Family Medicine
Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.
18 Jan, 2022 | 09:44h | UTCPost-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine
Podcast: Lower Extremity Edema Pearls.
18 Jan, 2022 | 09:33h | UTC#316 Lower Extremity Edema – The Curbsiders
Association of hormonal contraceptive use with adverse health outcomes: an umbrella review of meta-analyses of randomized clinical trials and cohort studies.
18 Jan, 2022 | 09:29h | UTC
A national cohort study in Sweden showed pregnancy complications (preeclampsia or eclampsia, gestational hypertension, gestational diabetes, preterm birth, small for gestational age, and stillbirth) are associated with increased risk of cardiovascular disease later in life.
18 Jan, 2022 | 09:26h | UTC
Cohort study: In patients who underwent bariatric surgery, those submitted to gastric bypass were slightly more likely to remain free of obesity-related medications during follow-up compared with those who underwent sleeve gastrectomy.
18 Jan, 2022 | 09:31h | UTCMedication Use for Obesity-Related Comorbidities After Sleeve Gastrectomy or Gastric Bypass – JAMA Surgery (link to abstract – $ for full-text)
Commentary: Gastric Bypass Tied to Modest Shift in Need for Comorbidity Meds – MedPage Today (free registration required)
Commentary on Twitter
Among patients taking medications for obesity-related conditions before bariatric surgery, gastric bypass and sleeve gastrectomy both had high rates of medication discontinuation after surgery, however gastric bypass was slightly more effective. https://t.co/JrIaYk9dZT pic.twitter.com/BAbaGINCpb
— JAMA Surgery (@JAMASurgery) January 12, 2022
Viewpoint: COVID-19 therapeutics for nonhospitalized patients.
17 Jan, 2022 | 00:31h | UTCCOVID-19 Therapeutics for Nonhospitalized Patients – JAMA
Editorial: Realizing the Potential of Anti–SARS-CoV-2 Monoclonal Antibodies for COVID-19 Management – JAMA
Hospital admissions from childhood common infections were largely reduced in England during the pandemic due to control measures for Covid-19.
17 Jan, 2022 | 00:37h | UTCEditorial: Covid-19 control measures and common paediatric infections – The BMJ
News Release: Dramatic fall in hospital admissions for child infections during first year of covid-19 pandemic – BMJ
2022 Guidelines on the management of chronic venous disease of the lower limbs.
16 Jan, 2022 | 23:22h | UTC
RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.
16 Jan, 2022 | 23:13h | UTCThe D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
Multi-Disciplinary Guideline: Management of nephrolithiasis in pregnancy.
16 Jan, 2022 | 23:17h | UTC
Commentary from the author on Twitter
https://t.co/bFtOYFgBmr Started as an assigned resident presentation. Turned into a set of multi-d guidelines implemented at the university level. Now published for all to reference! Thank you all authors for input & guidance @peepeeDoctor @willrobe1 @amy_krambeck @sapanambani
— Matthew Lee (@MSLee_MD) December 23, 2021
RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.
16 Jan, 2022 | 23:11h | UTCNews Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.
16 Jan, 2022 | 22:53h | UTCCommentaries:
Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University
Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay
Cluster randomized trial: no added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis.
16 Jan, 2022 | 22:59h | UTC
Analysis: Sarcopenia: early prevention or overdiagnosis?
16 Jan, 2022 | 22:48h | UTCSarcopenia: early prevention or overdiagnosis? – The BMJ
Related: Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary. (several articles on the subject)
Commentary from the author on Twitter
We have a new diagnosis! 2 billion people may turn into patients with sarcopenia. Despite no evidence to justify why we should diagnose elderly people. My latest article in @bmj_latest with @drjohnbrodersen and JBülow. #overdiagnosis #sarcopenia #EBM https://t.co/mNFxmuz4U1
— Christoffer Bjerre Haase (@BjerreHaase) January 13, 2022
Assessment and treatment of thyroid disorders in pregnancy and the postpartum period.
16 Jan, 2022 | 22:42h | UTCAssessment and treatment of thyroid disorders in pregnancy and the postpartum period – Nature Reviews Endocrinology (if the link is paywalled, try this one)
Commentary on Twitter
New content online: Assessment and treatment of thyroid disorders in pregnancy and the postpartum period https://t.co/KrXeocu8sd pic.twitter.com/HeSCXNkelb
— Nature Reviews Endocrinology (@NatureRevEndo) January 4, 2022
New UK Guidance: Self-isolation for those with COVID-19 can end after 5 full days following 2 negative rapid lateral flow tests – “The default self-isolation period continues to be 10 days, and you may only leave self-isolation early if you have taken 2 rapid lateral flow tests and do not have a temperature in line with guidance”.
14 Jan, 2022 | 08:48h | UTC
Commentary on Twitter (thread – click for more)
Self-isolation period for people infected with COVID in England will be reduced to 5 days from Monday 17 Jan. But it's conditional: 2 NEGATIVE tests on days 5 & 6, & no symptoms, & not in certain high risk situations e.g. working with vulnerable people
1/https://t.co/HLxlIbpbkR— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) January 13, 2022
Unvaccinated pregnant people are at higher risk for Covid complications and newborn deaths.
14 Jan, 2022 | 08:44h | UTCUnvaccinated pregnant people are at higher risk for Covid complications and newborn deaths – STAT
Original Study: SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland – Nature Medicine
COVID vaccines safely protect pregnant people: the data are in.
14 Jan, 2022 | 08:43h | UTCCOVID vaccines safely protect pregnant people: the data are in – Nature
Related:
COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.
Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.
AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.
Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.
5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.
CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
Fluvoxamine for Covid-19: What Prescribers and Pharmacists Need to Know.
14 Jan, 2022 | 08:37h | UTCFluvoxamine: What Prescribers and Pharmacists Need to Know – Covid-19 Advisory for Ontario
Related:
Fluvoxamine for the early treatment of SARS-CoV-2 Infection: a review of current evidence.
Commentary on Twitter
Thinking of prescribing fluvoxamine for covid 19? Ontario has a nice infographichttps://t.co/MKT8PqlJpM
— Todd C. Lee (@DrToddLee) January 12, 2022
Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.
14 Jan, 2022 | 08:39h | UTCRelated:
Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery
BJS commission on surgery and perioperative care post-COVID-19.
ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.
Position statement: Perioperative management of post-COVID-19 surgical patients.
Perspective: Omicron is forcing us to rethink mild COVID.
14 Jan, 2022 | 08:30h | UTCOmicron Is Forcing Us to Rethink Mild COVID – The Atlantic
RCT: Colchicine did not significantly reduce the need for intubation or 28-day mortality in patients hospitalized with Covid-19.
14 Jan, 2022 | 08:35h | UTCRelated:
M-A: Colchicine doesn’t lessen COVID-19 severity or stave off risk of death.
Commentary on Twitter
This randomized clinical trial found that colchicine did not significantly reduce mechanical ventilation or mortality in patients hospitalized with #COVID19 pneumonia. @DLBhattMD https://t.co/2nU5Ks74uF pic.twitter.com/VvHhTFnBhV
— JAMA Network Open (@JAMANetworkOpen) December 29, 2021
Review: Migraine.
14 Jan, 2022 | 08:16h | UTCMigraine – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Migraine (if the link is paywalled, try this one)
M-A: Combined oral contraceptives may improve overall premenstrual symptomatology but are not helpful for premenstrual depressive symptoms.
14 Jan, 2022 | 07:49h | UTCCommentary: ‘Optimal’ treatment for premenstrual depressive symptoms remains elusive – Healio (free registration required)
Observational study in adolescents showed the Pfizer-BioNTech vaccine had an overall effectiveness of 94% against hospitalization and 98% against critical Covid-19.
13 Jan, 2022 | 09:00h | UTCEditorial: Sparing of Severe Covid-19 in Vaccinated Adolescents – New England Journal of Medicine