Editor's Choice
Opinion: COVID-19 in 2022—The beginning of the end or the end of the beginning?
31 May, 2022 | 11:32h | UTCCOVID-19 in 2022—The Beginning of the End or the End of the Beginning? – JAMA
Most doctors still believe in prescribing unnecessary antibiotics to treat asymptomatic bacteriuria, study suggests.
31 May, 2022 | 11:31h | UTC
Commentary on Twitter
🆕💥💥@jamanetworkopen @dr_dmorgan et Al
In this survey study of 551 primary care clinicians, 392 (71%) reported that they would prescribe antibiotics for asymptomatic bacteriuria, shocking? #IDTwitter @BradSpellberg @DrToddLee @InfectiousDz @bwtrautnerhttps://t.co/tekcQVsfqk pic.twitter.com/1fRakHgjU7— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 27, 2022
[News release – not published yet] RCT: Doxycycline after unprotected sex significantly reduced STIs – study of men who have sex with men and transgender women stopped early for effectiveness.
30 May, 2022 | 11:57h | UTC
Evidence-based recommendations on texture modified foods and thickened liquids for adults with oropharyngeal dysphagia – “There is no convincing evidence that thickened liquid or texture modified diet prevents death or pneumonia nor improves the quality of life, nutritional status, or oral intake in individuals with OD”.
30 May, 2022 | 11:54h | UTC
Guidelines for clothing in the operating theatre.
30 May, 2022 | 11:52h | UTCGuidelines for clothing in the operating theatre, 2021 – Anaesthesia Critical Care & Pain Medicine
Consensus: nephrotoxic potential of 167 drugs in adult critically ill patients.
30 May, 2022 | 11:50h | UTCConsensus Obtained for the Nephrotoxic Potential of 167 Drugs in Adult Critically Ill Patients Using a Modified Delphi Method – Drug Safety (if the link is paywalled, try this one)
WHO launches new guide on integrating eye care in health systems.
30 May, 2022 | 11:48h | UTCNews Release: WHO launches new guide on integrating eye care in health systems – World Health Organization
WHO Guidance: Eye care in health systems: guide for action – World Health Organization
Editorial: Chance encounters, overdiagnosis, and overtreatment in orthopedic surgery.
30 May, 2022 | 11:43h | UTC
Commentary on Twitter
"Shoulder, back, and knee pain are part of life and part of aging; when they overlap with age-related MRI findings, which probably do not have anything to do with the presenting complaint, we get overdiagnosis."https://t.co/XLG5RQ7vfo
— Derek Griffin (@DerekGriffin86) May 27, 2022
Analysis/Opinion: The unintended consequences of COVID-19 vaccine policy: “why mandates, passports and restrictions may cause more harm than good”.
30 May, 2022 | 11:46h | UTC
Commentary on Twitter (thread – click for more)
📢 Our paper on COVID-19 vaccine policy has been published💉🦠
We discuss 12 unintended consequences of mandates and passports across society
& argue that pandemic vaccine policies have caused more social harm than good
Read the paper: https://t.co/TeyTki0nWI pic.twitter.com/BRJQRURbUc
— Kevin Bardosh (@KevinBardosh) May 26, 2022
Monkeypox outbreaks: 4 key questions researchers have.
30 May, 2022 | 11:36h | UTCMonkeypox outbreaks: 4 key questions researchers have – Nature
Related:
Study reports first use of antivirals in monkeypox patients – Lancet
Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization
Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization
A Novel International Monkeypox Outbreak – Annals of Internal Medicine
EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT
Monkeypox cases increase across Europe, North America – CIDRAP
Multi-country monkeypox outbreak in non-endemic countries – World Health Organization
Monkeypox goes global: why scientists are on alert – Nature
Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT
Monkeypox: Time to worry or one to ignore? – BBC
UK, Spain, Portugal report more monkeypox cases – CIDRAP
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
M-A: Effects of intermittent fasting compared to a non-intervention diet and caloric restriction.
30 May, 2022 | 11:45h | UTCRelated:
Time-Restricted Eating: Integrating The What With The When – Advances in Nutrition
Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine (link to abstract – $ for full-text)
Investigating acute hepatitis of unknown origin in children.
30 May, 2022 | 11:39h | UTCInvestigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
Related:
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
Unexplained, severe acute hepatitis has been increasingly reported in children. Adenovirus has been detected in some (but not all) cases & is being investigated as 1 of many potential causes. @andreaprinzi discusses the ongoing epidemiologic investigation: https://t.co/P6EPdT8sOA
— ASM (@ASMicrobiology) May 27, 2022
M-A: Gestational diabetes mellitus and adverse pregnancy outcomes.
27 May, 2022 | 12:25h | UTC
Commentary on Twitter
NEW research finds gestational diabetes is associated with increased odds of a range of complications for both mother and baby, including caesarean delivery, severe breathing problems, and excessive birth weight https://t.co/oyzkFxMslc
— The BMJ (@bmj_latest) May 26, 2022
RCT: Vitamin D does not prevent type 2 diabetes in high risk adults, trial finds.
27 May, 2022 | 12:24h | UTCNews Release: Vitamin D does not prevent type 2 diabetes in high risk adults, trial finds – BMJ
Original Study: Effect of active vitamin D treatment on development of type 2 diabetes: DPVD randomised controlled trial in Japanese population – The BMJ
Editorial: Vitamin D and risk of type 2 diabetes – The BMJ
Dairy consumption and risks of total and site-specific cancers in Chinese adults: an 11-year prospective study of 0.5 million people.
27 May, 2022 | 12:20h | UTCNews Release: Dairy products linked to increased risk of cancer – University of Oxford
Cohort Study: Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes.
27 May, 2022 | 12:22h | UTCNews Release: Painkiller advice for pregnant women should always be followed, as use is linked to newborn problems – University of Aberdeen
Related:
Paracetamol use during pregnancy — a call for precautionary action – Nature Reviews Endocrinology
Editorial: Caution needed: paracetamol use in pregnancy – Nature Reviews Endocrinology
Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening.
27 May, 2022 | 12:17h | UTC
Commentary on Twitter
RV failure in moderate-to-severe #COVID19 #ARDS
➡️strong predictor of mortality
➡️significant worsening of PaO2/FiO2, PaCO2 & ventilatory ratio (⬆️ pulm vasoconstriction) & ⬆️ driving P could contribute#POCUS mandatory especially if resp deterioration.
📎 https://t.co/OE56BuxeWz pic.twitter.com/dNIeo1yHcP— Intensive Care Medicine (@yourICM) May 16, 2022
Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019.
27 May, 2022 | 12:15h | UTCCommentaries:
Need for improved global measurement of early childhood respiratory syncytial virus disease – The Lancet (free registration required)
RSV kills 100,000 kids under age 5 a year worldwide – CHEST Physician
Pivot into COVID-19 research eases as publishing surge starts to level off – Researchers who jumped into the field from distant disciplines published lower impact work, study finds.
27 May, 2022 | 12:18h | UTCPivot into COVID-19 research eases as publishing surge starts to level off – Science
Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds.
27 May, 2022 | 12:04h | UTCCommentary: Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds – The BMJ
A comprehensive evaluation of COVID-19 policies and outcomes in 50 countries and territories.
27 May, 2022 | 12:11h | UTC
Top studies of 2021 relevant to primary care.
26 May, 2022 | 10:55h | UTCTop studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician
Study reports first use of antivirals in monkeypox patients.
26 May, 2022 | 11:27h | UTCNews Release: Study reports first use of antivirals in monkeypox patients – Lancet
Original Study: Clinical features and management of human monkeypox: a retrospective observational study in the UK – The Lancet Infectious Diseases
Commentary: Antiviral drug may limit monkeypox symptom duration, infectiousness – CIDRAP
Commentary from one of the author on Twitter (thread – click for more)
https://twitter.com/OutbreakJake/status/1529229623908761601
Cohort Study: Protection and waning of natural and hybrid immunity to SARS-CoV-2.
26 May, 2022 | 11:07h | UTCProtection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Editorial: Audio Interview: Waning Immunity against Covid-19
Commentary on Twitter
Protection against SARS-CoV-2 waned over time in both vaccinated and previously infected persons; an additional vaccine dose restored protection, find investigators from Israel. https://t.co/617uBmWu8l pic.twitter.com/yiDnBbCuQ5
— NEJM (@NEJM) May 25, 2022
Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows.
26 May, 2022 | 11:25h | UTCCommentary: Long COVID risk falls only slightly after vaccination, huge study shows – Nature
Original Study: Long COVID after breakthrough SARS-CoV-2 infection – Nature Medicine
Commentary from the author on Twitter (thread – click for more)
The latest from our team in @NatureMedicine
Does vaccination protect from #LongCovid?
Vaccines modestly reduce but do not eliminate risk of Long Covid @VAResearch @vahsrd @WUSTLmed @WUSTLnews @VREFSTL@Biostayan @BCBowe https://t.co/UEexmL8svS
A thread 🧵
— Ziyad Al-Aly, MD (@zalaly) May 25, 2022