Family Medicine
Review: topical nonsteroid therapy in atopic dermatitis
14 Apr, 2018 | 18:26h | UTCAtopic dermatitis: a review of topical nonsteroid therapy – Drugs in Context (free)
Case-crossover study: spikes in air pollution linked to increased risk of lower respiratory infections
14 Apr, 2018 | 18:22h | UTCShort-term Elevation of Fine Particulate Matter Air Pollution and Acute Lower Respiratory Infection – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Brief SExposure to Tiny Air Pollution Particles Triggers Childhood Lung Infections – Intermountain Medical Center, via NewsWise (free) AND Spikes in air pollution can heighten risk of chest infections, research suggests – The Guardian (free) AND Air Pollution May Pose Serious Risks to Young Children – The New York Times (10 articles per month are free) AND Short-Term Pollution Spikes Trigger Lung Infections in Young Kids – MedPage Today (free registration required)
Meta-analysis: antibiotics for the treatment of skin and soft tissue abscesses
13 Apr, 2018 | 01:41h | UTCCommentary: Meta-Analysis Favors Antibiotics After Drainage of Skin Abscesses – NEJM Journal Watch (free)
See related guideline with infographic: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free) AND Meta-Analysis: Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis – BMJ Open (free)
AHA scientific statement: evaluation and management of right-sided heart failure
13 Apr, 2018 | 01:44h | UTCCommentary: Taking the Good With the Bad – Assigning Value and Blame to the Right Heart in Cardiovascular Disease (free)
Top Ten Things to Know: Evaluation and Management of Right-Sided Heart Failure (free PDF)
Guidelines for the antibiotic treatment of community-acquired urinary tract infections
13 Apr, 2018 | 01:40h | UTC
Research: respiratory infections as triggers for acute myocardial infarction and stroke
13 Apr, 2018 | 01:35h | UTCCommentaries: Flu and pneumonia infections increase risk of having a heart attack and stroke – European Respiratory Foundation, via Eurekalert (free) AND Do Pneumococcal and Respiratory Virus Infections Trigger Cardiovascular Morbidity? – NEJM Journal Watch (free for a limited period)
See also: related study published recently showing a similar six-fold increase in myocardial infarctions in the week following a flu diagnosis (link to abstract and commentaries).
Cohort study: solid fuel use and cardiovascular and all-cause mortality in rural China
13 Apr, 2018 | 01:20h | UTCAssociation of Solid Fuel Use With Risk of Cardiovascular and All-Cause Mortality in Rural China – JAMA (link to abstract – $ for full-text)
Commentaries: Solid Fuels Used for Cooking and Heating Pose Cardiovascular and Mortality Risks – TCTMD (free) AND Solid fuel use linked to increased cardiovascular and all-cause mortality – 2 Minute Medicine (free)
Systematic review: antidepressants versus placebo for panic disorder in adults
13 Apr, 2018 | 01:17h | UTCAntidepressants versus placebo for panic disorder in adults – Cochrane Library (link to abstract – $ for full-text)
Summary: Antidepressants for panic disorder in adults – Cochrane Library (free)
Commentary: Antidepressants are moderately effective in panic disorder – Univadis (free registration required)
Retrospective cohort: clinical usefulness of imaging and blood cultures in cellulitis evaluation
13 Apr, 2018 | 01:11h | UTCClinical Usefulness of Imaging and Blood Cultures in Cellulitis Evaluation – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Unnecessary blood tests and imaging common in cellulitis hospitalizations, study finds – ACP Hospitalist (free)
Cross-sectional analysis: noise exposure in workplace tied to hypertension and high cholesterol
13 Apr, 2018 | 01:03h | UTCCardiovascular conditions, hearing difficulty, and occupational noise exposure within US industries and occupations – American Journal of Industrial Medicine (free PDF for a limited period)
Commentaries: Noisy workplace tied to high blood pressure and high cholesterol – Reuters (free) AND Noisy Workplace Linked to Hypertension, Hyperlipidemia – Medscape (free registration required)
Cohort study: multidrug-resistant organisms in newly admitted nursing facility patients
13 Apr, 2018 | 00:59h | UTCCommentaries: Study finds high rate of MDRO colonization in new nursing home patients – CIDRAP (free)
Systematic review: exercise improves intermittent claudication leg pain on walking
13 Apr, 2018 | 00:54h | UTCExercise improves intermittent claudication leg pain on walking – NIHR Signal (free)
Original article: Exercise for intermittent claudication – Cochrane Library (free)
Perspective: five keys to leading transformational change in primary care
13 Apr, 2018 | 00:51h | UTCFive Keys to Leading Transformational Change in Primary Care – NEJM Catalyst (free)
Meta-analysis: weight loss as a predictor of cancer in primary care
12 Apr, 2018 | 02:49h | UTCCommentaries: Weight loss is an important predictor of cancer – University of Oxford (free)
Guideline: management of alcohol-related liver disease
12 Apr, 2018 | 02:46h | UTC
Cohort study: associations of exercise and genetic risk with cardiovascular disease
12 Apr, 2018 | 02:40h | UTCAssociations of Fitness, Physical Activity, Strength, and Genetic Risk With Cardiovascular Disease: Longitudinal Analyses in the UK Biobank Study – Circulation (free PDF for a limited period)
Commentaries: Outrunning Your Genes: Exercise Offsets CVD Events Among High-Risk Subjects – TCTMD (free) AND When heart disease runs in the family, exercise tied to lower risk – Reuters (free)
Guideline: treatment of Hepatitis C
12 Apr, 2018 | 02:42h | UTCEASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
Systematic review: honey for acute cough in children
12 Apr, 2018 | 02:33h | UTCHoney for acute cough in children – Cochrane Library (link to abstract – $ for full-text)
Summary: Honey for acute cough in children – Cochrane Library (free)
“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”
Meta-analysis: effect of pasta in the context of low-glycaemic index diet on body weight and markers of adiposity
12 Apr, 2018 | 02:35h | UTCCommentary: Pasta unlikely to cause weight gain as part of a healthy diet – NHS Choices (free)
Guideline: evaluation and management of testosterone deficiency
12 Apr, 2018 | 02:29h | UTCGuideline: Evaluation and Management of Testosterone Deficiency – American Urological Association (free)
Commentary: AUA: New Guidelines for Diagnosis, Management of Testosterone Deficiency – MPR (free)
Related Guideline: Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
Guideline: Iron Deficient Anemia
12 Apr, 2018 | 02:14h | UTCClinical Practice Guideline: Iron Deficient Anemia – Toward Optimized Practice (TOP) (free PDF)
See also: Summary (free PDF)
Related: see all TOP Clinical Practice Guidelines, a practical resource for Family Physicians at the point of care.
Cohort study: SSRI exposure during pregnancy and MRI-assessed brain abnormalities in infants
12 Apr, 2018 | 02:20h | UTCAssociations Between Brain Structure and Connectivity in Infants and Exposure to Selective Serotonin Reuptake Inhibitors During Pregnancy – JAMA Pediatrics (free for a limited period)
Author interview: Associations Between SSRI Exposure During Pregnancy and MRI-Assessed Brain Structure and Connectivity in Infants (free)
Commentaries: We’re beginning to learn how moms’ antidepressants can affect fetuses – VOX (free) AND MRI study finds prenatal exposure to certain antidepressants may alter brain development – Health Imaging (free) AND SSRI use in pregnancy may affect fetal brain development – OnMedica (free) AND Antidepressants in pregnancy tied to changes in babies’ brains – Reuters (free)
Cohort study: childhood predictors of lung function trajectories and future COPD risk
12 Apr, 2018 | 02:04h | UTCChildhood predictors of lung function trajectories and future COPD risk: a prospective cohort study from the first to the sixth decade of life – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Related article: Lung function trajectories from pre-school age to adulthood and their associations with early life factors: a retrospective analysis of three population-based birth cohort studies – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentaries: Three-quarters of COPD cases are linked to childhood risk factors that are exacerbated in adulthood – The Lancet, via ScienceDaily (free) AND Early intervention may minimise later lung problems – The Melbourne Newsroom (free) AND COPD Risk Factors Evident Early in Life – NEJM Physician’s First Watch (free)
Cohort study: time for chronic dialysis initiation and mortality
12 Apr, 2018 | 02:11h | UTCDialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs – JAMA Internal Medicine (free for a limited period)
Invited commentary: Appropriate Time for Chronic Dialysis Initiation: A Cause for Humility (free for a limited period)
Related articles: Treatment decisions for older adults with advanced chronic kidney disease – BMC Nephrology (free) AND Timing of Dialysis Initiation – What Has Changed Since IDEAL? – Seminars in Nephrology (free)
Perspective: many people taking antidepressants discover they cannot quit
12 Apr, 2018 | 02:01h | UTCMany People Taking Antidepressants Discover They Cannot Quit – The New York Times (10 articles per month are free)