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Family Medicine

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

21 May, 2021 | 08:24h | UTC

Prevalence of Bacterial Meningitis Among Febrile Infants Aged 29-60 Days With Positive Urinalysis Results: A Systematic Review and Meta-analysis – JAMA Network Open

 

Commentary on Twitter

 


Systematic review: Cognitive behavioral therapy may improve outcomes for autism spectrum disorders.

21 May, 2021 | 08:21h | UTC

Cognitive Behavioral Therapy for Autism Spectrum Disorders: A Systematic Review – Pediatrics (link to abstract – $ for full-text)

 


Cohort study: 14% of adults aged 65 years or less who were infected with SARS-CoV-2 had at least one new type of clinical sequelae that required medical care after the acute phase of the illness.

20 May, 2021 | 08:59h | UTC

Risk of clinical sequelae after the acute phase of SARS-CoV-2 infection: retrospective cohort study – The BMJ

Editorial: Unpacking post-covid symptoms – The BMJ

 

Commentary on Twitter (thread – click for more)

 


FDA In Brief: FDA advises against use of SARS-CoV-2 antibody test results to evaluate immunity or protection from COVID-19, including after vaccination.

20 May, 2021 | 08:55h | UTC

FDA In Brief: FDA Advises Against Use of SARS-CoV-2 Antibody Test Results to Evaluate Immunity or Protection From COVID-19, Including After Vaccination – U.S. Food & Drug Administration

 

Commentary on Twitter (thread – click for more)

 


Systematic review and meta-analysis of observational studies suggest low-dose aspirin may be of benefit for patients with Covid-19 – the finds require further investigation in randomized studies.

20 May, 2021 | 08:54h | UTC

Active Prescription of Low-dose Aspirin During or Prior to Hospitalization and Mortality in COVID-19 — A Systematic Review and Meta-analysis of Adjusted Effect Estimates – International Journal of Infectious Diseases

 


One year after hospital discharge due to SARS-CoV-2 Infection, the prevalence of long-term cough, chest pain, dyspnea, and fatigue was 2.5%, 6.5%, 23.3%, and 61.2%, respectively

20 May, 2021 | 08:57h | UTC

Prevalence of Post-COVID-19 Cough One Year After SARS-CoV-2 Infection: A Multicenter Study – Lung

 


SPRINT Trial final report: targeting a systolic BP of less than 120 mm Hg in patients at increased CV risk is associated with improved CV and mortality outcomes but increases the risk of serious adverse events.

20 May, 2021 | 08:36h | UTC

Final Report of a Trial of Intensive versus Standard Blood-Pressure Control – New England Journal of Medicine

Commentary: Final results of SPRINT study confirm controlling blood pressure critically important in preventing heart disease and stroke – Cleveland Medical Center

 


Characteristics associated with Multisystem Inflammatory Syndrome among adults with SARS-CoV-2 infection

20 May, 2021 | 08:52h | UTC

Characteristics Associated With Multisystem Inflammatory Syndrome Among Adults With SARS-CoV-2 Infection – JAMA Network Open

Editorial: The Multisystem Inflammatory Syndrome in Adults With SARS-CoV-2 Infection—Another Piece of an Expanding Puzzle

Commentary: COVID-related inflammatory syndrome looks different in adults – CIDRAP

 


M-A: Psychologic treatment of depression compared with pharmacotherapy and combined treatment in primary care – Psychotherapy has comparable effects to those of pharmacotherapy, and combined treatment might be better than either psychotherapy or pharmacotherapy alone.

20 May, 2021 | 08:34h | UTC

Psychologic Treatment of Depression Compared With Pharmacotherapy and Combined Treatment in Primary Care: A Network Meta-Analysis – Annals of Family Medicine

Commentary: Combination of psychotherapy and pharmacotherapy more effective in treating depression – American Academy of Family Physicians

 

Commentary on Twitter

https://twitter.com/pimcuijpers/status/1391999860505825286

 


24-week randomized controlled trial: Mixed tree nut snacks resulted in similar weight loss and increased satiety compared to refined carbohydrate snacks in a weight loss and maintenance program.

20 May, 2021 | 08:28h | UTC

Mixed Tree Nut Snacks Compared to Refined Carbohydrate Snacks Resulted in Weight Loss and Increased Satiety during Both Weight Loss and Weight Maintenance: A 24-Week Randomized Controlled Trial – Nutrients

Commentary: Mixed tree nut snacks result in significant weight loss and improved satiety – News Medical

 


ERS clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years.

20 May, 2021 | 08:21h | UTC

European Respiratory Society clinical practice guidelines for the diagnosis of asthma in children aged 5–16 years – European Respiratory Journal

 


WHO and UNICEF launch new tools for the promotion of adolescent mental health.

19 May, 2021 | 08:33h | UTC

News release: WHO and UNICEF launch new tools for the promotion of adolescent mental health – World Health Organization

WHO/UNICEF Helping Adolescents Thrive programme

Helping Adolescents Thrive Toolkit

Magnificent Mei and Friends: Comic 1

The Teacher’s Guide

The mental and brain health of children and adolescents 

 

Commentary on Twitter (thread – click for more)

 


Perspective | Facebook calls links to depression inconclusive. These researchers disagree.

19 May, 2021 | 08:30h | UTC

Facebook Calls Links To Depression Inconclusive. These Researchers Disagree – NPR

Related: Cohort study: Preschoolers’ extensive electronic media use linked to emotional/behavioral issues AND Analysis: Smartphones, Social Media Use and Youth Mental Health AND [Abstract Only] Study: Associations Between Time Spent Using Social Media and Mental Health Problems Among Youth AND Association of Screen Time and Depression in Adolescence AND The Adverse Effects of Social Media use on Young People’s Mental Health May be Caused by Exposure to Cyberbullying, Loss of Sleep, and Reduced Physical Activity AND Research: This Is Your Brain Off Facebook AND Cohort Study: Social Media Use and Adolescent Mental Health AND Supplement: Children, Adolescents and Screens: What We Know and What We Need To Learn

 


The catastrophization effects of an MRI report on the patient and surgeon and the benefits of ‘clinical reporting’: results from an RCT and blinded trials.

19 May, 2021 | 08:25h | UTC

The catastrophization effects of an MRI report on the patient and surgeon and the benefits of ‘clinical reporting’: results from an RCT and blinded trials – European Spine Journal

Related: You cannot unsee your MRI report AND Direct communication between radiologists and patients improves the quality of imaging reports – European Radiology

 

Commentary on Twitter

https://twitter.com/hjluks/status/1392151713700794374

 


Large cohort study confirms the renal toxicities of anti-inflammatories, suggesting Ibuprofen may be the safest option among them.

19 May, 2021 | 08:28h | UTC

Comparative Risks of Nonsteroidal Anti-Inflammatory Drugs on CKD – Clinical Journal of the American Society of Nephrology (link to abstract – $ for full-text)

Commentary: Study: Ibuprofen Found Safest NSAID for the Kidney – MPR

 

Commentary on Twitter

 


SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy.

18 May, 2021 | 07:52h | UTC

SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy – EClinicalMedicine

 


#ACC21 – The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 – “The Lancet women and cardiovascular disease Commission outlines 10 ambitious recommendations to improve health outcomes for millions of women”.

18 May, 2021 | 07:32h | UTC

Homepage: The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030 – The Lancet (free registration required)

Infographic: Women and cardiovascular disease

Video: The Lancet women and cardiovascular disease Commission

News release: Experts call for urgent action to reduce global burden of cardiovascular disease in women by 2030 – The Lancet

 

Commentary on Twitter (thread – click for more)

 


WHO study estimates long working hours causing 745.000 deaths a year from heart disease and stroke.

18 May, 2021 | 07:29h | UTC

News Release: Long working hours increasing deaths from heart disease and stroke: WHO, ILO – World Health Organization

Original Study: Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000–2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury – Environment International

Commentary: Long working hours killing 745,000 people a year, study finds – BBC

 

Commentary on Twitter (thread – click for more)

 


Opinion | E-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth.

18 May, 2021 | 07:28h | UTC

E-Cigarettes and the U.S. Menthol Ban: A Missed Opportunity to Protect Youth – Think Global Health

 

Commentary on Twitter (thread – click for more)

 


Systematic review: Treatment of gastro-esophageal reflux disease to help manage asthma in adults and children may result in reduced use of rescue medications, but the benefits on the number of exacerbations and hospital utilization remain uncertain.

18 May, 2021 | 07:27h | UTC

Pharmacological and surgical interventions for the treatment of gastro‐oesophageal reflux in adults and children with asthma – Cochrane Library

Summary: Treatment of gastro-oesophageal reflux disease to help manage asthma in adults and children – Cochrane Library

 


NICE Guideline Update | Headaches in over 12s: diagnosis and management.

18 May, 2021 | 07:14h | UTC

Headaches in over 12s: diagnosis and management – National Institute for Health and Care Excellence

 


Setting the record straight: There is no ‘Covid heart’.

17 May, 2021 | 08:47h | UTC

Setting the record straight: There is no ‘Covid heart’ – STAT

 

Commentary on Twitter

 


#ACC21 – RCT: No significant differences in cardiovascular events or major bleeding between patients receiving 81 mg vs. 325 mg of aspirin daily.

17 May, 2021 | 08:31h | UTC

Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: High- and Low-Dose Aspirin Equivalent in ASCVD: ADAPTABLE – TCTMD AND Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness – ADAPTABLE – American College of Cardiology

Video: Aspirin Dosing: A Patient-centric Trial Assessing Benefits And Long-term Effectiveness Trial

 


#ACC21 – RCT: Tailored, earlier heart failure rehabilitation program has physical and emotional benefits for older patients.

17 May, 2021 | 08:23h | UTC

Physical Rehabilitation for Older Patients Hospitalized for Heart Failure – New England Journal of Medicine

Commentaries: Tailored, earlier heart failure rehab has physical, emotional benefits for patients – National institutes of Health AND REHAB-HF: Tailored Cardiac Rehab Program Improved Function and Quality of Life in Older HF Patients – American College of Cardiology AND Rehabilitation Therapy in Older Acute Heart Failure Patients – REHAB-HF – American College of Cardiology

Video: A Novel Physical Rehabilitation Intervention For Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Trial

 

Commentaries on Twitter

 


2 recent meta-analysis highlight the benefits of short term (30 days) dual antiplatelet therapy with aspirin + clopidogrel in patients within 24 hours of high-risk transient ischemic attack or mild-moderate ischemic stroke.

17 May, 2021 | 08:16h | UTC

Meta-analysis 1: Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Meta-analysis 2: Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation (link to abstract – $ for full-text)

Commentary: Dual vs. Monotherapy Antiplatelet Agents in Secondary Stroke Prevention – American College of Cardiology

Related Guideline: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

 


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