Open access
Open access
Powered by Google Translator Translator

Family Medicine

Extended intervals and extra doses of the AstraZeneca vaccine are associated with increased immunogenicity.

7 Sep, 2021 | 10:56h | UTC

Reactogenicity and immunogenicity after a late second dose or a third dose of ChAdOx1 nCoV-19 in the UK: a substudy of two randomised controlled trials (COV001 and COV002) – The Lancet

Invited commentary: Longer intervals and extra doses of ChAdOx1 nCoV-19 vaccine

 

Commentaries on Twitter

(thread – click for more)

(thread – click for more)

 

Opinion | Liquid biopsy: misplaced faith in early cancer detection?

7 Sep, 2021 | 21:30h | UTC

Liquid biopsy: misplaced faith in early cancer detection? – STAT

 

Commentary on Twitter

 

Defining pediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement.

7 Sep, 2021 | 21:26h | UTC

Defining paediatric metabolic (dysfunction)-associated fatty liver disease: an international expert consensus statement – The Lancet Gastroenterology & Hepatology (free registration required)

 

Commentary on Twitter

 

Antibiotics use is linked to increased risk of subsequent colorectal cancer.

7 Sep, 2021 | 21:25h | UTC

Antibiotics Use and Subsequent Risk of Colorectal Cancer: A Swedish Nationwide Population-Based Study – JNCI: Journal of the National Cancer Institute

Commentaries:

Antibiotics linked to increased risk of colon cancer – Umea University

Study links antibiotics use and increased subsequent risk of colorectal cancer – MedicalResearch.com

 

[Preprint] Large cohort study in Brazil showed AstraZeneca vaccine had high overall effectiveness against severe disease to individuals up to 89 years of age. In comparison, CoronaVac had high overall effectiveness against severe disease in individuals up to 79 years.

7 Sep, 2021 | 10:54h | UTC

Influence of age on the effectiveness and duration of protection in Vaxzevria and CoronaVac vaccines – medRxiv

 

Opinion | Video: Immunity is the only way through a pandemic (w/Dr. Monica Gandhi).

7 Sep, 2021 | 10:45h | UTC

Immunity Is The Only Way Through A Pandemic (w/Dr. Monica Gandhi) – ZDoggMD

 

CDC report: Hospitalization rates for Covid-19 were 10 times higher among unvaccinated than among fully vaccinated adolescents.

7 Sep, 2021 | 10:52h | UTC

Hospitalizations Associated with COVID-19 Among Children and Adolescents — COVID-NET, 14 States, March 1, 2020–August 14, 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

More kids hospitalized with Covid-19 in states with lower vaccination rates, CDC report finds – CNN

The hospitalization rate among teens who are unvaccinated is 10 times higher than teens who are vaccinated, new CDC data shows – Insider

Child COVID hospital cases up in low-vaccination states – CIDRAP

 

Commentary on Twitter

 

Tube feeding for people with severe dementia: making decisions.

7 Sep, 2021 | 10:39h | UTC

Tube feeding for people with severe dementia: making decisions – Evidently Cochrane

Original article: Systematic review: Enteral tube feeding for people with severe dementia – “We found no evidence that tube feeding improves survival; improves quality of life; reduces pain; reduces mortality; decreases behavioural and psychological symptoms of dementia”.

 

Podcast: Febrile Infants (based on the new AAP Guideline).

7 Sep, 2021 | 10:31h | UTC

#33: Febrile Infants – When Babies Are Too Hot – The Cribsiders

Original guideline:

AAP Guideline: Evaluation and management of well-appearing febrile infants 8 to 60 days old.

Commentaries:

Landmark Febrile Neonate, Febrile Infant Guideline from the AAP – JournalFeed

Small Talk – Hot Off The Presses: The Latest AAP Guidelines for the Febrile Neonate – emDocs

Related:

M-A: Low prevalence of bacterial meningitis among well-appearing febrile infants aged 29-60 days with positive urinalysis results – “These results suggest that for these infants, the decision to use lumbar puncture should not be guided by urinalysis results alone”.

Things We Do for No Reason: Lumbar Punctures in Low-Risk Febrile Infants with Bronchiolitis

[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis

Study: Clinical Prediction Rule to Identify Febrile Infants at Low Risk for Serious Bacterial Infections

Cohort Study: Accuracy of Complete Blood Cell Counts to Identify Febrile Infants 60 Days or Younger With Invasive Bacterial Infections

 

Podcast: The Best of Liver Tests.

7 Sep, 2021 | 10:29h | UTC

#293 The Best of Liver Tests with Dr. Elliot Tapper – The Curbsiders

 

The resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce; vaccine effectiveness against infection was reduced from above 90% from March through June to 65% in July.

6 Sep, 2021 | 11:09h | UTC

Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce – New England Journal of Medicine

Related:

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.

 

Commentary on Twitter (thread – click for more)

 

Large surveillance study finds severe adverse events after COVID-19 mRNA vaccination are rare.

6 Sep, 2021 | 11:02h | UTC

Surveillance for Adverse Events After COVID-19 mRNA Vaccination – JAMA

Editorial: Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink – JAMA

Commentaries:

mRNA COVID vaccines not tied to serious side effects – CIDRAP

Researchers find no serious health effects linked to mRNA COVID-19 vaccines – News Medical

 

Commentary on Twitter

 

Systematic review: evaluation of dietary patterns and all-cause mortality.

6 Sep, 2021 | 10:43h | UTC

Evaluation of Dietary Patterns and All-Cause Mortality: A Systematic Review – JAMA Network Open

 

Commentary on Twitter (thread – click for more)

 

Interactive infographic showing the effects of Delta: How coronavirus spreads through a population and how we can beat it.

6 Sep, 2021 | 10:59h | UTC

How coronavirus spreads through a population and how we can beat it – The Guardian

 

Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study.

6 Sep, 2021 | 10:36h | UTC

Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: Can We Detect Central Vertigo on Exam? – Journal Feed

 

M-A: Effect of monthly injections of naltrexone on alcohol consumption.

6 Sep, 2021 | 10:39h | UTC

Effect of extended-release naltrexone on alcohol consumption: a systematic review and meta-analysis – Addiction (link to abstract – $ for full-text)

 

Double vaccination halves risk of Long COVID.

3 Sep, 2021 | 10:29h | UTC

News release: Double vaccination halves risk of Long COVID – King’s College London

Original study: Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study – The Lancet Infectious Diseases

Commentaries:

Largest study of its kind finds face masks reduce COVID-19 – University of California – Berkeley

Study: Vaccines slash long-haul COVID, hospital rates – CIDRAP

Vaccination reduces risk of long Covid, even when people are infected, U.K. study indicates – STAT

Being fully vaccinated reduces odds of long-term Covid-19 symptoms by half, UK study suggests – CNN

Coronavirus vaccines cut risk of long Covid, study finds – BBC

Related: M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter

 

[Preprint] Largest study of masks yet details their importance in fighting Covid-19.

3 Sep, 2021 | 10:30h | UTC

Largest study of masks yet details their importance in fighting Covid-19 – NBC News

Original study: The Impact of Community Masking on COVID-19: A Cluster-Randomized Trial in Bangladesh – Innovations for Poverty Action

See also: A Study In Bangladesh Tripled The Rate Of Mask-Wearing. Can It Help In The U.S.? – NPR

 

Commentaries on Twitter (thread – click for more)

(thread from the author – click for more)

 

EU agency says to focus on vaccines first not booster shots.

3 Sep, 2021 | 10:34h | UTC

EU agency says to focus on vaccines first not booster shots – Associated Press

See also: European officials say COVID-19 booster isn’t urgent – CIDRAP

 

Opinion | “The downsides of masking young students are real”.

3 Sep, 2021 | 10:24h | UTC

The Downsides of Masking Young Students Are Real – The Atlantic

 

Commentary with a rebuttal on Twitter (thread – click for more)

 

Review: Cardiovascular care of older adults.

3 Sep, 2021 | 10:13h | UTC

Cardiovascular care of older adults – The BMJ

 

AAP Guideline: Long-term follow-up care for childhood, adolescent, and young adult cancer survivors.

3 Sep, 2021 | 10:17h | UTC

Long-term Follow-up Care for Childhood, Adolescent, and Young Adult Cancer Survivors – Pediatrics

News release: American Academy of Pediatrics Offers Guidance for Caring and Treatment of Long-Term Cancer Survivors – American Academy of Pediatrics

 

Position Paper: Diagnosis and management of heart failure in elderly patients from hospital admission to discharge.

3 Sep, 2021 | 10:11h | UTC

Diagnosis and Management of Heart Failure in Elderly Patients from Hospital Admission to Discharge: Position Paper – Journal of Clinical Medicine

 

Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.

2 Sep, 2021 | 10:10h | UTC

Long COVID – the physical and mental health of children and non-hospitalised young people 3 months after SARS-CoV-2 infection; a national matched cohort study (The CLoCk) Study.

Commentaries:

Long Covid in children ‘nowhere near scale feared’ – BBC

Long covid: One in seven children may still have symptoms 15 weeks after infection, data show – The BMJ

Related:

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

Cohort study: Risk factors for long covid in previously hospitalized children.

M-A: More than 50 long-term effects of COVID-19.

 

Commentary on Twitter (thread – click for more)

 

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

2 Sep, 2021 | 10:05h | UTC

Waning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar – medRxiv

Related:

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

Pfizer says it’s time for a Covid booster; FDA and CDC say not so fast.

 

Commentary on Twitter (thread – click for more)

 

Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.