Critical Care & Emergencies (all articles) | Page 84 of 183 | Links Medicus Content Curation & Alerts in Medicine

RECOVERY Pre-print:

Convalescent plasma does not improve survival in patients hospitalised with COVID-19 in this randomised controlled trial involving 11,558 patients:https://t.co/36YZwJNY3Q pic.twitter.com/sKR095n1PC

— Martin Landray (@MartinLandray) March 10, 2021

State of the Art Review | Severe covid-19 pneumonia: pathogenesis and clinical management

11 Mar, 2021 | 08:37h | UTC

Severe covid-19 pneumonia: pathogenesis and clinical management – The BMJ

The role of C-reactive protein as a prognostic marker in COVID-19

10 Mar, 2021 | 08:38h | UTC

The role of C-reactive protein as a prognostic marker in COVID-19 – International Journal of Epidemiology

Pregnancy and COVID: what the data say

10 Mar, 2021 | 08:39h | UTC

Pregnancy and COVID: what the data say – Nature

Restricting daily chest radiography in the ICU: Implementing evidence-based medicine to decrease utilization

9 Mar, 2021 | 02:25h | UTC

Restricting Daily Chest Radiography in the Intensive Care Unit: Implementing Evidence-Based Medicine to Decrease Utilization – Journal of the American College of Radiology

Commentary: Curbing daily use of chest x-ray in ICU cuts major costs – AuntMinnie (free registration required)

Commentary on Twitter

"Changing ordering practices in the adult ICUs to align with established evidence-based guidelines resulted in a 37% decrease in the utilization of portable chest radiography." https://t.co/waUQNdAM2i @JACRJournal pic.twitter.com/eKGDwgWCM8

— Rich Duszak, MD (@RichDuszak) July 9, 2020

RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia

9 Mar, 2021 | 02:29h | UTC

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)

Editorial: Rightsizing Treatment for Pneumonia in Children

Commentary: Five days of antibiotics fine for children with pneumonia – McMaster University

Commentary on Twitter (thread – click for more)

This is fantastic! In outpatient community acquired pneumonia (CAP) a 5 day course of amoxicillin is just as effective as a 10 day course. A small thread follow1/6https://t.co/ewceFEe4gw

— Ricardo Quinonez, MD (@QuinonezRicardo) March 8, 2021

Report: Risk of death from Covid-19 significantly increased in countries where most are overweight

9 Mar, 2021 | 02:52h | UTC

Report: COVID-19 and Obesity: The 2021 Atlas

Commentaries: Covid-19 death rates 10 times higher in countries where most adults are overweight, report finds – CNN AND Covid-19: Highest death rates seen in countries with most overweight populations – The BMJ AND Covid-19: We must tackle obesity and health inequalities in order to build back better – The BMJ Opinion AND COVID-19 Death Rates 10 Times Higher in Countries Where Most Are Overweight – HealthDay

CDC study: Body mass index and risk for COVID-19–related hospitalization, intensive care unit admission, invasive mechanical ventilation, and death

9 Mar, 2021 | 02:54h | UTC

Body Mass Index and Risk for COVID-19–Related Hospitalization, Intensive Care Unit Admission, Invasive Mechanical Ventilation, and Death — United States, March–December 2020 – CDC Morbidity and Mortality Weekly Report

Commentaries: CDC: Obese adults at higher risk for hospitalization, death from COVID-19 – UPI AND Obesity a Big Risk Factor for Severe COVID-19, Study Confirms – HealthDay

Colchicine and COVID-19: a Tale of Two Trials

9 Mar, 2021 | 02:51h | UTC

Colchicine and COVID-19: a Tale of Two Trials – CVCT CardioBrief

Study 1: RECOVERY trial: Colchicine arm stopped for lack of efficacy in patients hospitalized with COVID-19

Study 2: [Preprint] Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19

[Preprint] Systematic review: Characteristics of SARS-CoV-2 reinfection vs. persistent COVID-19

9 Mar, 2021 | 02:44h | UTC

SARS-CoV-2 Sequence Characteristics of COVID-19 Persistence and Reinfection – medRxiv

Commentary: How can physicians distinguish between COVID-19 persistence and SARS-CoV-2 reinfection? – News Medical

Ten things to consider when implementing rationing guidelines during a pandemic

9 Mar, 2021 | 02:46h | UTC

Ten things to consider when implementing rationing guidelines during a pandemic – Intensive Care Medicine

Commentary on Twitter

Rationing in #pandemic? Consider
1⃣identify scarce resources
2⃣exhaust ways to integrate
3⃣be clear/involve public
4⃣prognosis/age
5⃣responsibilities
6⃣pt goals/choice
7⃣disabilities, poverty, racism
8⃣prioritize
9⃣legal coverage
?impact on HCWs#COVID19 https://t.co/iSWVbqH3FY pic.twitter.com/bIoYmsSKQD

— Intens Care Med (@yourICM) March 7, 2021

Cohort study: Elevated blood pressures are common in the emergency department but are they important?

9 Mar, 2021 | 02:04h | UTC

Yes, Your BP Is Up. No, It Doesn’t Matter. – Journal Feed

Original study: Elevated Blood Pressures Are Common in the Emergency Department but Are They Important? A Retrospective Cohort Study of 30,278 Adults – Annals of Emergency Medicine (link to abstract – $ for full-text)

Study: Balanced crystalloids vs. saline in critically ill adults with hyperkalemia or acute kidney injury

9 Mar, 2021 | 02:05h | UTC

Can We Use LR for Hyperkalemia? – Journal Feed

Original study: Balanced Crystalloids versus Saline in Critically Ill Adults with Hyperkalemia or Acute Kidney Injury: Secondary Analysis of a Clinical Trial – American Journal of Respiratory and Critical Care Medicine

Systematic review: High‐flow nasal cannula for respiratory support in adult intensive care patients

7 Mar, 2021 | 19:31h | UTC

High‐flow nasal cannula for respiratory support in adult intensive care patients – Cochrane Library

Summary: High-flow nasal cannulae for breathing support in adult intensive care patients – Cochrane Library

RECOVERY trial: Colchicine arm stopped for lack of efficacy in patients hospitalized with COVID-19

7 Mar, 2021 | 20:16h | UTC

RECOVERY trial closes recruitment to colchicine treatment for patients hospitalised with COVID-19 – University of Oxford

Commentary: Cochicine does not improve mortality in COVID19 – St Emlyn’s

Commentary on Twitter

RECOVERY trial update:

Colchicine arm stopped for lack of efficacy in patients hospitalised with COVID-19.https://t.co/hcn9PytegJ pic.twitter.com/q09eddYXYL

— Martin Landray (@MartinLandray) March 5, 2021

RCT: Azithromycin provides no benefit for community treatment of patients with suspected COVID-19

7 Mar, 2021 | 20:15h | UTC

Azithromycin for community treatment of suspected COVID-19 in people at increased risk of an adverse clinical course in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial – The Lancet

Commentary on Twitter

The PRINCIPLE trial publishes its first peer reviewed paper, showing results from the study of azithromycin as a treatment for Covid-19 in the community. @TheLancet #UrgentCovidResearch #PRINCIPLETrial
?https://t.co/qKRI5PVpQk pic.twitter.com/BVQztDSvSC

— OxPrimaryCareSci (@OxPrimaryCare) March 5, 2021

[Preprint] Genomics and epidemiology of a novel SARS-CoV-2 lineage P.1 – “P.1 may be 1.4–2.2 times more transmissible and 25-61% more likely to evade protective immunity elicited by previous infection with non-P.1 lineages”

7 Mar, 2021 | 20:05h | UTC

Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil – medRxiv

Commentary: Brazil variant can reinfect virus survivors; COVID-19 vaccine antibodies pass into breast milk – Reuters

Diagnosis of non-consensus transient ischemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis

7 Mar, 2021 | 19:32h | UTC

Diagnosis of non-consensus transient ischaemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis – The Lancet

Commentary on Twitter

Some patients present with symptoms that are considered not definitive for TIA (isolated dysarthria, vertigo, etc). Are these patients at risk for later stroke? Fascinating results in @TheLancet from the Oxford Vascular Study@ESOstroke @WorldStrokeOrg https://t.co/l0tJXseE3Y

— Seemant Chaturvedi (@ChaturvediNeuro) March 5, 2021

[Preprint] Increased risk of hospitalization associated with infection with SARS-CoV-2 Lineage B.1.1.7 in Denmark

7 Mar, 2021 | 19:46h | UTC

Increased Risk of Hospitalisation Associated with Infection with SARS-CoV-2 Lineage B.1.1.7 in Denmark – The Lancet

Commentary on Twitter (thread – click for more)

?~64% MORE SEVERE—The already more contagious #B117 variant from ?? is now found to increase risk of #COVID19 hospitalization by 64% versus other strains, says Denmark’s ?? CDC. Denmark sequences every cases—their data is the best, & now most worrisome.? https://t.co/F6w2JYEUnM pic.twitter.com/mngJoTBZtl

— Eric Feigl-Ding (@DrEricDing) March 4, 2021