Study: Dexamethasone vs Placebo on Acute Sore Throat in Adults

Effect of Oral Dexamethasone Without Immediate Antibiotics vs Placebo on Acute Sore Throat in Adults: A Randomized Clinical Trial – JAMA (free)

Multimedia: Author Interview (free) AND JAMA Report Video (free)

Commentaries: Study Examines Effectiveness of Steroid Medication for Sore Throat – The JAMA Network (free) AND Corticosteroids for sore throat: a mixed bag of results – Clinical Advisor (free)

Source: ACP Journal Club ($)

Dexamethasone increased complete symptom resolution at 48 hours (35.4% vs 27.1%), but not at 24 hours. Trade-offs between the benefits and risks of dexamethasone in this situation are uncertain.