Editor's Choice
Cohort Study | Association of the “weekend warrior” and other leisure-time physical activity patterns with all-cause and cause-specific mortality.
6 Jul, 2022 | 11:53h | UTCAssociation of the “Weekend Warrior” and Other Leisure-time Physical Activity Patterns With All-Cause and Cause-Specific Mortality: A Nationwide Cohort Study – JAMA Internal Medicine (free for a limited period)
M-A | Effectiveness of interventions to improve drinking water, sanitation, and handwashing with soap on risk of diarrheal disease in children in low-income and middle-income settings.
6 Jul, 2022 | 11:56h | UTC
Commentary on Twitter
WASH meta-analysis in @TheLancet
Effectiveness of WASH interventions on child diarrhoea in LMICshttps://t.co/yVtoyattQd
How effective are
– water supply (by level of service)
– POU water treatment (by type)
– sanitation (by LoS)
– handwashing with soapRead to find out!
— Environmental Health Group, LSHTM (@LSHTM_EHG) July 1, 2022
RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.
6 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR
— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022
Review | The vaccine-hesitant moment.
6 Jul, 2022 | 11:49h | UTCThe Vaccine-Hesitant Moment – New England Journal of Medicine
FDA orders Juul to remove all its e-cigarettes from US market.
6 Jul, 2022 | 11:46h | UTCFDA orders Juul to remove all its e-cigarettes from US market – The BMJ
See also:
FDA orders all Juul e-cigarettes off the market – POLITICO
The FDA orders Juul to pull all of its vaping products from the U.S. market – NPR
FDA orders Juul Labs to remove products from US market – CNN
FDA News Release: FDA Denies Authorization to Market JUUL Products – U.S. Food & Drug Administration
Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.
6 Jul, 2022 | 11:48h | UTCPoliticians live longer than the populations they represent: new research.
6 Jul, 2022 | 11:44h | UTCPoliticians live longer than the populations they represent: new research – The Conversation
WHO Guideline for the treatment of visceral leishmaniasis in HIV co-infected patients in East Africa and South-East Asia.
5 Jul, 2022 | 12:22h | UTCWHO Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV.
5 Jul, 2022 | 12:23h | UTCM-A | Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital.
5 Jul, 2022 | 12:19h | UTCIndeterminate pediatric acute liver failure: clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022.
5 Jul, 2022 | 12:09h | UTCRelated:
Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)
Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization
Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)
Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology
What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science
Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT
Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC
Hepatitis outbreak in children: What do we know so far? – Imperial College London
Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Association between hypotension during 24 h ambulatory blood pressure monitoring and reflex syncope.
5 Jul, 2022 | 12:18h | UTC
Commentary on Twitter
Association between hypotension during 24 h ambulatory blood pressure monitoring and reflex syncope: the SynABPM 1 study.https://t.co/tMlGHQ4Csm#hypotension #bloodpressure #cardiotwitter @ESC_Journals @escardio pic.twitter.com/JpX6kxwj1R
— EHJ Editor-in-Chief (@ehj_ed) July 2, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license
Review | Bridging knowledge gaps in the diagnosis and management of neuropsychiatric sequelae of COVID-19.
5 Jul, 2022 | 12:07h | UTC
Commentary on Twitter
Neuropsychiatric post-acute sequelae of #COVID19 appear common but heterogeneous. Studies such as the NIH RECOVER initiative are needed to clarify neuropsychiatric PASC epidemiology, pathophysiology, mechanisms of injury and targets for intervention. https://t.co/AjwoLrZXc7
— JAMA Psychiatry (@JAMAPsych) July 1, 2022
Key studies published in 2021 related to primary prevention of atherosclerotic cardiovascular disease.
5 Jul, 2022 | 12:12h | UTCHighlights in ASCVD Primary Prevention for 2021 – Journal of the American Heart Association
Review | Preoperative evaluation and management of patients with select chronic gastrointestinal, liver, and renal diseases.
5 Jul, 2022 | 12:16h | UTCRelated:
Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings
Preoperative Management of Surgical Patients Using Dietary Supplements – Mayo Clinic Proceedings
Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings
Preoperative Cardiac Risk Assessment – Mayo Clinic Proceedings
Preoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Perioperative Venous Thromboembolism Prophylaxis – Mayo Clinic Proceedings
The Lancet Series | Road Safety 2022
5 Jul, 2022 | 12:13h | UTCHomepage: Road Safety 2022 (free registration required for all articles)
Editorial: Road safety: more than reducing injuries
The political and social contexts of global road safety: challenges for the next decade
Saving lives through road safety risk factor interventions: global and national estimates
Commentaries:
Review | Prevention and treatment of Monkeypox.
5 Jul, 2022 | 12:05h | UTCPrevention and Treatment of Monkeypox – Drugs
NICE Guideline | Treatment and management of depression in adults.
4 Jul, 2022 | 13:02h | UTCDepression in adults: treatment and management – National Institute for Health and Care Excellence
NICE Guideline | Management of multiple sclerosis in adults.
4 Jul, 2022 | 13:00h | UTCMultiple sclerosis in adults: management – National Institute for Health and Care Excellence
Review | Cough hypersensitivity and chronic cough.
4 Jul, 2022 | 12:59h | UTCCough hypersensitivity and chronic cough – Nature Reviews Disease Primers (if the link is paywalled, try this one)
See also: Infographic (if the link is paywalled, try this one)
Commentary on Twitter
#Cough is mediated by a complex set of neurobiological processes involving the peripheral nervous system, brainstem and higher brain. #ChronicCoughhttps://t.co/DGgjk2Iyji pic.twitter.com/nrmJne7Ir8
— Nature Reviews Disease Primers (@DiseasePrimers) July 2, 2022
Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug.
4 Jul, 2022 | 12:57h | UTCBad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug – Science
See also: SARS-CoV-2 can evade Paxlovid by multiple mechanisms – News Medical
Guideline Synopsis | Evaluation and diagnosis of chest pain.
4 Jul, 2022 | 12:49h | UTCEvaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)
Original Guideline:
News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released
Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain
Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology
Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD
Opinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.
4 Jul, 2022 | 12:53h | UTCFDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT
Antibodies to combat viral infections: development strategies and progress.
4 Jul, 2022 | 12:51h | UTCAntibodies to combat viral infections: development strategies and progress – Nature Reviews Drug Discovery (if the link is paywalled, try this one in PMC)
RCT | Immobilization of torus fractures of the wrist in children.
4 Jul, 2022 | 12:46h | UTC
Commentary from the author on Twitter (thread – click for more)
The FORCE study is in @TheLancet – https://t.co/oyYvMMxjln has awesome stuff to implement result – ED pathway, animations & patient info leaflets (multiple languages).
Thanks to @PERUKItweep and everyone who made it possible. https://t.co/Wq67MgcQhB pic.twitter.com/mrA03tGzCs
— Dan Perry (@MrDanPerry) July 1, 2022