Family Medicine
Brief Review | Management of pituitary incidentalomas
25 Apr, 2023 | 14:14h | UTCManagement of pituitary incidentalomas – Clinical Medicine Journal
Brief Review | Investigation and assessment of adrenal incidentalomas
25 Apr, 2023 | 14:13h | UTCInvestigation and assessment of adrenal incidentalomas – Clinical Medicine Journal
Brief Review | Thyroid disease in pregnancy
25 Apr, 2023 | 14:15h | UTCThyroid disease in pregnancy – Clinical Medicine Journal
USPSTF Statement | There is insufficient evidence to guide skin cancer screening recommendations
24 Apr, 2023 | 14:07h | UTCScreening for Skin Cancer: US Preventive Services Task Force Recommendation Statement – JAMA
Evidence Report: Skin Cancer Screening: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorials:
Patient Page: Screening and Prevention of Skin Cancer – JAMA
Author Interview: USPSTF Recommendation: Screening for Skin Cancer – JAMA
Commentary on Twitter
2023 Recommendation Statement from the USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of visual skin examination by a clinician to screen for #skincancer in adolescents and adults (I statement). https://t.co/WB6VN2r1Nv
— JAMA (@JAMA_current) April 18, 2023
WHO releases first-ever Standard on universal access to rapid TB diagnostics
24 Apr, 2023 | 14:04h | UTCNews Release: WHO releases first-ever Standard on universal access to rapid TB diagnostics – World Health Organization
WHO Standard: Universal access to rapid tuberculosis diagnostics – World Health Organization
RCT | Oral fluvoxamine plus inhaled budesonide reduced hospitalizations in high-risk patients with early-onset COVID-19
24 Apr, 2023 | 13:51h | UTC
Commentary on Twitter
Treatment w/ oral fluvoxamine + inhaled budesonide among high-risk outpatients w/ early #COVID19 reduced incidence of severe disease requiring advanced care. The combined effect seems to offer benefits over individual use of each drug: https://t.co/wM2da5a5MD pic.twitter.com/Sl1qFzTOjD
— Annals of Int Med (@AnnalsofIM) April 19, 2023
RCT | Bariatric–metabolic surgery is more effective than lifestyle intervention plus best medical care in non-alcoholic steatohepatitis
24 Apr, 2023 | 14:03h | UTCNews Release: Surgery most effective treatment of metabolic liver disease – King’s College London
Commentary on Twitter
New @TheLancet – Verrastro et al – Bariatric–metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trialhttps://t.co/pCWahvbReQ#NASH #NAFLD #fattyliver #livertwitter pic.twitter.com/xNMsAskJF9
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) April 21, 2023
RCT | Higher dose corticosteroids increase mortality in hypoxic COVID-19 patients on simple oxygen
24 Apr, 2023 | 13:55h | UTCEditorial: Higher-dose dexamethasone for patients with COVID-19 and hypoxaemia? – The Lancet
Commentary: Higher-dose corticosteroids tied to 60% more deaths in low-oxygen COVID patients – CIDRAP
Commentary on Twitter (thread – click for more)
Low-dose corticosteroids have been shown to reduce mortality for patients with COVID-19 requiring oxygen or ventilatory support.
A new study evaluated the use of a higher dose of corticosteroids in this patient group. https://t.co/uJGSYSBQAO
— The Lancet (@TheLancet) April 13, 2023
Evidence Analysis | Blood pressure targets – how low can you get?
24 Apr, 2023 | 13:47h | UTCBlood pressure targets – how low can you get? – Evidently Cochrane
Original Article: SR | Blood pressure targets for the treatment of people with hypertension and cardiovascular disease.
Commentary on Twitter
Blood pressure targets – how low can you get? https://t.co/ERLm6Mihl8 In this @CochraneUK blog, GP @rtwalton123 looks at the latest guidance & @CochraneLibrary evidence on what #BloodPressure targets to aim for, balancing the benefits of treatment against risk of side effects. pic.twitter.com/8EQH0JLzzc
— The Cochrane Library (@CochraneLibrary) April 19, 2023
Guideline Update | Diagnosis and management of hypertension in pregnancy
24 Apr, 2023 | 13:43h | UTC
Cohort Study | Prenatal exposure to antiseizure medication and incidence of childhood-onset psychiatric disorders
24 Apr, 2023 | 13:10h | UTCPrenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders – JAMA Neurology (link to abstract – $ for full-text)
Author Interview: Prenatal Exposure to Antiseizure Medication and Psychiatric Disorders – JAMA
Commentary on Twitter
Study strengthens the evidence for the warning against the use of valproate in pregnancy, supports concerns about the use of topiramate, and provides a preliminary indication for caution with the use of levetiracetam in pregnancy. https://t.co/BZzZP0tSZs
— JAMA Neurology (@JAMANeuro) April 17, 2023
RCT | Intermittent fasting plus early time-restricted eating vs. calorie restriction and standard care in adults at risk of type 2 DM
24 Apr, 2023 | 13:07h | UTCIntermittent fasting plus early time-restricted eating versus calorie restriction and standard care in adults at risk of type 2 diabetes: a randomized controlled trial – Nature Medicine (if the link is paywalled, try this one)
News Release: Fasting diet reduces risk markers of type 2 diabetes – University of Adelaide
Related:
Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition
Commentary on Twitter
A study in @NatureMedicine comparing intermittent fasting plus early time-restricted eating (iTRE) to calorie restriction in adults at risk of type 2 diabetes shows that iTRE was associated with greater improvements in postprandial glucose metabolism. ? https://t.co/NsMn5xLvmE pic.twitter.com/gNbfGORhby
— Nature Portfolio (@NaturePortfolio) April 19, 2023
2023 ACC expert consensus on management of heart failure with preserved ejection fraction
21 Apr, 2023 | 13:10h | UTCCommentaries:
New Expert Consensus Papers Aim to Boost Management, Outcomes in HFpEF – TCTMD
Study estimates poor diet causes 70% of diabetes cases globally
21 Apr, 2023 | 13:06h | UTCIncident type 2 diabetes attributable to suboptimal diet in 184 countries – Nature Medicine
News Release: Study links poor diet to 14 million cases of type 2 diabetes globally – Tufts University
Commentary on Twitter
An analysis in @NatureMedicine estimates that 70% of new global cases of type 2 diabetes are attributable to suboptimal intake of 11 dietary factors, with substantial differences in dietary risks across world regions and nations. https://t.co/MYoLRt3rhO pic.twitter.com/Pv7I6Mhvxu
— Nature Portfolio (@NaturePortfolio) April 19, 2023
RCT | Pregnant individuals benefit from brief interpersonal psychotherapy for depression
21 Apr, 2023 | 13:05h | UTCCommentary: Interpersonal Psychotherapy Reduces Depression Symptoms of Pregnant Women – HCP Live
Commentary on Twitter
A randomized clinical trial of prenatal interpersonal psychotherapy showed rapid decreases in depression. Depression in the intervention group dropped from 37% before intervention to 6% after (vs. 26% in control group). https://t.co/rJADZZkfER
— JAMA Psychiatry (@JAMAPsych) April 19, 2023
Study shows that parathyroidectomy in adults with primary hyperparathyroidism probably has no effect on kidney function
21 Apr, 2023 | 12:57h | UTCEstimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults With Primary Hyperparathyroidism – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
New: #parathyroidectomy had no effect on long term #KidneyFunction in older adults w/ primary #hyperparathyroidism, but may preserve function in patients under 60. https://t.co/B456rPwGem pic.twitter.com/V8hLmrYiUX
— Annals of Int Med (@AnnalsofIM) April 17, 2023
Joint statement for assessing and managing high blood pressure in children and adolescents
19 Apr, 2023 | 13:26h | UTCChapter 1: How to correctly measure blood pressure in children and adolescents – Frontiers in Pediatrics
Chapter 2: How to manage high blood pressure in children and adolescents – Frontiers in Pediatrics
Related:
AHA Scientific Statement | Pediatric primary hypertension: An underrecognized condition
AHA Scientific Statement: Ambulatory blood pressure monitoring in children and adolescents.
Guideline | Management of psychiatric disorders in patients with hepatic and gastrointestinal diseases
19 Apr, 2023 | 13:07h | UTC
Study suggests that routine axillary scanning in diagnostic breast ultrasound has limited impact on cancer detection
19 Apr, 2023 | 13:06h | UTCTo scan or not to scan: effect of scanning the axilla of all patients undergoing diagnostic breast ultrasound – Clinical Imaging (link to abstract – $ for full-text)
Commentary: Is scanning the axilla during diagnostic breast ultrasound necessary? – Health Imaging
Opinion | Universal masking in health care settings: a pandemic strategy whose time has come and gone, for now
18 Apr, 2023 | 13:37h | UTC
Opinion | In-person schooling is essential even during periods of high transmission of COVID-19
18 Apr, 2023 | 13:36h | UTC
Comprehensive clinical practice guidelines for the management of psychiatric emergencies
18 Apr, 2023 | 13:34h | UTCClinical Practice Guidelines for Management of Suicidal Behaviour
Clinical Practice Guidelines for Assessment and Management of Aggressive and Assaultive Behaviour
Clinical Practice Guidelines on Breaking Bad News
Clinical Practice Guidelines for the Use of Electroconvulsive Therapy
Clinical Practice Guidelines for the Use of Transcranial Direct Current Stimulation in Psychiatry
Cluster RCT | Salt substitute outperforms salt restriction in lowering blood pressure in older patients
18 Apr, 2023 | 13:30h | UTCSalt substitution and salt-supply restriction for lowering blood pressure in elderly care facilities: a cluster-randomized trial – Nature Medicine (if the link is paywalled, try this one)
Commentary: Exploring effectiveness of salt substitutes in elderly care facilities – Medical Xpress
Related:
Salt substitutes vs. regular salt: a quick look.
Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis – Heart (link to abstract – $ for full-text)
RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients
Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths
Commentary on Twitter
In a cluster-randomized trial in 48 residential elderly care facilities in China, a low-sodium salt substitute instead of regular salt decreased blood pressure and cardiovascular events, while restricting salt consumption did not show beneficial effects https://t.co/Zp0fWH0aA2
— Nature Medicine (@NatureMedicine) April 13, 2023
Large-scale study finds genetic causes for 41% of rare pediatric diseases
18 Apr, 2023 | 13:25h | UTCGenomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland – New England Journal of Medicine (free for a limited period)
News Release: 5,500 people diagnosed with rare genetic diseases in major research study – University of Exeter
Commentary on Twitter
The DDD study recruited more than 13,500 families with probands with severe, probably monogenic disorders in the United Kingdom and Ireland and obtained a genetic diagnosis in approximately 41% of probands. https://t.co/W3pfg5HPEZ pic.twitter.com/eGb2yNsGBf
— NEJM (@NEJM) April 12, 2023
Guideline | Intrahepatic cholestasis of pregnancy
18 Apr, 2023 | 13:24h | UTCIntrahepatic cholestasis of pregnancy – BJOG