-A | Global prevalence and incidence of tinnitus.
9 Aug, 2022 | 12:57h | UTCGlobal Prevalence and Incidence of Tinnitus: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Commentary: Review: Global Pooled Prevalence of Tinnitus 14.4 Percent – HealthDay
Commentary on Twitter
The global burden of #tinnitus is large, similar to #migraine and pain, and the lack of effective treatment options justifies a major investment in research in this area. https://t.co/9uVJmnYh9c
— JAMA Neurology (@JAMANeuro) August 8, 2022
Guideline Synopsis | Treatment of Clostridioides difficile infection.
9 Aug, 2022 | 12:54h | UTCTreatment of Clostridioides difficile Infection – JAMA (free for a limited period)
Original Guideline: ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections – American Journal of Gastroenterology
Related Guidelines:
Commentary on Twitter
A summary of @AmCollegeGastro’s 2021 guidelines on treatment of Clostridioides difficile infection. https://t.co/QzrMa71ttu
— JAMA (@JAMA_current) August 8, 2022
Diagnostic Test Interpretation | Serum Cystatin C for estimation of glomerular filtration rate.
9 Aug, 2022 | 12:52h | UTCSerum Cystatin C for Estimation of GFR – JAMA (free for a limited period)
Commentary on Twitter
An 80-year-old man with #type2diabetes and #hypertension was referred to the nephrology clinic for assessment of persistent hyperkalemia despite discontinuation of his ACE inhibitor. #JAMADiagnosticTestInterpretation https://t.co/kxg0yHeGUr
— JAMA (@JAMA_current) August 8, 2022
RCT | Effect of a comprehensive telehealth intervention vs. telemonitoring and care coordination in patients with persistently poor type 2 diabetes control.
9 Aug, 2022 | 12:44h | UTCEffect of a Comprehensive Telehealth Intervention vs Telemonitoring and Care Coordination in Patients With Persistently Poor Type 2 Diabetes Control: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A comprehensive telehealth intervention improved HbA1c in persistently poorly-controlled type 2 diabetes compared to a simpler telehealth intervention; the comprehensive telehealth approach may warrant implementation in systems with appropriate resources. https://t.co/qXnuclyipQ
— JAMA Internal Medicine (@JAMAInternalMed) July 29, 2022
Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.
9 Aug, 2022 | 12:42h | UTCSmoking cessation for secondary prevention of cardiovascular disease – Cochrane Library
RCT | Effectiveness of Varenicline and Cytisine for alcohol use reduction among people with HIV and substance use.
9 Aug, 2022 | 12:35h | UTC
Commentary on Twitter
In this RCT, varenicline and cytisine were not more efficacious than nicotine to treat risky drinking and smoking among individuals with HIV; rates of behavior change for alcohol consumption and smoking were high in all treatment groups. #OrigInvestigation https://t.co/h8M6e5nOkf
— JAMA Network Open (@JAMANetworkOpen) August 5, 2022
ACG Clinical Guideline | Gastroparesis.
8 Aug, 2022 | 12:00h | UTCACG Clinical Guideline: Gastroparesis – The American Journal of Gastroenterology
RCT | Effect of once-weekly semaglutide versus thrice-daily insulin aspart, both as add-on to metformin and optimized insulin glargine treatment in participants with type 2 diabetes.
8 Aug, 2022 | 11:56h | UTC
Cochrane Collection | Achieving sustainable healthcare through deprescribing of unnecessary medications: making sense of the evidence.
8 Aug, 2022 | 11:50h | UTC
Systematic Review | Impact of low‐dose computed tomography screening on lung cancer‐related mortality.
8 Aug, 2022 | 11:52h | UTCSummary: Impact of computed tomography (CT) on lung cancer screening – Cochrane Library
Related:
Screening for Lung Cancer: CHEST Guideline and Expert Panel Report.
Is the contemporary care of older persons with acute coronary syndrome evidence-based?
8 Aug, 2022 | 11:48h | UTC
Commentary from the author on Twitter
♦️Heart disease leading cause of death in older adults
♦️Less likely to receive guideline recommended treatment
♦️Frailty, multi-morbidity linked to worse outcomes
♦️We explore this in our manuscript led by @GregBMills1
💥Open access for free download😊https://t.co/l452O1QJTJ pic.twitter.com/HCRuwle3KK— Professor Vijay Kunadian (@VijayKunadian) January 29, 2022
Retrospective Cohort Study | Retrospective evaluation of ophthalmological and neurological outcomes for infants born before 24 weeks gestational age.
8 Aug, 2022 | 11:24h | UTC
Heavy periods: evidence to help you weigh up treatment options.
5 Aug, 2022 | 14:40h | UTCHeavy periods: evidence to help you weigh up treatment options – Evidently Cochrane
Original Article: Interventions for heavy menstrual bleeding; overview of Cochrane reviews and network meta‐analysis – Cochrane Library
Cohort Study | Age at menopause and risk of heart failure and atrial fibrillation.
5 Aug, 2022 | 14:38h | UTCAge at menopause and risk of heart failure and atrial fibrillation: a nationwide cohort study – European Heart Journal (link to abstract – $ for full-text)
Editorial: Premature menopause and cardiovascular disease: can we blame estrogen? – European Heart Journal
News Release: Premature menopause is associated with increased risk of heart problems – European Society of Cardiology
Cohort study | Adults with Type 2 Diabetes and nonalcoholic fatty liver disease are at increased risk of severe hypoglycemia.
5 Aug, 2022 | 14:30h | UTCCommentary: Consider Fatty Liver Disease for Hypoglycemia Risk in Diabetes – JAMA Network Open (free registration required)
Commentary on Twitter
In this cohort study, participants with type 2 diabetes and nonalcoholic fatty liver disease without cirrhosis had a 26% increased risk of severe hypoglycemia diabetes independent of obesity status. https://t.co/Zh9tHkOmOa
— JAMA Network Open (@JAMANetworkOpen) February 23, 2022