Family Medicine
Randomized Trial: Treatment Strategies for Untreated Major Depressive Disorder
23 Aug, 2018 | 22:37h | UTC
Randomized Trial: Oral Steroids for Resolution of Otitis Media with Effusion in Children
23 Aug, 2018 | 22:36h | UTCInvited commentary: Helping children with hearing loss from otitis media with effusion – The Lancet (free)
“Short-course oral prednisolone is not an effective treatment for most children aged 2–8 years with persistent otitis media with effusion but is well tolerated—findings from OSTRICH, the first placebo-controlled trial” (via @TheLancet see Tweet)
Report: E-Cigarettes
23 Aug, 2018 | 22:33h | UTCReport: E-Cigarettes – House of Commons Science and Technology Committee (free PDF)
Commentaries: Stop treating e-cigs like conventional cigarettes, MPs tell NHS – OnMedica (free) AND E-cigarettes can be key weapon against smoking, say MPs – BBC (free)
See also: related guidelines, reports and commentaries on e-cigarettes (all free)
Study: Association Between Electronic Cigarette Use and Myocardial Infarction
23 Aug, 2018 | 22:35h | UTCAssociation Between Electronic Cigarette Use and Myocardial Infarction – American Journal of Preventive Medicine (free for a limited period)
Commentary: Risk of heart attacks is double for daily e-cigarette users – University of California – San Francisco, via ScienceDaily (free)
“New analysis shows five-fold risk for people who use both cigarettes and e-cigarettes daily” (from ScienceDaily)
Perspective: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It
23 Aug, 2018 | 22:32h | UTCVitamin D, the Sunshine Supplement, Has Shadowy Money Behind It – The New York Times (10 articles per month are free) (via @CarlosdelRio7 see Tweet)
Related commentaries: Vitamin D Screening and Supplementation in Primary Care: Time to Curb Our Enthusiasm – American Family Physician (free) AND Your vitamin D tests and supplements are probably a waste of money – VOX (free) AND Why Are So Many People Popping Vitamin D? – The New York Times (10 articles per month are free)
Related Guideline: Vitamin D: supplement use in specific population groups – National Institute for Health and Care Excellence (free)
“Only test vitamin D status if someone has symptoms of deficiency or is at very high risk” (from NICE Guideline)
Study: Association of Body Mass Index With Blood Pressure
23 Aug, 2018 | 22:26h | UTCCommentary: As body mass index increases, blood pressure may as well – Yale University (free)
Cohort Studies: Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality
17 Aug, 2018 | 02:35h | UTCSmoking Cessation, Weight Change, Type 2 Diabetes, and Mortality – The New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Weight gain after smoking cessation linked with increased short-term diabetes risk – Harvard T.H. Chan School of Public Health (free) AND Weight gain temporarily hikes diabetes risk when smokers quit – Reuters (free) AND Smokers Are Better Off After They Quit Even if They Gain Weight – Physician’s First Watch (free)
Cohort Study: Risk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes
17 Aug, 2018 | 02:26h | UTCRisk Factors, Mortality, and Cardiovascular Outcomes in Patients with Type 2 Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: In Type 2 Diabetes, Five Risk Factor Targets Keep MI, Stroke, and Death in Check – TCTMD (free) AND How People With Type 2 Diabetes Can Lower Their Risk of Health Problems – TIME (free) AND T2D, Without Other Risks, Not Tied to Excess Mortality – MedPage Today (free registration required)
Review: Overdiagnosis in Primary Care
17 Aug, 2018 | 02:10h | UTCState of the Art Review: Overdiagnosis in primary care: framing the problem and finding solutions – The BMJ (free for two weeks)
Randomized Trial: Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control
17 Aug, 2018 | 02:06h | UTCFixed Low-Dose Triple Combination Antihypertensive Medication vs Usual Care for Blood Pressure Control in Patients With Mild to Moderate Hypertension in Sri Lanka: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Video Summary: Fixed-Dose Combination Pill for Hypertension Treatment in Sri Lanka (free)
Commentaries: Three-in-one pill lowers blood pressure significantly, study says – UPI (free) AND Innovative triple pill significantly lowers blood pressure, study finds – George Institute for Global Health, via EurekAlert (free)
Perspective: The Polypill and the Long Journey to Major Impact
17 Aug, 2018 | 02:05h | UTCRichard Smith: The polypill and the long journey to major impact – The BMJ Opinion (free)
Related Reviews: Strengths and Limitations of Using the Polypill in Cardiovascular Prevention – Current Cardiology Reports (free) AND The polypill approach – An innovative strategy to improve cardiovascular health in Europe – BMC Pharmacology and Toxicology (free)
Book: Diabetes in America, 3rd Edition – National Institutes of Health
17 Aug, 2018 | 02:01h | UTCDiabetes in America, 3rd Edition – National Institutes of Health (free chapters)
News Release: New NIH reference book is one-stop resource for diabetes medical information – National Institutes of Health (free)
Systematic Reviews: Treatments for Women with Gestational Diabetes Mellitus
17 Aug, 2018 | 02:00h | UTCTreatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews – Cochrane Library (free)
Guideline: Screening for Urinary Incontinence in Women
17 Aug, 2018 | 01:52h | UTCCommentaries: WPSI says screen all women annually for urinary incontinence – American College of Physicians, via EurekAlert (free)
Choosing Wisely: Twenty Low-Value Practices in Family Medicine
17 Aug, 2018 | 01:48h | UTCAmerican Academy of Family Physicians: Twenty Things Physicians and Patients Should Question (free)
Commentary: Choosing Wisely: New Practices to Avoid in Family Medicine – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Study: Evaluating Shared Decision Making for Lung Cancer Screening
17 Aug, 2018 | 01:46h | UTCEvaluating Shared Decision Making for Lung Cancer Screening – JAMA Internal Medicine (free for a limited period)
Editorial: Failing Grade for Shared Decision Making for Lung Cancer Screening (free for a limited period)
Author Interview: Evaluating Shared Decision Making for Lung Cancer Screening (free audio)
Commentaries: Doctors may not explain pros, cons of lung cancer screening – Reuters (free) AND Shared Decision-Making Flops for Lung Ca Screening – MedPage Today (free registration required)
Study: Analysis of Clinical Benefit, Harms, and Cost-Effectiveness of Screening Women for Abdominal Aortic Aneurysm
17 Aug, 2018 | 01:48h | UTCCommentaries: Should we screen women for abdominal aortic aneurysm? – The Lancet (free) AND Cost-Effectiveness of Screening Women for AAA – American College of Cardiology (free) AND Women Likely Not Good Targets for AAA Screening, Study Suggests – TCTMD (free)
Analysis: Renaming Low-Risk Conditions Labelled as Cancer
17 Aug, 2018 | 01:39h | UTCRenaming low risk conditions labelled as cancer – The BMJ (free for a limited period)
Commentaries: Is it time to remove the cancer label from low-risk conditions? – The Conversation (free) AND Doctors should avoid saying ‘cancer’ for minor lesions – study – The Guardian (free) Drop ‘cancer’ label to protect patients from over-treatment, researchers say – The Sidney Morning Herald (free)
Cohort Study: Risk Factors Associated With Major Cardiovascular Events 1 Year After Acute Myocardial Infarction
17 Aug, 2018 | 01:41h | UTCCommentaries: Algorithm IDs Patients at Risk of Post-MI Events – MedPage Today (free registration required) AND Risk Model Helps Predict CV Events 1 Year After Acute MI – Medscape (free registration required)
The Multivitamin Industry Rakes in Billions of Dollars. But Science Says We’re Not Getting Healthier
17 Aug, 2018 | 01:38h | UTCRelated Study: Association of Multivitamin and Mineral Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis – Circulation: Cardiovascular Quality and Outcomes (free) AND Editorial: Multivitamins Do Not Reduce Cardiovascular Disease and Mortality and Should Not Be Taken for This Purpose: How Do We Know That? (free)
“Unless you have a clinically identified deficiency, the research tells us there is little reason to consume supplements.”
Perspective: Managing De-implementation in General Practice
16 Aug, 2018 | 23:11h | UTCManaging de-implementation in general practice – Royal Australian College of General Practitioners (free)
Study: Sex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes
16 Aug, 2018 | 23:09h | UTCSex and BMI Alter the Benefits and Risks of Sulfonylureas and Thiazolidinediones in Type 2 Diabetes: A Framework for Evaluating Stratification Using Routine Clinical and Individual Trial Data – Diabetes Care (link to abstract – $ for full-text)
Commentary: Doctors should use gender and body mass to personalise diabetes care, study says – The Irish News (free)
Source: The BMJ Research News ($)
Study: Use of Oximetry to Determine Need for Adenotonsillectomy for Sleep-Disordered Breathing
16 Aug, 2018 | 23:11h | UTCUse of Oximetry to Determine Need for Adenotonsillectomy for Sleep-Disordered Breathing – Pediatrics (link to abstract – $ for full-text)
Commentary: Oximetry Results Help Determine Need for Adenotonsillectomy – Medscape (free registration required)
Things We Do for No Reason: Blood Cultures for Uncomplicated Skin and Soft Tissue Infections in Children
16 Aug, 2018 | 23:08h | UTC
Study: Opioid Prescribing Decreases After Learning of a Patient’s Fatal Overdose
11 Aug, 2018 | 03:25h | UTCOpioid prescribing decreases after learning of a patient’s fatal overdose – Science (free for a limited period)
Commentary: Notification of patient overdose deaths reduces clinician opioid prescriptions – NIH News Releases (free) AND Clinicians were told their patient had died of an overdose. Then opioid prescribing dropped – STAT (free)