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M-A of randomized trials: Efficacy of exercise combined with standard treatment for depression compared to standard treatment alone.

28 Sep, 2021 | 08:55h | UTC

Efficacy of exercise combined with standard treatment for depression compared to standard treatment alone: A systematic review and meta-analysis of randomized controlled trials – Journal of Affective Disorders

 

Commentary on Twitter

 


Improving communication of incidental imaging findings: transforming uncertainty into opportunity.

28 Sep, 2021 | 08:50h | UTC

Improving Communication of Incidental Imaging Findings: Transforming Uncertainty Into Opportunity – Mayo Clinic Proceedings

Related:

Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults

Review: Prevalence and Outcomes of Incidental Imaging Findings

Study: Cascades of Care After Incidental Findings

 


Updated WHO Living Guideline: Therapeutics and COVID-19.

26 Sep, 2021 | 22:16h | UTC

Therapeutics and COVID-19: living guideline – World Health Organization

WHO Statement: On new recommendation for treatment of COVID-19 patients: WHO calls for equitable access to casirivimab and imdevimab for COVID-19

See also:

WHO recommends antibody treatment for COVID patients at high risk of hospital admission.

Antibody and cellular therapies for treatment of covid-19: a living systematic review and network meta-analysis – The BMJ

Commentary: WHO adds new recommendation for COVID-19 monoclonal antibody combo – CIDRAP

 


CDC Report: Schools without mask requirements were more likely to have Covid-19 outbreaks.

26 Sep, 2021 | 22:10h | UTC

Association Between K–12 School Mask Policies and School-Associated COVID-19 Outbreaks — Maricopa and Pima Counties, Arizona, July–August 2021 – CDC Morbidity and Mortality Weekly Report

Commentary: Schools Without Mask Requirements More Likely to See COVID-19 Outbreaks – U.S. News

 

Commentary on Twitter

 


Consensus Statement: Paracetamol use during pregnancy — a call for precautionary action – “Pregnant women should minimize risk by using the lowest effective APAP dose for the shortest possible time”.

26 Sep, 2021 | 22:02h | UTC

Paracetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology

Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology

Commentaries:

New research cautions about possible risks of acetaminophen use during pregnancy – STAT

Expert reaction to statement on paracetamol use during pregnancy – Science Media Centre

A Common Pain Relief Med Used in Pregnancy Should Be Taken with Caution, Experts Warn – ScienceAlert

Scientists suggest pregnant women only take paracetamol/acetaminophen if medically necessary – MedicalXpress

 

Commentary on Twitter

 


Less common bacterial, fungal and viral infections: review of management in the pregnant patient.

26 Sep, 2021 | 21:38h | UTC

Less common bacterial, fungal and viral infections: review of management in the pregnant patient – Drugs in Context

 


[Preprint] PRINCIPLE RCT: Colchicine does not improve time to recovery in outpatients with Covid-19 at higher risk of complications.

24 Sep, 2021 | 10:13h | UTC

Colchicine for COVID-19 in adults in the community (PRINCIPLE): a randomised, controlled, adaptive platform trial – medRxiv

Related: COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.

 

Commentary on Twitter

 


No, vaccinated people are not ‘just as likely’ to spread the Coronavirus as unvaccinated people.

24 Sep, 2021 | 10:06h | UTC

No, Vaccinated People Are Not ‘Just as Likely’ to Spread the Coronavirus as Unvaccinated People – The Atlantic

 

Commentary on Twitter

 


Expert panel recommends against use of race in assessment of kidney function.

24 Sep, 2021 | 09:01h | UTC

Expert panel recommends against use of race in assessment of kidney function – STAT

Original Guidance: A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease – American Journal of Kidney Diseases

 

Commentary on Twitter

 


Landmark articles suggest eliminating race in the estimation of kidney function.

24 Sep, 2021 | 09:03h | UTC

Editorial: Time to Eliminate Health Care Disparities in the Estimation of Kidney Function – New England Journal of Medicine

Study 1: New Creatinine- and Cystatin C–Based Equations to Estimate GFR without Race – New England Journal of Medicine

Study 2: Race, Genetic Ancestry, and Estimating Kidney Function in CKD – New England Journal of Medicine

Commentaries:

NIH-supported study suggests alternative to race-based kidney function calculations – NIH News Releases

Remove Race From Equation Used to Assess Kidney Function, Researchers Say – AJMC

Researchers identify potential approach to eliminate race from equations to estimate kidney function – News Medical

 

Commentary on Twitter

 


RCT confirms antibiotics are not needed for most children with uncomplicated lower respiratory tract infection if pneumonia is not suspected clinically.

24 Sep, 2021 | 09:00h | UTC

Antibiotics for lower respiratory tract infection in children presenting in primary care in England (ARTIC PC): a double-blind, randomised, placebo-controlled trial – The Lancet

 

Commentary on Twitter

 


Cohort Study: Insulin resistance linked to increased risk of major depressive disorder.

24 Sep, 2021 | 08:59h | UTC

Incident Major Depressive Disorder Predicted by Three Measures of Insulin Resistance: A Dutch Cohort Study – The American Journal of Psychiatry

Commentaries:

Insulin Levels, BMI in Youth May Be Linked to Psychosis, Depression Risk in Adulthood – Psychiatric News

Insulin Resistance Linked to Major Depressive Disorder, Dutch Study Finds – Psychiatric News Alert

Insulin resistance doubles risk of major depressive disorder – Stanford Medicine

 


WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18 – In many countries, ciprofloxacin resistance was exceedingly high, and decreased susceptibility or resistance to ceftriaxone and cefixime continued to emerge.

24 Sep, 2021 | 08:53h | UTC

WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18: a retrospective observational study – The Lancet Microbe

 


Large, multinational cohort suggests ondansetron use in pregnancy does not increase the risk for adverse fetal outcomes.

24 Sep, 2021 | 08:57h | UTC

Comparison of Pregnancy Outcomes of Patients Treated With Ondansetron vs Alternative Antiemetic Medications in a Multinational, Population-Based Cohort – JAMA Network Open

Editorial: Providing Data to Empower Pregnant Patients to Make Evidence-Based Choices

Related: Cohort Study: Maternal Ondansetron Use and Risk of Cardiac Malformations and Oral Clefts in Offspring

 

Commentary on Twitter

 


European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients.

24 Sep, 2021 | 08:54h | UTC

European guideline on indications, performance, and clinical impact of hydrogen and methane breath tests in adult and pediatric patients: European Association for Gastroenterology, Endoscopy and Nutrition, European Society of Neurogastroenterology and Motility, and European Society for Paediatric Gastroenterology Hepatology and Nutrition consensus- UEG Journal

 


[Preprint] Third dose of Sinopharm inactivated SARS-CoV-2 vaccine induces robust B and T cell responses.

23 Sep, 2021 | 10:18h | UTC

Robust induction of B cell and T cell responses by a third dose of inactivated SARS-CoV-2 vaccine – medRxiv

Commentaries:

Three doses of inactivated BBIBP-CorV SARS-CoV-2 vaccine induce robust B and T cell responses – News Medical

Sinopharm’s COVID booster reverses antibody decline, enhances cell-based responses – study – Reuters

 


Cochrane Special Collection | De-implementation of low-value health care: resource prioritization in the COVID-19 pandemic era.

23 Sep, 2021 | 10:13h | UTC

De-implementation of low-value health care: resource prioritization in the COVID-19 pandemic era – Cochrane Library

Editorial: Making wise choices about low‐value health care in the COVID‐19 pandemic – Cochrane Library

Commentary: Choosing health care wisely when resources are scarce – Evidently Cochrane

 

Commentaries on Twitter

 


Randomized phase 1/2 trial: Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in children and adolescents aged 3–17 years.

23 Sep, 2021 | 10:16h | UTC

Safety and immunogenicity of an inactivated COVID-19 vaccine, BBIBP-CorV, in people younger than 18 years: a randomised, double-blind, controlled, phase 1/2 trial – The Lancet Infectious Diseases

Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years.

 


Systematic review: Clinical characteristics of multisystem inflammatory syndrome in adults.

23 Sep, 2021 | 10:12h | UTC

Clinical Characteristics of Multisystem Inflammatory Syndrome in Adults: A Systematic Review – JAMA Network Open

 

Commentary on Twitter

 


AHA Scientific Statement: Sleep‐disordered breathing and cardiovascular disease in children and adolescents.

23 Sep, 2021 | 10:02h | UTC

Sleep‐Disordered Breathing and Cardiovascular Disease in Children and Adolescents: A Scientific Statement From the American Heart Association – Journal of the American Heart Association

News release: Obstructive sleep apnea is common in kids and may impact blood pressure, heart health – American Heart Association

 


Importance of distinguishing between asthma and chronic obstructive pulmonary disease in primary care.

23 Sep, 2021 | 09:57h | UTC

Importance of distinguishing between asthma and chronic obstructive pulmonary disease in primary care – Canadian Family Physician

 


[Press release – not published yet] J&J says booster shot at two months provided 75% protection against moderate to severe COVID-19 globally and 94% of such cases in the U.S.

22 Sep, 2021 | 10:26h | UTC

Press release: Johnson & Johnson Announces Real-World Evidence and Phase 3 Data Confirming Strong and Long-Lasting Protection of Single-Shot COVID-19 Vaccine in the U.S.

Commentaries:

Johnson & Johnson says additional dose boosts Covid vaccine efficacy – STAT

J&J booster 94% effective against severe COVID, company says – CIDRAP

Two dose version of Johnson & Johnson shot 94% effective against Covid-19, study finds – CNN

 

Commentaries on Twitter

(thread – click for more)

(thread – click for more)

https://twitter.com/hildabast/status/1440363761299124229

 


Interpreting SARS-CoV-2 Test Results.

22 Sep, 2021 | 10:24h | UTC

Interpreting SARS-CoV-2 Test Results – JAMA

 


Long Covid – The illness narratives.

22 Sep, 2021 | 10:19h | UTC

Long Covid – The illness narratives – Social Science & Medicine

 

Commentary on Twitter

https://twitter.com/trishgreenhalgh/status/1439199576158883843

 


AHA Scientific Statement: Weight-loss strategies for prevention and treatment of hypertension.

22 Sep, 2021 | 10:09h | UTC

Weight-Loss Strategies for Prevention and Treatment of Hypertension: A Scientific Statement From the American Heart Association – Hypertension

News release: Weight-loss meds, surgery could fight obesity-related high blood pressure – American Heart Association

 


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