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Position Paper | Diagnosis, prevention and treatment of common shoulder injuries in sport

10 Feb, 2023 | 14:01h | UTC

Diagnosis, prevention and treatment of common shoulder injuries in sport: grading the evidence – a statement paper commissioned by the Danish Society of Sports Physical Therapy (DSSF) – British Journal of Sports Medicine

 

Commentary on Twitter

 


Resistant hypertension: a stepwise approach

10 Feb, 2023 | 13:58h | UTC

Resistant hypertension: A stepwise approach – Cleveland Clinic Journal of Medicine

 


Brief Review | Mpox — A rapidly evolving disease

10 Feb, 2023 | 13:56h | UTC

Mpox—A Rapidly Evolving Disease – JAMA Dermatology

Related:

Surveillance, case investigation and contact tracing for mpox (monkeypox): interim guidance, 22 December 2022 – World Health Organization

Rapid review on monkeypox policies among the G20 nations: relevance to policy and practitioner – F1000 Research

Clinical features and management of individuals admitted to hospital with monkeypox and associated complications across the UK: a retrospective cohort study – The Lancet Infectious Diseases

Monkeypox (hMPXV infection): A practical review – American Journal of Medicine

Monkeypox in pregnancy: virology, clinical presentation, and obstetric management – American Journal of Obstetrics & Gynecology

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

Monkeypox – The Lancet

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

Monkeypox – New England Journal of Medicine

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

 


RCT | Argatroban plus Alteplase not better than Alteplase alone in patients with acute ischemic stroke

10 Feb, 2023 | 13:59h | UTC

Effect of Argatroban Plus Intravenous Alteplase vs Intravenous Alteplase Alone on Neurologic Function in Patients With Acute Ischemic Stroke: The ARAIS Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 


RCT | AI improves nodule detection on chest radiographs in a health screening population

10 Feb, 2023 | 13:55h | UTC

AI Improves Nodule Detection on Chest Radiographs in a Health Screening Population: A Randomized Controlled Trial – Radiology

Editorial: AI Nodule Detection on Chest Radiographs Using Randomized Controlled Data: The Effect on Clinical Practice – Radiology

News Release: AI Improves Lung Nodule Detection on Chest X-Rays – RSNA News

 


SR | Mechanical plus oral antibiotic bowel preparation may prevent complications in elective colorectal surgery

10 Feb, 2023 | 13:53h | UTC

Preoperative combined mechanical and oral antibiotic bowel preparation for preventing complications in elective colorectal surgery – Cochrane Library

Summary: Can combined mechanical and oral antibiotic bowel preparation reduce the risk of complications after scheduled colon or rectal resections compared with purely mechanical, purely oral antibiotic or no bowel preparation? – Cochrane Library

Related:

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

Meta-Analysis: Effects of Mechanical Bowel Preparation and Oral Antibiotics Before Elective Colorectal Surgery

 


Opinion | Interpreting the results from the first randomized controlled trial of colonoscopy: does it save lives?

10 Feb, 2023 | 13:54h | UTC

Interpreting the results from the first randomised controlled trial of colonoscopy: does it save lives? – BMJ Evidence Based Medicine

Original Study: RCT | Effect of colonoscopy screening on risks of colorectal cancer and related death.

 


RCT | Effectiveness of Mycophenolate Mofetil among patients with progressive IgA nephropathy

10 Feb, 2023 | 13:52h | UTC

Effectiveness of Mycophenolate Mofetil Among Patients With Progressive IgA Nephropathy: A Randomized Clinical Trial – JAMA Network Open

 

Commentary on Twitter

 


SHEA/IDSA/APIC Recommendations | Strategies to prevent healthcare-associated infections through hand hygiene

9 Feb, 2023 | 14:08h | UTC

SHEA/IDSA/APIC Practice Recommendation: Strategies to prevent healthcare-associated infections through hand hygiene: 2022 Update – Infection Control & Hospital Epidemiology

 


RCT | Sublobar resection noninferior to lobal resection for peripheral stage IA non–small-cell lung cancer

9 Feb, 2023 | 14:05h | UTC

Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Less lung tissue removal needed for early-stage cancer, study finds – Weill Cornell Medical College

Related:

Survival outcomes in a prospective randomized multicenter Phase III trial comparing patients undergoing anatomical segmentectomy versus standard lobectomy for non-small cell lung cancer up to 2 cm – Lung Cancer

A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation.

Segmentectomy versus lobectomy in small-sized peripheral non-small-cell lung cancer (JCOG0802/WJOG4607L): a multicentre, open-label, phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

A Meta-Analysis Comparing Lobectomy versus Segmentectomy in Stage I Non-Small Cell Lung Cancer – The Korean Journal of Thoracic and Cardiovascular Surgery

 


Cohort Study | Adverse pregnancy outcomes and long-term risk of ischemic heart disease in mothers

9 Feb, 2023 | 14:02h | UTC

Adverse pregnancy outcomes and long term risk of ischemic heart disease in mothers: national cohort and co-sibling study – The BMJ

News Release: Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease – News Medical/BMJ

Commentary: Complications during pregnancy linked to a higher risk of heart disease, study finds – CNN

Related:

Risk and trajectory of premature ischemic CVD in women with a history of pre-eclampsia: a nationwide register-based study

Cohort Study | Pre-eclampsia is associated with increased risk of premature-onset obstructive coronary artery stenosis.

Primary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

Cohort Study: Preeclampsia and Cardiovascular Disease

Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors

All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease

Gestational Hypertension and Future Risk of Cardiovascular Disease

Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents

 


RCT | Pegylated Interferon Lambda reduces hospitalizations in predominantly vaccinated outpatients with Covid-19

9 Feb, 2023 | 14:03h | UTC

Early Treatment with Pegylated Interferon Lambda for Covid-19 – New England Journal of Medicine

News Release: Single-dose treatment reduces risk of COVID-19 hospitalization by half for high-risk patients in a largely vaccinated population – University Health Network

 


[Not published yet] Dual blood thinners under prescribed after minor or warning stroke, especially in women

9 Feb, 2023 | 14:01h | UTC

Dual blood thinners under prescribed after minor or warning stroke, especially in women – American Heart Association

Related:

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ

Dual Antiplatelet Therapy Versus Aspirin in Patients With Stroke or Transient Ischemic Attack: Meta-Analysis of Randomized Controlled Trials – Stroke

Efficacy and Safety of Using Dual Versus Monotherapy Antiplatelet Agents in Secondary Stroke Prevention: Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials – Circulation

Multiple versus fewer antiplatelet agents for preventing early recurrence after ischaemic stroke or transient ischaemic attack – Cochrane Library

 


Case-control study | Effectiveness of a Meningococcal Group B vaccine (4CMenB) in children

9 Feb, 2023 | 13:59h | UTC

Effectiveness of a Meningococcal Group B Vaccine (4CMenB) in Children – New England Journal of Medicine

Commentaries:

NEJM: Effectiveness of pediatric meningococcal B vaccine – MedicalResearch.com

4CMenB Vaccination Effective Against Invasive Meningococcal Disease in Children Under 5 – HealthDay

 

Commentary on Twitter

 


Cohort Study | Outcomes of Meningococcal B disease in children after implementation of routine 4CMenB vaccination

9 Feb, 2023 | 13:57h | UTC

Outcomes of meningococcal serogroup B disease in children after implementation of routine infant 4CMenB vaccination in England: an active, prospective, national surveillance study – The Lancet Child & Adolescent Health

 

Commentary on Twitter

 


RCT | BCG vaccine not effective for preventing COVID-19 and other respiratory tract infections in older adults

9 Feb, 2023 | 13:53h | UTC

Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial – Clinical Microbiology and Infection

News Release: Tuberculosis vaccine does not protect elderly against COVID-19, finds large Dutch study – University Medical Center Utrecht

 

Commentary on Twitter

 


RCT | Pregnancy and neonatal safety of PrEP for HIV prevention initiated during pregnancy vs. afterwards

9 Feb, 2023 | 13:55h | UTC

Pregnancy and neonatal safety outcomes of timing of initiation of daily oral tenofovir disoproxil fumarate and emtricitabine pre-exposure prophylaxis for HIV prevention (CAP016): an open-label, randomised, non-inferiority trial – The Lancet HIV (link to abstract – $ for full-text)

 


Guidance on the use of convalescent plasma to treat immunocompromised patients with COVID-19

9 Feb, 2023 | 13:50h | UTC

Guidance on the use of convalescent plasma to treat immunocompromised patients with COVID-19 – Clinical Infectious Diseases

 


Retrospective Cohort | Survivors of sepsis are at increased risk of late cardiovascular events

8 Feb, 2023 | 12:46h | UTC

Cardiovascular Events Among Survivors of Sepsis Hospitalization: A Retrospective Cohort Analysis – Journal of the American Heart Association

Editorial: Describing Sepsis as a Risk Factor for Cardiovascular Disease – Journal of the American Heart Association

News Release: Sepsis increased risk of heart failure and rehospitalization after hospital discharge – American Heart Association

Commentaries:

Sepsis Emerges as Powerful CVD Risk Factor in Large US Analysis – TCTMD

Cardiovascular Hospitalization Increased After Sepsis Hospitalization – HealthDay

 


RCT | Gefitinib plus MTX not better than MTX alone to treat tubal ectopic pregnancy

8 Feb, 2023 | 12:43h | UTC

Combination of gefitinib and methotrexate to treat tubal ectopic pregnancy (GEM3): a multicentre, randomised, double-blind, placebo-controlled trial – The Lancet

 

Commentary from the author on Twitter (thread – click for more)

Under a Creative Commons Attribution (CC BY 4.0) license

 


Review | Liberation from mechanical ventilation in the cardiac intensive care unit

8 Feb, 2023 | 12:45h | UTC

Liberation From Mechanical Ventilation in the Cardiac Intensive Care Unit – JACC: Advances

 


Review | Management of menopausal symptoms

8 Feb, 2023 | 12:44h | UTC

Management of Menopausal Symptoms: A Review – JAMA (free for a limited period)

Audio Clinical Review: Treatment of Menopausal Symptoms – JAMA

 


RCT | Methylprednisolone vs. immunoglobulins equally effective in PIMS temporally associated with SARS-CoV-2

8 Feb, 2023 | 12:42h | UTC

Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial – The Lancet Child & Adolescent Health

 


Review | Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome

8 Feb, 2023 | 12:38h | UTC

Autonomic dysfunction and postural orthostatic tachycardia syndrome in post-acute COVID-19 syndrome – Nature Reviews Cardiology

 

Commentary on Twitter

 


Video | Malaria — Epidemiology, treatment, and prevention

8 Feb, 2023 | 12:37h | UTC

Malaria — Epidemiology, Treatment, and Prevention | NEJM

 


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