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Study | AI use in lung cancer screening enhances prediction of lung cancer death, CVD death, and all-cause death

1 Aug, 2023 | 14:31h | UTC

AI Body Composition in Lung Cancer Screening: Added Value Beyond Lung Cancer Detection – Radiology (free for a limited period)

Commentary: Study: AI Assessment of Chest CT May Predict Multiple Mortality Risks – Diagnostic Imaging

 


Opinion | Bad science needs to be called out: the medical profession loses trust when bad studies are used to promote policy

1 Aug, 2023 | 14:29h | UTC

Bad Science Needs to Be Called Out – Sensible Medicine

Related: Did Republicans die more during the pandemic bc they didn’t get the vax? – By Dr. Vinay Prassad

Original Study: Excess Death Rates for Republican and Democratic Registered Voters in Florida and Ohio During the COVID-19 Pandemic – JAMA Internal Medicine

 


Critical Appraisal | Did Republicans die more during the pandemic bc they didn’t get the vax?

1 Aug, 2023 | 14:28h | UTC

Did Republicans die more during the pandemic bc they didn’t get the vax? – By Dr. Vinay Prassad

Related: Bad Science Needs to Be Called Out – Sensible Medicine

Original Study: Excess Death Rates for Republican and Democratic Registered Voters in Florida and Ohio During the COVID-19 Pandemic – JAMA Internal Medicine

 


BTS Guideline for pleural disease

31 Jul, 2023 | 14:44h | UTC

British Thoracic Society Guideline for pleural disease – Thorax

 


BTS Clinical Statement on pleural procedures

31 Jul, 2023 | 14:42h | UTC

British Thoracic Society Clinical Statement on pleural procedures – Thorax

 


Opinion Video | Critical analysis of the data behind Covid-19 booster shots

31 Jul, 2023 | 14:40h | UTC

“FLAWED Booster data was used by FDA for Mass Vax Campaign & We PROVE it in our new PAPER” – YouTube Video by Dr Vinay Prassad

Original Publication: Correspondence | Potential “healthy vaccinee bias” in a study of BNT162b2 vaccine against Covid-19

 


Observational Study | More data suggesting Rosuvastatin 10mg/Ezetimibe 10mg combo may be an alternative to Rosuvastatin 20mg

31 Jul, 2023 | 14:38h | UTC

Combination Lipid-Lowering Therapy in Patients Undergoing Percutaneous Coronary Intervention – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Statins post PCI: Moderate intensity plus ezetimibe may be preferable – Cardiology News

Combination Lipid-Lowering Therapy After PCI – American College of Cardiology

Related: Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.

 

Commentary on Twitter

 


M-A | Various exercise training modes reduce resting blood pressure, isometric exercise most effective

31 Jul, 2023 | 14:35h | UTC

Exercise training and resting blood pressure: a large-scale pairwise and network meta-analysis of randomised controlled trials – British Journal of Sports Medicine

News Release: Static isometric exercise, such as wall sits, best for lowering blood pressure – BMJ Newsroom

Commentary: Wall squats and planks best at lowering blood pressure – BBC

 


UNESCO calls for global ban on smartphones in schools

28 Jul, 2023 | 14:26h | UTC

Report: Technology in education – UNESCO

News Releases:

UNESCO calls for global ban on smartphones in schools – UN News

Smartphones in school? Only when they clearly support learning – UNESCO

Commentary: ‘Put learners first’: Unesco calls for global ban on smartphones in schools – The Guardian

 


WHO updates guidelines on fats and carbohydrates

28 Jul, 2023 | 14:25h | UTC

News Release: WHO updates guidelines on fats and carbohydrates – World Health Organization

Guidelines:

Saturated fatty acid and trans-fatty acid intake for adults and children: WHO guideline – World Health Organization

Total fat intake for the prevention of unhealthy weight gain in adults and children: WHO guideline – World Health Organization

Carbohydrate intake for adults and children: WHO guideline – World Health Organization

 

Commentary on Twitter (thread – click for more)

 


New WHO lists of essential medicines

28 Jul, 2023 | 14:23h | UTC

News Release: WHO endorses landmark public health decisions on Essential Medicines for Multiple Sclerosis – World Health Organization

Lists of Essential Medicines

Model Lists of Essential Medicines – World Health Organization

Model Lists of Essential Medicines for Children – World Health Organization

 

Commentary on Twitter

 


Study | Only 11% of sports supplements listing botanical ingredients accurately declare contents, 12% contain FDA-prohibited stimulants

28 Jul, 2023 | 14:21h | UTC

Presence and Quantity of Botanical Ingredients With Purported Performance-Enhancing Properties in Sports Supplements – JAMA Network Open

Commentaries:

Ensuring the Safety and Value of Supplements – JAMA Network Open

Sports Supplements Can Be Contaminated with Botanical Stimulants and Anabolic Agents – NEJM Journal Watch

 


BMJ Investigation | Medical royal colleges receive millions from drug and medical devices companies

28 Jul, 2023 | 14:19h | UTC

Medical royal colleges receive millions from drug and medical devices companies – The BMJ

News Release: Medical royal colleges receive millions from drug/medical device companies – BMJ Newsroom

 

Commentary on Twitter

 


JAMA guidance for authors, peer reviewers, and editors on use of AI, language models, and chatbots

28 Jul, 2023 | 14:18h | UTC

Guidance for Authors, Peer Reviewers, and Editors on Use of AI, Language Models, and Chatbots – JAMA

See also, just published: New recommendations of the International Committee of Medical Journal Editors: use of artificial intelligence – European Heart Journal

Related

Comparing scientific abstracts generated by ChatGPT to real abstracts with detectors and blinded human reviewers – npj Digital Medicine

ChatGPT et al? Not So Fast, Say Journal Editors – TCTMD

Chat GPT will change Medicine – Vinay Prasad’s Observations and Thoughts

ChatGPT has many uses. Experts explore what this means for healthcare and medical research – The Conversation

Can artificial intelligence help for scientific writing? – Critical Care

Artificial intelligence in academic writing: a paradigm-shifting technological advance

Perspective | Generating scholarly content with ChatGPT: ethical challenges for medical publishing

ChatGPT and the future of medical writing (ChatGPT itself wrote this paper)

Nonhuman “Authors” and Implications for the Integrity of Scientific Publication and Medical Knowledge – JAMA

ChatGPT is fun, but not an author – Science

Tools such as ChatGPT threaten transparent science; here are our ground rules for their use – Nature

ChatGPT listed as author on research papers: many scientists disapprove – Nature

Abstracts written by ChatGPT fool scientists

 


Study | New deep learning model effectively detects type 2 diabetes from chest X-rays

28 Jul, 2023 | 14:15h | UTC

Opportunistic detection of type 2 diabetes using deep learning from frontal chest radiographs – Nature Communications

 

Commentary on Twitter

 


Position Paper | Prioritizing deprescribing in fall prevention strategies

28 Jul, 2023 | 14:12h | UTC

European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation – European Geriatric Medicine

Original Guideline: World guidelines for falls prevention and management for older adults: a global initiative – Age and Ageing

 


A new global definition of Acute Respiratory Distress Syndrome

27 Jul, 2023 | 13:14h | UTC

A New Global Definition of Acute Respiratory Distress Syndrome – American Journal of Respiratory and Critical Care Medicine

 

Commentary on Twitter

 


WHO world drowning prevention day 2023

27 Jul, 2023 | 13:12h | UTC

World Drowning Prevention Day 2023 – World Health Organization

Report: Hidden depths: the global investment case for drowning prevention – World Health Organization

Related:

Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update

Tracing the emergence of drowning prevention on the global health and development agenda: a policy analysis – The Lancet Global Health

WHO Guideline on the prevention of drowning through provision of day-care and basic swimming and water safety skills – World health Organization

Wilderness Medical Society Clinical Practice Guidelines for the Treatment and Prevention of Drowning: 2019 Update

Prevention of Drowning – Pediatrics

The burden of unintentional drowning: global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study – Injury Prevention

Preventing drowning: an implementation guide – World Health Organization

Global report on drowning: preventing a leading killer – World Health Organization

Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide

 

Commentary on Twitter (thread – click for more)

 


Review | State of shock: contemporary vasopressor and inotrope use in cardiogenic shock

27 Jul, 2023 | 13:11h | UTC

State of Shock: Contemporary Vasopressor and Inotrope Use in Cardiogenic Shock – Journal of the American Heart Association

 


RCT – 2ry Analysis | Elevated intracranial bleeding risk with low-dose aspirin in older adults

27 Jul, 2023 | 13:09h | UTC

Low-Dose Aspirin and the Risk of Stroke and Intracerebral Bleeding in Healthy Older People: Secondary Analysis of a Randomized Clinical Trial – JAMA Network Open

See also: Visual Abstract

News Release: Low dose aspirin won’t help some older adults trying to avoid a stroke: study – Monash University

Commentary: Daily aspirin doesn’t prevent strokes in older, healthy people after all – The Conversation

Original Study: Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly

Related Guideline: USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.

Related Randomized Trials:

Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease

Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes

Related Meta-Analysis:

Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events

Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups – BMC Medicine

Related Opinions:

Aspirin for Primary Prevention: Is This the End of the Road?

Evidence evolving on aspirin as prevention – ACP Internist

#347 USPSTF Update: Aspirin for Primary Prevention of CVD – The Curbsiders

 


RCT | Limited antibiotic efficacy in children with sinusitis lacking nasopharyngeal pathogens

27 Jul, 2023 | 13:08h | UTC

Identifying Children Likely to Benefit From Antibiotics for Acute Sinusitis: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Acute Bacterial Sinusitis: Limitations of Test-Based Treatment – JAMA (free for a limited period)

News Release: Bacterial testing in kids with sinusitis could slash antibiotic use – University of Pittsburgh

Commentary: Trial suggests bacterial test could reduce antibiotics in kids with sinusitis – CIDRAP

 

Commentary on Twitter

 


RCT | Cervical pessary fails to prevent preterm birth in short cervix singleton pregnancies

27 Jul, 2023 | 13:06h | UTC

Cervical Pessary for Prevention of Preterm Birth in Individuals With a Short Cervix: The TOPS Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: The Vexing Problem of Preterm Birth Prevention – JAMA (free for a limited period)

See also: Visual Abstract

News Release: Cervical pessary no more effective than usual care in preventing preterm birth risk – NIH News Releases

 


RCT | Pitavastatin effective in the primary prevention of cardiovascular disease in HIV-infected individuals

26 Jul, 2023 | 13:35h | UTC

Pitavastatin to Prevent Cardiovascular Disease in HIV Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Pitavastatin lowers risk of cardiovascular events in people living with HIV – Aidsmap

Statins reduce cardiovascular risk in people living with HIV, new global study finds – STAT

Pitavastatin Cuts MACE in HIV-Infected Patients: REPRIEVE – TCTMD

 

Commentary on Twitter

 


ISCHEMIA Trial 2ry Analysis | Patients with CCD and daily/weekly angina seem to benefit most from complete revascularization

26 Jul, 2023 | 13:33h | UTC

Complete Revascularization and Angina-Related Health Status in the ISCHEMIA Trial – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries:

Complete Revascularization and Angina-Related Health Status – American College of Cardiology

More Angina Relief With Complete Revascularization in Stable CAD: ISCHEMIA – TCTMD

Related/Original Articles:

Follow-up of the ISCHEMIA trial | Similar survival after invasive vs. conservative management of stable coronary disease.

ISCHEMIA Trial: Health-Status Outcomes with Initial Invasive vs. Conservative Care in Stable Coronary Disease

ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease

ISCHEMIA Trial: Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease

ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease

 


Perspective | What does it mean to discover a coronary blockage?

26 Jul, 2023 | 13:31h | UTC

Chapter 1: What Does it Mean to Discover a Coronary Blockage? – By Dr John Mandrola

Chapter 2: On the meaning of a coronary blockage – By Dr John Mandrola

 


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