Endocrinology (all articles)
Review: Perioperative Management of the Diabetic Patient Referred to Cardiac Surgery
17 Mar, 2019 | 18:16h | UTC
Evidence Evolving on Aspirin as Prevention
13 Mar, 2019 | 06:04h | UTCEvidence evolving on aspirin as prevention – ACP Internist (free)
Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)
“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”
Randomized Trial: Thyroidectomy vs. Medical Management for Euthyroid Patients with Hashimoto Disease and Persisting Symptoms
12 Mar, 2019 | 17:28h | UTCThyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Thyroidectomy Seems to Improve Quality of Life in Hashimoto Disease – NEJM Journal Watch (free) AND Thyroidectomy more effective than medication for Hashimoto disease with persisting symptoms – 2 Minute Medicine (free)
“Results are applicable only to a subgroup of patients with Hashimoto disease, and follow-up was limited to 18 months.”
Viewpoint: Reexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults
12 Mar, 2019 | 02:46h | UTCReexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults – JAMA (free for a limited period)
“This Viewpoint discusses the 2018 ACC/AHA cholesterol management guideline recommendation to consider statin treatment in adults aged >75 years with LDL levels 70-189 mg/dL, arguing that trial evidence does not support it…”
Meta-Analysis: Carbohydrate Restriction for Glycemic Control in Type 2 Diabetes
11 Mar, 2019 | 12:09h | UTC
Review: Diagnosing and Managing Diabetic Somatic and Autonomic Neuropathy
11 Mar, 2019 | 03:39h | UTC
Observational Study Suggests Postmenopausal Hormone Therapy is Linked to a Small Risk of Alzheimer’s Disease
11 Mar, 2019 | 03:33h | UTCEditorial: Menopausal hormone therapy and cognition (free)
Commentaries: Systemic Hormone Therapy Tied to Small Increase in Alzheimer’s Risk – NEJM Journal Watch (free) AND ‘Small’ increase in risk of Alzheimer’s disease with HRT use, study suggests – NHS Choices (free)
“The findings of this case-control study, with the modest effect sizes and substantial potential for bias, will not change how I counsel patients regarding benefits and risks of HT.” (from Journal Watch)
“Evidence is reassuring for women needing a few years’ treatment for menopausal symptoms” (from Editorial)
Opinion: The War on ‘Prediabetes’ Could be a Boon for Pharma—But is it Good Medicine?
8 Mar, 2019 | 06:16h | UTCThe war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science (free)
Related Commentary on Twitter
The case that pre-#diabetes is a questionable diagnosis, no less its treatment https://t.co/aowaKzMa3b
by @cpiller @sciencemagazine pic.twitter.com/ZlzE3dbE0a— Eric Topol (@EricTopol) March 7, 2019
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
7 Mar, 2019 | 02:37h | UTCCommentaries: Statins associated with 38 per cent increased risk of type 2 diabetes – Diabetes.co.uk (free) AND Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes – News Medical (free)
Review: Glucose Control in the ICU
6 Mar, 2019 | 01:27h | UTCGlucose control in the ICU – Current Opinion in Anesthesiology (free)
Source: Critical Care Reviews Newsletter
Meta-Analysis: High-intensity Interval Training (HIIT) vs. Moderate-intensity Continuous Training for Weight Loss
4 Mar, 2019 | 00:13h | UTCIs interval training the magic bullet for fat loss? A systematic review and meta-analysis comparing moderate-intensity continuous training with high-intensity interval training (HIIT) – British Journal of Sports Medicine (link to abstract – $ for full-text)
Commentaries: The Best Type of Exercise to Burn Fat – The New York Times (10 articles per month are free) AND Short bursts of intense exercise ‘better for weight loss’ – BBC (free) AND Short intense exercise regimes may aid weight loss – OnMedica (free)
Related Commentary on Twitter
Interval training may shed more pounds than a continuous moderate intensity workout, suggests a pooled analysis of the available evidence, published online in @BJSM_BMJ https://t.co/Oy0Z5NlRqr pic.twitter.com/Fqkgeu3FLk
— BMJ Group (@bmj_company) February 15, 2019
Review: Immune Checkpoint Inhibitors-induced Endocrinopathies in Cancer Patients
25 Feb, 2019 | 00:55h | UTCRelated Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Study: Diagnostic Performance of Practice Guidelines for Thyroid Nodules
25 Feb, 2019 | 00:40h | UTCRelated Guidelines: 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer (free) AND Ultrasonography Diagnosis and Imaging-Based Management of Thyroid Nodules: Revised Korean Society of Thyroid Radiology Consensus Statement and Recommendations (free) AND ACR Thyroid Imaging, Reporting and Data System (TI-RADS): White Paper of the ACR TI-RADS Committee (free)
Study: Preventing Misdiagnosis of Diabetes in the Elderly Through Age-dependent HbA1c Reference Intervals
22 Feb, 2019 | 01:36h | UTCCommentary: Should HbA1c cutoffs for DM diagnosis be higher in older adults? – Univadis (free registration required)
Related Commentary on Twitter
HbA1c increases with age in people without diabetes–should there be different cut-points for diagnosis of diabetes in elderly?https://t.co/5FvRXrMBvS@ABCDiab @IntDiabetesFed @DiabetesUK @ADA_DiabetesPro @DiabetesCanada @AmDiabetesAssn @AmarPut @parthaskar @drpatrickholmes
— Prof Kamlesh Khunti (@kamleshkhunti) February 16, 2019
Subclinical Hypothyroidism: When to Treat
18 Feb, 2019 | 21:49h | UTCSubclinical hypothyroidism: When to treat – Cleveland Clinic Journal of Medicine (free)
Related: Thyroid Hormone Treatment Does Not Help Adults with Mildly Abnormal Thyroid Tests (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)
Pediatric Obesity Algorithm: A Practical Approach to Obesity Diagnosis and Management
18 Feb, 2019 | 21:44h | UTC
Diabetes Poland 2019 Guidelines for the Management of Diabetes
12 Feb, 2019 | 15:32h | UTCRelated Guidelines: ADA 2019 Standards of Medical Care in Diabetes (free supplement) AND AACE/ACE Comprehensive Type 2 Diabetes Management Algorithm 2019 – Endocrine Practice (Free PDF and Slide Presentations) AND Diabetes Canada 2018 clinical practice guidelines for the prevention and management of diabetes in Canada (free)
Review: Identifying and Managing Younger Women at High Risk of Cardiovascular Disease
12 Feb, 2019 | 00:21h | UTCIdentifying and managing younger women at high risk of cardiovascular disease – Canadian Medical Association Journal (free for 7 days)
Related Reviews: Knowledge, Attitudes, and Beliefs Regarding Cardiovascular Disease in Women: The Women’s Heart Alliance – Journal of the American College of Cardiology (free)
Related guidelines: Preventing and Experiencing Ischemic Heart Disease as a Woman: State of the Science: A Scientific Statement From the American Heart Association (free) AND Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association (free) AND AHA/ACOG: Reduction of Cardiovascular Disease in Women Through Collaboration with Obstetricians and Gynecologists (free)
Study: Only a Minority of Adults and Youth with T1D Achieve ADA goals for HbA1c
11 Feb, 2019 | 21:03h | UTCCommentary: Minority of patients with type 1 diabetes achieve ADA goals for glycemic control, study finds – ACP Diabetes (free)
Randomized Trial: Intense IV Blood Sugar Control Doesn’t Improve Stroke Outcomes
11 Feb, 2019 | 00:15h | UTCCommentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)
Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)
“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)
Systematic Review Supports Lengthening of the Screening Interval of Patients with Type 2 Diabetes Without Retinopathy at Last Screening Session
10 Feb, 2019 | 23:58h | UTCCommentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)
Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)
“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”
Cohort Study: Effect of Gastric Bypass Surgery on Diabetes Remission and Complications
10 Feb, 2019 | 15:44h | UTCEffect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: a Danish population-based matched cohort study – Diabetologia (free for a limited period)
Commentary: Gastric Bypass Surgery Linked to Diabetes Remission – MedicalResearch.com (free)
Study: Association of Thyrotropin Suppression with Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer
10 Feb, 2019 | 13:59h | UTCCommentary: Study Evaluates Thyroid Hormone Suppression For High Risk Thyroid Cancer – MedicalResearch.com (free)
“This study provides the justification for a randomized trial.”
Randomized Trial: Alirocumab for Secondary Prevention of Cardiovascular Disease
10 Feb, 2019 | 13:57h | UTCCommentary: Alirocumab reduces risk of initial and repeat CV events after ACS – Cardiovascular Business (free)
Original Research: Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome (link to abstract and commentaries)
JAMA Clinical Guidelines Synopsis: Management of Blood Cholesterol
4 Feb, 2019 | 23:53h | UTCGuideline Synopsis: Management of Blood Cholesterol – JAMA (free)
Editorial: A New Personalized, Patient-Centric, and Cost-Conscious Guideline for Contemporary Cholesterol Management (free)
Original Guideline: New AHA/ACC Guideline on the Management of Blood Cholesterol (free guideline and resources)