Family Medicine
Meta-analysis: Omega-3 Fats Not Beneficial for Diabetes Prevention or Treatment
22 Aug, 2019 | 10:53h | UTCCommentaries: The role of nutrition in disease prevention—how we can find better answers? – The BMJ Opinion (free) AND Omega-3 fats have little or no effect on type 2 diabetes – BMJ (free) AND Lack of omega-3 effect on type 2 diabetes confirmed – Medicine Matters (free) AND Fish oil pills ‘no benefit’ for type 2 diabetes – BBC (free)
Related Randomized Trial: Effects of n−3 Fatty Acid Supplements in Diabetes Mellitus (free study and commentaries)
USPSTF Statement on BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing
21 Aug, 2019 | 08:42h | UTCEditorials: Broadening Criteria for BRCA1/2 Evaluation: Placing the USPSTF Recommendation in Context – JAMA (free for a limited period) AND Hereditary Cancer Evaluation in 2019—a Rapidly Evolving Landscape – JAMA Oncology (free for a limited period) AND US Preventive Services Task Force Breast Cancer Recommendation Statement on Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer – JAMA Surgery (free for a limited period) AND USPSTF Recommendations for BRCA1 and BRCA2Testing in the Context of a Transformative National Cancer Control Plan – JAMA Network Open (free)
Author Interview: USPSTF Recommendation: Assessment, Counseling, and Testing for BRCA-Related Cancer (free audio)
Commentaries: More women should be assessed for BRCA mutations, new recommendations say – CNN (free) AND Expert panel updates advice on BRCA cancer gene screening – Reuters (free)
Meta-analysis: Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth
21 Aug, 2019 | 08:38h | UTCAssociation of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Editorial: Thyroid Function Test Abnormalities During Pregnancy (free)
Study: Billions Could be Saved if Older Generics Were Prescribed
21 Aug, 2019 | 08:32h | UTCCommentary: Prescribing older generics could’ve saved Medicare $17.7B, study finds – Becker’s Hospital Review (free)
Related Study: Potential Savings from Generic Substitution and Therapeutic Interchange of ACE Inhibitors and Angiotensin-II-Receptor Blockers (no abstract – $ for full-text)
Meta-Analysis: Maternal Influenza Vaccination is Not Associated with Harmful Effects on Birth Outcomes
20 Aug, 2019 | 08:24h | UTCRelated Research: Cohort Study: Flu Vaccine in Pregnancy Safe for Children and Mothers (free)
Related ACOG Guideline: Influenza Vaccination During Pregnancy (free)
“maternal influenza vaccination is not associated with harmful effects on birth outcomes. The beneficial effects reported from previous studies on preterm birth, low birth weight, and fetal death could not be confirmed.”
Meta-Analysis: Global Incidence of Frailty and Prefrailty Among Community-Dwelling Older Adults
20 Aug, 2019 | 08:20h | UTCCommentaries: The Dynamics of Frailty Among Older Adults – JAMA Network Open (free) AND Frailty is a medical condition, not an inevitable result of aging – Monash University (free)
Related: Best practice guidelines for the management of frailty: a British Geriatrics Society, Age UK and Royal College of General Practitioners report – Age and Ageing (free) AND A Review of Frailty Syndrome and Its Physical, Cognitive and Emotional Domains in the Elderly – Geriatrics (free) AND Frailty: Identifying elderly patients at high risk of poor outcomes – Canadian Family Physician (free)
Consensus Recommendations: Pregnancy After Bariatric Surgery
18 Aug, 2019 | 22:08h | UTCRelated: Pregnancy after bariatric surgery and adverse perinatal outcomes: A systematic review and meta-analysis – PLOS Medicine (free)
[Abstract Only] Meta-analysis: Association Between Electronic Cigarette Use and Marijuana Use Among Adolescents and Young Adults
18 Aug, 2019 | 21:54h | UTCAssociation Between Electronic Cigarette Use and Marijuana Use Among Adolescents and Young Adults: A Systematic Review and Meta-analysis – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: Youth Who Use E-Cigarettes May Be More Likely to Use Marijuana, Study Finds – Psychiatric News Alert (free) AND Teens who vape three times more likely to use marijuana – UPI (free) AND Vaping linked to marijuana use in young people, research says – CNN (free)
Randomized Trial: Bismuth Subsalicylate Reduces Antibiotic Use Among Adult Outpatients With Diarrhea
18 Aug, 2019 | 21:59h | UTC
Meta-Analysis: Association Between Vitamin D Supplementation and Mortality
16 Aug, 2019 | 07:59h | UTCRelated: Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention (link to abstract and commentary) AND NICE Guideline: Vitamin D Supplementation (free)
Vitamin D supplementation was not associated with all-cause mortality, cardiovascular mortality, or non-cancer, non-cardiovascular mortality. However, Vitamin D supplementation statistically significantly reduced the risk of cancer death by 16%.
Related Commentary on Twitter
Vitamin D supplementation alone was not associated with all cause mortality in adults compared with placebo or no treatment. However, it was associated with a reduced risk of cancer mortality by 16%, finds #BMJResearch https://t.co/jc4Tdxl6Bb
— The BMJ (@bmj_latest) August 12, 2019
Essential Tremor: Diagnosis and Management
16 Aug, 2019 | 07:55h | UTCEssential tremor: diagnosis and management – The BMJ (free for a limited period)
CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults
16 Aug, 2019 | 07:53h | UTCCommentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)
[Abstract Only] Study: Diabetes Being Overtreated in Many Vulnerable Clinically Complex Adults
16 Aug, 2019 | 07:50h | UTCSevere Hypoglycemia Attributable to Intensive Glucose-Lowering Therapy Among US Adults With Diabetes – Mayo Clinic Proceedings (link to abstract – $ for full-text)
Commentary: Too Much of a Good Thing Can Be Dangerous, Finds Researchers Investigating Hypoglycemia – Mayo Clinic (free)
Related Studies: Overtreatment and Deintensification of Diabetic Therapy among Medicare Beneficiaries – Journal of General Internal Medicine (free) AND Rates of Deintensification of Blood Pressure and Glycemic Medication Treatment Based on Levels of Control and Life Expectancy in Older Patients With Diabetes Mellitus – JAMA Internal Medicine (free)
AAN Guidelines for the Pharmacologic Prevention and Treatment of Migraine in Children and Adolescents
15 Aug, 2019 | 10:27h | UTCSee also: Practice guideline update summary: Acute treatment of migraine in children and adolescents – Neurology (free PDF)
Commentaries: AAN issues guidelines for treatment of migraine in children and teens – American Academy of Neurology (free) AND Guidelines Updated on Preventing and Treating Migraine in Children and Teens – NEJM Journal Watch (free)
Study: High Gluten Intake During Childhood May Increase the Risk of Celiac Disease in Genetically Predisposed Children
15 Aug, 2019 | 08:12h | UTCAssociation of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk – JAMA (free for a limited period)
Editorial: Gluten and Celiac Disease Risk: Is It Just a Matter of Quantity? (free for a limited period)
Commentaries: Association between coeliac disease risk and gluten intake confirmed – Lund University (free) High Gluten Diet Adds to Risk of Celiac Disease In Genetically Predisposed Children – MedicalResearch.com (free) AND Eating more gluten early in life is tied to children’s higher risk of celiac disease, a study says – CNN (free)
[Abstract Only] Randomized Trial: Ibuprofen Administered at Doses of 400, 600, and 800 mg Had Similar Analgesic Efficacy in Acute Pain.
15 Aug, 2019 | 06:58h | UTCComparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary: Don’t Use More Than 400 mg of Ibuprofen for Pain Control – NEJM Journal Watch (free for a limited period)
Related Commentary on Twitter
Hot off the Press: Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial https://t.co/Wq6PCgRaUw @painfreeED pic.twitter.com/7PLtD3IJ7I
— AnnalsofEM (@AnnalsofEM) August 13, 2019
Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia
14 Aug, 2019 | 10:33h | UTCAssociation of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia – JAMA (free for a limited period)
Related Research: Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions – JAMA (free for a limited period)
Editorial: Blood Pressure, Brain Volume and White Matter Hyperintensities, and Dementia Risk (free for a limited period)
Video Summary: Hypertension and Dementia (free)
Commentary: Expert reaction to two studies looking at blood pressure and dementia – Science Media Centre (free)
[Abstract Only] Cohort Study: Individuals with 1 or 2 Small Adenomas at Baseline Screening Colonoscopy Have a Similar Risk of Advanced Neoplasia over 10 years as Individuals with no Baseline Adenomas
14 Aug, 2019 | 08:34h | UTCBaseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text)
Related Study: Colonoscopy Adenoma Findings and Long-term Colorectal Cancer Incidence (free study, commentaries and guidelines on the subject)
Source: NEJM Journal Watch ($)
Update on the Contraceptive Contraindications
14 Aug, 2019 | 08:32h | UTCRelated Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)
USPSTF Draft Recommendation Statement: Screen for Illicit Drug Use in Adults Age 18 Years or Older
14 Aug, 2019 | 08:24h | UTCCommentaries: For the first time, U.S. panel recommends screening adults for illicit drug use – STAT (free) AND Screen All Adult Patients for Drug Abuse, National Panel Urges – The New York Times (10 articles per month are free) AND
[Abstract Only] Study: The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity
14 Aug, 2019 | 08:16h | UTCRoles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data – The Lancet Child & Adolescent Health (link to abstract – $ for full-text)
Commentaries: Social media use may harm teens’ mental health by disrupting positive activities, study says – CNN (free) AND Social-media use ‘disrupting teen sleep and exercise’ – BBC (free) Expert reaction to study on social media use and the role of cyberbullying, sleep and physical activity in the wellbeing in young people – Science Media Centre (free) AND Social Media’s Ill Effects in Teen Girls: 3 Factors Play Large Role – NEJM Journal Watch (free)
Related Commentary on Twitter
New study suggests that #SocialMedia itself doesn't cause harm to #adolescents, but #MentalHealth harms related to very frequent use in girls might be due to exposure to #cyberbullying, loss of sleep, or reduced physical activity. https://t.co/CGt63GnW7J @russellviner pic.twitter.com/J7SuMORjLj
— The Lancet Child & Adolescent Health (@LancetChildAdol) August 13, 2019
ADA Guideline Synopsis: Diabetes Technology
13 Aug, 2019 | 08:00h | UTCOriginal Guideline: ADA 2019 Standards of Medical Care in Diabetes (free)
[Abstract Only] Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events
13 Aug, 2019 | 05:51h | UTCLong-term adverse events after sleeve gastrectomy or gastric bypass: a 7-year nationwide, observational, population-based, cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentary: Death Risk Drops After Bariatric Surgery in Obese Patients – MedPage Today (free registration required)
Related Research: Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)
Related Commentary on Twitter
Long-term adverse events after #sleeve #gastrectomy or #gastric #bypass: a 7-year nationwide, observational, population-based, cohort study https://t.co/yRJg3y1SUp #bariatricsurgery pic.twitter.com/KP6u5cQWf6
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) August 8, 2019
[Abstract Only] Diabetes Subgroups Have Different Risk of Diabetes-associated Diseases
13 Aug, 2019 | 05:53h | UTCRisk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: a 5-year follow-up study – The Lancet Diabetes & Endocrinology (link to abstract and commentaries)
Commentaries: Different diabetes phenotypes associated with varying prevalence of complications – ACP Diabetes (free) AND Cluster analysis may help to predict diabetic complications – medwire News (free)
Related Study: Novel subgroups of adult-onset diabetes and their association with outcomes (link to abstract and commentaries)
Related Commentary on Twitter
What is the risk of diabetes-associated diseases in #subgroups of patients with recent-onset #diabetes? Find out in this 5-year follow-up study https://t.co/ZPYUv4IsQd #clusters #PrecisionMedicine #NAFLD #diabetic #neuropathy pic.twitter.com/9VZnl3DjKj
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) August 9, 2019
Cohort Study: Association of Hearing Loss with Dementia
13 Aug, 2019 | 05:24h | UTCAssociation of Hearing Loss With Dementia – JAMA Network Open (free)
Commentary: Middle-age hearing loss linked to dementia – Reuters (free)
Related Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function (free study and commentaries)