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RCT: Marine Omega-3 Fatty acid supplementation does not reduce the incidence of dry eye disease in healthy adults.

10 Jun, 2022 | 12:25h | UTC

Efficacy of Marine ω-3 Fatty Acid Supplementation vs Placebo in Reducing Incidence of Dry Eye Disease in Healthy US Adults: A Randomized Clinical Trial – JAMA Ophthalmology (free for a limited period)

Invited Commentary: Another Disappointment for ω-3 Fatty Acid and Dry Eye Disease – JAMA Ophthalmology (free for a limited period)

 

Commentary on Twitter

 


Another study suggests the Omicron variant is associated with a reduced risk of Multisystem Inflammatory Syndrome in Children compared to previous SARS-CoV-2 variants.

10 Jun, 2022 | 12:38h | UTC

Risk and Phenotype of Multisystem Inflammatory Syndrome in Vaccinated and Unvaccinated Danish Children Before and During the Omicron Wave – JAMA Pediatrics

Related study: Severity and Incidence of Multisystem Inflammatory Syndrome in Children During 3 SARS-CoV-2 Pandemic Waves in Israel – JAMA AND Commentary: Kids’ COVID syndrome—MIS-C—less severe in Omicron – CIDRAP

 

Commentary on Twitter

 


Cohort Study: Neurodevelopmental outcomes at 1 year in infants of mothers who tested positive for SARS-CoV-2 during pregnancy.

10 Jun, 2022 | 12:14h | UTC

Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy – JAMA Network Open

Commentaries:

Is It Exposure to the Pandemic or to Maternal SARS-CoV-2 Infection That Is Adversely Affecting Early Childhood Neurodevelopment? – JAMA Network Open

Expert reaction to observational study of mothers who tested positive for SARS-CoV-2 during pregnancy and neurodevelopmental outcomes in their children at 1 year – Science Media Centre

 

Commentary on Twitter

 


M-A: Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections.

10 Jun, 2022 | 12:00h | UTC

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: Update of a living systematic review and meta-analysis – PLOS Medicine

 


Review: The burden and risks of emerging complications of diabetes mellitus.

10 Jun, 2022 | 12:04h | UTC

The burden and risks of emerging complications of diabetes mellitus – Nature Reviews Endocrinology

 

Commentary on Twitter

 


Guidance Statement: Surgical triage and timing for patients with COVID undergoing thoracic surgery.

10 Jun, 2022 | 11:58h | UTC

Surgical Triage and Timing for Patients with COVID: A Guidance Statement from the Society of Thoracic Surgeons – Annals of Thoracic Surgery

 


Review: Pathophysiology and mechanism of long COVID.

10 Jun, 2022 | 11:55h | UTC

Pathophysiology and mechanism of long COVID: a comprehensive review – Annals of Medicine

 


[Preprint] Largest study to date on long COVID identifies a broad list of diagnoses.

10 Jun, 2022 | 11:53h | UTC

Study Commentary: Largest study to date on long COVID identifies a broad list of diagnoses – News Medical

Original Study: Understanding Post-Acute Sequelae of SARS-CoV-2 Infection through Data-Driven Analysis with Longitudinal Electronic Health Records: Findings from the RECOVER Initiative – medRxiv

 

Commentary on Twitter

 


NICE Guideline: Gout diagnosis and management.

9 Jun, 2022 | 11:35h | UTC

Gout: diagnosis and management – National Institute for Health and Care Excellence

 


Study shows a person’s height impacts their risk of multiple diseases.

9 Jun, 2022 | 11:34h | UTC

News Release: A person’s height impacts their risk of multiple diseases – Public Library of Science

Original Study: A multi-population phenome-wide association study of genetically-predicted height in the Million Veteran Program – PLOS Genetics

 


CDC Report: Pediatric melatonin ingestions in the US.

9 Jun, 2022 | 11:32h | UTC

Pediatric Melatonin Ingestions — United States, 2012–2021 – Morbidity and Mortality Weekly Report

Commentaries:

Thousands of kids are getting sick from downing melatonin pills – NPR

Melatonin poisoning reports are up in kids, study says – Associated Press

Melatonin Overdoses Among Kids Are Up 530%, New Research Finds – TIME

Reports of melatonin poisoning in kids have increased 530% since 2012 – Yahoo News

 

Commentary on Twitter

 


[News release – not published yet] Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn.

9 Jun, 2022 | 11:31h | UTC

Women not being routinely informed that a common anesthetic may lessen contraception effectiveness, doctors warn – The European Society of Anaesthesiology and Intensive Care (ESAIC)

Commentary: Women in UK ‘seldom’ told drug used in surgery can impede contraception – The Guardian

 


Review: Deprescribing in palliative cancer care.

9 Jun, 2022 | 11:28h | UTC

Deprescribing in Palliative Cancer Care – Life

 


Screening every five years safe for women who test negative for HPV, study confirms.

9 Jun, 2022 | 11:26h | UTC

News Release: Screening every five years safe for women who test negative for HPV, study confirms – King’s College London

Original Study: Extension of cervical screening intervals with primary human papillomavirus testing: observational study of English screening pilot data – The BMJ

Editorial: HPV screening for cervical cancer is reaching maturity – The BMJ

Related WHO Guidance:

News release: New recommendations for screening and treatment to prevent cervical cancer – World Health Organization

See guidance: WHO guideline for screening and treatment of cervical pre-cancer lesions for cervical cancer prevention – World Health Organization

Related USPSTF Guidance: Screening for Cervical Cancer: US Preventive Services Task Force Recommendation Statement – JAMA

 


Covid-19: US hospitals continued to perform unnecessary surgeries during pandemic.

9 Jun, 2022 | 11:22h | UTC

Covid-19: US hospitals continued to perform unnecessary surgeries during pandemic – The BMJ

Original Report: Lown Institute. Hospital overuse during covid. 17 May 2022

 


Sex differences in clinical characteristics, management strategies, and outcomes of STEMI With COVID-19.

9 Jun, 2022 | 11:24h | UTC

Sex Differences in Clinical Characteristics, Management Strategies, and Outcomes of STEMI With COVID-19: NACMI Registry – JSCAI

Editorial: STEMIs and a Closer Look at MINOCA During the COVID-19 Pandemic – JSCAI

Video: Conversations in Interventional Cardiology: NACMI Registry

News Release: NACMI: International COVID-19 registry finds significant increased risk of in-hospital mortality for STEMI patients with COVID-19 compared to pre-pandemic – Society for Cardiovascular Angiography & Interventions

Commentary: Mystery MINOCA? Many COVID STEMIs Have No Culprit Lesion – TCTMD

 


Statement on initial antimicrobial treatment of sepsis.

8 Jun, 2022 | 11:17h | UTC

Statement on initial antimicrobial treatment of sepsis – Faculty of Intensive Care Medicine

 

Commentary on Twitter

 


RCT: Effect of electronic symptom monitoring on patient-reported outcomes among patients with metastatic cancer.

8 Jun, 2022 | 11:14h | UTC

Effect of Electronic Symptom Monitoring on Patient-Reported Outcomes Among Patients With Metastatic Cancer: A Randomized Clinical Trial – JAMA (free for a limited period)

Related:

Digital remote monitoring plus usual care versus usual care in patients treated with oral anticancer agents: the randomized phase 3 CAPRI trial – Nature Medicine (if the link is paywalled, try this one)

Key components of successful digital remote monitoring in oncology – Nature Medicine

Electronic Health Interventions for Patients With Breast Cancer: Systematic Review and Meta-Analyses – Journal of Clinical Oncology

Efficiency of Electronic Health Record Assessment of Patient-Reported Outcomes After Cancer Immunotherapy: A Randomized Clinical Trial – JAMA Network Open

 


Cross sectional study: accuracy difference of noninvasive blood pressure measurements by sex and height.

8 Jun, 2022 | 11:11h | UTC

Accuracy Difference of Noninvasive Blood Pressure Measurements by Sex and Height – JAMA Network Open

Invited Commentary: Sex Differences in Blood Pressure—A Measured Relook at Measures

 

Commentary on Twitter

 


‘Helicopter research’ comes under fire at Cape Town conference – statement presses for equity when scientists from wealthy nations do research in poorer ones.

8 Jun, 2022 | 11:11h | UTC

‘Helicopter research’ comes under fire at Cape Town conference – Science

 


Reducing SARS-CoV-2 in shared indoor air.

8 Jun, 2022 | 11:07h | UTC

Reducing SARS-CoV-2 in Shared Indoor Air – JAMA

 


Association of estimated GFR calculated using race-free equations with kidney failure and mortality by black vs non-black race.

8 Jun, 2022 | 11:12h | UTC

Association of Estimated GFR Calculated Using Race-Free Equations With Kidney Failure and Mortality by Black vs Non-Black Race – JAMA

Editorial: Race-Free Estimation of Kidney Function: Clearing the Path Toward Kidney Health Equity

News Release: Kidney failure experts recommend new tool that eliminates race as a determining factor for diagnosis – University of Alabama at Birmingham

Landmark articles suggest eliminating race in the estimation of kidney function.

Expert panel recommends against use of race in assessment of kidney function – STAT

A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease – American Journal of Kidney Diseases

 


M-A: Efficacy and harms of tocilizumab for the treatment of COVID-19 patients.

8 Jun, 2022 | 11:06h | UTC

Efficacy and harms of tocilizumab for the treatment of COVID-19 patients: A systematic review and meta-analysis – PLOS One

 


M-A: Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19.

8 Jun, 2022 | 11:09h | UTC

Efficacy and safety of intensified versus standard prophylactic anticoagulation therapy in patients with Covid-19: a systematic review and meta-analysis – Open Forum Infectious Diseases

Related:

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?

 

Commentary on Twitter

 


Systematic Review: Cannabis-based products for chronic pain.

7 Jun, 2022 | 11:47h | UTC

Cannabis-Based Products for Chronic Pain: A Systematic Review – Annals of Internal Medicine

Annals Video Summary: Cannabis-Based Products for Chronic Pain: A Systematic Review

Summary for Patients: Cannabis-Based Products for Chronic Pain

Related:

Podcast: #338 LIVE! Medical Cannabis: Is it still dope? – The Curbsiders

Medicinal Cannabis for Chronic Pain: The Bermuda Triangle of Low Quality Studies, Countless Meta-analyses and Conflicting Recommendations – European Journal of Pain

RCT: Effect of medical marijuana card ownership on pain, insomnia, and affective disorder symptoms in adults.

Cohort Study: Long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife.

AHA Scientific Statement | How does cannabis use affect brain health? Caution advised, more research needed.

M-A: Birth outcomes of neonates exposed to marijuana in utero.

Cannabis-related allergies: an international overview and consensus recommendations.

Review: Cannabis-based medicines and medical cannabis for chronic neuropathic pain.

Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions.

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain.

The International Cannabis Toolkit (iCannToolkit): a multidisciplinary expert consensus on minimum standards for measuring cannabis use.

Cannabis products are being sold as sleep remedies – here’s the evidence about their effectiveness.

Guideline: Medical cannabis or cannabinoids for chronic pain.

Cannabis and Cannabinoid Analgesia position statement – “Due to the lack of high-quality clinical evidence, the IASP does not currently endorse general use of cannabis and cannabinoids for pain relief.”

NICE Guideline: Cannabis-Based Medicinal Products

Consensus recommendations for perioperative management of cannabis and cannabinoid-based medicine users

Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain – Agency for Healthcare Research and Quality

Short Review: Drug Interactions with Cannabinoids

Meta-Analysis: Cannabinoids Not Effective for Cancer-Related Pain

Review: Considerations for cannabinoids in perioperative care by anesthesiologists.

Review: Cannabis-based Medicines and the Perioperative Physician

Study: Cannabis Use Disorder May Increase the Risk of Cardiovascular Events in Major Elective Surgeries

Perspective: If You Smoke Pot, Your Anesthesiologist Needs To Know

Perioperative Care of Cannabis Users: A Comprehensive Review of Pharmacological and Anesthetic Considerations

 


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