Family Medicine
Viewpoint: Management of Parkinson Disease in 2017
26 Aug, 2017 | 20:17h | UTCViewpoint: Management of Parkinson Disease in 2017: Personalized Approaches for Patient-Specific Needs – JAMA (free)
Study: Local Anesthetic With or Without Corticosteroid for Lumbar Spinal Stenosis
26 Aug, 2017 | 16:22h | UTCSource: ACP Journal Wise ($)
“Epidural injections of corticosteroid plus lidocaine offered no benefits from 6 weeks to 12 months beyond that of injections of lidocaine alone”
Systematic Review: Low molecular weight heparin for prevention of venous thromboembolism in patients with lower-limb immobilization
26 Aug, 2017 | 19:37h | UTCLow molecular weight heparin for prevention of venous thromboembolism in patients with lower-limb immobilization – Cochrane Library (link to abstract – $ for full-text)
“Moderate-quality evidence showed that the use of LMWH in outpatients reduced DVT when immobilization of the lower limb was required, when compared with no prophylaxis or placebo”.
Meta-analysis: visual inspection using acetic acid or lugol iodine to detect cervical precancer
26 Aug, 2017 | 16:28h | UTCAccuracy of combinations of visual inspection using acetic acid or lugol iodine to detect cervical precancer: a meta-analysis – BJOG (link to abstract – $ for full-text)
Source: ACP Journal Wise ($)
“Although imperfect, VILI (Lugol’s iodine) alone appeared to be the most useful visual screening strategy”.
Systematic Review: Medical Treatment of Nocturia in Men with Lower Urinary Tract Symptoms
26 Aug, 2017 | 16:52h | UTCSource: ACP Journal Wise ($)
Study: Gastrointestinal Safety of Direct Oral Anticoagulants
26 Aug, 2017 | 16:46h | UTCCommentary: Which NOACS are riskiest for gastrointestinal bleeding? – Pharmacy News (free)
Source: ACP Journal Club ($)
Observational study suggests Apixaban may be associated with a more favorable gastrointestinal safety profile. Further randomized trials are needed to confirm these findings.
Systematic review: Interventions to Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia
26 Aug, 2017 | 16:07h | UTC
Systematic Review: Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy
26 Aug, 2017 | 16:05h | UTCSystematic Review: Preventing Complications and Treating Symptoms of Diabetic Peripheral Neuropathy – Agency for Healthcare Research and Quality (US) (free)
Review: Lymphedema: From diagnosis to treatment
26 Aug, 2017 | 15:59h | UTCLymphedema: From diagnosis to treatment – Turkish Journal of Surgery (free)
Review: Drug-induced liver injury
26 Aug, 2017 | 15:48h | UTCReview: Drug-induced liver injury: recent advances in diagnosis and risk assessment – Gut (free)
Guideline: treatment of hypertension in people with diabetes
24 Aug, 2017 | 23:17h | UTCDiabetes and Hypertension: A Position Statement by the American Diabetes Association (free) (RT @Abraham_RMI and @ADA_Journals see Tweet)
Commentary: ADA Offers Position Statement on Diabetes and Hypertension – AJMC (free)
“the guideline continues the advice that most patients with diabetes should be treated to a blood pressure goal of <140/90 mm Hg; a goal of <130/80 can be considered for patients who have other cardiovascular risk factors” (from AJMC)
Guideline: use of imaging in the clinical management of peripheral joint osteoarthritis
24 Aug, 2017 | 23:09h | UTC
The Case for a Breakfast Feast
24 Aug, 2017 | 23:13h | UTCThe Case for a Breakfast Feast – The New York Times (free)
Related article: Meal Frequency and Timing Are Associated with Changes in Body Mass Index in Adventist Health Study 2 – The Journal of Nutrition (link to abstract – $ for full-text)
Systematic Review and Meta-analysis: Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism
24 Aug, 2017 | 20:41h | UTCScreening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism: A Systematic Review and Meta-analysis of Individual Patient Data – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Outcomes of limited cancer screening after unprovoked VTE similar to extensive screening – ACP Hospitalist (free) AND Cancer Screening Not Recommended in Patients With VTEs – Medscape (free registration required) AND Extensive cancer screening may not improve outcomes for patients with unprovoked venous thromboembolism – 2 Minute Medicine (free) AND Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism – ASCO Post (free)
Randomized Clinical Trial: Oral Steroid Does Not Reduce Symptoms in Lower Respiratory Tract Infection
24 Aug, 2017 | 20:43h | UTCEffect of Oral Prednisolone on Symptom Duration and Severity in Nonasthmatic Adults With Acute Lower Respiratory Tract Infection: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Oral Steroid Does Not Reduce Lower Respiratory Tract Infection Symptoms in Nonasthmatic Adults – JAMA Network (free) AND No Benefit for Oral Steroids in Lower Respiratory Tract Infection – Medscape (free registration required) AND Don’t use steroids for chest infections, GPs advised – Pulse (free)
In patients with acute respiratory infection, without evidence of pneumonia or asthma, the addition of corticosteroids did not reduce symptom duration or severity.
Study: Longer sleep is associated with lower BMI and favorable metabolic profiles
24 Aug, 2017 | 20:38h | UTCCommentaries: Short sleep linked to body mass, waist size – Reuters (free) AND Insufficient sleep may be adding to your waistline – University of Leeds, via Science Daily (free)
Guidelines: diagnosis and management of noncystic fibrosis bronchiectasis
22 Aug, 2017 | 20:27h | UTC
Study: Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage
22 Aug, 2017 | 19:58h | UTCCommentaries: Weight Loss Can Slow Down Knee Joint Degeneration – RSNA Press Release (free) AND Osteoarthritis: Knee joint degeneration slowed with weight loss, study confirms – Medical News Today (free)
Study: Particulate Matter Exposure and Stress Hormone Levels
22 Aug, 2017 | 18:36h | UTCCommentaries: Air pollution ups stress hormones, alters metabolismo – Reuters (free) AND AND Novel Study Shows How Air Pollution Increases CVD Risk – MedPage Today (free registration required) AND Air pollution linked to cardiovascular disease; air purifiers may lessen impact – American Heart Association, via Science Daily (free)
Related: The cost of a polluted environment: 1.7 million child deaths a year, says WHO – World Health Organization (free) AND Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015 – The Lancet (free) AND Death in the Air: Air Pollution Costs Money and Lives – World Bank (free infographic and report)
Global Burden of Sugar-Related Dental Diseases in 168 Countries and Corresponding Health Care Costs
22 Aug, 2017 | 18:55h | UTCGlobal Burden of Sugar-Related Dental Diseases in 168 Countries and Corresponding Health Care Costs – Journal of Dental Research (link to abstract – $ for full-text)
Commentaries: High sugar consumption gives rise to dental treatment costs in the billions – Science Daily (free)
“Worldwide, people are eating far too much sugar. This has negative consequences for their teeth and for their purses: seen at the global level, the costs of dental treatment are currently running at around $172 billion”
Study: Reductions in Acute Gastroenteritis–Related Hospitalizations and Associated Costs After Implementation of Rotavirus Vaccines
22 Aug, 2017 | 19:06h | UTCCommentary: Rotavirus vaccines continue to reduce diarrhea hospitalizations, medical costs in US kids – Medical News Today (free) AND Study: Rotavirus vaccine cuts healthcare costs in US children – CIDRAP (free)
Study: Dexamethasone vs Placebo on Acute Sore Throat in Adults
22 Aug, 2017 | 15:00h | UTCMultimedia: Author Interview (free) AND JAMA Report Video (free)
Commentaries: Study Examines Effectiveness of Steroid Medication for Sore Throat – The JAMA Network (free) AND Corticosteroids for sore throat: a mixed bag of results – Clinical Advisor (free)
Source: ACP Journal Club ($)
Dexamethasone increased complete symptom resolution at 48 hours (35.4% vs 27.1%), but not at 24 hours. Trade-offs between the benefits and risks of dexamethasone in this situation are uncertain.
Study: Gastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding
22 Aug, 2017 | 15:19h | UTCGastrointestinal safety of celecoxib versus naproxen in patients with cardiothrombotic diseases and arthritis after upper gastrointestinal bleeding (CONCERN): an industry-independent, double-blind, double-dummy, randomised trial – The Lancet (link to abstract – $ for full-text)
Source: ACP Journal Club
In this study, patients at high risk of both cardiovascular and gastrointestinal events who required concomitant aspirin and NSAID, celecoxib associated with a proton pump inhibitor led to less recurrent gastrointestinal bleeding when compared to naproxen associated with a proton pump inhibitor (5.6% vs 12.3%).
Systematic Review: Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease
22 Aug, 2017 | 15:32h | UTCBenefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Benefits and harms of osteoporosis medications unclear for patients with CKD – Medical News Today (free) AND Benefits and harms of osteoporosis medications unclear for patients with CKD – 2 Minute Medicine (free)
Source: ACP Journal Club ($)
Study: Risk of Arterial Thromboembolism in Patients With Cancer
22 Aug, 2017 | 14:44h | UTCRisk of Arterial Thromboembolism in Patients With Cancer – Journal of The American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Cancer Patients at Heightened Risk for Arterial Thromboembolism – American College of Cardiology, Latest in Cardiology (free) AND Thromboembolism Risk Doubled in Cancer Patients – Medscape (free registration required) AND Cancer patients carry double the short-term risk of arterial thromboembolism – Cardiovascular Business (free) AND Short-Term Risk of Arterial Thromboembolism in Newly Diagnosed Patients With Cancer – ASCO Post (free)