M-A | Evaluation of direct oral anticoagulant reversal agents in intracranial hemorrhage.

Evaluation of Direct Oral Anticoagulant Reversal Agents in Intracranial Hemorrhage: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary on Twitter

Meta-analysis finds mostly successful DOAC reversal with 4F-PCC (77%), andexanet alfa (AA)(75%), and idarucizumab (82%) in patients with ICH. 4F-PCC and AA had comparable success in factor Xa inhibitor reversal, mortality, and thromboembolic outcomes. #OA https://t.co/aieJd9h5jo

— JAMA Network Open (@JAMANetworkOpen) November 4, 2022