Editor's Choice
RCT: Marine Omega-3 Fatty acid supplementation does not reduce the incidence of dry eye disease in healthy adults.
10 Jun, 2022 | 12:25h | UTCEfficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial – JAMA Ophthalmology (free for a limited period)
Invited Commentary: Another Disappointment for ω-3 Fatty Acid and Dry Eye Disease – JAMA Ophthalmology (free for a limited period)
Commentary on Twitter
In this randomized clinical trial, daily supplementation with marine omega-3 fatty acids (1 gram) for a median of 5.3 years had no significant effect on the incidence of diagnosed #dryeyedisease (DED) or reported DED symptoms. https://t.co/iTBONh6CZK
— JAMA Ophthalmology (@JAMAOphth) June 9, 2022
Another study suggests the Omicron variant is associated with a reduced risk of Multisystem Inflammatory Syndrome in Children compared to previous SARS-CoV-2 variants.
10 Jun, 2022 | 12:38h | UTCRelated study: Severity and Incidence of Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel – JAMA AND Commentary: Kids’ COVID syndrome—MIS-C—less severe in Omicron – CIDRAP
Commentary on Twitter
Study found that the risk of multisystem inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection during the #Omicron wave substantially lower compared to previous #SARSCoV2 variants. https://t.co/GYrz9XA72Z
— JAMA Pediatrics (@JAMAPediatrics) June 8, 2022
Cohort Study: Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy.
10 Jun, 2022 | 12:14h | UTCCommentaries:
Commentary on Twitter
This cohort study of #SARSCoV2 exposure in utero found preliminary evidence that maternal SARS-CoV-2 may be associated with neurodevelopmental sequelae in some offspring. https://t.co/dYdoJbNOdl
— JAMA Network Open (@JAMANetworkOpen) June 9, 2022
M-A: Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections.
10 Jun, 2022 | 12:00h | UTC
Review: The burden and risks of emerging complications of diabetes mellitus.
10 Jun, 2022 | 12:04h | UTCThe burden and risks of emerging complications of diabetes mellitus – Nature Reviews Endocrinology
Commentary on Twitter
New content online: The burden and risks of emerging complications of diabetes mellitus https://t.co/mWcYa7TsKz
— Nature Reviews Endocrinology (@NatureRevEndo) June 6, 2022
Guidance Statement: Surgical triage and timing for patients with COVID undergoing thoracic surgery.
10 Jun, 2022 | 11:58h | UTC
Review: Pathophysiology and mechanism of long COVID.
10 Jun, 2022 | 11:55h | UTCPathophysiology and mechanism of long COVID: a comprehensive review – Annals of Medicine
[Preprint] Largest study to date on long COVID identifies a broad list of diagnoses.
10 Jun, 2022 | 11:53h | UTCStudy Commentary: Largest study to date on long COVID identifies a broad list of diagnoses – News Medical
Commentary on Twitter
🚨 The arguably largest #LongCovid study to date with millions of participants shows the increased risk of various symptoms after infection and the risk of having to take medications. https://t.co/DSvRcKVKIs pic.twitter.com/uUQxK1VQLv
— Jonas R. Kunst (@kunstjonas.bsky.social) (@KunstJonas) May 23, 2022
NICE Guideline: Gout diagnosis and management.
9 Jun, 2022 | 11:35h | UTCGout: diagnosis and management – National Institute for Health and Care Excellence
Study shows a person’s height impacts their risk of multiple diseases.
9 Jun, 2022 | 11:34h | UTCNews Release: A person’s height impacts their risk of multiple diseases – Public Library of Science
Original Study: A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program – PLOS Genetics
CDC Report: Pediatric melatonin ingestions in the US.
9 Jun, 2022 | 11:32h | UTCPediatric Melatonin Ingestions — United States, 2012–2021 – Morbidity and Mortality Weekly Report
Commentaries:
Thousands of kids are getting sick from downing melatonin pills – NPR
Melatonin poisoning reports are up in kids, study says – Associated Press
Melatonin Overdoses Among Kids Are Up 530%, New Research Finds – TIME
Reports of melatonin poisoning in kids have increased 530% since 2012 – Yahoo News
Commentary on Twitter
New MMWR describes a 530% increase in pediatric melatonin ingestions reported to US poison control over the last decade; the largest increase occurred during the pandemic. https://t.co/SwJqTRG4s9 pic.twitter.com/AUxBrGX0Hj
— MMWR (@CDCMMWR) June 3, 2022
[News release – not published yet] Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn.
9 Jun, 2022 | 11:31h | UTCCommentary: Women in UK ‘seldom’ told drug used in surgery can impede contraception – The Guardian
Review: Deprescribing in palliative cancer care.
9 Jun, 2022 | 11:28h | UTCDeprescribing in Palliative Cancer Care – Life
Screening every five years safe for women who test negative for HPV, study confirms.
9 Jun, 2022 | 11:26h | UTCNews Release: Screening every five years safe for women who test negative for HPV, study confirms – King’s College London
Editorial: HPV screening for cervical cancer is reaching maturity – The BMJ
Related WHO Guidance:
News release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization
Related USPSTF Guidance: Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA
Covid-19: US hospitals continued to perform unnecessary surgeries during pandemic.
9 Jun, 2022 | 11:22h | UTCCovid-19: US hospitals continued to perform unnecessary surgeries during pandemic – The BMJ
Original Report: Lown Institute. Hospital overuse during covid. 17 May 2022
Sex differences in clinical characteristics, management strategies, and outcomes of STEMI With COVID-19.
9 Jun, 2022 | 11:24h | UTCEditorial: STEMIs and a Closer Look at MINOCA During the COVID-19 Pandemic – JSCAI
Video: Conversations in Interventional Cardiology: NACMI Registry
Commentary: Mystery MINOCA? Many COVID STEMIs Have No Culprit Lesion – TCTMD
Statement on initial antimicrobial treatment of sepsis.
8 Jun, 2022 | 11:17h | UTCStatement on initial antimicrobial treatment of sepsis – Faculty of Intensive Care Medicine
Commentary on Twitter
🚨Statement on initial antimicrobial treatment of sepsis🚨
Full statement and documents available➡️ https://t.co/jWexX1VDDd @AoMRC pic.twitter.com/kQdJrZ2hOA
— FICMNews (@FICMNews) June 4, 2022
RCT: Effect of electronic symptom monitoring on patient-reported outcomes among patients with metastatic cancer.
8 Jun, 2022 | 11:14h | UTCEffect of Electronic Symptom Monitoring on Patient-Reported Outcomes Among Patients With Metastatic Cancer: A Randomized Clinical Trial – JAMA (free for a limited period)
Related:
Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial – Nature Medicine (if the link is paywalled, try this one)
Key components of successful digital remote monitoring in oncology – Nature Medicine
Cross sectional study: accuracy difference of noninvasive blood pressure measurements by sex and height.
8 Jun, 2022 | 11:11h | UTCAccuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height – JAMA Network Open
Invited Commentary: Sex Differences in Blood Pressure—A Measured Relook at Measures
Commentary on Twitter
This cross-sectional study found non-invasive blood pressure accuracy is influenced by sex, with the brachial cuff greatly underestimating the true aortic systolic blood pressure in females, but not in males, mostly mediated by height differences. https://t.co/7Ubk8ve2ic
— JAMA Network Open (@JAMANetworkOpen) June 7, 2022
‘Helicopter research’ comes under fire at Cape Town conference – statement presses for equity when scientists from wealthy nations do research in poorer ones.
8 Jun, 2022 | 11:11h | UTC‘Helicopter research’ comes under fire at Cape Town conference – Science
Reducing SARS-CoV-2 in shared indoor air.
8 Jun, 2022 | 11:07h | UTCReducing SARS-CoV-2 in Shared Indoor Air – JAMA
Association of estimated GFR calculated using race-free equations with kidney failure and mortality by black vs non-black race.
8 Jun, 2022 | 11:12h | UTCEditorial: Race-Free Estimation of Kidney Function: Clearing the Path Toward Kidney Health Equity
Landmark articles suggest eliminating race in the estimation of kidney function.
Expert panel recommends against use of race in assessment of kidney function – STAT
M-A: Efficacy and harms of tocilizumab for the treatment of COVID-19 patients.
8 Jun, 2022 | 11:06h | UTC
M-A: Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19.
8 Jun, 2022 | 11:09h | UTCRelated:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
Commentary on Twitter
🆕💥💥Systematic review & meta-analysis @OFIDJournal Intensified anticoagulation has NO effect on mortality among hospitalised #COVID19 & ⬆️bleeding
Possible signal of mortality reduction for non-ICU patients although with low precision& high heterogeneity https://t.co/OqLYScxK53— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 7, 2022
Systematic Review: Cannabis-based products for chronic pain.
7 Jun, 2022 | 11:47h | UTCCannabis-Based Products for Chronic Pain: A Systematic Review – Annals of Internal Medicine
Annals Video Summary: Cannabis-Based Products for Chronic Pain: A Systematic Review
Summary for Patients: Cannabis-Based Products for Chronic Pain
Related:
Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders
M-A: Birth outcomes of neonates exposed to marijuana in utero.
Cannabis-related allergies: an international overview and consensus recommendations.
Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.
Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.
Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.
Guideline: Medical cannabis or cannabinoids for chronic pain.
NICE Guideline: Cannabis-Based Medicinal Products
Short Review: Drug Interactions with Cannabinoids
Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain
Review: Considerations for cannabinoids in perioperative care by anesthesiologists.
Review: Cannabis-based Medicines and the Perioperative Physician
Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know


