Critical Care & Emergencies (all articles)
M-A of RCT | Combination of ulinastatin and somatostatin evaluated in acute pancreatitis.
31 Oct, 2022 | 13:44h | UTC
RCT | Early active mobilization during mechanical ventilation in the ICU did not improve outcomes and increased adverse events.
28 Oct, 2022 | 13:28h | UTCEarly Active Mobilization during Mechanical Ventilation in the ICU – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/NEJM/status/1585246120963604481
RCT | Haloperidol for the treatment of delirium in ICU patients did not significantly improve outcomes.
28 Oct, 2022 | 13:29h | UTCHaloperidol for the Treatment of Delirium in ICU Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
In this randomized trial, treatment with haloperidol did not increase the number of days alive and out of the hospital among ICU patients with delirium. #LIVES2022 https://t.co/SCRUg3ff9X pic.twitter.com/0dInueHE76
— NEJM (@NEJM) October 26, 2022
RCT | Spontaneous-breathing trials performed with pressure-support ventilation are no better than trials using a T-piece.
28 Oct, 2022 | 13:25h | UTCSpontaneous-Breathing Trials with Pressure-Support Ventilation or a T-Piece – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
Among patients with a high risk of reintubation, spontaneous-breathing trials performed with pressure-support ventilation did not result in significantly fewer ventilator-free days at day 28 than T-piece trials. #LIVES2022 https://t.co/kqSDe3X89v pic.twitter.com/dCcPxdCWmJ
— NEJM (@NEJM) October 26, 2022
RCT | Selective decontamination of the GI tract did not significantly reduce mortality in ICU patients on mechanical ventilation.
27 Oct, 2022 | 12:40h | UTCEffect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
See also: Visual Abstract
Related study: Association Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
M-A | Selective decontamination of the GI tract may reduce in-hospital mortality in ICU patients receiving mechanical ventilation.
27 Oct, 2022 | 12:39h | UTCAssociation Between Selective Decontamination of the Digestive Tract and In-Hospital Mortality in Intensive Care Unit Patients Receiving Mechanical Ventilation: A Systematic Review and Meta-analysis – JAMA (free for a limited period)
Related Study: Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality in Critically Ill Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial – JAMA (free for a limited period)
RCT | A lower oxygen saturation target did not improve outcomes after out-of-hospital cardiac arrest.
27 Oct, 2022 | 12:38h | UTCEffect of Lower vs Higher Oxygen Saturation Targets on Survival to Hospital Discharge Among Patients Resuscitated After Out-of-Hospital Cardiac Arrest: The EXACT Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Early Oxygen Supplementation After Resuscitation From Cardiac Arrest – JAMA (free for a limited period)
Related:
Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)
Retrospective Cohort Study | Association of ECMO with new mental health diagnoses in adult survivors of critical illness.
27 Oct, 2022 | 12:37h | UTCAssociation of Extracorporeal Membrane Oxygenation With New Mental Health Diagnoses in Adult Survivors of Critical Illness – JAMA (free for a limited period)
Editorial: Mental Health Outcomes Following Extracorporeal Membrane Oxygenation in Survivors of Critical Illness – JAMA (free for a limited period)
News Release: ECMO survivors have higher rate of new mental health diagnoses than other ICU survivors – Ottawa Hospital
Commentary from the author on Twitter (thread – click for more)
? Long-term outcomes after #ECMO are lacking in the literature.
A brief thread on our new paper in @JAMA_current, looking at mental health outcomes in survivors after ECMO (OPEN ACCESS).
Thrilled to have presented the results live @ESICM #LIVES2022 https://t.co/xaqKxCky67 pic.twitter.com/4zUomfNE7K
— Shannon Fernando (@shanfernands) October 26, 2022
Cohort Study | Racial and ethnic differences in bystander CPR for witnessed cardiac arrest.
27 Oct, 2022 | 12:35h | UTCCommentary: Blacks, Hispanics Less Likely Than Whites to Receive Bystander CPR – HealthDay
Study commentary | From the management of altitude sickness to congestion in acute HF: a new season for acetazolamide?
27 Oct, 2022 | 12:27h | UTCFrom the management of altitude sickness to treatment of congestion in acute heart failure: a new season for acetazolamide? – European Heart Journal (free for a limited period)
Original study: RCT | Acetazolamide resulted in faster decongestion in patients with acute decompensated heart failure with volume overload.
The bleeding cervical cancer patient: systematic approach and management.
26 Oct, 2022 | 14:30h | UTCThe Bleeding Cervical Cancer Patient: Systematic Approach and Management – emDocs
New horizons in Type 2 myocardial infarction: pathogenesis, assessment and management of an emerging geriatric disease.
26 Oct, 2022 | 14:27h | UTC
RCT | In critically ill patients receiving MV, there was no difference in outcomes between different O2 saturation targets.
25 Oct, 2022 | 13:23h | UTCOxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation – New England Journal of Medicine (link to abstract – $ for full-text)
Related:
Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
In this trial involving patients receiving mechanical ventilation, randomly assigned low, intermediate, or high oxygenation targets did not alter the number of ventilator-free days. @CritCareReviews https://t.co/UUxrEPRxs6 pic.twitter.com/ueUSX8ZmHG
— NEJM (@NEJM) October 24, 2022
Diaphragmatic function in cardiovascular disease: JACC review topic of the week.
25 Oct, 2022 | 13:22h | UTC
Post-trial follow-up | IV calcium does not improve long-term outcomes in patients with out-of-hospital cardiac arrest.
25 Oct, 2022 | 13:17h | UTCOriginal Study: RCT: Intravenous or intraosseous calcium does not improve the return of spontaneous circulation in adults with out-of-hospital cardiac arrest.
Commentary on Twitter
From the latest issue of @ResusJournal Effect of calcium vs. placebo on long-term outcomes in patients with out-of-hospital cardiac arrest https://t.co/fSCr9DebS7 pic.twitter.com/rRw28GwP5Q
— Emergency Medicine (@ELS_Emerg_Med) September 2, 2022
Systematic Review | Point-of-care ultrasound in dyspnea, nontraumatic hypotension, and shock.
25 Oct, 2022 | 13:16h | UTC
Brief Review | Management of oliguria.
21 Oct, 2022 | 13:04h | UTCManagement of oliguria – Intensive Care Medicine (if the link is paywalled, try this one)
Commentary on Twitter
Oliguria relatively frequent in #ICU & perioperative setting, but most episodes not followed by #AKI:
➡️ physiological vs pathological
➡️ impact
➡️ management
Even if clinically important, interpret isolated oliguria with caution, considering context.
?️ https://t.co/xVs2Wa3mgB pic.twitter.com/4pX4UcHY1R— Intensive Care Medicine (@yourICM) October 21, 2022
Consensus Paper | Advanced bleeding control in combat casualty care.
21 Oct, 2022 | 12:59h | UTC
Clinical practice update for management of acute kidney injury associated with cardiac surgery.
20 Oct, 2022 | 12:31h | UTCSociety of Cardiovascular Anesthesiologists Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery – Anesthesia & Analgesia (free for a limited period)
Commentary on Twitter
The @scahq Clinical Practice Update for Management of Acute Kidney Injury Associated With Cardiac Surgery https://t.co/miFP5MkbnL @iars360
Potential renoprotective benefit:
❤️Goal-directed oxygen delivery on CPB
❤️KDIGO
❤️The use of vasopressin in vasoplegic shock pic.twitter.com/S9O2RtIhIr— Anesthesia&Analgesia (@IARS_Journals) October 13, 2022
Review | Update on the management of upper gastrointestinal bleeding.
20 Oct, 2022 | 12:29h | UTCUpdate on the management of upper gastrointestinal bleeding – BMJ Medicine
Cohort Study | Intravenous potassium and magnesium linked to spontaneous conversion of atrial fibrillation in the ED.
20 Oct, 2022 | 12:27h | UTC
Commentary on Twitter
IV potassium and magnesium was associated with higher rates of conversion in atrial fibrillation but not flutter during patients’ emergency department stays. https://t.co/p3nQK8zNMs
— JAMA Network Open (@JAMANetworkOpen) October 19, 2022
Pneumonia update for emergency clinicians.
19 Oct, 2022 | 14:19h | UTCPneumonia Update for Emergency Clinicians – Current Emergency and Hospital Medicine Reports
M-A | Nasal protection strategy reduces the incidence of nasal pressure injuries during nasotracheal intubation.
19 Oct, 2022 | 14:13h | UTC
Review | Optimizing PO2 during peripheral veno-arterial ECMO.
19 Oct, 2022 | 14:10h | UTCOptimizing PO2 during peripheral veno-arterial ECMO: a narrative review – Critical Care
Guideline | Diagnosis and management of febrile neutropenia in patients with cancer.
18 Oct, 2022 | 12:52h | UTCRelated: