Evidence-based Medicine
Guidance on Conducting Systematic Reviews and Meta-analyses of Observational Studies of Etiology
27 Feb, 2019 | 13:01h | UTC
Alex Nowbar’s Weekly Research Reviews, 26 February 2019
27 Feb, 2019 | 00:55h | UTCAlex Nowbar’s weekly research reviews, 26 February 2019 – The BMJ Opinion (free)
Study: The Effect of Publishing Peer Review Reports on Referee Behavior in Five Scholarly Journals
25 Feb, 2019 | 00:54h | UTCCommentary: Rare trial of open peer review allays common concerns – Nature (free)
Ann Robinson’s research reviews – 19 February 2019
20 Feb, 2019 | 03:06h | UTCAnn Robinson’s research reviews, 19 February 2019 – The BMJ Opinion (free)
WHO Guidelines for Peri-Operative Hyperoxia Questioned
18 Feb, 2019 | 22:15h | UTCCommentary: Anaesthetists say patients at risk after flawed oxygen guidelines – The Guardian (free)
Zackary Berger’s weekly research reviews – 13 February 2019
14 Feb, 2019 | 01:30h | UTCZackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)
Perspective: “February 7th 2019 marked an auspicious day in the history of the NEJM and its relationship with the pharmaceutical industry.”
13 Feb, 2019 | 01:57h | UTCThe Case of the Scientific Ruse – EMNerd (free)
Five Warning Signs of Overdiagnosis
11 Feb, 2019 | 00:05h | UTCFive warning signs of overdiagnosis – The Conversation (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)
Systematic Reviews May Not Address Adverse Side Effects
10 Feb, 2019 | 15:10h | UTCCommentary: Systematic Reviews May Not Address Adverse Side Effects – MedicalResearch.com (free)
Number Needed to Treat (NNT): Conveying the Likelihood of a Therapeutic Effect
7 Feb, 2019 | 23:03h | UTCGuide to Statistics and Methods: Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect – JAMA (free for a limited period)
Related: Number needed to treat (NNT) in clinical literature: an appraisal – BMC Medicine (free) AND The Numbers Needed to Treat and Harm (NNT, NNH) Statistics: What They Tell Us and What They Do Not – The Journal of Clinical Psychiatry (free)
See also: The NNT Website (resource on the subject with tutorials and practical examples)
No Free Lunch — What Price Plan S for Scientific Publishing?
7 Feb, 2019 | 15:00h | UTCNo Free Lunch — What Price Plan S for Scientific Publishing? – New England Journal of Medicine (free)
Related: Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (commentaries on the subject)
Alex Nowbar’s research reviews – 5 February 2019
7 Feb, 2019 | 01:04h | UTCAlex Nowbar’s research reviews, 5 February 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Study: Undisclosed Financial Ties Between Guideline Writers and Pharmaceutical Companies
7 Feb, 2019 | 00:41h | UTCCommentaries: Undisclosed financial relationships revealed between doctors and drug companies – The Guardian (free) AND 24% of clinical guideline authors may have undisclosed ties to drug industry – Cardiovascular Business (free) AND Influential doctors aren’t disclosing their drug company ties – Croakey (free)
Related: Study: Financial Conflicts of Interest Among Authors of Clinical Guidelines (link to abstract and commentaries) AND Authors of premier medical textbook didn’t disclose $11 million in industry payments (free commentary) AND Study: Financial Conflicts of Interest Among Authors of Urology Guidelines (link to abstract) AND Perspective: Hidden Conflicts? (free) AND Study: Association of Compensation to Physicians From Industry and Self-declared Conflict of Interest (link to abstract and commentaries) AND Study: Financial Conflicts of Interest Among Oncologist Authors of Reports of Clinical Drug Trials (link to abstract and commentaries) AND “What These Medical Journals Don’t Reveal: Top Doctors’ Ties to Industry” (free commentary) AND Study: Assessment of Pharmaceutical Company and Device Manufacturer Payments to Gastroenterologists and Their Participation in Clinical Practice Guideline Panels (free)
Maximizing the Impact of Patient Reported Outcome Assessment for Patients and Society
4 Feb, 2019 | 22:24h | UTCMaximising the impact of patient reported outcome assessment for patients and society – The BMJ (free for a limited period)
Key Concepts for Assessing Claims About Treatment Effects and Making Well-informed Treatment Choices
4 Feb, 2019 | 22:21h | UTC
When Continuous Outcomes are Measured Using Different Scales: Guide for Meta-analysis and Interpretation
3 Feb, 2019 | 16:49h | UTCWhen continuous outcomes are measured using different scales: guide for meta-analysis and interpretation – The BMJ (free for a limited period)
A Guide to Systematic Review and Meta-analysis of Prognostic Factor Studies
3 Feb, 2019 | 11:53h | UTCResearch Methods & Reporting: A guide to systematic review and meta-analysis of prognostic factor studies – The BMJ (free for a limited period)
Ann Robinson’s Research Reviews, 29 January 2019
30 Jan, 2019 | 01:05h | UTCAnn Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
Guide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies
29 Jan, 2019 | 21:46h | UTCGuide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies – JAMA (free for a limited period)
A Guide to Reproducibility in Preclinical Research
29 Jan, 2019 | 21:45h | UTCA Guide to Reproducibility in Preclinical Research – Academic Medicine (free)
Viewpoint: Modernizing Clinical Trials for Patients with Cancer
28 Jan, 2019 | 23:35h | UTCModernizing Clinical Trials for Patients With Cancer – JAMA Oncology (free for a limited period)
Dear Editor (An Authors’ Wish List to Medical Journal Editors)
27 Jan, 2019 | 20:32h | UTCDear Editor (An Authors’ Wish List to Medical Journal Editors) – Microbiology (free)
Opinion: Diversity in Clinical Trials Defines Good Science and Better Medicine
27 Jan, 2019 | 20:08h | UTCDiversity in clinical trials defines good science and better medicine – STAT (free)
Guide to Statistics and Methods: Mediation Analysis
27 Jan, 2019 | 20:06h | UTCMediation Analysis – JAMA (free for a limited period)
Perspective – Real-World Evidence and Randomized Studies in the Precision Oncology Era: The Right Balance
27 Jan, 2019 | 20:04h | UTC


