Family Medicine
Tramadol: Where do we go from here? – “Tramadol’s unpredictability, unique potential harms, and lack of advantage over other opioids or NSAIDs are now well recognized”.
15 Jul, 2021 | 09:14h | UTC[131] Tramadol: Where do we go from here? – Therapeutic Initiative
Cohort study: Increased risk of long-term risk of anemia after bariatric surgery – Compared with the control group, the incidence of anemia was higher in the gastric bypass group (HR 5.05), the vertical-banded gastroplasty group (HR 2.67), and the gastric banding group (HR 2.76).
15 Jul, 2021 | 09:10h | UTCLong-term risk of anaemia after bariatric surgery: results from the Swedish Obese Subjects study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Opinion | The case for mandating COVID-19 vaccines for health care workers.
14 Jul, 2021 | 11:22h | UTCThe Case for Mandating COVID-19 Vaccines for Health Care Workers – Annals of Internal Medicine
News release: Case is strong for mandating COVID-19 vaccination for health care workers – American College of Physicians
Commentary on Twitter
The Case for Mandating COVID-19 Vaccines for Health Care Workers https://t.co/pdaBRZdkfG via @AnnalsofIM "The case for mandating SARS-CoV-2 vaccines for health care workers is substantially stronger than the case was for mandating influenza vaccines." I fully agree.
— Kenny Lin, MD, MPH (@kennylinafp) July 12, 2021
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
14 Jul, 2021 | 11:20h | UTCBetween BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women – JAMA
Commentary: Pfizer COVID vaccine shows 78% efficacy in pregnancy – CIDRAP
Real-World Evidence: The low validity of temperature screening for COVID-19 triage.
14 Jul, 2021 | 11:11h | UTC
Commentary on Twitter
Temperature screening with infrared thermometers has a sensitivity of 9.43% for PCR+ COVID. https://t.co/GjaKpkUqwU
— Carlos del Rio (@CarlosdelRio7) July 7, 2021
New Zealand children falling ill in high numbers due to Covid ‘immunity debt’.
14 Jul, 2021 | 11:16h | UTCNew Zealand children falling ill in high numbers due to Covid ‘immunity debt’ – The Guardian
Related: New Zealand, where Covid-19 is dormant, fights another respiratory virus – The New York Times
One COVID vaccine dose yields good protection in elderly, 2 studies find.
14 Jul, 2021 | 11:15h | UTCOne COVID vaccine dose yields good protection in elderly, 2 studies find – CIDRAP
Commentary on Twitter (thread – click for more)
2 research Articles on #COVID19 vaccine effectiveness in older people:
1) Effectiveness of BNT162b2 and ChAdOx1 nCoV-19 COVID-19 vaccination at preventing hospitalisations in people aged at least 80 years: a test-negative, case-control study https://t.co/ELvMCPwSHF— The Lancet Infectious Diseases (@TheLancetInfDis) June 24, 2021
AAP Technical Report | Prevention of Drowning.
14 Jul, 2021 | 11:09h | UTCPrevention of Drowning – Pediatrics
News releases: American Academy of Pediatrics Identifies Children Most at Risk of Drowning and Recommends Layers of Protection to Prevent Tragedy – American Academy of Pediatrics AND New information, research adds to understanding of drowning risks, precautions – AAP News
Related: The Burden of Unintentional Drowning: Global, Regional and National Estimates of Mortality from the Global Burden of Disease Study AND Preventing drowning: an implementation guide – World Health Organization AND Global report on drowning: preventing a leading killer – World Health Organization AND Report: Open Water Drowning and Risks for Children AND Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update – Wilderness and Environmental Medicine
Commentary on Twitter
Drowning is a leading cause of injury-related death in children. In 2018, almost 900 US children younger than 20 years died from drowning. As educators and advocates, pediatricians can play an important role in #DrowningPrevention: https://t.co/P3eLa1M28p #Pediatrics pic.twitter.com/h3YnqyiMDU
— AAP CME Journals (@AAPJournals) July 13, 2021
WHO: New study highlights unacceptably high global prevalence of syphilis among men who have sex with men.
14 Jul, 2021 | 11:04h | UTCOriginal Study: Prevalence of syphilis among men who have sex with men: a global systematic review and meta-analysis from 2000–20 – The Lancet Global Health
Commentary: Syphilis in men who have sex with men: advancing research and human rights – The Lancet Global Health
Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.
14 Jul, 2021 | 11:07h | UTCNews release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre
Review: Diagnosis, evaluation, and treatment of adenomyosis.
14 Jul, 2021 | 11:01h | UTCDiagnosis, Evaluation, and Treatment of Adenomyosis – JAMA (free for a limited period)
Review: Diagnosis and treatment of alcohol-associated liver disease.
14 Jul, 2021 | 11:02h | UTCDiagnosis and Treatment of Alcohol-Associated Liver Disease: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Treatment of Alcohol-Associated Liver Disease – JAMA
Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.
14 Jul, 2021 | 10:56h | UTCSGLT2 Inhibitors and GLP-1 Receptor Agonists: Indications – American College of Cardiology
Original review: SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications – The Lancet (link to abstract – $ for full-text)
Long Covid: 39% of patients report persistent symptoms more than seven months after diagnosis of COVID-19 in an outpatient setting.
13 Jul, 2021 | 09:57h | UTCCommentaries: Long COVID symptoms in a third of people with COVID-19 – American College of Physicians AND Covid-19: 1-in-3 Patients Reported Long-Hauler Symptoms – Physician’s Weekly
Commentary on Twitter
A new prospective cohort study of >400 people with mild to moderate (outpatient) covid at 7-9 months: nearly 1 of 3 had persistent symptoms #LongCovid @AnnalsofIM
https://t.co/ix1Hhsm0iZ
by @mayssamnehme and colleagues pic.twitter.com/Uc4UEclDvA— Eric Topol (@EricTopol) July 5, 2021
[Preprint] Long Covid: Persistent symptoms following SARS-CoV-2 infection in a random community sample of 508,707 people.
13 Jul, 2021 | 09:55h | UTCCommentary: Study explores the prevalence of long COVID in England – News Medical
Pro-Con Debate | Should we delay covid-19 vaccination in children?
13 Jul, 2021 | 09:51h | UTCShould we delay covid-19 vaccination in children? – The BMJ
News release: Should we delay COVID-19 vaccination in children? – British Medical Journal
Commentary on Twitter
Covid-19 vaccines in adults have been remarkably effective. There is good reason to expect that the same will be true in children.
A group of authors discuss the pros and cons of vaccinating children against covid-19 https://t.co/TOEI67YPeH
— The BMJ (@bmj_latest) July 9, 2021
Podcast | An Antibiotics Primer.
13 Jul, 2021 | 09:35h | UTC#284 An Antibiotics Primer, with @IDdocAdi – The Curbsiders
M-A: Global prevalence of functional constipation according to the Rome criteria.
13 Jul, 2021 | 09:17h | UTC
Commentary on Twitter
New research – Barberio et al – Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysishttps://t.co/pqkXltWnYU#constipation #gitwitter @bribarberio @DrCJudge @EdoardoSavarino @alex_ford12399 pic.twitter.com/NUnZgaVS46
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 4, 2021
New CDC Guidance for COVID-19 prevention in kindergarten schools says safely returning to in-person instruction is a priority.
12 Jul, 2021 | 03:11h | UTCCommentaries: Updated CDC schools guidance prioritizes in-person learning, even if all Covid-19 safety measures aren’t in place – CNN AND The C.D.C. Issues New School Guidance, With Emphasis on Full Reopening – The New York Times AND New CDC guidance says fully vaccinated teachers and students don’t need to wear masks indoors – CNBC AND CDC calls for reopening schools fully, recommends masking – CIDRAP
Related: COVID and schools: the evidence for reopening safely – Nature
[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.
12 Jul, 2021 | 03:12h | UTCCommentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC
Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv
RCT: Another study shows Azithromycin does not improve outcomes in patients with Covid-19.
12 Jul, 2021 | 03:09h | UTCCommentaries: Trial shows that the antibiotic azithromycin does not prevent mild COVID cases progressing to hospitalization, death – European Society of Clinical Microbiology and Infectious Diseases AND Azithromycin: can its benefit be ruled out in mild COVID-19? – The Lancet Respiratory Medicine
Related: M-A: Azithromycin does not reduce the need for invasive mechanical ventilation or mortality in patients with Covid-19. AND RCT: Azithromycin provides no benefit for community treatment of patients with suspected COVID-19 AND RECOVERY trial: Azithromycin not beneficial for patients admitted to hospital with COVID-19 AND [Press release – not published yet] Azithromycin and doxycycline are not generally effective against COVID-19 in patients treated at home, shows PRINCIPLE trial AND Coalition Covid-19 Brazil – Randomized trial: Azithromycin not beneficial for patients admitted to the hospital with severe Covid-19 AND Coalition Covid-19 Brazil – Randomized trial: hydroxychloroquine with or without azithromycin in mild-to-moderate Covid-19
Commentary on Twitter
In patients with mild-to-mod #COVID19 managed without hospital admission, azithromycin + SOC did not reduce the risk of subsequent hospital admission or death
Read the ATOMIC2 trial here https://t.co/QXJ7T08JZS, being presented at #ECCMID2021 by lead author Tim Hinks @HinksLab pic.twitter.com/ZDiPhuQqFB
— The Lancet Respiratory Medicine (@LancetRespirMed) July 9, 2021
Monitoring blood pressure at home: guidance for Canadian patients.
13 Jul, 2021 | 09:15h | UTC
A correlate of protection for SARS-CoV-2 vaccines is urgently needed – “Recent studies suggest that neutralizing antibodies could serve as a correlate of protection for vaccines against SARS-CoV-2 in humans”.
12 Jul, 2021 | 03:03h | UTCA correlate of protection for SARS-CoV-2 vaccines is urgently needed – Nature Medicine
Pfizer says it’s time for a Covid booster; FDA and CDC say not so fast.
12 Jul, 2021 | 03:08h | UTCPfizer says it’s time for a Covid booster; FDA and CDC say not so fast – CNN
See also: CDC, FDA contradict Pfizer on COVID-19 vaccine booster – CIDRAP AND Do I need a COVID-19 booster shot? 6 questions answered on how to stay protected – The Conversation AND Pfizer suggests booster shots will be needed this year, but government officials say science will dictate the timing – The Washington Post AND Pfizer to seek OK for 3rd vaccine dose; shots still protect – Associated Press AND Citing the Delta Variant, Pfizer Will Pursue Booster Shots and a New Vaccine – The New York Times (a few articles per month are free) AND Question open on need for COVID booster shot, data awaited, WHO says – Reuters
Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report.
12 Jul, 2021 | 01:41h | UTC