Family Medicine
Unnecessary care? 1 in 3 patients with advanced dementia and atrial fibrillation still given anticoagulants.
17 May, 2021 | 08:13h | UTCOriginal study: Anticoagulant Use for Atrial Fibrillation Among Persons With Advanced Dementia at the End of Life – JAMA Internal Medicine (free for a limited period)
Editorial: Anticoagulation at the End of Life: Time for a Rational Framework (free for a limited period)
Report: Implementing high-quality primary care – “pay for primary care teams to care for people, not physicians to deliver services”.
17 May, 2021 | 08:11h | UTCOriginal report: Implementing High-Quality Primary Care: Rebuilding the Foundation of Health Care – National Academies of Sciences, Engineering, and Medicine
Cohort study of 12,306 pediatric COVID-19 patients finds only 16.5% presented with typical respiratory symptoms (cough, dyspnea). 13.9% had GI symptoms, 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste).
14 May, 2021 | 08:48h | UTCCommentary: COVID-19: Majority of infected children may not show typical symptoms – Nature Publishing Group
Commentary on Twitter
A retrospective cohort study of 12,306 pediatric COVID-19 patients
📍5% require hospitalization
📍18% of these require critical care
📍4% of these require ventilation
https://t.co/X6MTdS8D1i— RJ MacDonald MD 🚴♂️🏄🏻🎾 (@Kidsdoc1Rick) May 13, 2021
Perspective | New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications.
14 May, 2021 | 08:43h | UTC
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
14 May, 2021 | 08:46h | UTCHeterologous prime-boost COVID-19 vaccination: initial reactogenicity data – The Lancet
Commentaries: More side effects noted after using 2 different COVID vaccines – CIDRAP AND Covid vaccines: Mixing increases reports of mild side-effects – BBC
Perspective | Vaccines seem to work well against coronavirus variants. It’s also complicated.
14 May, 2021 | 08:41h | UTCVaccines seem to work well against coronavirus variants. It’s also complicated – STAT
CDC says fully vaccinated Americans can go indoors and outdoors without masks.
14 May, 2021 | 08:38h | UTCCDC Guidance: Interim Public Health Recommendations for Fully Vaccinated People – Centers for Disease Control and Prevention
Commentaries: CDC backtracks, saying fully vaccinated people can go maskless indoors – STAT AND Fully Vaccinated People Can Stop Wearing Masks Indoors And Outdoors, CDC Says – NPR AND CDC: No masks needed for COVID-vaccinated Americans – CIDRAP
Editorial: Vaccinating children against SARS-CoV-2 – “Hard to justify right now for most children in most countries”.
14 May, 2021 | 08:39h | UTCVaccinating children against SARS-CoV-2 – The BMJ
Related: Pfizer COVID-19 shot expanded to US children as young as 12.
Large trial with over 200.000 patients finds ovarian cancer screening does not reduce deaths.
14 May, 2021 | 08:32h | UTCCommentaries: Screening for ovarian cancer did not reduce early deaths – Imperial College London AND Annual screening for ovarian cancer does not save lives, study finds – The Guardian
Review: How to interpret and use COVID-19 serology and immunology tests.
14 May, 2021 | 08:36h | UTC
Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens.
14 May, 2021 | 08:30h | UTCPodcast with the author: Dr Paula Rochon talks with The Lancet Healthy Longevity about polypharmacy in older people through a sex and gender lens
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject) AND Polypharmacy Management in Older Patients – Mayo Clinic Proceedings AND Psychopharmacological Treatment in Older People: Avoiding Drug Interactions and Polypharmacy – Deutsches Ärzteblatt internationa AND Eliminating Medication Overload: A National Action Plan AND Deprescribing in Older Adults With Cardiovascular Disease – Journal of the American College of Cardiology
Commentary on Twitter
NEW REVIEW: @RochonPaula and colleagues look at #polypharmacy & #deprescribing for #older people through a sex & gender lens
👀Read the #openaccess paper here: https://t.co/CpcJswOtt1
👂Listen to the new podcast with the authors here:https://t.co/EXg9wNlE9K pic.twitter.com/AZ4VkKt33p— The Lancet Healthy Longevity (@LancetLongevity) May 13, 2021
Systematic review: Combination fixed‐dose beta-agonist and steroid inhaler as required is clinically effective in adults and adolescents with mild asthma.
14 May, 2021 | 08:23h | UTC
RCT: Tezepelumab can reduce exacerbations in adults and adolescents with severe, uncontrolled asthma.
14 May, 2021 | 08:25h | UTCCommentary: New drug shows promise against tough-to-manage asthma – MedicalXpress
Simplified decision aid: neuropathic pain treatment options in primary care.
14 May, 2021 | 08:17h | UTC
Opinion | Let’s banish the term ‘patient’ from the health care lexicon.
14 May, 2021 | 08:19h | UTCLet’s banish the term ‘patient’ from the health care lexicon – STAT
[Not published yet] Observational study in Indonesia finds China’s Sinovac COVID-19 vaccine (CoronaVac) was 98% effective at preventing death and 96% effective at preventing hospitalization in healthcare workers
13 May, 2021 | 06:07h | UTCIndonesia study finds China’s Sinovac COVID-19 vaccine effective in medical staff – Reuters
Review: Pharmacotherapy management of schizophrenia for family physicians.
14 May, 2021 | 08:16h | UTCPharmacotherapy management of schizophrenia for family physicians – Canadian Family Physician
[Preprint] Observational study finds single-dose Johnson & Johnson vaccine is 76.7% effective in preventing SARS-CoV-2 infection
13 May, 2021 | 06:06h | UTCReal-World Effectiveness of Ad26.COV2.S Adenoviral Vector Vaccine for COVID-19 – The Lancet
Commentary on Twitter
One of the first studies to assess real-world effectiveness of the J&J 1-dose vaccine, matches Phase 3 clinical trial, at 77%https://t.co/3YgcML9YSh @MayoClinic @MayoClinicHS preprint pic.twitter.com/XOjQlUaHK2
— Eric Topol (@EricTopol) May 11, 2021
RCT: Tympanostomy-tube placement does not reduce episodes of acute otitis media among children 6 to 35 months of age with recurrent acute otitis media
13 May, 2021 | 05:57h | UTCCommentary: No lasting benefit to tubes over antibiotics for childhood ear infections – University of Pittsburgh
2021 EULAR recommendations for the implementation of self-management strategies in patients with inflammatory arthritis
13 May, 2021 | 05:49h | UTCCommentary: EULAR issues recommendations on self-management strategies for inflammatory arthritis – MedwireNews
Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).
12 May, 2021 | 08:55h | UTC
Pfizer COVID-19 shot expanded to US children as young as 12.
12 May, 2021 | 08:53h | UTCPfizer COVID-19 shot expanded to US children as young as 12 – Associated Press
Counterpoint: Covid vaccines for children should not get emergency use authorization – The BMJ Opinion
Commentaries: Covid-19: FDA authorises Pfizer vaccine for children 12-15 – The BMJ AND Expert reaction to U.S. FDA authorising Pfizer-BioNTech COVID-19 vaccine for emergency use in adolescents – Science Media Centre
Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk.
12 May, 2021 | 08:50h | UTCOriginal study: Factors Associated With Risk for Care Escalation Among Patients With COVID-19 Receiving Home-Based Hospital Care – Annals of Internal Medicine
Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient
Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.
12 May, 2021 | 08:47h | UTCCommentaries: Non-hospitalized COVID-19 patients: Low-risk of serious long-term effects, but more visits to doctor – The Lancet AND Any COVID-19 Infection Raises Odds for Lingering Symptoms, Study Finds – HealthDay AND Those with mild COVID-19 seek more primary care than uninfected peers – CIDRAP
M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality.
12 May, 2021 | 08:51h | UTCCommentary: People living with HIV more likely to get sick with, die from COVID-19 – Penn State