Evidence-based Medicine
Opinion | Regression towards the mean—a plea for civility in peer review.
2 Dec, 2022 | 14:22h | UTCOpinion: Regression towards the mean—a plea for civility in peer review – The BMJ
Predatory conferences: a systematic scoping review.
2 Dec, 2022 | 14:17h | UTCPredatory conferences: a systematic scoping review – BMJ Open
BMJ Investigation | FDA oversight of clinical trials is “grossly inadequate,” say experts.
25 Nov, 2022 | 12:35h | UTCFDA oversight of clinical trials is “grossly inadequate,” say experts – The BMJ
News Release: Investigation raises concerns about poor FDA oversight of clinical trials – BMJ Newsroom
Commentary: FDA Oversight of Clinical Trials Described as ‘Grossly Inadequate’ – HealthDay
Brief Review | Core outcome sets in medical research.
25 Nov, 2022 | 12:22h | UTCCore outcome sets in medical research – BMJ Medicine
Commentary on Twitter
This article sets out the principles of why core outcome sets are needed and provides some information on how medical researchers can select and appraise existing core outcomes. ▶️ https://t.co/LZineBD47F#MedTwitter pic.twitter.com/U1RrIYQBY2
— BMJMedicine (@BMJMedicine) November 17, 2022
Guide to statistics and methods | Adjustment for baseline characteristics in randomized clinical trials.
21 Nov, 2022 | 14:05h | UTCAdjustment for Baseline Characteristics in Randomized Clinical Trials – JAMA (free for a limited period)
Commentary: Should you adjust for baseline characteristics within randomized controlled trials? – Healthcare Economist
Consistency between trials presented at conferences, their subsequent publications and press releases.
17 Nov, 2022 | 12:19h | UTC
Perspective | Teaching a deeper understanding of the medical literature.
4 Nov, 2022 | 13:26h | UTCTeaching a Deeper Understanding of the Medical Literature – Journal of General Internal Medicine
Opinion | Heterogeneity in pragmatic randomized trials: sources and management.
1 Nov, 2022 | 12:08h | UTCHeterogeneity in pragmatic randomised trials: sources and management – BMC Medicine
AHA Scientific Statement | Physician wellness in academic cardiovascular medicine.
27 Oct, 2022 | 12:34h | UTCTop Things to Know: Physician Wellness in Academic CV Medicine – American Heart Association
Commentaries:
Physician Wellness in Academic Cardiovascular Medicine: Key Points – American College of Cardiology
Perspective | Reducing bureaucracy in clinical trials.
18 Oct, 2022 | 12:41h | UTCReducing bureaucracy in clinical trials – UEG Journal
Interpreting and assessing confidence in network meta-analysis results: an introduction for clinicians.
18 Oct, 2022 | 12:39h | UTC
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study.
17 Oct, 2022 | 12:39h | UTCSee also:
Homepage: The Burden of Proof Studies – Nature Medicine
The Burden of Proof studies: assessing the evidence of risk
Health effects associated with vegetable consumption: a Burden of Proof study
Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study
Health effects associated with smoking: a Burden of Proof study
Commentary on Twitter
Using the Burden of Proof analytical tool, a meta-analysis found weak or no evidence of associations between unprocessed #redmeat consumption and increased risk of six #cardiometabolic disease and #cancer outcomes. @IHME_UW https://t.co/3b7Sa9zCA1
— Nature Medicine (@NatureMedicine) October 10, 2022
Health effects associated with vegetable consumption: a Burden of Proof study.
17 Oct, 2022 | 12:40h | UTCHealth effects associated with vegetable consumption: a Burden of Proof study – Nature Medicine
See also:
Homepage: The Burden of Proof Studies – Nature Medicine
The Burden of Proof studies: assessing the evidence of risk
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study
Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study
Health effects associated with smoking: a Burden of Proof study
Commentary on Twitter
A meta-analysis using the Burden of Proof function identified modest evidence supporting a protective role of #vegetable consumption and #ischemicheartdisease, #stroke and esophageal cancer, but not type 2 #diabetes. @IHME_UW https://t.co/1w8OAELSvU
— Nature Medicine (@NatureMedicine) October 10, 2022
Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study.
17 Oct, 2022 | 12:37h | UTCSee also:
Homepage: The Burden of Proof Studies – Nature Medicine
The Burden of Proof studies: assessing the evidence of risk
Health effects associated with vegetable consumption: a Burden of Proof study
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study
Health effects associated with smoking: a Burden of Proof study
Commentary on Twitter
A systematic review using the Burden of Proof meta-analytic method found a significant harmful effect between high systolic #bloodpressure and #ischemicheartdisease. @IHME_UW https://t.co/hewQ9nsCTh
— Nature Medicine (@NatureMedicine) October 10, 2022
Health effects associated with smoking: a Burden of Proof study.
17 Oct, 2022 | 12:36h | UTCHealth effects associated with smoking: a Burden of Proof study – Nature Medicine
See also:
Homepage: The Burden of Proof Studies – Nature Medicine
The Burden of Proof studies: assessing the evidence of risk
Health effects associated with vegetable consumption: a Burden of Proof study
Health effects associated with consumption of unprocessed red meat: a Burden of Proof study
Effects of elevated systolic blood pressure on ischemic heart disease: a Burden of Proof study
Commentary on Twitter
A meta-analysis using the Burden of Proof method reported consistent evidence supporting harmful associations between #smoking and 28 different #health outcomes. @IHME_UW https://t.co/0tEnMvTwG6
— Nature Medicine (@NatureMedicine) October 10, 2022
Participation of older adults in clinical trials for new drug applications and biologics license applications from 2010-2019.
17 Oct, 2022 | 12:12h | UTC
Commentary on Twitter
Underrepresentation of adults above age 75-80 years found in evaluation of new medications. 60-75 year-olds were reasonably well represented in clinical trials in proportion to the prevalence data in the US. #OAResearch https://t.co/2RL5fTo3LA
— JAMA Network Open (@JAMANetworkOpen) October 14, 2022
Randomized controlled trials in de-implementation research: a systematic scoping review.
7 Oct, 2022 | 14:14h | UTC
Commentary from the authors on Twitter:
(thread – click for more)
https://twitter.com/KariTikkinen/status/1576615329106522112
(thread – click for more)
https://twitter.com/AleksiRaudasoja/status/1576840519598362625
Systematic Review | Randomized clinical trials of machine learning interventions in health care.
30 Sep, 2022 | 12:37h | UTC
Good publication practice guidelines for company-sponsored biomedical research.
27 Sep, 2022 | 13:12h | UTC
Commentary on Twitter
New from @ISMPP: new updated guidelines for publishing company-sponsored biomedical research include guidance on transparency and accountability, two increasingly high priorities for these studies: https://t.co/zcjIn40Uki pic.twitter.com/ygOv0nBMLn
— Annals of Int Med (@AnnalsofIM) August 30, 2022
Perspective | Ensuring an accurate scientific record in an era of pre-print servers.
1 Sep, 2022 | 11:38h | UTC
Perpetual Observational Studies | New strategies to support efficient implementation of observational studies and randomized trials in infectious diseases.
26 Aug, 2022 | 13:17h | UTC
Editorial | Keeping meta-analyses fresh.
25 Aug, 2022 | 12:09h | UTCKeeping Meta-analyses Fresh – JAMA Network Open
Evaluating how clear the questions being investigated in randomized trials are: systematic review of estimands.
24 Aug, 2022 | 13:59h | UTC
Commentary from the author Twitter (thread – click for more)
Are randomised trials answering clear & useful questions? We conducted this review of published trials to find out https://t.co/ZO2GacCZ90 @bmj_latest pic.twitter.com/r9VXYvpHRX
— Suzie Cro (@Suzie_cro) August 23, 2022
Using individual participant data to improve network meta-analysis projects.
24 Aug, 2022 | 14:00h | UTC
Commentary on Twitter
Using individual participant data to improve network meta-analysis projects
All the details are explained by @Richard_D_Riley and colleagues.#OpenAccess
? https://t.co/r0wdeK6jmd pic.twitter.com/jKp4Z2VklK
— BMJ Evidence-Based Medicine (@BMJ_EBM) August 19, 2022
Reporting guideline for overviews of reviews of healthcare interventions: development of the PRIOR statement.
16 Aug, 2022 | 13:31h | UTC