Family Medicine
Guardianship | A medicolegal review for clinicians.
22 Nov, 2022 | 13:33h | UTCGuardianship: A medicolegal review for clinicians – Journal of the American Geriatrics Society
M-A | Burden of respiratory syncytial virus infection in older and high-risk adults in developed countries.
22 Nov, 2022 | 13:05h | UTC
Post-trial follow-up | A brief intervention to prevent alcohol use can have sustained effects among high-risk adolescents.
22 Nov, 2022 | 13:08h | UTC
Commentary on Twitter
RCT: Personality-targeted school-based prevention program “Preventure” can effectively reduce alcohol-related harms up to 7 years later, showing the meaningful & sustained benefits of school-based prevention programs. @theMatilda_USyd https://t.co/HuoZZluc6I #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 17, 2022
RCT | New drug can improve constipation in patients with Parkinson Disease.
22 Nov, 2022 | 13:00h | UTCOral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
New Drug Could Ease Parkinson’s-Related Constipation – HealthDay
Commentary on Twitter
A #RTC of 150 persons with #ParkinsonDisease has found that ENT-01 is safe for up to 25 days of treatment and significantly improves constipation and possibly neurological symptoms: https://t.co/JdDhaHiFOA @MayoClinic pic.twitter.com/IWWCBzvrWV
— Annals of Int Med (@AnnalsofIM) November 8, 2022
RCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM.
21 Nov, 2022 | 14:45h | UTCRCT | Intermittently scanned continuous glucose monitoring vs. fingerstick testing for Type 1 DM.
Intermittently Scanned Continuous Glucose Monitoring for Type 1 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Continuous Monitoring Outperforms Fingerstick Testing in Patients With T1D, High Glycated Hemoglobin – AJMC
Commentary on Twitter
In persons with type 1 diabetes, intermittently scanned continuous glucose monitoring led to significantly lower glycated hemoglobin levels than participant monitoring with fingerstick testing. https://t.co/2JkNKDyoQJ pic.twitter.com/CXEcARsLD8
— NEJM (@NEJM) October 5, 2022
RCT | The effects of modifying amount and type of dietary carbohydrate on esophageal reflux symptoms.
21 Nov, 2022 | 14:42h | UTCCommentary: Study finds that reducing intake of simple sugars improves GERD – Vanderbilt University
M-A | Global monkeypox case hospitalization rates.
21 Nov, 2022 | 14:36h | UTCRelated:
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series.
21 Nov, 2022 | 14:35h | UTCCommentaries:
Study describes monkeypox in women; CDC warns of Tpoxx resistance – CIDRAP
Related:
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Cohort Study | Association of antidepressant use during pregnancy with risk of neurodevelopmental disorders in children.
21 Nov, 2022 | 14:33h | UTCAssociation of Antidepressant Use During Pregnancy With Risk of Neurodevelopmental Disorders in Children – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Antidepressants in Pregnancy Do Not Affect Child Neurodevelopment – HealthDay
Commentary on Twitter
https://twitter.com/JAMAInternalMed/status/1593046260440776704
M-A | Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders.
21 Nov, 2022 | 14:11h | UTC
Commentary on Twitter
https://twitter.com/BJOGTweets/status/1578676322095742977
M-A | Comparative benefits and harms of individual opioids for chronic non-cancer pain.
21 Nov, 2022 | 13:34h | UTC
Commentary on Twitter
https://twitter.com/BJAJournals/status/1552579835217821698
RCT | Influenza vaccine to reduce adverse vascular events in patients with heart failure.
18 Nov, 2022 | 13:26h | UTCCommentary:
Flu vaccines cut pneumonia, cardiovascular issues in heart failure patients – CIDRAP
Flu Shot Could Be Lifesaver for Folks With Heart Failure – HealthDay
SR | There is insufficient evidence to recommend Ginkgo biloba for tinnitus.
18 Nov, 2022 | 13:19h | UTCGinkgo biloba for tinnitus – Cochrane Library
Summary: Ginkgo biloba herbal supplement for tinnitus – Cochrane Library
M-A | Efficacy and safety of treatments for different stages of syphilis.
18 Nov, 2022 | 13:20h | UTC
Retrospective Cohort Study | Risk of CKD following detection of microscopic hematuria.
18 Nov, 2022 | 13:11h | UTCNews Release: Persistent hematuria associated with strong risks of chronic kidney disease – National Kidney Foundation
M-A | Pharmacological interventions on smoking cessation.
18 Nov, 2022 | 13:12h | UTC
RCT | Extending the duration of prequit treatment with varenicline did not increase smoking abstinence rates.
17 Nov, 2022 | 12:22h | UTC
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1591128623947591680
Mild-to-moderate kidney dysfunction and cardiovascular disease: observational and mendelian randomization analyses.
17 Nov, 2022 | 12:18h | UTC
Commentary on Twitter
https://twitter.com/CircAHA/status/1587897418989080577
USPSTF Statement | There is insufficient evidence to recommend routine screening for obstructive sleep apnea.
16 Nov, 2022 | 13:46h | UTCEvidence Report: Screening for Obstructive Sleep Apnea in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
JAMA Patient Page: Screening for Obstructive Sleep Apnea
Author Interview: USPSTF Recommendation: Screening for Obstructive Sleep Apnea in Adults
Commentary: USPSTF: Evidence Inadequate for Recommending OSA Screening – HealthDay
RCT | In patients with end-stage ankle osteoarthritis, total ankle replacement and arthrodesis resulted in comparable results.
16 Nov, 2022 | 13:45h | UTCTotal Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
News Release: Trial shows benefits of two forms of ankle surgery for osteoarthritis – University College London
Summary for Patients: Total Ankle Replacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis
M-A | A short course of antibiotics is noninferior to long-course therapy in children with nonsevere pneumonia.
16 Nov, 2022 | 13:43h | UTCShort-Course vs Long-Course Antibiotic Therapy for Children With Nonsevere Community-Acquired Pneumonia: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
Commentary: Review: Shorter antibiotic course sufficient for kids with pneumonia – CIDRAP
Related:
ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections
RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.
Meta-Analysis: Efficacy of Short-Course Antibiotic Treatments for Community-Acquired Pneumonia
RCT | Comparative effects of low-dose rosuvastatin vs. dietary supplements on lipids and inflammatory biomarkers.
16 Nov, 2022 | 13:41h | UTCNews Release: 6 common “heart-health” supplements ineffective at lowering cholesterol compared to statins – American Heart Association
Commentaries:
Study – For Lowering Cholesterol, Statins Work, Supplements Don’t – Science-Based Medicine
Statins vs. supplements: New study finds one is ‘vastly superior’ to cut cholesterol – NPR
Cohort Study | Childhood adversity and cardiovascular disease in early adulthood.
16 Nov, 2022 | 13:29h | UTCChildhood adversity and cardiovascular disease in early adulthood: a Danish cohort study – European Heart Journal (free for a limited period)
Commentary from the author on Twitter
https://twitter.com/HulvejRod/status/1592520830155886593
RCT | Genicular nerve block offers short-term pain relief in patients with knee osteoarthritis.
15 Nov, 2022 | 12:50h | UTCCommentary: Genicular nerve block may provide short-term pain relief for knee osteoarthritis – medwire News
M-A | SGLT2 inhibitors reduce the risk of kidney disease progression and AKI, irrespective of diabetes status.
11 Nov, 2022 | 14:04h | UTCCommentaries:
Meta-analysis backs SGLT2 inhibitors for kidney disease – medwire News
EMPA-KIDNEY: Empagliflozin a ‘Win’ for Patients With CKD – TCTMD
Commentary on Twitter
Our SGLT2 Trialists Consortium meta-analysis *the largest ever* in @TheLancet https://t.co/YlWkRQTDAW
Definitive evidence that SGLT2i ⬇️:
– Kidney failure
– AKI
– CV death
– All-cause deathRegardless of diabetes
Led by @NatalieStaplin @RichardHaynes3 @willkidney #AHA22 pic.twitter.com/uAX15mD9XY
— Brendon Neuen (@brendonneuen) November 6, 2022
Under a Creative Commons Attribution (CC BY 4.0) License