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Randomized Trial: Medical Expulsive Therapy Not Effective for Kidney Stone Passage

18 Jun, 2018 | 23:18h | UTC

Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)

Editorial: Medical Expulsive Therapy for Ureteral Stones—Stone Age Medicine (free)

Commentaries: Recent Clinical Trial Finds Tamsulosin Not Effective in Kidney Stone Passage – George Washington University, via NewsWise (free) AND For Passing Smaller Ureteral Stones, Tamsulosin May Be No Better Than Placebo – NEJM Physician’s First Watch (free)

 


Richard Lehman’s journal review, 18 June 2018

18 Jun, 2018 | 23:18h | UTC

Richard Lehman’s journal review, 18 June 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Randomized Trial: Metabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths

18 Jun, 2018 | 22:59h | UTC

Metabolic Effects of Antipsychotics on Adiposity and Insulin Sensitivity in Youths: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries: Study First to Show Antipsychotic Medication Use in Youths Increases Diabetes Risk, Body Fat – Florida Atlantic University, via NewsWise (free) AND Rapid Weight Gain, Decreased Insulin Sensitivity Found in Youth Taking SGAs for First Time – Psychiatric News Alert (free) AND Kids on Antipsychotics May See Adverse Metabolic Effects – MedPage Today (free registration required)

 


Perspective: Gaming Addiction as a Mental Disorder

18 Jun, 2018 | 15:01h | UTC

Gaming addiction as a mental disorder: it’s premature to pathologise players – The Conversation (free) AND

Related: Gaming addiction classified as mental health disorder by WHO – Reuters (free) AND WHO classifies ‘gaming disorder’ as mental health condition – CNN (free)

 


Randomized Trial: Duloxetine in Patients with Knee Osteoarthritis

18 Jun, 2018 | 10:08h | UTC

A randomized, double-blind, placebo-controlled Phase III trial of duloxetine in Japanese patients with knee pain due to osteoarthritis – Journal of Pain Research (free)

 


Cohort Study: Screening Men for Abdominal Aortic Aneurysm Questioned

18 Jun, 2018 | 00:25h | UTC

Benefits and harms of screening men for abdominal aortic aneurysm in Sweden: a registry-based cohort study – The Lancet (free to abstract – $ for full-text)

Commentaries: Screening Programs for Abdominal Aortic Aneurysm Need a Rethink, Swedish Study Contends – TCTMD (free) AND Screening for aortic aneurysms in older men questioned – University of Gothemburg, via EurekAlert (free) AND Screening for Abdominal Aortic Aneurysm Questioned – NEJM Physician’s First Watch (free) AND Routine Aortic Aneurysm Screening Questioned – MedPage Today (free registration required)

 


Systematic Review: Noninvasive Nonpharmacological Treatment for Chronic Pain

15 Jun, 2018 | 02:28h | UTC

Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review – Agency for Healthcare Research and Quality (free)

See also: Evidence Summary (free PDF) and Full Report (free PDF)

 


USPSTF Draft Statement: Screening for Unhealthy Alcohol Use in Adolescents and Adults

15 Jun, 2018 | 02:27h | UTC

Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions – U.S. Preventive Services Task Force (free)

Commentary: USPSTF Again Recommends Screening for Unhealthy Alcohol Use in Adults – NEJM Physician’s First Watch (free)

 


Guideline Revisited: Diagnosis and Management of Primary Aldosteronism

15 Jun, 2018 | 02:25h | UTC

Diagnosis and management of primary aldosteronism: the Endocrine Society guideline 2016 revisited – European Journal of Endocrinology (free)

Related Guideline: The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)

 


Cohort Study: Antifungal Drug in Pregnancy Not Associated with Increased Risk of Stillbirth and Neonatal Death

15 Jun, 2018 | 02:21h | UTC

Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death – JAMA (link to abstract – $ for full-text)

Commentaries: No link found between oral antifungal drug and stillbirth – Karolinska Institutet, via ScienceDaily (free) AND Antifungal Use During Pregnancy and Risk of Stillbirth: What’s the Link? – MPR (free) AND Study Finds No Link Between Fluconazole During Pregnancy and Stillbirth or Neonatal Death – MedicalResearch.com (free) AND Oral Fluconazole for Thrush in Pregnancy Doesn’t Up Stillbirth – Medscape (free registration required)

 


Review: Dietary and Nutritional Approaches for Prevention and Management of Type 2 Diabetes

15 Jun, 2018 | 02:18h | UTC

Dietary and nutritional approaches for prevention and management of type 2 diabetes – The BMJ (free)

 


Cohort Study: High Blood Pressure in 50-year-olds Associated with Higher Risk of Dementia

15 Jun, 2018 | 02:13h | UTC

Association between systolic blood pressure and dementia in the Whitehall II cohort study: role of age, duration, and threshold used to define hypertension – European Heart Journal (free)

Commentaries: Dementia risk increased in 50-year-olds with blood pressure below hypertension threshold – European Society of Cardiology, via EurekAlert (free) AND Blood pressure below treatable threshold linked to heightened dementia risk – OnMedica (free) AND Studies: Higher blood pressure increases risk for dementia – UPI (free) AND High Blood Pressure at Age 50 Tied to Dementia Risk – The New York Times (10 articles per month are free) AND Dementia risk to 50-year-olds with raised blood pressure – study – The Guardian (free)

 


USPSTF Statement: Screening with Resting or Exercise Electrocardiography (ECG) Not Recommended

15 Jun, 2018 | 02:12h | UTC

Screening for Cardiovascular Disease Risk With Electrocardiography: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Editorials: The Screening ECG and Cardiac Risks (free) AND Screening for Cardiovascular Disease Risk With Electrocardiography (free)

JAMA Patient Page: Screening for Cardiovascular Disease Risk With ECG (free)

Author Interview: USPSTF Recommendation: Screening for Cardiovascular Disease Risk With Electrocardiography (free audio)

Commentaries: Doctors Told Not To Order Electrocardiograms For Low-Risk Patients – NPR (free) AND USPSTF Finds Insufficient Evidence For Preventative ECG Screening in Asymptomatic, Low-Risk Adults – American College of Cardiology (free)

“The USPSTF recommends against screening with resting or exercise electrocardiography (ECG) to prevent cardiovascular disease (CVD) events in asymptomatic adults at low risk of CVD events”.

 


WONCA Position Paper on Overdiagnosis and Action to be Taken

15 Jun, 2018 | 02:09h | UTC

Position Paper on Overdiagnosis and Action to be Taken – Wonca (free PDF) (via @RasoiniR)

Related: Overdiagnosis across medical disciplines: a scoping review – BMJ Open (free) Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free)

 


Cross-Sectional Survey: Prevalence of US Adults Using Medications with Depression as a Potential Adverse Effect was 37.2%

15 Jun, 2018 | 02:11h | UTC

Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States – JAMA (link to abstract – $ for full-text)

Commentaries: One-Third of US Adults May Unknowingly Use Medications That Can Cause Depression – University of Illinois at Chicago, via EurekAlert (free) AND Many U.S. adults take medicines that can cause depression – Reuters (free) AND Rx With Depression as Potential Adverse Effect Widely Used – Medscape (free registration required)

 


Cohort Study: Erectile Dysfunction as an Independent Predictor of Future Cardiovascular Events

15 Jun, 2018 | 01:52h | UTC

Erectile Dysfunction as an Independent Predictor of Future Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis – Circulation (free PDF)

AHA News Release: Erectile dysfunction means increased risk for heart disease, regardless of other risk factors (free)

Commentaries: Men With Erectile Dysfunction Are Twice As Likely to Have Heart Disease, Study Says – TIME (free) AND Erectile Dysfunction Linked To Higher Chances Of Heart Problems In Men – Medical Daily (free)

 


Research: Honey May Reduce Injury and Improve Outcomes After Accidental Button Battery Ingestion

15 Jun, 2018 | 01:51h | UTC

pH‐neutralizing esophageal irrigations as a novel mitigation strategy for button battery injury – The Laryngoscope (free)

Commentaries: Ingesting honey after swallowing button battery reduces injury and improves outcomes – Children’s Hospital of Philadelphia, via ScienceDaily (free) AND Honey + Sucralfate May Reduce Injury After Accidental Button Battery Ingestion – MPR (free)

 


Hydroxychloroquine: An Old Drug with New Relevance

15 Jun, 2018 | 01:50h | UTC

Hydroxychloroquine: An old drug with new relevance – Cleveland Clinic Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club

 


Richard Lehman’s Journal Review – 11 June 2018

15 Jun, 2018 | 01:50h | UTC

Richard Lehman’s journal review, 11 June 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Cohort Study: Tonsillectomy in Childhood Linked with Increased Risk of Respiratory Diseases

15 Jun, 2018 | 01:43h | UTC

Association of Long-Term Risk of Respiratory, Allergic, and Infectious Diseases With Removal of Adenoids and Tonsils in Childhood – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)

Commentaries: Tonsillectomy in childhood raises risk of respiratory diseases – OnMedica (free) AND Tonsillectomy, Adenoidectomy in Childhood Tied to Long-Term Health Risks – Physician’s First Watch (free) AND Tonsillectomy Risks May Outweigh Benefits – The New York Times (10 articles per month are free)

 


Perspective: What’s the Harm in Earlier Screening for Colorectal Cancer?

15 Jun, 2018 | 01:22h | UTC

What’s the harm in earlier screening for colorectal cancer? – Lown Institute (free) (via @kennylinafp)

See Original Guideline: Colorectal Cancer Screening for Average‐risk Adults (free guideline and commentaries)

 


Retrospective Review: Mild to Moderate Isolated Thrombocytopenia Associated with Good Outcomes

15 Jun, 2018 | 00:59h | UTC

Outcomes in Mild to Moderate Isolated Thrombocytopenia – Pediatrics (free)

Commentary: Isolated mild/moderate thrombocytopenia may not require intervention – 2 Minute Medicine (free)

 


Systematic Review: Nicotine Replacement Therapy vs Control for Smoking Cessation

7 Jun, 2018 | 02:55h | UTC

Nicotine replacement therapy versus control for smoking cessation – Cochrane Library (free)

Summary: Can nicotine replacement therapy (NRT) help people quit smoking? – Cochrane Library (free)

 


Review: Aspiration Pneumonia and Related Syndromes

7 Jun, 2018 | 02:54h | UTC

Aspiration Pneumonia and Related Syndromes – Mayo Clinic Proceedings (free)

 


Proof-of-concept Trial: Fecal Microbiota Transplantation for Primary Clostridium difficile Infection

7 Jun, 2018 | 02:50h | UTC

Fecal Microbiota Transplantation for Primary Clostridium difficile Infection – New England Journal of Medicine (free)

Commentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)

 


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