Family Medicine
A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure with Preserved Ejection Fraction
31 Aug, 2018 | 03:00h | UTCA Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction – Circulation (free) (via @CircAHA see Tweet with Infographic)
Editorial: H2FPEF Score: At Last, a Properly Validated Diagnostic Algorithm for Heart Failure With Preserved Ejection Fraction (free)
Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus
31 Aug, 2018 | 02:58h | UTCEffects of n−3 Fatty Acid Supplements in Diabetes Mellitus – New England Journal of Medicine (free for a limited period)
Commentaries: Fish oils do not prevent heart attack or strokes in people with diabetes – ESC News Releases (free) AND Omega-3 Fatty Acids Fail to Reduce CVD Events in Diabetic Patients: ASCEND – TCTMD (free)
Related Cochrane Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (link to abstract and commentaries)
Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free study and commentary)
Guideline Synopsis: Diagnosis and Treatment of Clostridium difficile Infection
31 Aug, 2018 | 02:51h | UTCDiagnosis and Treatment of Clostridium difficile Infection – JAMA (free for a limited period) (via @ABsteward and @Abraham_RMI)
Original Guideline: Clinical Practice Guidelines for Clostridium difficileInfection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) – Clinical Infectious Diseases (free)
CHEST Guideline: Antithrombotic Therapy for Atrial Fibrillation
31 Aug, 2018 | 02:56h | UTCAntithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report (free PDF)
News Release: The American College of Chest Physicians updates their antithrombotic therapy guidelines for patients with atrial fibrillation (free)
Evidence Review: Optimal Blood Pressure Target in Diabetic and Nondiabetic Hypertensive Patients
31 Aug, 2018 | 02:44h | UTCSee counterpoint suggesting lower BP targets: Sprinting Toward the Optimal Blood Pressure Target for Hypertensive Patients – Circulation Research (free)
“We have reviewed the randomized trial evidence in favor of a target blood pressure (BP) around 130/80 mm Hg in hypertensive patients with and without diabetes mellitus”
Study: Vitamin D Not Linked to Fracture Risk
31 Aug, 2018 | 02:43h | UTCCommentaries: Vitamin D: a pseudo-vitamin for a pseudo-disease – The Conversation (free) AND Fracture risk not linked to low vitamin D or calcium levels – OnMedica (free)
Related: Vitamin D, the Sunshine Supplement, Has Shadowy Money Behind It (free commentaries and NICE Guideline)
New CDC Analysis Shows Steep and Sustained Increases in STDs in Recent Years
31 Aug, 2018 | 02:37h | UTC2018 STD Prevention Conference – Centers for Disease Control and Prevention (free)
Press Release: New CDC analysis shows steep and sustained increases in STDs in recent years (free)
Commentaries: 5 reasons why 3 STDs are roaring back in America – VOX (free) AND Rates of three STDs in US reach record high, CDC says – CNN (free) AND Record High Number Of STD Infections In U.S., As Prevention Funding Declines – NPR (free) AND STD cases in U.S. hit record highs as officials warn about resistant gonorrhea – STAT (free) AND US sees record STD cases, rising gonorrhea resistance – CIDRAP (free)
Guideline: Management of Hip and Knee Osteoarthritis
31 Aug, 2018 | 02:31h | UTCNews Release: Updated osteoarthritis guideline designed to reduce unnecessary imaging and surgery (free)
Commentary: Australia hopes to reduce unnecessary imaging, surgery with updated osteoarthritis guidelines – Health Imaging (free)
““The Guideline for the management of knee and hip osteoarthritis,” offer up exercise and weight loss as a first line defense, and warn against costly treatments using glucosamine, opioids and arthroscopic surgery, said David Hunter, co-chair of the RACGP group responsible for the update.” (from Health Imaging)
Zackary Berger’s journal reviews, 28 August 2018
31 Aug, 2018 | 02:02h | UTCZackary Berger’s journal reviews, 28 August 2018 – The BMJ Opinion (free)
Randomized Trial: Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients
31 Aug, 2018 | 01:58h | UTCCardiovascular Safety of Lorcaserin in Overweight or Obese Patients – New England Journal of Medicine (free for a limited period)
Editorial: Lorcaserin — Elixir or Liability? (free for a limited period)
Commentaries: CAMELLIA-TIMI 61: Weight Loss Drug Lorcaserin Did Not Increase CV Events – American College of Cardiology (free) AND Weight-Loss Drug Lorcaserin Clears Cardiovascular Safety Hurdle: CAMELLIA-TIMI 61 – TCTMD (free) AND Weight loss drug lorcaserin found safe in large study – Reuters (free)
Guiding Principles for the Care of People with or at Risk for Diabetes
31 Aug, 2018 | 02:00h | UTCCommentaries: NIDDK Updates ‘Guiding Principles’ for Diabetes, Prediabetes – Medscape (free registration required) AND NDEP revises principles for managing diabetes, prediabetes – Cardiovascular Business (free)
Related Book: Diabetes in America, 3rd Edition – National Institutes of Health (free reference book, just released)
Cohort Study: No Survival Benefit with Beta-Blockers Beyond 1 Year Post-MI in Stable CAD
31 Aug, 2018 | 01:55h | UTCCLARIFY: No Survival Benefit With Beta-Blockers Beyond 1 Year Post-MI in Stable CAD – TCTMD (free)
Related Study: B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction (free study and commentary)
“The problem, said Sorbets, is that there have never been large randomized trials to test the prognostic effects of beta-blockers in this patient group and instead, recommendations have been drawn from meta-analyses using data extracted from the acute MI setting or from observational studies.”
Study: Emergency Department Visits for Adverse Drug Events from Antibiotics in Children
31 Aug, 2018 | 01:44h | UTCCommentaries: Antibiotic side effects send 70,000 children to ER each year, study says – UPI (free) AND Antibiotic side-effects in kids lead to nearly 70,000 ER visits in the US each year – Pediatric Infectious Diseases Society, via ScienceDaily (free)
Systematic Review: Antibiotics for Prolonged Wet Cough in Children
31 Aug, 2018 | 01:40h | UTCAntibiotics for prolonged wet cough in children – Cochrane Library (link to abstract and plain language summary – $ for full-text)
Commentary: Antibiotics for pediatric chronic wet cough: Cochrane review – Univadis (free registration required)
Perspective: Adolescents’ Use of “Pod Mod” E-Cigarettes — Urgent Concerns
23 Aug, 2018 | 23:51h | UTCAdolescents’ Use of “Pod Mod” E-Cigarettes — Urgent Concerns – New England Journal of Medicine (free)
NICE Draft Guidance: Antibiotics Should Not Be Issued as First Line of Treatment for a Cough
23 Aug, 2018 | 23:52h | UTCCommentaries: Promote honey rather than antibiotics for coughs, doctors told – The Guardian (free) AND Use honey first for a cough, new guidelines say – BBC (free)
Related: Honey for acute cough in children – Cochrane Library (free systematic review and commentary)
Study: Alcohol Use and Burden for 195 Countries and Territories
23 Aug, 2018 | 23:53h | UTCCommentaries: No level of alcohol consumption improves health – The Lancet (free) AND No amount of alcohol is good for your overall health, global study says – CNN (free) AND New scientific study: no safe level of alcohol – Institute for Health Metrics and Evaluation (free)
“Alcohol was responsible for nearly 3 million deaths in 2016, the study says. It was the leading risk factor for disease and premature death in men and women between the ages of 15 and 49 worldwide in 2016, accounting for nearly one in 10 deaths.” (from @cnni see Tweet)
Systematic Review: Glucocorticoids for Croup in Children
23 Aug, 2018 | 23:46h | UTCGlucocorticoids for croup in children – Cochrane Library (free for a limited period)
Summary: Glucocorticoids for croup in children – Cochrane Library (free)
Commentary: Glucocorticoid Therapy Examined in Pediatric Patients With Croup – MPR (free)
Study: Asthma and COPD Overlap in Women
23 Aug, 2018 | 23:42h | UTCAsthma and COPD Overlap in Women: Incidence and Risk Factors – Annals of the American Thoracic Society (link to abstract – $ for full-text)
Commentaries: More than 40 percent of women with asthma may develop COPD, but risk may be reduced – Annals of Thoracic Society (free) AND Four in 10 women with asthma may develop COPD – Reuters (free) AND Four in 10 women with asthma may develop COPD – OnMedica (free)
Meta-Analysis: Sport Specialization and Risk of Overuse Injuries
23 Aug, 2018 | 23:43h | UTCSport Specialization and Risk of Overuse Injuries: A Systematic Review With Meta-analysis – Pediatrics (link to abstract – $ for full-text)
Commentary: Sport specialization tied to injuries in kids and teens – Reuters (free)
USPSTF Statement: Screening for Cervical Cancer
23 Aug, 2018 | 23:27h | UTCScreening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)
Related articles: Screening for Cervical Cancer With High-Risk Human Papillomavirus Testing: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA (free) AND Screening for Cervical Cancer in Primary Care: A Decision Analysis for the US Preventive Services Task Force – JAMA (free)
Editorials: Screening for Cervical Cancer: New Tools and New Opportunities (free for a limited period) AND Cervical Cancer Screening—Moving From the Value of Evidence to the Evidence of Value (free for a limited period)
Author Interview: USPSTF Recommendation: Screening for Cervical Cancer (free)
Final Update Summary: Cervical Cancer: Screening – US Preventive Service Task Force (free)
Commentaries: Cervical cancer screening without Pap test OK for some women – Reuters (free) AND For Cervical Cancer Screening, Women Over 30 Can Now Choose The HPV Test Only – NPR (free) AND Annual Pap Test a ‘Thing of the Past?’ – Florida Atlantic University (free)
Position Statement: Management of Heart Failure in India
23 Aug, 2018 | 23:26h | UTCCSI position statement on management of heart failure in India – Indian Heart Journal (free)
Study: Anticonvulsant and the Risk for Opioid-Related Death
23 Aug, 2018 | 23:21h | UTCPregabalin and the Risk for Opioid-Related Death: A Nested Case–Control Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Pregabalin may increase the risk of death when coprescribed with opioids – 2 Minute Medicine (free) AND Pregabalin Linked To Increased Risk for Opioid-Related Deaths – MedicalResearch.com (free) AND Anticonvulsant With Opioids Tied To Higher Mortality – MedPage Today (free registration required)
Cohort Study: Long-Term Association of LDL Cholesterol With Cardiovascular Mortality in Low-Risk Individuals
23 Aug, 2018 | 23:22h | UTCCommentaries: ‘Bad’ cholesterol can be deadly in otherwise healthy people – AHA News (free) AND LDL >160 Tied to Increased Mortality in Low-Risk Patients – Physician’s First Watch (free) AND Study: Elevated LDL, non-HDL increase CVD mortality risk in young, healthy individuals – Cardiovascular Business (free) AND Moderate ‘bad cholesterol’ levels tied to early death for healthy people – Reuters (free)
AAP Report: Want Creative, Curious, Healthier Children with 21st Century Skills? Let Them Play
23 Aug, 2018 | 23:19h | UTCClinical Report: The Power of Play: A Pediatric Role in Enhancing Development in Young Children – Pediatrics (free)
News Release: Want Creative, Curious, Healthier Children with 21st Century Skills? Let Them Play – American Academy of Pediatrics (free)
Commentary: It’s come to this: A checkup with the pediatrician may soon include a prescription for play – Los Angeles Times (free) AND Let Kids Play – The New York Times (10 articles per month are free) AND AAP Report Highlights Importance of Children’s Play for Development – Journal Watch (free)


