Family Medicine
[Abstract Only] Study: Overdiagnosis of COPD in Subjects with Unobstructed Spirometry
4 Sep, 2019 | 08:29h | UTCOverdiagnosis of COPD in Subjects With Unobstructed Spirometry – CHEST (link to abstract – $ for full-text)
Commentary: How Many Patients with Diagnosed COPD Truly Have It? – NEJM Journal Watch (free for a limited period)
#ESCCongress – Observational Study Finds Metabolic Surgery May Reduce the Risk of Death and Cardiovascular Complications in Diabetic Patients
3 Sep, 2019 | 01:22h | UTCAssociation of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)
Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)
Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)
Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)
Meta-Analysis: Menopausal Hormone Therapy Increases Breast Cancer Risk
30 Aug, 2019 | 08:55h | UTCCommentaries: Menopausal hormones: definitive evidence for breast cancer – The Lancet (free) AND Menopausal hormone therapy and 20-year breast cancer mortality – The Lancet (free) AND Hormone therapy during menopause raises breast cancer risk for years, study finds – STAT (free) AND Expert reaction to study looking at HRT use and risk of breast cancer – Science Media Centre (free)
Screening for Social Determinants of Health: The Known and Unknown
30 Aug, 2019 | 08:30h | UTCScreening for Social Determinants of Health: The Known and Unknown – JAMA (free)
Commentary: JAMA paper: Doctors encouraged to consider social determinants screening, referrals – Northwell Health (free)
[Abstract Only] Cohort Study: Fruit and Cereal Fiber Linked to Lower Risk of Diverticulitis
30 Aug, 2019 | 08:20h | UTCIntake of Dietary Fiber, Fruits, and Vegetables and Risk of Diverticulitis – American Journal of Gastroenterology (link to abstract – $ for full-text)
Commentary: More fruit and cereal fiber tied to less risk of common bowel disease – Reuters (free)
NICE Guideline: Management of Type 2 Diabetes in Adults
29 Aug, 2019 | 06:56h | UTCType 2 diabetes in adults: management – National Institute for Health and Care Excellence (free)
Related Guideline: ADA 2019 Standards of Medical Care in Diabetes (free supplement)
NICE Guideline: Management of Hypertension in Adults
29 Aug, 2019 | 06:54h | UTCHypertension in adults: diagnosis and management – National Institute for Health and Care Excellence (free)
Related Guidelines: 2017 Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines (free) AND 2018 ESC/ESH Guidelines for the management of arterial hypertension – European Heart Journal (free)
Meta-Analysis: Estrogen-Based Hormone Therapy Does Not Improve Muscle Mass in Postmenopausal Women
29 Aug, 2019 | 06:08h | UTCCommentary: Hormone Therapy Doesn’t Prevent Age-Related Muscle Loss in Women – Medscape (free registration required)
Randomized Trial: High-Dose Vitamin D Supplementation Does Not Improve Bone Health and May Result in Lower Bone Mineral Density
28 Aug, 2019 | 02:33h | UTCEffect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial – JAMA (free for a limited period)
Commentary: High-Dose Vitamin D Might Reduce Bone Mineral Density – NEJM Journal Watch (free)
Related Commentary on Twitter
Vitamin D study: "Among healthy adults, supplementation with higher doses of vitamin D did not improve bone health." https://t.co/pugZ4Ilxke via @JAMA_current @SMCCanada cc @DietitiansCAN @medmyths @joansalgeblake @picardonhealth @CBCHealth pic.twitter.com/4BocJC1EeT
— Timothy Caulfield (@CaulfieldTim) August 27, 2019
Cohort Study: Gout is Associated with Increased Risk of Advanced Chronic Kidney Disease
29 Aug, 2019 | 05:45h | UTCCommentaries: Gout ‘more than doubles’ risk of kidney failure – University of Limerick (free) AND Gout pushes up kidney disease risks, study says – UPI (free)
USPSTF Recommends Screening for Hepatitis C in All Adults
28 Aug, 2019 | 02:32h | UTCCommentary: HCV Screening Now Recommended for All Adults – NEJM Journal Watch (free)
ACOG Recommendations: Screening and Management of Bleeding Disorders in Adolescents with Heavy Menstrual Bleeding
28 Aug, 2019 | 02:30h | UTCCommentary: ACOG advises bleeding disorder screening for teens with heavy menstruation – ObGyn News (free)
Cohort Study: How Many Older Adults Receive Drugs of Questionable Clinical Benefit Near the End of Life?
28 Aug, 2019 | 02:26h | UTCRelated Studies: Use of Medications of Questionable Benefit at the End of Life (link to abstract and commentaries) AND Preventive Drugs in the Last Year of Life of Older Adults with Cancer: Is There Room for Deprescribing? (link to abstract and commentary)
Podcast: Common Complete Blood Count (CBC) Abnormalities
28 Aug, 2019 | 02:13h | UTC#167 LIVE! Common CBC Abnormalities with Mary Kwok MD – The Curbsiders Internal Medicine Podcast (free)
Perspective: Why Doctors Still Offer Treatments That May Not Help
27 Aug, 2019 | 01:55h | UTCWhy Doctors Still Offer Treatments That May Not Help – The New York Times (10 articles per month are free)
Related: When Evidence Says No, But Doctors Say Yes – ProPublica (free) AND Meta-Research: A Comprehensive Review of Randomized Trials Leading to “Medical Reversals” in Three Medical Journals (free) AND 10 Medical Myths We Should Stop Believing. Doctors, Too. – The New York Times (10 articles per month are free)
Podcast: Diabetes Update
27 Aug, 2019 | 01:54h | UTC#168 Diabetes Update with Jeff Colburn MD – The Curbsiders Internal Medicine Podcast (free audio and summary)
Cohort Study: Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
27 Aug, 2019 | 01:49h | UTCAssociation of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality – JAMA Internal Medicine (free for a limited period)
Commentary: More plant protein tied to longer life – Reuters (free)
Related Studies: Plant‐Based Diets Are Associated with a Lower Risk of Cardiovascular Disease and All‐Cause Mortality (free) AND Healthful and Unhealthful Plant-Based Diets and the Risk of Coronary Heart Disease (link to abstract and commentaries) AND Cohort Study: Fruit, vegetable, and legume intake, and cardiovascular disease and deaths (link to abstract and commentaries)
Study: Acute Gallbladder or Biliary Disease More Common in Patients Using Liraglutide
27 Aug, 2019 | 00:31h | UTCEffects of Liraglutide Compared With Placebo on Events of Acute Gallbladder or Biliary Disease in Patients With Type 2 Diabetes at High Risk for Cardiovascular Events in the LEADER Randomized Trial – Diabetes Care (free PDF for a limited period)
Commentary: Gallbladder, Biliary Tract Events Increased With Liraglutide – Medscape (free registration required)
[Abstract Only] Study: High Animal Protein Intake Linked to Increased Risk of Kidney Stones
27 Aug, 2019 | 00:26h | UTCPlant and Animal Protein Intakes and Risk of Incident Kidney Stones: Results from the Shanghai Men’s and Women’s Health Studies – Journal of Urology (link to abstract – $ for full-text)
Commentary: Kidney Stones Linked to High Animal Protein Intake – Renal & Urology News (free)
Related: NICE Guideline – Renal and Ureteric Stones: Assessment and Management (free guidelines on the subject) AND Fluid Intake and Dietary Factors and the Risk of Incident Kidney Stones in UK Biobank: A Population-based Prospective Cohort Study – European Urology Focus (free)
Study: High Blood Pressure in Adulthood Linked to Late-life Brain Structure Changes
25 Aug, 2019 | 21:32h | UTCCommentaries: Blood pressure control as an intervention to prevent dementia – The Lancet Neurology (free) AND Early blood pressure changes linked to poorer brain health – University College London (free) AND High blood pressure in mid-30s may pose risk to brain health – BBC (free) AND Blood pressure in our 30s and 40s has lasting impact on brain health – Medical News Today (free)
Related Study: Midlife to Late-Life Blood Pressure Patterns and Incident Dementia (link to abstract and commentaries)
Related Commentary on Twitter
Rising blood pressure in people as young as 36 is linked to markers of poorer brain health in later life, including blood vessel damage and brain shrinkage, finds a new study led by Prof Jonathan Schott @jmschott @UCLIoN @drcionucl @UKDRI @TheLancetNeuro https://t.co/fTZR8cdLlv
— UCL News (@uclnews) August 21, 2019
Summary of ACIP/CDC Adult Immunization Updates
25 Aug, 2019 | 21:12h | UTCAdult Immunization Update – JAMA (free for a limited period)
See also: Recommended Adult Immunization Schedule for ages 19 years or older – Centers for Disease Control and Prevention (CDC) / Advisory Committee on Immunization Practices (ACIP) (free PDF)
Meta-Analysis: Any Level of Physical Activity Decreases Risk of Premature Death
25 Aug, 2019 | 21:05h | UTCEditorial: Every step you take – The BMJ (free)
Commentaries: “Sit less—move more and more often”: all physical activity is beneficial for longevity – The BMJ Opinion (free) AND ‘Sit less, move more’ may be key advice for living longer – NHS Choices (free) AND Every Little Step Helps – Any Physical Activity Linked to Decreased Mortality – MedicalResearch.com (free)
[Abstract Only] Randomized Trial: Effectiveness of Polypill for Primary and Secondary Prevention of Cardiovascular Diseases
23 Aug, 2019 | 08:48h | UTCEffectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)
Commentaries: 4-Drug Polypill Cuts CV Risk – NEJM Journal Watch (free) AND Four-in-one pill prevents third of heart problems – BBC (free)
Related: Clinical Impact of the Polypill for Cardiovascular Prevention in Latin America: A Consensus Statement of the Inter-American Society of Cardiology – Global Heart (free) AND Perspective: The Polypill and the Long Journey to Major Impact (opinion and reviews on the subject) AND Research: Low-Dose ‘Triple Pill’ Lowers Blood Pressure More Than Usual Care (free commentaries)
Related Commentary on Twitter
NEW Research—Large five-year randomised trial supports use of #polypill to prevent #CVD: finding from PolyIran, a pragmatic, cluster-randomised trial #LancetCardiology #ESCCongress https://t.co/YtU4MBPWom pic.twitter.com/GocADDE7Kv
— The Lancet (@TheLancet) August 23, 2019
Cohort Study: Association of Smoking Cessation With Subsequent Risk of Cardiovascular Disease
23 Aug, 2019 | 08:46h | UTCAssociation of Smoking Cessation With Subsequent Risk of Cardiovascular Disease – JAMA (free for a limited period)
Commentaries: Smoking Cessation and Reduction of Cardiovascular Disease Risk – JAMA (free for a limited period) AND Effects of smoking on the heart, blood vessels take at least a decade to fade – UPI (free)
Study: High Prevalence of Celiac Disease Among Screened First-Degree Relatives
23 Aug, 2019 | 08:33h | UTCHigh Prevalence of Celiac Disease Among Screened First-Degree Relatives – Mayo Clinic Proceedings (free for a limited period)
Commentary: Study calls for screening of all first-degree relatives of celiac disease patients – News Medical (free)