Family Medicine
FDA Safety Alert: Serious Incidents Related to Certain Prescription Insomnia Medicines
2 May, 2019 | 04:34h | UTCFor Consumers: Taking Z-drugs for Insomnia? Know the Risks – U.S. Food & Drug Administration (free)
Commentaries: Drug Agency Calls for Strong Warning Labels on Popular Sleep Aids – The New York Times (10 articles per month are free) AND FDA Requires Stronger Warnings for Common Insomnia Medications – Psychiatric News Alert (free)
Key Points From the 2019 ACC/AHA Guidelines on the Primary Prevention of Cardiovascular Disease
2 May, 2019 | 04:37h | UTCOriginal Guideline: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free guideline and resources)
Review: Chronic Constipation
2 May, 2019 | 04:31h | UTCChronic Constipation – Mayo Clinic Proceedings (free)
Related: Indian Consensus on Chronic Constipation in Adults (free guidelines and reviews on the subject)
Alex Nowbar’s research reviews – 30 April 2019
1 May, 2019 | 07:02h | UTCAlex Nowbar’s research reviews, 30 April 2019 – The BMJ Opinion (free)
Study: Fluoroquinolones Associated with Peripheral Neuropathy
30 Apr, 2019 | 02:40h | UTCAssociation Between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy – JAMA Neurology (free for a limited period)
Editorial: On the Association Between Fluoroquinolones and Neuropathy (free)
Related: Committee Recommends New Restrictions on the use of Fluoroquinolones (free report and commentaries)
Study: Benefits of Statins Questioned for Primary Prevention of Cardiovascular Disease
30 Apr, 2019 | 02:35h | UTCCommentary: NNT with statins is 400 for lower risk eligible patients, researchers estimate – Pulse (free)
2019 Chinese Guideline for the Management of Hypertension in the Elderly
28 Apr, 2019 | 13:35h | UTC
Contemporary Concise Review 2018: Asthma and COPD
28 Apr, 2019 | 13:27h | UTCContemporary Concise Review 2018: Asthma and chronic obstructive pulmonary disease – Respirology (free)
Cardiovascular Comorbidities in COPD—Current Considerations for Clinical Practice
28 Apr, 2019 | 13:29h | UTC
Meta-Analysis: Proton Pump Inhibitors may Increase the Risk of Hip Fractures
28 Apr, 2019 | 13:25h | UTCMedication to reduce stomach acid may increase risk of hip fractures – NIHR Signal (free)
Original Article: Proton pump inhibitors and risk of hip fracture: a meta-analysis of observational studies – Osteoporosis International (link to abstract – $ for full-text)
Clinical Guideline for Urinary Stone Disease
26 Apr, 2019 | 02:09h | UTCRelated: NICE Guideline – Renal and Ureteric Stones: Assessment and Management (free guidelines)
Systematic Review: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention
26 Apr, 2019 | 02:05h | UTCSee also: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review – Agency for Healthcare Research and Quality (free) AND Full Report (free PDF) AND Evidence Summary (free PDF)
JAMA Guideline Synopsis: Colorectal Cancer Screening
26 Apr, 2019 | 01:55h | UTCColorectal Cancer Screening – JAMA (free for a limited period)
Related: Colorectal Cancer Screening for Average‐risk Adults (guidelines from other organizations)
Sitting Time, Physical Activity, and Risk of Mortality in Adults
26 Apr, 2019 | 01:54h | UTCCommentaries: How much do sedentary people really need to move? It’s less than you think – The Conversation (free) AND Physical Activity May Offset Mortality Risk Caused by Too Much Sitting – American College of Cardiology (free) AND Sitting Kills, in a Dose-Response Fashion, but Regular Physical Activity Attenuates Risks – TCTMD (free) AND Computers, not TV, are to blame for increase in US sitting time, study says – CNN (free)
USPSTF Draft Statement: Screening for Asymptomatic Bacteriuria in Adults
24 Apr, 2019 | 06:34h | UTCDraft Recommendation Statement: Asymptomatic Bacteriuria in Adults: Screening – U.S. Preventive Services Task Force (free)
Commentary: USPSTF Eases Recommendation for Asymptomatic Bacteriuria Screening in Pregnant Women – NEJM Journal Watch (free)
Meta-Analysis: Effects of Intensive Blood Pressure Lowering in Patients with Type 2 Diabetes
25 Apr, 2019 | 02:02h | UTC
Study: Long-Term Weight Loss with Metformin
24 Apr, 2019 | 06:24h | UTCLong-Term Weight Loss with Metformin or Lifestyle Intervention in the Diabetes Prevention Program Outcomes Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Metformin may help patients maintain weight loss long-term – American College of Physicians (free) AND Metformin may help people at high diabetes risk to maintain weight loss – Medicine Matters (free) AND Metformin may help patients maintain long-term weight loss – 2 Minute Medicine (free)
Clinical Update: Metformin in 2019
23 Apr, 2019 | 01:50h | UTCMetformin in 2019 – JAMA (free for a limited period)
Perspective: Shared Decision Making and the Importance of Time
22 Apr, 2019 | 02:18h | UTCShared Decision Making and the Importance of Time – JAMA (free for a limited period)
Review: Treatment of Medication Overuse Headache
21 Apr, 2019 | 21:10h | UTCTreatment of medication overuse headache—A review – Acta Neurologica Scandinavica (free)
Review: Obstructive Sleep Apnea and Comorbidities
20 Apr, 2019 | 13:42h | UTCRelated: Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy (free reviews)
Cochrane Review: Nicotine Replacement for Smoking Cessation More Successful in Combination Form
19 Apr, 2019 | 08:42h | UTCDifferent doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation – Cochrane Library (free)
Commentaries: Nicotine replacement: when quitting cigarettes, consider using more nicotine, not less – The Conversation (free) AND Nicotine replacement therapy: new evidence on help to quit smoking – Evidently Cochrane (free) AND Nicotine replacement therapy more successful in combination form – Nuffield Department of Primary Care Health Sciences (free)
Related Commentary on Twitter
Featured Cochrane Review: Different doses, durations and modes of delivery of #nicotine replacement therapy for #smoking cessation from @CochraneTAG – Read comments from lead author https://t.co/WBvMA74iaK and the full review https://t.co/QFLx9Wb9Xc pic.twitter.com/tk2J6WRT3Z
— Cochrane (@cochranecollab) April 18, 2019
Meta-Analysis: Accuracy of Patient Health Questionnaire-9 (PHQ-9) for Screening to Detect Major Depression
19 Apr, 2019 | 08:39h | UTCCommentaries: The accuracy of the Patient Health Questionnaire-9 for detecting major depression – The BMJ Opinion (free) AND Screening tools for depression offer value when combined with an informed shared decision process – The BMJ Opinion (free) AND Using the Patient Health Questionnaire-9 to Screen for Major Depression – NEJM Journal Watch (free)
Hypertension in Pregnancy: Pathophysiology and Treatment
19 Apr, 2019 | 08:33h | UTCHypertension in pregnancy: Pathophysiology and treatment – SAGE Open Medicine (free)
Related Guidelines: WHO recommendations: Drug treatment for severe hypertension in pregnancy – World Health Organization (free) AND Hypertension Canada’s 2018 Guidelines for the Management of Hypertension in Pregnancy (free)
Related Meta-Analysis: Drugs for Treating Severe Hypertension in Pregnancy (free study and commentary)
Related Review: State-of-the-Art Diagnosis and Treatment of Hypertension in Pregnancy – Mayo Clinic Proceedings (free)
Another Observational Study Showing Association of Statin Use with Risk of New‐Onset Diabetes Mellitus
19 Apr, 2019 | 08:25h | UTCEditorial: Perils of Observational Data Analyses (free)
Commentary: Statins for primary prevention: do benefits outweigh DM risk? – Univadis (free registration required)
Related: Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes (free study and commentaries)