Editor's Choice
WHO reveals shocking extent of exploitative formula milk marketing.
29 Apr, 2022 | 10:58h | UTCNews Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 WHO report reveals shocking extent of exploitative formula milk marketing
The formula milk industry, valued at US$55 billion, is paying social media platforms & influencers to gain direct access to pregnant women & mothers.#EndExploitativeMarketing
👉https://t.co/0dciNxB0fQ pic.twitter.com/hhAnyp0ueH— World Health Organization (WHO) (@WHO) April 29, 2022
Review: Understanding vaccine safety and the roles of the FDA and the CDC.
29 Apr, 2022 | 11:13h | UTCUnderstanding Vaccine Safety and the Roles of the FDA and the CDC – New England Journal of Medicine
Commentary on Twitter
Development and public acceptance of vaccines are crucial for disease control. Cody Meissner, M.D., reviews the process of evaluating vaccine safety and efficacy and factors that advisory bodies consider in making recommendations. https://t.co/ITqpGthoac pic.twitter.com/HTkyAaWvDO
— NEJM (@NEJM) April 28, 2022
RCT: BCG vaccine is not effective in reducing healthcare worker absenteeism in COVID-19 pandemic.
29 Apr, 2022 | 11:05h | UTC
Commentary on Twitter
BCG-CORONA RCT💥 @CMIJournal @MarcBonten
BCG-vaccination of health care worker exposed to #COVID19 patients did NOT reduce unplanned absenteeism nor documented COVID-19 #IDTwitter #MedEd #TwitteRx #MedTwitter https://t.co/yqnpmuy5Y8— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 28, 2022
Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.
29 Apr, 2022 | 11:07h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
The Lancet Series: Optimizing child and adolescent health and development.
29 Apr, 2022 | 10:55h | UTCHomepage: Optimising Child and Adolescent Health and Development – The Lancet (free registration required for all articles)
Health and development from preconception to 20 years of age and human capital
Optimising child and adolescent health and development in the post-pandemic world
Opportunities in crisis for optimising child health and development
M-A: Household secondary attack rates of SARS-CoV-2 by variant and vaccination status.
29 Apr, 2022 | 10:57h | UTC
Commentary on Twitter
This systematic review & meta-analysis found household #SARSCoV2 secondary attack rates increased over time and were higher for variants than prior reported estimates. Vaccination was associated with reduced transmission (more for Alpha vs Delta & Omicron) https://t.co/6vwW0u3vY7
— JAMA Network Open (@JAMANetworkOpen) April 28, 2022
Analysis | Presenting complaint: use of language that disempowers patients.
28 Apr, 2022 | 11:02h | UTCPresenting complaint: use of language that disempowers patients – The BMJ
News Release: Language that belittles or blames patients is overdue for change – British Medical Journal
Covid-19: What is the evidence for the antiviral Paxlovid?
28 Apr, 2022 | 10:58h | UTCCovid-19: What is the evidence for the antiviral Paxlovid? – The BMJ
Related:
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
A living WHO guideline on drugs for covid-19 – The BMJ
Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis.
28 Apr, 2022 | 10:56h | UTC
Commentary on Twitter
https://twitter.com/bmj_latest/status/1519430941759918080
Experts fear U.S. may default to annual Covid boosters without sufficient data.
28 Apr, 2022 | 10:51h | UTCExperts fear U.S. may default to annual Covid boosters without sufficient data – STAT
Commentary on Twitter
Vaccine experts are concerned the U.S. may be sleepwalking into a policy of recommending annual Covid-19 vaccine boosters — without having generated the evidence to show they are actually needed. https://t.co/3TiNZvP0HY
— STAT (@statnews) April 26, 2022
Public health impact of covid-19 vaccines in the US: observational study.
28 Apr, 2022 | 10:54h | UTCPublic health impact of covid-19 vaccines in the US: observational study – The BMJ
Editorial: The benefits of large scale covid-19 vaccination – The BMJ
Commentary on Twitter (thread – click for more)
Paper and accompanying editorial https://t.co/uwqY0PqYsE
"Many more lives could have been saved……
this new study is another confidence booster for covid-19 vaccines." pic.twitter.com/o4FygrAX8T— Eric Topol (@EricTopol) April 27, 2022
Study Commentary | Palliative and end of life care should not wait for a prediction of death.
28 Apr, 2022 | 10:44h | UTCOriginal Study: Timely community palliative and end-of-life care: a realist synthesis – BMJ Supportive & Palliative Care
USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.
27 Apr, 2022 | 08:16h | UTCAuthor Interview: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease – JAMA
Modeling Study: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force – JAMA
Patient Page: Use of Aspirin to Prevent Cardiovascular Disease – JAMA
Editorials:
Aspirin for Primary Prevention—Time to Rethink Our Approach – JAMA Network Open
USPSTF Report on Aspirin for Primary Prevention – JAMA Cardiology
Commentaries:
USPSTF Report on Aspirin for Primary Prevention – American College of Cardiology
USPSTF Finalizes Tougher Stance on Aspirin in Primary Prevention – TCTMD
U.S. Task Force Rejects Daily Aspirin for Heart Health in People Over 60 – HealthDay
NICE Guideline: Epilepsies in children, young people and adults.
27 Apr, 2022 | 08:14h | UTCEpilepsies in children, young people and adults – National Institute for Health and Care Excellence
Clinical Review: Diagnosis and management of covid-19 in pregnancy.
27 Apr, 2022 | 08:13h | UTCDiagnosis and management of covid-19 in pregnancy – The BMJ
Observational study suggests calcium supplementation may increase adverse outcomes in patients with aortic stenosis.
27 Apr, 2022 | 08:12h | UTCSupplemental calcium and vitamin D and long-term mortality in aortic stenosis – Heart
News Release: Calcium supps linked to earlier death in older people with heart valve disease – BMJ
RCT: No influence of supplemental Vitamin K2 and D in the progression of aortic valve calcification.
27 Apr, 2022 | 08:10h | UTCCommentary: AHA News: Despite Hopes, Vitamin K2 Supplements Fail to Slow Calcium Buildup in Heart Valve – HealthDay
Review: The evolving clinical practice of chronic cough.
27 Apr, 2022 | 08:06h | UTCThe Evolving Clinical Practice of Chronic Cough – Mayo Clinic Proceedings
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
Cohort Study: Incidence of Guillain-Barré syndrome after Covid-19 vaccination in the vaccine safety datalink.
27 Apr, 2022 | 08:03h | UTC
Commentary on Twitter
This cohort study of #COVID19 vaccine safety surveillance in the US Vaccine Safety Datalink found a small elevated risk of Guillain-Barré syndrome after Janssen/J&J vaccine but not after mRNA COVID-19 vaccines. @KPDOR https://t.co/TTya5BDqeV
— JAMA Network Open (@JAMANetworkOpen) April 26, 2022
Covid-19: Only a quarter of patients admitted to hospital feel fully recovered after a year, study finds.
26 Apr, 2022 | 08:45h | UTCInvited Commentary: Long COVID: systemic inflammation and obesity as therapeutic targets – The Lancet Respiratory Medicine
Commentary on Twitter (thread – click for more)
PHOSP-COVID study:
– 232 (29%) of 804 pts fully recovered at 1y
– Female sex, obesity, & IMV = less likely to feel fully recovered
– inflamm mediators📈in those w/ most severe physical, mental health, & cognitive impairmentsRead it here: https://t.co/rVZuVDo4xl
— The Lancet Respiratory Medicine (@LancetRespirMed) April 25, 2022
Persistent COVID-19 symptoms in a community study of 606,434 people in England.
26 Apr, 2022 | 08:48h | UTC
Commentary on Twitter
Thirty-eight percent of participants from a community-based study of symptoms following COVID-19 reported persistent symptoms that lasted 12 weeks or more, according to an article published in @NatureComms. https://t.co/sAEutdOkSS pic.twitter.com/oCyyXGIRbk
— Nature Portfolio (@NaturePortfolio) April 20, 2022
Cohort Study: Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations.
26 Apr, 2022 | 08:21h | UTCNews Release: Study suggests association between severe COVID-19 and long-term mental health outcomes 16 months after an illness – Lancet
Commentary: Lasting depression and anxiety can follow severe case of Covid – NBC News
Commentary on Twitter (thread – click for more)
https://twitter.com/COVIDMENT/status/1513511696979329024
Practice Pointer: Making decisions about radiological imaging in pregnancy.
26 Apr, 2022 | 08:44h | UTCMaking decisions about radiological imaging in pregnancy – The BMJ
Yes, relapses after Paxlovid happen — now what?
26 Apr, 2022 | 08:18h | UTCYes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
Commentary on Twitter
Some additional thoughts about relapsing Covid19 after treatment with Paxlovid.
Bottom line — *lots* of unknowns, starting w/ how often it happens.
Looking forward to @pfizer sharing further data on the relapsing cases from their EPIC-HR study. https://t.co/1MMhqn4elw
— Paul Sax (@PaulSaxMD) April 25, 2022