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Critical Care & Emergencies (all articles)

Brief Review | Optimizing aerosolized therapies in critically ill patients.

11 Jul, 2022 | 12:37h | UTC

Optimising aerosolized therapies in critically ill patients – Intensive Care Medicine (if the link is paywalled, try this one)

 


RCT | 20% albumin vs. plasmalyte in patients with cirrhosis and sepsis-induced hypotension.

11 Jul, 2022 | 12:16h | UTC

A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial] – Journal of Hepatology

 


Review | Understanding and interpreting artificial intelligence, machine learning and deep learning in Emergency Medicine.

11 Jul, 2022 | 12:02h | UTC

Understanding and interpreting artificial intelligence, machine learning and deep learning in Emergency Medicine – Emergency Medicine Journal (free for a limited period)

 


M-A | Fluid resuscitation with balanced crystalloids vs. normal saline in critically ill patients.

11 Jul, 2022 | 12:00h | UTC

Fluid resuscitation with balanced crystalloids versus normal saline in critically ill patients: a systematic review and meta-analysis – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine

Related:

Back to BaSICS – Annals of Emergency Medicine

Effect of Intravenous Fluid Treatment With a Balanced Solution vs 0.9% Saline Solution on Mortality in Critically Ill PatientsThe BaSICS Randomized Clinical Trial – JAMA

Effect of Slower vs Faster Intravenous Fluid Bolus Rates on Mortality in Critically Ill Patients: The BaSICS Randomized Clinical Trial – JAMA

The ongoing saga of normal saline versus balanced fluids – First10EM

Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults – New England Journal of Medicine (link to abstract – $ for full-text)

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children – Cochrane Library

 


Brief Review | Monitoring cerebral oxygenation in acute brain-injured patients.

11 Jul, 2022 | 11:51h | UTC

Monitoring cerebral oxygenation in acute brain-injured patients – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


AHA Scientific Statement | Escalating and de-escalating temporary mechanical circulatory support in cardiogenic shock.

8 Jul, 2022 | 12:05h | UTC

Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock: A Scientific Statement From the American Heart Association – Circulation

Top Things to Know: Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock– American Heart Association

Commentary: Guiding Cardiogenic Shock Management: Filling in the (Wide) Data Gaps – American Heart Association

 


RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.

8 Jul, 2022 | 11:59h | UTC

Neutralizing COVID-19 Convalescent Plasma in Adults Hospitalized with COVID-19: A Blinded Randomized Placebo-Controlled Trial – CHEST

Commentary: Study shows convalescent plasma doesn’t benefit severely ill patients hospitalized with COVID-19 – Vanderbilt University Medical Center

 


Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.

8 Jul, 2022 | 12:02h | UTC

Oral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence

 


Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.

7 Jul, 2022 | 12:57h | UTC

Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients in general care in the Veterans Health Administration 2013-19: multicenter, retrospective cohort study – The BMJ

News Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 

Commentary on Twitter

 


Coagulation and transfusion updates from 2021.

7 Jul, 2022 | 12:36h | UTC

Coagulation and Transfusion Updates from 2021 – Journal of Cardiothoracic and Vascular Anesthesia

 


Perspective | The future of intensive care: delirium should no longer be an issue.

7 Jul, 2022 | 12:28h | UTC

The future of intensive care: delirium should no longer be an issue – Critical Care

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by/4.0/ license

 


RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.

6 Jul, 2022 | 11:51h | UTC

High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial – JAMA Internal Medicine

 

Commentary on Twitter


M-A | Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital.

5 Jul, 2022 | 12:19h | UTC

Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis – The BMJ


EM Cases | The 7 Ts of massive hemorrhage protocols.

5 Jul, 2022 | 11:35h | UTC

EM Cases: The 7 Ts of Massive Hemorrhage Protocols – emDocs


Guideline Synopsis | Evaluation and diagnosis of chest pain.

4 Jul, 2022 | 12:49h | UTC

Evaluation and Diagnosis of Chest Pain – JAMA (free for a limited period)

Original Guideline:

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines – Journal of the American College of Cardiology

News Release: First-Ever Guideline Focused Solely on Chest Pain Evaluation, Diagnosis Released

Guideline Hub: Guideline for the Evaluation and Diagnosis of Chest Pain

Key Points: 2021 AHA/ACC Chest Pain Guideline – American College of Cardiology

Commentary: New Chest Pain Guidelines Out at Last: Most Tests Have a Role – TCTMD


Brief Review | Ventilator-associated pneumonia.

4 Jul, 2022 | 12:15h | UTC

Ventilator-associated pneumonia – Intensive Care Medicine (if the link is paywalled, try this one in PMC)

 

Commentary on Twitter


How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care.

4 Jul, 2022 | 12:13h | UTC

How doctors manage conflicts with families of critically ill patients during conversations about end-of-life decisions in neonatal, pediatric, and adult intensive care – Intensive Care Medicine


RCT: A single immediate dose of intravenous tenecteplase is noninferior to alteplase for the treatment of patients with acute ischemic stroke.

1 Jul, 2022 | 11:44h | UTC

Intravenous tenecteplase compared with alteplase for acute ischaemic stroke in Canada (AcT): a pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

News Release: UCalgary researchers with the Calgary Stroke Program make another breakthrough in the treatment of stroke

 


Review: Nutrition management for critically ill adult patients requiring non-invasive ventilation.

1 Jul, 2022 | 10:42h | UTC

Nutrition Management for Critically Ill Adult Patients Requiring Non-Invasive Ventilation: A Scoping Review – Nutrients

 


Brief Review: Point-of-care ultrasound for critically-ill patients.

1 Jul, 2022 | 10:41h | UTC

Point-of-care ultrasound for critically-ill patients: A mini-review of key diagnostic features and protocols – World Journal of Critical Care Medicine

 


RCT: Effects of early Empagliflozin initiation on diuresis and kidney function in patients with acute decompensated heart failure.

30 Jun, 2022 | 11:24h | UTC

Effects of Early Empagliflozin Initiation on Diuresis and Kidney Function in Patients With Acute Decompensated Heart Failure (EMPAG-HF) – Circulation

 


Consensus Guidelines: Management of hematoma after thyroid surgery.

30 Jun, 2022 | 11:06h | UTC

Management of haematoma after thyroid surgery: systematic review and multidisciplinary consensus guidelines from the Difficult Airway Society, the British Association of Endocrine and Thyroid Surgeons and the British Association of Otorhinolaryngology, Head and Neck Surgery – Anaesthesia

 


Expert consensus: Diaphragm ultrasonography in the critically ill.

30 Jun, 2022 | 11:04h | UTC

EXpert consensus On Diaphragm UltraSonography in the critically ill (EXODUS): a Delphi consensus statement on the measurement of diaphragm ultrasound-derived parameters in a critical care setting – Critical Care

 


RCT: Prothrombin complex concentrate vs. plasma for post–cardiopulmonary bypass coagulopathy and bleeding.

30 Jun, 2022 | 10:50h | UTC

Prothrombin Complex Concentrate vs Plasma for Post–Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

https://twitter.com/JAMASurgery/status/1542176079728738305

 


Brief Review: Update on prevention of intra-vascular accesses complications.

30 Jun, 2022 | 10:38h | UTC

Update on prevention of intra-vascular accesses complications – Intensive Care Medicine (if the link is paywalled, try this one)

 

Commentary on Twitter

 


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