Family Medicine
Perspective: The Dangers of Ignoring the Beers Criteria—The Prescribing Cascade
15 May, 2019 | 06:43h | UTCThe Dangers of Ignoring the Beers Criteria—The Prescribing Cascade – JAMA Internal Medicine (free for a limited period)
Original Article: AGS 2019 Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults (link to abstract – $ for full-text)
Study: Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies
14 May, 2019 | 05:58h | UTCEstimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)
Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)
“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”
Related Commentary on Twitter
Cytology every 3 years and low-cost #hrHPV testing every 5 years are both reasonable cervical-cancer screening options for women ages 30-65. https://t.co/yRCzmKGxP9
— JAMA Internal Medicine (@JAMAInternalMed) May 13, 2019
Meta-Analysis: Frequency of Intracranial Hemorrhage with Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease
14 May, 2019 | 05:23h | UTCFrequency of Intracranial Hemorrhage With Low-Dose Aspirin in Individuals Without Symptomatic Cardiovascular Disease: A Systematic Review and Meta-analysis – JAMA Neurology (free for a limited period)
Commentaries: Low-dose aspirin linked to bleeding in the skull, new report says – CNN (free) AND Study links low-dose aspirin to bleeding inside the skull – UPI (free)
Related Commentary on Twitter
Low-dose #aspirin was associated with an overall increased risk of intracranial hemorrhage among people without symptomatic #cardiovasculardisease https://t.co/FTkbZpvDr8
— JAMA Neurology (@JAMANeuro) May 14, 2019
Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank
14 May, 2019 | 05:05h | UTC
Study: Kissing May be an Important and Neglected Risk Factor for Oropharyngeal Gonorrhea
13 May, 2019 | 01:27h | UTCCommentary: Deep kissing – a neglected route for throat gonorrhea – OnMedica (free) AND Deep Kissing Might Spread Oropharyngeal Gonorrhea in MSM – NEJM Journal Watch (free)
Related Commentary on Twitter
Deep (tongue) kissing may be an important and neglected route for passing on throat (oropharyngeal) #gonorrhoea among gay and bisexual men ➡️ https://t.co/ncRmyfq8GE @EricPFChow @MSHCResearch @TheDohertyInst pic.twitter.com/Ls8bicwWh4
— STI_BMJ (@STI_BMJ) May 10, 2019
Cohort Study: High Intakes of Vitamins B6 and B12 From Food and Supplements are Associated with Increased Risk of Hip Fracture
13 May, 2019 | 01:25h | UTC
Systematic Review: Impact of Non-drug Therapies on Asthma Control
13 May, 2019 | 01:05h | UTC
Abnormal Uterine Bleeding in Reproductive-Age Women
11 May, 2019 | 15:49h | UTCAbnormal Uterine Bleeding in Reproductive-Age Women – JAMA (free for a limited period)
Study: Late-onset Type 1 Diabetes Commonly Treated as Type 2 Diabetes
10 May, 2019 | 05:03h | UTCCommentary: Patients with late-onset type 1 diabetes commonly treated as having type 2 diabetes – ACP Diabetes (free)
Randomized Trial: Azithromycin During Acute COPD Exacerbations Requiring Hospitalization
9 May, 2019 | 07:57h | UTCAzithromycin during Acute COPD Exacerbations Requiring Hospitalization (BACE): a Multicentre, Randomized, Double-blind, Placebo-controlled Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
Commentaries: Azithromycin appears to reduce treatment failure in severe, acute COPD exacerbations – American Thoracic Society (free) AND Azithromycin May Reduce Treatment Failure in Patients With Acute Exacerbation of COPD – AJMC (free)
Meta-Analysis: Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes
8 May, 2019 | 06:57h | UTCAssociation of Gestational Weight Gain With Adverse Maternal and Infant Outcomes – JAMA (free for a limited period)
Editorial: Prepregnancy Body Mass Index, Weight Gain During Pregnancy, and Health Outcomes (free for a limited period)
“Optimal gestational weight gain ranges were 14.0 kg to less than 16.0 kg for women categorized as underweight; 10.0 kg to less than 18.0 kg for normal weight; 2.0 kg to less than 16.0 kg for overweight; 2.0 kg to less than 6.0 kg for obesity grade 1; weight loss or gain of 0 kg to less than 4.0 kg for obesity grade 2; and weight gain of 0 kg to less than 6.0 kg for obesity grade 3.”
Approaches to Asthma Diagnosis in Children and Adults
8 May, 2019 | 02:03h | UTCApproaches to Asthma Diagnosis in Children and Adults – Frontiers in Pediatrics (free)
The Management of Hypertension in 2018: What Should the Targets Be?
8 May, 2019 | 01:59h | UTCThe Management of Hypertension in 2018: What Should the Targets Be? – Current Hypertension Reports (free)
Study: Fournier Gangrene Associated with SGLT2 Inhibitors
7 May, 2019 | 01:13h | UTCFournier Gangrene Associated With Sodium–Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: SGLT2 inhibitors associated with rare, life-threatening necrotizing genital infections – ACP Internist (free) AND Potentiall fatal infection of genitals identified as rare side effect of SGLT2 Inhibitors – American College of Physicians (free) AND Postmarketing data support Fournier gangrene link with SGLT2 inhibitors – Medicine Matters (free)
Related: SGLT2 inhibitors: reports of Fournier’s gangrene (necrotising fasciitis of the genitalia or perineum) – GOV.UK (free)
Guideline Synopsis: Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period
7 May, 2019 | 01:06h | UTCDiagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period – JAMA (free for a limited period)
Original Article: 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum (free)
Aspirin for Primary Prevention: Is This the End of the Road?
6 May, 2019 | 22:43h | UTCAspirin for primary prevention: Is this the end of the Road? – Indian Heart Journal (free)
Related Randomized Trials: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (free) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (free)
Related Meta-Analysis: Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries) AND Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events (free)
Meta-analysis: Comparison of the Effects of GLP1 Receptor Agonists and SGLT2 Inhibitors for Prevention of Cardiovascular and Renal Outcomes in Type 2 Diabetes
6 May, 2019 | 22:27h | UTC
Study: Effects of Intensive Blood Pressure Therapy for Type 2 Diabetes
6 May, 2019 | 22:23h | UTCEffects of Blood Pressure Lowering on Clinical Outcomes According to Baseline Blood Pressure and Cardiovascular Risk in Patients With Type 2 Diabetes Mellitus: The ADVANCE Trial – Hypertension (link to abstract – $ for full-text)
Commentaries: Intensive blood pressure therapy for type 2 diabetes reduces cardiovascular risk – UPI (free) AND ADVANCE analysis fuels debate on BP targets in type 2 diabetes – Medwire News (free) AND Analysis Supports Aiming for Lower BP in Patients With Diabetes, Hypertension – TCTMD (free)
NICE Guideline: Management of Ulcerative Colitis
5 May, 2019 | 22:12h | UTCUlcerative colitis: management – National Institute for Health and Care Excellence (free)
Related Guidelines: ACG Clinical Guideline: Ulcerative Colitis in Adults – American Journal of Gastroenterology (free) AND AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology (free) AND Updated S3-Guideline Ulcerative Colitis. German Society for Digestive and Metabolic Diseases (DGVS) – Zeitschrift für Gastroenterologie (free) AND Management of Paediatric Ulcerative Colitis (free)
NICE Guideline: Management of Crohn’s disease
5 May, 2019 | 22:10h | UTCCrohn’s disease: management – National Institute for Health and Care Excellence (free)
Related: ACG Clinical Guideline: Management of Crohn’s Disease in Adults – The American Journal of Gastroenterology (free)
ACOG Practice Advisory: Management of Pregnant and Reproductive-Aged Women during a Measles Outbreak
5 May, 2019 | 22:05h | UTCSee also: Measles & the MMR Vaccine: Recommendations Around Pregnancy, Including the Periconception and Postpartum Periods – University of Washington (free PDF)
Commentary: ACOG Practice Advisory: patient management during a measles outbreak – Univadis (free registration required)
Should Adults Get a Measles Booster Shot?
5 May, 2019 | 22:03h | UTCShould Adults Get a Measles Booster Shot? – The New York Times (10 articles per month are free)
See also: Measles Shots Aren’t Just For Kids: Many Adults Could Use A Booster Too – NPR (free) AND HHS, CDC Address Ongoing Measles Outbreaks – AAFP (free) AND Measles, Mumps, and Rubella (MMR) Vaccination: What Everyone Should Know – CDC (free)
AUA/CUA/SUFU Guideline: Recurrent Uncomplicated Urinary Tract Infections in Women
3 May, 2019 | 07:43h | UTCRecurrent Uncomplicated Urinary Tract Infections in Women: AUA/CUA/SUFU Guideline (2019)
Commentary: Recommendations for the Evaluation, Management of Recurrent UTI in Women Released – MPR (free)
Undetectable = Untransmittable: Risk of HIV Transmission in Serodifferent Gay Couples
3 May, 2019 | 07:38h | UTCCommentary: Successful treatment of HIV eliminates sexual transmission – The Lancet (free)
Related: Systematic Review: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed (free study and commentaries) AND UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free)
Study: Basal Insulin Doses >0.5 IU/kg/d Have Diminishing Additional Impact on Improving Glycemic Measures
2 May, 2019 | 12:53h | UTCCommentary: What’s the maximum effective basal insulin dose in T2D? – Univadis (free registration required)