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Family Medicine

Global burden of cardiovascular diseases and risk factors, 1990–2019

10 Dec, 2020 | 09:00h | UTC

Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019: Update From the GBD 2019 Study – Journal of the American College of Cardiology

News Release: JACC: Cardiovascular Disease Burden, Deaths Are Rising Around the World – Institute for Health Metrics and Evaluation

 

Commentary on Twitter

https://twitter.com/IHME_UW/status/1336792746842058756

 


Systematic Review: Probiotics probably make little or no difference for patients with acute infectious diarrhea

10 Dec, 2020 | 08:53h | UTC

Probiotics for treating acute infectious diarrhoea – Cochrane Library

Summary: Do probiotics help to treat acute infectious diarrhoea? – Cochrane Library

 


Systematic review: Men with COVID-19 have almost three times the risk of requiring ICU admission and a higher risk of death

10 Dec, 2020 | 08:45h | UTC

Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission – Nature Medicine

Commentary: Men face ‘almost three times the odds’ of ICU admission for Covid-19, study says – CNN AND Men with COVID-19 three times more likely to need intensive care: study – MedicalXpress

 

Commentary on Twitter

 


Randomized trial: In patients with recurrent, complicated, or persistent painful diverticulitis, sigmoid resection improved quality of life but was associated with a small but significant risk of major complications

10 Dec, 2020 | 08:51h | UTC

Comparing Laparoscopic Elective Sigmoid Resection With Conservative Treatment in Improving Quality of Life of Patients With Diverticulitis: The Laparoscopic Elective Sigmoid Resection Following Diverticulitis (LASER) Randomized Clinical Trial – JAMA Surgery

Author Interview: Laparoscopic Sigmoid Resection vs Conservative Treatment in Improving Quality of Life in Diverticulitis

Commentary: Laparoscopic sigmoid resection for recurrent diverticulitis associated with higher quality of life scores – 2 Minute Medicine

 

Commentary on Twitter

https://twitter.com/drferzli/status/1330948905941557248

 


UK to refine allergy warning on Pfizer vaccine sparked by two adverse reactions

10 Dec, 2020 | 08:41h | UTC

UK to refine allergy warning on Pfizer vaccine sparked by two adverse reactions – Reuters

See also: UK probes whether COVID-19 vaccine caused allergic reactions – Associated Press AND NHS told not to give Covid vaccine to those with history of allergic reactions – The Guardian

 


CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk

9 Dec, 2020 | 08:23h | UTC

CDC Releases New Ventilation Guidelines For Indoor Environments To Reduce Covid-19 Risk – Forbes

CDC Guideline: Ventilation

Related podcast: Air Handling Standards for Increasing the Safety of Indoor Spaces During the COVID-19 Pandemic – JAMA

 


Vast majority of pregnant women with COVID-19 won’t have complications, study finds

10 Dec, 2020 | 08:39h | UTC

Vast Majority of Pregnant Women with COVID-19 Won’t Have Complications, Study Finds – NIH Director’s Blog

Original study: Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection – JAMA Network Open

 


Just published: AstraZeneca-Oxford Covid-19 vaccine shows moderate efficacy, but questions remain about the most effective dosing regimen

9 Dec, 2020 | 08:25h | UTC

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK – The Lancet

Commentaries: Oxford COVID vaccine paper highlights lingering unknowns about results – Nature AND Detailed data on AstraZeneca-Oxford Covid-19 vaccine show it has moderate efficacy – STAT AND Oxford–AstraZeneca COVID-19 vaccine efficacy – The Lancet AND Oxford COVID-19 vaccine is safe and protects against disease, first published results from phase 3 trials – The Lancet AND Expert reaction to a study on the results of phase 3 human trials of the Oxford/AZ COVID-19 vaccine – Science Media Centre

 


“COVID-19: when are you most infectious?” This commentary from the authors of a recent meta-analysis highlights the findings that infectiousness peaks within the first 5 days of symptom onset

10 Dec, 2020 | 08:38h | UTC

COVID-19: when are you most infectious? – The Conversation

Original study and commentaries: Meta-analysis: SARSCoV2 most contagious within the first 5 days of symptom onset

 


Another randomized trial shows hydroxychloroquine is not effective as postexposure prophylaxis to prevent Covid-19

9 Dec, 2020 | 08:19h | UTC

Hydroxychloroquine as Postexposure Prophylaxis to Prevent Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Randomized Trial – Annals of Internal Medicine

Summary for patients: Summary for Patients: Postexposure Hydroxychloroquine Prophylaxis to Prevent SARS-CoV-2 Infection

 


Randomized trial: No benefit and potential harm from Vitamin D at doses of 1000 IU/d or higher compared with 200 IU/d in older persons with elevated fall risk

9 Dec, 2020 | 08:13h | UTC

The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults: A Response-Adaptive, Randomized Clinical Trial – Annals of Internal Medicine

Commentaries: Study Finds No Benefit, Possible Harm to Seniors’ Fall Risks with Higher Doses of Vitamin D – Johns Hopkins Medicine AND Does High-Dose Vitamin D Actually Heighten Fall Risk? – Physician’s Weekly

 

Commentary on Twitter (thread – click for more)

https://twitter.com/ErinMichos/status/1336091776994537472

 


Cohort study: In the general population, both low and high levels of LDL cholesterol were associated with an increased risk of all-cause mortality

9 Dec, 2020 | 08:11h | UTC

Association between low density lipoprotein and all cause and cause specific mortality in Denmark: prospective cohort study – The BMJ

 

Commentary on Twitter

 


If exposed to Covid-19, how long before you have symptoms? Median incubation is 5.1 days, and 97.5% of those who develop symptoms do so within 11.5 days of being exposed to the virus

8 Dec, 2020 | 08:06h | UTC

If Exposed To Covid-19 Coronavirus, How Long Before You Have Symptoms – Forbes

 


Opinion: “Get ready for vaccine false side effects”. When millions of people are vaccinated, naturally occurring health problems could be wrongly attributed to vaccines

8 Dec, 2020 | 07:55h | UTC

Get Ready for False Side Effects – Science Translational Medicine

 


First-of-its-kind African trial tests common drugs to prevent severe COVID-19. “Could cheap, widely available drugs prevent patients with mild illness from becoming severely sick?”

8 Dec, 2020 | 07:46h | UTC

First-of-its-kind African trial tests common drugs to prevent severe COVID-19 – Science

 


Observational study: Even low dose oral glucocorticoids linked to increased cardiovascular risk in people with immune-mediated inflammatory diseases

8 Dec, 2020 | 07:35h | UTC

Dose-dependent oral glucocorticoid cardiovascular risks in people with immune-mediated inflammatory diseases: A population-based cohort study – PLOS Medicine

Commentary: Patients receiving low dose steroid at increased risk of cardiovascular disease – Public Library of Science

 


Randomized trial: In pregnant women with mild and moderate chronic hypertension, the use of labetalol was associated with more adverse events compared to methyldopa or no medication

8 Dec, 2020 | 07:26h | UTC

Methyldopa versus labetalol or no medication for treatment of mild and moderate chronic hypertension during pregnancy: a randomized clinical trial – Hypertension in Pregnancy

Commentary: Methyldopa versus labetalol or no medication for the treatment of mild and moderate chronic hypertension during pregnancy: a randomized clinical trial – Physician’s Weekly

 


New CDC Guidance with 10 public health strategies to address high levels of community transmission of SARS-Cov-2, including universal use of face masks

7 Dec, 2020 | 01:10h | UTC

Summary of Guidance for Public Health Strategies to Address High Levels of Community Transmission of SARS-CoV-2 and Related Deaths, December 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: Masks are critical to stopping coronavirus spread, even at home, CDC says – CNN AND CDC recommends ‘universal’ use of face masks to prevent COVID-19 spread – UPI

 

Commentary on Twitter

 


Spironolactone use is associated with improved outcomes in patients with heart failure with preserved ejection fraction and concomitant resistant hypertension

8 Dec, 2020 | 07:44h | UTC

Spironolactone Use and Improved Outcomes in Patients With Heart Failure With Preserved Ejection Fraction With Resistant Hypertension – Journal of the American Heart Association

Commentary: Spironolactone use associated with improved outcomes for patients with HFpEF and resistant hypertension – 2 Minute Medicine

 


Meta-analysis: Respiratory function post-infection by COVID-19. Altered diffusion capacity, restrictive pattern, and obstructive pattern were found in 39%, 15% and 7% of patients, respectively

7 Dec, 2020 | 01:04h | UTC

Respiratory function in patients post-infection by COVID-19: a systematic review and meta-analysis – Pulmonology

 

Commentary on Twitter

 


Study in Germany comparing regions with vs. without mask mandates concluded that 20 d after becoming mandatory, face masks reduced new Covid-19 infections by around 45%

7 Dec, 2020 | 00:46h | UTC

Face masks considerably reduce COVID-19 cases in Germany – Proceedings of the National Academy of Sciences

 


Case-control study: Meningococcus B vaccine prevents disease with 79 percent effectiveness in children and young adults

6 Dec, 2020 | 23:48h | UTC

Association of Use of a Meningococcus Group B Vaccine With Group B Invasive Meningococcal Disease Among Children in Portugal – JAMA

Commentary: Meningococcus B vaccine prevents disease with 79 per cent effectiveness in under-18s – University of Bristol

 

Commentary on Twitter

 


Randomized trial: High-dose influenza vaccine shows no additional benefit for heart disease patients

7 Dec, 2020 | 00:44h | UTC

Effect of High-Dose Trivalent vs Standard-Dose Quadrivalent Influenza Vaccine on Mortality or Cardiopulmonary Hospitalization in Patients With High-risk Cardiovascular Disease: A Randomized Clinical Trial – JAMA

Editorial: Influenza Vaccine for Patients With High-risk Cardiovascular Disease

Commentary: High-dose influenza vaccine shows no additional benefit for heart disease patients – NIH News Releases

 

Commentary on Twitter

 


Meta-analysis reinforces the safety of betablockers in patients with COPD and cardiovascular disease

6 Dec, 2020 | 23:30h | UTC

Association of β-blocker use with survival and pulmonary function in patients with chronic obstructive pulmonary and cardiovascular disease: a systematic review and meta-analysis – European Heart Journal

Commentary: Beta-Blockers in Patients With COPD and CVD – American College of Cardiology

 


Teledermatology used for triage reduces dermatology referrals and improves access to specialists in the most severe or surgical cases

6 Dec, 2020 | 23:37h | UTC

Teledermatology reduces dermatology referrals and improves access to specialists – EClinicalMedicine

 


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