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Evidence-based Medicine

Guidance on Conducting Systematic Reviews and Meta-analyses of Observational Studies of Etiology

27 Feb, 2019 | 13:01h | UTC

COSMOS-E: Guidance on conducting systematic reviews and meta-analyses of observational studies of etiology – PLOS Medicine (free)

 


Alex Nowbar’s Weekly Research Reviews, 26 February 2019

27 Feb, 2019 | 00:55h | UTC

Alex Nowbar’s weekly research reviews, 26 February 2019 – The BMJ Opinion (free)

 


Study: The Effect of Publishing Peer Review Reports on Referee Behavior in Five Scholarly Journals

25 Feb, 2019 | 00:54h | UTC

The effect of publishing peer review reports on referee behavior in five scholarly journals – Nature Communications (free)

Commentary: Rare trial of open peer review allays common concerns – Nature (free)

 


Ann Robinson’s research reviews – 19 February 2019

20 Feb, 2019 | 03:06h | UTC

Ann Robinson’s research reviews, 19 February 2019 – The BMJ Opinion (free)

 


WHO Guidelines for Peri-Operative Hyperoxia Questioned

18 Feb, 2019 | 22:15h | UTC

Evidence for compromised data integrity in studies of liberal peri‐operative inspired oxygen – Anaesthesia (free)

Commentary: Anaesthetists say patients at risk after flawed oxygen guidelines – The Guardian (free)

 


Zackary Berger’s weekly research reviews – 13 February 2019

14 Feb, 2019 | 01:30h | UTC

Zackary Berger’s weekly research reviews, 13 February 2019 – The BMJ Opinion (free)

 


Perspective: “February 7th 2019 marked an auspicious day in the history of the NEJM and its relationship with the pharmaceutical industry.”

13 Feb, 2019 | 01:57h | UTC

The Case of the Scientific Ruse – EMNerd (free)

 


Five Warning Signs of Overdiagnosis

11 Feb, 2019 | 00:05h | UTC

Five warning signs of overdiagnosis – The Conversation (free)

Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)

 


Systematic Reviews May Not Address Adverse Side Effects

10 Feb, 2019 | 15:10h | UTC

More than one-third of systematic reviews did not fully report the adverse events outcome – Journal of Clinical Epidemiology (free)

Commentary: Systematic Reviews May Not Address Adverse Side Effects – MedicalResearch.com (free)

 


Number Needed to Treat (NNT): Conveying the Likelihood of a Therapeutic Effect

7 Feb, 2019 | 23:03h | UTC

Guide to Statistics and Methods: Number Needed to Treat: Conveying the Likelihood of a Therapeutic Effect – JAMA (free for a limited period)

Related: Number needed to treat (NNT) in clinical literature: an appraisal – BMC Medicine (free) AND The Numbers Needed to Treat and Harm (NNT, NNH) Statistics: What They Tell Us and What They Do Not – The Journal of Clinical Psychiatry (free)

See also: The NNT Website (resource on the subject with tutorials and practical examples)

 


No Free Lunch — What Price Plan S for Scientific Publishing?

7 Feb, 2019 | 15:00h | UTC

No Free Lunch — What Price Plan S for Scientific Publishing? – New England Journal of Medicine (free)

Related: Open Access 2018: A Year of Funders and Universities Drawing Lines in the Sand (commentaries on the subject)

 


Alex Nowbar’s research reviews – 5 February 2019

7 Feb, 2019 | 01:04h | UTC

Alex Nowbar’s research reviews, 5 February 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


Study: Undisclosed Financial Ties Between Guideline Writers and Pharmaceutical Companies

7 Feb, 2019 | 00:41h | UTC

Undisclosed financial ties between guideline writers and pharmaceutical companies: a cross-sectional study across 10 disease categories – BMJ Open (free)

Commentaries: Undisclosed financial relationships revealed between doctors and drug companies – The Guardian (free) AND 24% of clinical guideline authors may have undisclosed ties to drug industry – Cardiovascular Business (free) AND Influential doctors aren’t disclosing their drug company ties – Croakey (free)

Related: Study: Financial Conflicts of Interest Among Authors of Clinical Guidelines (link to abstract and commentaries) AND Authors of premier medical textbook didn’t disclose $11 million in industry payments (free commentary) AND Study: Financial Conflicts of Interest Among Authors of Urology Guidelines (link to abstract) AND Perspective: Hidden Conflicts? (free) AND Study: Association of Compensation to Physicians From Industry and Self-declared Conflict of Interest (link to abstract and commentaries) AND Study: Financial Conflicts of Interest Among Oncologist Authors of Reports of Clinical Drug Trials (link to abstract and commentaries) AND “What These Medical Journals Don’t Reveal: Top Doctors’ Ties to Industry” (free commentary) AND Study: Assessment of Pharmaceutical Company and Device Manufacturer Payments to Gastroenterologists and Their Participation in Clinical Practice Guideline Panels (free)

 


Maximizing the Impact of Patient Reported Outcome Assessment for Patients and Society

4 Feb, 2019 | 22:24h | UTC

Maximising the impact of patient reported outcome assessment for patients and society – The BMJ (free for a limited period)

 


Key Concepts for Assessing Claims About Treatment Effects and Making Well-informed Treatment Choices

4 Feb, 2019 | 22:21h | UTC

Key Concepts for assessing claims about treatment effects and making well-informed treatment choices – F1000Research (free)

 


When Continuous Outcomes are Measured Using Different Scales: Guide for Meta-analysis and Interpretation

3 Feb, 2019 | 16:49h | UTC

When continuous outcomes are measured using different scales: guide for meta-analysis and interpretation – The BMJ (free for a limited period)

 


A Guide to Systematic Review and Meta-analysis of Prognostic Factor Studies

3 Feb, 2019 | 11:53h | UTC

Research Methods & Reporting: A guide to systematic review and meta-analysis of prognostic factor studies – The BMJ (free for a limited period)

 


Ann Robinson’s Research Reviews, 29 January 2019

30 Jan, 2019 | 01:05h | UTC

Ann Robinson’s research reviews, 29 January 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Guide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies

29 Jan, 2019 | 21:46h | UTC

Guide to Statistics and Methods: Using the E-Value to Assess the Potential Effect of Unmeasured Confounding in Observational Studies – JAMA (free for a limited period)

 


A Guide to Reproducibility in Preclinical Research

29 Jan, 2019 | 21:45h | UTC

A Guide to Reproducibility in Preclinical Research – Academic Medicine (free)

 


Viewpoint: Modernizing Clinical Trials for Patients with Cancer

28 Jan, 2019 | 23:35h | UTC

Modernizing Clinical Trials for Patients With Cancer – JAMA Oncology (free for a limited period)

 


Dear Editor (An Authors’ Wish List to Medical Journal Editors)

27 Jan, 2019 | 20:32h | UTC

Dear Editor (An Authors’ Wish List to Medical Journal Editors) – Microbiology (free)

 


Opinion: Diversity in Clinical Trials Defines Good Science and Better Medicine

27 Jan, 2019 | 20:08h | UTC

Diversity in clinical trials defines good science and better medicine – STAT (free)

 


Guide to Statistics and Methods: Mediation Analysis

27 Jan, 2019 | 20:06h | UTC

Mediation Analysis – JAMA (free for a limited period)

 


Perspective – Real-World Evidence and Randomized Studies in the Precision Oncology Era: The Right Balance

27 Jan, 2019 | 20:04h | UTC

Real-World Evidence and Randomized Studies in the Precision Oncology Era: The Right Balance – JCO Precision Oncology (free)

 


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