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Family Medicine

Randomized Trial: Effects of Treating Depression on Outcomes in Patients With Acute Coronary Syndrome

3 Aug, 2018 | 02:59h | UTC

Effect of Escitalopram vs Placebo Treatment for Depression on Long-term Cardiac Outcomes in Patients With Acute Coronary Syndrome: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

Commentaries: Treating Depression May Improve Cardiac Outcomes, Research Finds – AJMC (free) AND Treating depression may prevent repeat heart attack, study says – UPI (free)

 


Meta-Analysis: Pharmacological Treatment of Arterial Hypertension in Children and Adolescents

3 Aug, 2018 | 02:54h | UTC

Pharmacological Treatment of Arterial Hypertension in Children and Adolescents: A Network Meta-Analysis – Hypertension (free)

Commentary: Pediatric hypertension: ACEi/ARBs look like the best choice – Univadis (free)

“According to the present analysis, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers could represent the best choice as antihypertensive treatment for pediatric hypertension. However, because of the paucity of available data for the other classes of antihypertensive drugs, definitive conclusions are not allowed and further randomized controlled trials are warranted.”

 


Study: Prevalence of Depression Among New Fathers

3 Aug, 2018 | 02:55h | UTC

Prevalence of Depression Among Fathers at the Pediatric Well-Child Care Visit – JAMA Pediatrics (link to abstract – $ for full-text)

Commentaries: New dads need depression screening, too – Reuters (free) AND New Dads as Likely to Suffer From Depression as Moms, Study Suggests – Medscape (free registration required)

 


Cohort Study: Alcohol Consumption and Risk of Dementia

3 Aug, 2018 | 00:18h | UTC

Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study – The BMJ (free)

Editorial: Relation between alcohol consumption in midlife and dementia in late life (free)

Commentaries: Expert reaction to long term abstinence and heavy drinking associated with dementia – Science Media Centre (free) AND Middle-aged non-drinkers may have ‘higher risk’ of dementia – The Guardian (free)

 


Study: Medications that Reduce Emergency Hospital Admissions

27 Jul, 2018 | 01:15h | UTC

Medications that reduce emergency hospital admissions: an overview of systematic reviews and prioritisation of treatments – BMC Medicine (free) (via @OxPrimaryCare)

Commentary: The eleven best medications for reducing pressure on emergency care services – University of Oxford (free)

 


Opinion: Intensive Blood pressure Control and ‘Dementia’

26 Jul, 2018 | 20:23h | UTC

Intensive blood pressure control and ‘dementia’: another mad rush to report incomplete SPRINT findings – HealthNewsReview (free)

See also: No, A Big NIH Trial Did Not Show That Lowering Blood Pressure Will Prevent Dementia – Cardiobrief (free)

 


UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE

26 Jul, 2018 | 18:40h | UTC

UNDETECTABLE = UNTRANSMITTABLE: Public Health and HIV Viral Load Suppression – UNAIDS Explainer (free PDF)

News Release: Undetectable = Untransmittable – UNAIDS (free)

Related: Science Validates Undetectable = Untransmittable HIV Prevention Message – National Institute of Allergy and Infectious Diseases (free) AND The “Undetectable = Untransmittable” message goes global: I=I, N=N and B=B – Aidsmap (free)

 


Guideline: PFO closure vs. Antiplatelet Therapy vs. Anticoagulation for Management of Cryptogenic stroke

26 Jul, 2018 | 18:40h | UTC

Rapid Recommendations: Patent foramen ovale closure, antiplatelet therapy or anticoagulation therapy alone for management of cryptogenic stroke? A clinical practice guideline – The BMJ (free)

 


Study: Osteoporosis Treatment After Hip Fracture

26 Jul, 2018 | 18:37h | UTC

Association of Osteoporosis Medication Use After Hip Fracture With Prevention of Subsequent Nonvertebral Fractures: An Instrumental Variable Analysis – JAMA Network Open (free)

Commentaries: Osteoporosis Treatment After Hip Fracture: Bad News and Getting Worse – JAMA Network Open (free) AND Rate of Osteoporosis Drug Treatment to Prevent Recurrent Fractures Dropping – AJMC (free) AND Osteoporosis treatment often not started after hip fracture in elderly patients, study finds – ACP Internist (free)

 


Meta-analysis: Fast Food Consumption Linked to Asthma and Other Allergic Diseases

26 Jul, 2018 | 18:36h | UTC

Is the consumption of fast foods associated with asthma or other allergic diseases? – Respirology (free)

Commentary: Consumption of Fast Food Linked with Asthma and Other Allergic Diseases – Wiley (free) AND Study Links Fast Food Consumption to Severe Asthma – AJMC (free)

 


Systematic Review: Drug Therapy for Early Rheumatoid Arthritis

26 Jul, 2018 | 18:33h | UTC

Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF)

 


Retrospective Cohort: Radiation Exposure From Pediatric CT Scans and Subsequent Cancer Risk

26 Jul, 2018 | 18:31h | UTC

Radiation Exposure From Pediatric CT Scans and Subsequent Cancer Risk in the Netherlands – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)

Commentary: Pediatric CT Scans and Subsequent Malignancy Risk – The ASCO Post (free)

 


Systematic Review: Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes

26 Jul, 2018 | 18:32h | UTC

Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF)

 


Clinician’s Guide for Trending Cardiovascular Nutrition Controversies

26 Jul, 2018 | 18:21h | UTC

A Clinician’s Guide for Trending Cardiovascular Nutrition Controversies: Part II – Journal of the American College of Cardiology (free)

Related – Part I: Trending Cardiovascular Nutrition Controversies – Journal of the American College of Cardiology (free)

Commentary: Chew on This: Review Tackles Controversies in Nutrition for CV Health – TCTMD (free) AND Separating health from hype for a diet that’s kind on your heart – ABC News (free)

 


Review: Antidepressant Withdrawal Syndrome

26 Jul, 2018 | 18:18h | UTC

Antidepressant Withdrawal Syndrome – Therapeutics Initiative (free)

Related Perspective: Many People Taking Antidepressants Discover They Cannot Quit – The New York Times (10 articles per month are free)

“Antidepressants should be added to the list of drugs associated with tolerance, dependence and a withdrawal syndrome.”

“Withdrawal symptoms occur in at least one-third of patients who stop.”

 


Study: Development and Validation of a Cardiovascular Disease Risk-Prediction Model

26 Jul, 2018 | 18:17h | UTC

Development and validation of a cardiovascular disease risk-prediction model using population health surveys: the Cardiovascular Disease Population Risk Tool (CVDPoRT) – Canadian Medical Association Journal (free)

See also: Heart Attack & Stroke Calculator (free tool)

Commentaries: New health calculator can help predict heart disease risk, estimate heart age – CMAJ, via ScienceDaily (free) AND Calculator can predict heart age, risk for heart disease – UPI (free) AND Algorithm Allows Patients To Calculate Their Risk of Stroke and Heart Disease – MedicalResearch.com (free)

Related Calculators: ACC/AHA CV Risk Calculator (free) AND QRISK3-2017 Cardiovascular Disease Risk Calculator (free)

 


Richard Lehman’s journal reviews – 23 July 2018

26 Jul, 2018 | 18:04h | UTC

Richard Lehman’s journal reviews, 23 July 2018 – The BMJ Opinion (free)

Richard Lehman reviews the latest research in the top medical journals.

 


Perspective: Honey for Cough in Children

26 Jul, 2018 | 18:05h | UTC

Honey for cough in children: can it help? – Evidently Cochrane (free)

Original Cochrane Review: Honey for acute cough in children – Cochrane Library (free) AND Summary: Honey for acute cough in children (free)

 


Guideline: Assessment and Management of Polycystic Ovary Syndrome

26 Jul, 2018 | 18:04h | UTC

Recommendations from the international evidence‐based guideline for the assessment and management of polycystic ovary syndrome – Clinical Endocrinology (free)

 


Systematic Review: Blood Pressure Targets in People with Cardiovascular Disease

26 Jul, 2018 | 17:56h | UTC

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease – Cochrane Library (free)

Summary: Blood pressure targets in people with cardiovascular disease – Cochrane Library (free)

“Insufficient evidence to justify lower than standard blood pressure targets in ppl w hypertension + CVD” (via @CochraneHTN see Tweet)

 


Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy

26 Jul, 2018 | 17:44h | UTC

Drugs for treating severe hypertension in pregnancy: A network meta‐analysis and trial sequential analysis of randomized clinical trials – British Journal of Clinical Pharmacology (free)

Commentary: Drugs for treating severe hypertension in pregnancy compared – Wiley, via ScienceDaily (free)

 


Review: Approach to Tinnitus Management

26 Jul, 2018 | 17:43h | UTC

Approach to tinnitus management – Canadian Family Physician (free)

 


Study: Excess Dosing of Hydroxychloroquine

26 Jul, 2018 | 17:37h | UTC

Hydroxychloroquine prescription trends and predictors for excess dosing per recent ophthalmology guidelines – Arthritis Research & Therapy (free)

Commentary: Nearly half of female hydroxychloroquine users in UK excess-dosed – Healio (free registration required)

 


Systematic Review: To Continue Taking or To Stop Taking Antiplatelet Drugs Before Non-Cardiac Surgery

20 Jul, 2018 | 03:31h | UTC

To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (link to abstract – $ for full-text)

Summary: To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults – Cochrane Library (free)

“We found low-certainty evidence that either continuation or discontinuation of antiplatelet therapy before non-cardiac surgery may make little or no difference to mortality, bleeding requiring surgical intervention, or ischaemic events”.

 


Randomized Trial: Subacromial Decompression vs Diagnostic Arthroscopy for Shoulder Impingement

20 Jul, 2018 | 03:28h | UTC

Subacromial decompression versus diagnostic arthroscopy for shoulder impingement: randomised, placebo surgery controlled clinical trial – The BMJ (free)

Commentary: Most common shoulder operation is no more beneficial than placebo surgery – University of Helsinki, via EurekAlert (free)

Related research with similar results: Arthroscopic subacromial decompression for subacromial shoulder pain (free article, editorial and commentaries)

 


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