Family Medicine
Richard Lehman’s Covid-19 Reviews—11 May 2020
12 May, 2020 | 03:22h | UTCRichard Lehman’s Covid-19 Reviews, 11 May 2020 – The BMJ Opinion
In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19
2020 ACR Guideline for the Management of Gout
12 May, 2020 | 03:14h | UTCNews Release: ACR releases gout management guideline
[Abstract Only] Study: Folic Acid Supplement Linked to Increased Risk of Gestational Hypertension
12 May, 2020 | 03:13h | UTCFolic Acid Supplement Use and Increased Risk of Gestational Hypertension – Hypertension
News Release: Prenatal supplement may increase blood pressure at high doses – American Heart Association
Perspective: When Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials?
11 May, 2020 | 00:23h | UTCWhen Should Clinicians Act on Non–Statistically Significant Results From Clinical Trials? – JAMA (via @AndersPerner)
Author Interview: When Should Physicians Act on Non–Statistically Significant Results From Clinical Trials?
“The burden of proof required to do “more” should probably be higher than to do “less,” particularly if doing “more” is likely to increase overall health care costs.”
Canadian Guideline: Acetylsalicylic Acid for Prevention of Vascular Events
11 May, 2020 | 00:05h | UTC
Study: Combustible vs. Electronic Cigarettes Alterations in Vascular Function
11 May, 2020 | 00:10h | UTCCommentary: Like Tobacco, Long-term E-Cigarettes Harm Vascular Function – TCTMD AND Vascular Damage Similar With E-cigarettes, Traditional Cigarettes – American College of Cardiology
COVID-19 in Older People: A Rapid Clinical Review
8 May, 2020 | 10:22h | UTCCOVID-19 in Older People: A Rapid Clinical Review – Age and Ageing
Interpreting Diagnostic Tests for SARS-CoV-2
7 May, 2020 | 09:28h | UTCInterpreting Diagnostic Tests for SARS-CoV-2 – JAMA
Case Series: Hyperinflammatory Shock in Children During COVID-19 Pandemic
7 May, 2020 | 09:21h | UTCHyperinflammatory shock in children during COVID-19 pandemic – The Lancet
Commentaries: Researchers report “unprecedented cluster” of inflammatory problems in children amid pandemic – CNN AND Expert reaction to report on 8 children with hyperinflammatory shock during the COVID-19 pandemic – Science Media Centre AND Mysterious inflammatory syndrome in children potentially linked to COVID-19 reported in Montreal – National Post AND A New Coronavirus Threat to Children – The New York Times AND What to Know About Kawasaki Disease, the Pediatric Inflammatory Condition Possibly Linked to COVID-19 – TIME AND Kawasaki Disease—The Latest Weird Illness From Coronavirus – Forbes
Reducing Risks from Coronavirus Transmission in the Home—The Role of Viral Load
7 May, 2020 | 09:01h | UTCReducing risks from coronavirus transmission in the home—the role of viral load – The BMJ
Commentaries: Can we do more to protect people at home when a family member has coronavirus? – University of Bristol AND Coronavirus: Exposure to higher ‘viral load’ when infected could make victims more severely ill – Yahoo News
2020 International Society of Hypertension Global Hypertension Practice Guidelines
7 May, 2020 | 09:00h | UTC2020 International Society of Hypertension Global Hypertension Practice Guidelines – Hypertension
Should Schools Reopen? Kids’ Role in Pandemic Still a Mystery
6 May, 2020 | 03:50h | UTCShould schools reopen? Kids’ role in pandemic still a mystery – Science
Related: Did Closing Schools Actually Help? – The New York Times AND New Studies Add to Evidence that Children May Transmit the Coronavirus – The New York Times AND When Should Schools Reopen? – Center for Global Development AND Systematic Review: School Closure During Coronavirus Outbreaks AND Children are not COVID-19 super spreaders: time to go back to school – Archives of Disease in Childhood
COVID-19: AMA Step-by-step Guide for Physicians Planning to Reopen Medical Practices
6 May, 2020 | 04:00h | UTCCOVID-19: A physician practice guide to reopening – American Medical Association
News Release: AMA launches physician guide for reopening medical practices
Tests in Recovered Patients Found to be False Positives, Not Reinfections
6 May, 2020 | 03:48h | UTCTests in recovered patients found false positives, not reinfections, experts say – The Korea Herald
See also: Recovered patients who tested positive for COVID-19 likely not reinfected – Live Science AND South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up ‘dead virus fragments’ – Business Insider
Systematic Review: Chloroquine and Hydroxychloroquine as a Treatment for COVID‐19
6 May, 2020 | 03:44h | UTC“Pending further results from more extensive studies with more stringent study parameters, clinicians should defer from routine use of HCQ and CQ.”
Perspective: Treatments Can Harm
6 May, 2020 | 03:38h | UTCTreatments can harm – Evidently Cochrane
Related: Treatments can harm – Students 4 Best Evidence (commentary and EBM resource) AND Patients’ Expectations of the Benefits and Harms of Treatments, Screening, and Tests: A Systematic Review – JAMA Internal Medicine AND If Patients Only Knew How Often Treatments Could Harm Them – The New York Times
Perspective: The Cost of Technology
6 May, 2020 | 03:35h | UTC
Obesity Could Shift Severe COVID-19 Disease to Younger Ages
5 May, 2020 | 04:53h | UTCObesity could shift severe COVID-19 disease to younger ages – The Lancet
NEW Correspondence—D Kass et al examined the correlation between BMI & age in 265 #COVID19 patients admitted to ICU at 6 hospitals & found a significant inverse correlation between age & BMI, in which younger individuals were more likely to be obese https://t.co/SrNSp2W7JQ pic.twitter.com/ozpBug5Mv9
— The Lancet (@TheLancet) May 1, 2020
[Abstract Only] Randomized Trial: No Benefit from L-thyroxine Among Elderly Patients with Symptomatic Subclinical Hypothyroidism
5 May, 2020 | 04:11h | UTCL-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: L-thyroxine did not improve symptoms or tiredness in older patients with subclinical hypothyroidism – ACP Internist AND More Evidence Against L-Thyroxine for Subclinical Hypothyroidism – NEJM Journal Watch
Related Articles: Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine
Recommendations for the Management of Lower Urinary Tract Infections in Pregnant and Non-pregnant Women
5 May, 2020 | 03:57h | UTC
Study: In Utero Antidepressants and Neurodevelopmental Outcomes in Kindergarteners
5 May, 2020 | 03:47h | UTCIn Utero Antidepressants and Neurodevelopmental Outcomes in Kindergarteners – Pediatrics
Commentaries: Providing the Evidence for Managing Depression in Pregnancy – Pediatrics AND Adverse neurodevelopmental outcomes linked to prenatal exposure to antidepressants – 2 Minute Medicine
Systematic Review: Corticosteroids as Standalone or Add‐on Treatment for Sore Throat
5 May, 2020 | 03:36h | UTCCorticosteroids as standalone or add‐on treatment for sore throat – Cochrane Library
Summary: Corticosteroids as standalone or add‐on treatment for sore throat – Cochrane Library
Characteristics of 100 Children with Covid-19
3 May, 2020 | 22:29h | UTCChildren with Covid-19 in Pediatric Emergency Departments in Italy – New England Journal of Medicine
Related Systematic Review: SARS-CoV-2 Infection in Children and Adolescents (study and commentaries)
New NICE Coronavirus Rapid Guidelines
3 May, 2020 | 22:46h | UTC- COVID-19 rapid guideline: antibiotics for pneumonia in adults in hospital – National Institute for Health and Care Excellence
- COVID-19 rapid guideline: gastrointestinal and liver conditions treated with drugs affecting the immune response – National Institute for Health and Care Excellence
- COVID-19 rapid guideline: children and young people who are immunocompromised – National Institute for Health and Care Excellence
See Previous NICE Coronavirus Guidelines: Rapid guidelines and evidence summaries – National Institute for Health and Care Excellence
New Observational Studies Confirm the Safety of Renin–Angiotensin–Aldosterone System Blockers in Patients with Covid-19
3 May, 2020 | 22:32h | UTCStudy 3: Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 – New England Journal of Medicine
Commentary: Blood Pressure Drugs Don’t Increase Coronavirus Risk, Studies Find – The New York Times
See also: Observational Study: Renin-Angiotensin System Inhibitors are Not Associated with Severity or Mortality in Hospitalized Patients with Coronavirus Disease (2 other studies on the subject)