Family Medicine
Review: The Art of Cardiovascular Risk Assessment
24 May, 2018 | 23:16h | UTCThe art of cardiovascular risk assessment – Clinical Cardiology (free)
Review: Pitfalls on the Replacement Therapy for Hypothyroidism
24 May, 2018 | 23:13h | UTC
Cohort Study: Gestational Hypertension and Future Risk of Cardiovascular Disease
24 May, 2018 | 23:02h | UTCAssociation Between Gestational Hypertension and Risk of Cardiovascular Disease Among 617 589 Norwegian Women – Journal of the American Heart Association (free for a limited period)
Editorial: Cardiovascular Sequels of Hypertension in Pregnancy (free for a limited period)
Related Studies: All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease (free PDF and commentaries) AND Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease (link to abstract and free commentaries)
Meta-Analysis: Longitudinal Association Between Diabetes and Anxiety
24 May, 2018 | 22:57h | UTCInvestigating the longitudinal association between diabetes and anxiety: a systematic review and meta‐analysis – Diabetic Medicine (free) (via @kamleshkhunti)
Review: Management Pathways for Solitary Pulmonary Nodules
24 May, 2018 | 22:41h | UTCManagement pathways for solitary pulmonary nodules – Journal of Thoracic Disease (free)
ACOG Committee Opinion: Evaluating the Endometrium in Postmenopausal Bleeding
24 May, 2018 | 22:39h | UTCCommentary: Endometrial Evaluation in Women with Postmenopausal Bleeding – NEJM Journal Watch (free for a limited period)
Randomized Trial: In Black Infants Who Were Born Preterm, Vitamin D Reduced Recurrent Wheezing
24 May, 2018 | 22:32h | UTCEffect of Vitamin D Supplementation on Recurrent Wheezing in Black Infants Who Were Born Preterm: The D-Wheeze Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Vitamin D Supplementation May Help Reduce Wheezing in Black Preemies – NEJM Physician’s First Watch (free)
Review: Laboratory Diagnosis of Platelet Function Disorders
24 May, 2018 | 22:25h | UTCSource: Critical Care Reviews Newsletter
Retrospective Cohort: Atrial Fibrillation Burden and Risk of Stroke in Adults with Paroxysmal Atrial Fibrillation
23 May, 2018 | 12:48h | UTCCommentaries: Atrial Fibrillation Burden and Stroke Risk – American College of Cardiology (free) AND Greater burden of atrial fibrillation linked to higher stroke risk – Kaiser Permanente, via EurekAlert (free)
Review: Managing Depression in Patients with CAD
23 May, 2018 | 12:47h | UTCCommentaries: Depression in Patients With CAD – American College of Cardiology (free) AND Early Depression Diagnosis is Deadly Serious for Patients with Coronary Artery Disease – Florida State University, via NewsWise (free)
Review: Autism Spectrum Disorder
23 May, 2018 | 12:46h | UTCAutism spectrum disorder: advances in diagnosis and evaluation – The BMJ (free for a limited period)
Richard Lehman’s weekly journal review – 21 May 2018
23 May, 2018 | 12:45h | UTCRichard Lehman’s weekly journal review, 21 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Randomized Controlled Trial: Dupilumab in Glucocorticoid-Dependent Severe Asthma
23 May, 2018 | 12:39h | UTCRelated Article: Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma – New England Journal of Medicine (free)
Editorial: New Biologics for Asthma (free)
Commentary: Dupilumab Improves Severe Asthma – NEJM Physician’s First Watch (free)
Cohort Study: Egg Consumption and Cardiovascular Disease
23 May, 2018 | 12:32h | UTCCommentaries: BMJ’s scrambled message on eggs and heart disease: a recipe for rotten news coverage – Health News Review (free) AND Expert reaction to eggs and CVD – Science Media Centre (free) AND No, Eating Eggs Will NOT Protect You From Cardiovascular Death – The Methods Man (free)
Pro/Con Debate: CTA as the Initial Test in Stable Angina
23 May, 2018 | 12:33h | UTCPro: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)
Con: Coronary CTA Should Be the Initial Test in Most Patients with Stable Chest Pain (free)
Meta-Analysis: Aldosterone Antagonists for ST-Segment Elevation Myocardial Infarction Without Heart Failure
23 May, 2018 | 12:28h | UTCAldosterone Antagonist Therapy and Mortality in Patients With ST-Segment Elevation Myocardial Infarction Without Heart Failure: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Mineralocorticoid Receptor Antagonists in ST-Segment Elevation Myocardial Infarction – JAMA Internal Medicine (free for a limited period)
Aldosterone antagonists are beneficial for patients with STEMI and reduced ejection fraction. This meta-analysis suggests that patients with STEMI and LVEF greater than 40% or without heart failure also have improved outcomes with aldosterone antagonists.
Register-based Retrospective Study: Pediatric Exposures to ADHD Medications are an Increasing Problem
23 May, 2018 | 12:15h | UTCPediatric ADHD Medication Exposures Reported to US Poison Control Centers – Pediatrics (link to abstract – $ for full-text)
Commentaries: Unnecessary and accidental use of ADHD drugs increases over 60%, study suggests – CNN (free) AND Add ADHD Meds To Call Burden For Poison Control Centers – American Council on Science and Health (free) AND As ADHD Diagnoses Increased, So Did Calls to Poison Control – U.S. News (free) AND More U.S. kids overdosing on ADHD drugs – Reuters (free)
Retrospective Cohort: More Patients Choosing Active Surveillance for Low-Risk Prostate Cancer
23 May, 2018 | 12:17h | UTCUse of Conservative Management for Low-Risk Prostate Cancer in the Veterans Affairs Integrated Health Care System From 2005-2015 – JAMA (free for a limited period)
Commentaries: VA health care successfully reduces ‘rush to treatment’ rates for low-risk prostate cancer – eCancer News (free) AND Watching but not treating cancer can be hard. Sometimes it’s the right approach – The Washington Post (a few articles per month are free)
Guideline Summary: CVD and Risk Management Standards in Diabetes
21 May, 2018 | 13:20h | UTCSummary with Key Points: CVD and Risk Management Standards in Diabetes – American College of Cardiology (free)
Original Synopsis: Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018 – Annals of Internal Medicine (free)
Meta-Analysis: Dose Increase vs. Unchanged Continuation of Antidepressants After Initial Treatment Failure
21 May, 2018 | 13:11h | UTCDose Increase Versus Unchanged Continuation of Antidepressants After Initial Antidepressant Treatment Failure in Patients With Major Depressive Disorder: A Systematic Review and Meta-Analysis of Randomized, Double-Blind Trials – The Journal of Clinical Psychiatry (link to abstract – $ for full-text)
Commentary: Depression: boosting SSRIs doesn’t work – Univadis (free registration required)
“Meta-analysis: there is evidence from RCTs against increasing the dose of SSRIs (with the possible exception of citalopram) in adult patients with major depression and antidepressant treatment failure” (via @psychopharmacol see Tweet)
Review: Pitfalls on the Replacement Therapy for Hypothyroidism
21 May, 2018 | 13:03h | UTC
Randomized Trial: Ibuprofen Alone For Uncomplicated UTI
18 May, 2018 | 02:41h | UTCCommentary: Ibuprofen alone not an option for simple UTIs, study finds – CIDRAP (free) AND Randomized trial finds ibuprofen not a safe alternative to antibiotics for UTIs – PLOS, via ScienceDaily (free)
Related Research: Symptomatic treatment of uncomplicated lower urinary tract infections in the ambulatory setting: randomised, double blind trial- The BMJ (free)
Cohort Study: Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke
18 May, 2018 | 02:39h | UTCFive-Year Risk of Stroke after TIA or Minor Ischemic Stroke – New England Journal of Medicine (free)
Commentary: Elevated Stroke Risk Continues for 5 Years After TIA – NEJM Physician’s First Watch (free) AND Five Years after TIA or Minor Stroke, Second-Event Risk Persists – MedPage Today (free)
Randomized Trial: Dual Antiplatelet Therapy in Acute Ischemic Stroke and High-Risk TIA
18 May, 2018 | 02:36h | UTCClopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA – New England Journal of Medicine (free)
Editorial: Antiplatelet Therapy after Ischemic Stroke or TIA (free)
Commentary: Dual Antiplatelet Therapy or Aspirin Alone After TIA or Minor Stroke? – NEJM Physician’s First Watch (free)
Clinical Guideline: Pharmacotherapy for Neuropathic Pain
18 May, 2018 | 02:33h | UTC