Critical Care & Emergencies (all articles)
Guideline: Antiarrhythmic drugs–clinical use and clinical decision making
16 Feb, 2018 | 02:31h | UTCGuideline: Antiarrhythmic drugs–clinical use and clinical decision making: a consensus document from EHRA, ESC, HRS, APHRS and ISCP (free)
Source: Antiarrhythmics: multinational consensus recommendations – Univadis (free registration required)
Guideline: The Open Abdomen in Trauma and Non-Trauma Patients
16 Feb, 2018 | 02:28h | UTC
Guideline: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy
16 Feb, 2018 | 02:17h | UTCCommentary: New Guidelines for Treating Checkpoint Inhibitor Toxicities – Medscape (free registration required)
Relate guideline: Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free) AND Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Infographic: ATLS Trauma Update 2018
16 Feb, 2018 | 01:29h | UTCInfographic: ATLS Trauma Update 2018 (free) (via @CritCareReviews)
Uncertain benefits of BNP blood tests to monitor heart failure treatment
16 Feb, 2018 | 01:08h | UTCUncertain benefits of BNP blood tests to monitor heart failure treatment – NIHR Signal (free)
Perspective: Catheter-Directed Management in Acute Pulmonary Embolism
16 Feb, 2018 | 00:59h | UTC
Review: ED Approach to Agitation
15 Feb, 2018 | 10:44h | UTCemDocs Cases: ED Approach to Agitation – emDocs (free)
Meta-Analysis: Prognostic Accuracy of qSOFA and SIRS criteria for Mortality in Patients With Suspected Infection
9 Feb, 2018 | 12:42h | UTCPrognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: For mortality prediction, qSOFA has poor sensitivity, moderate specificity, review finds – ACP Hospitalist (free) AND Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection – 2 Minute Medicine (free)
Review: The Management of Multi-vessel disease (MVD) in STEMI
9 Feb, 2018 | 12:35h | UTC
Editorial: Nutritional Management During Noninvasive Ventilation
9 Feb, 2018 | 12:13h | UTC
Hydroxyethyl-starch Solutions (HES) Should no Longer be Used
9 Feb, 2018 | 11:47h | UTCPress release: Hydroxyethyl-starch solutions for infusion to be suspended (free)
Source: EMA calls for hydroxyethyl starch solutions to be taken off market – The BMJ News ($)
Review: Computed Tomographic Coronary Angiography in Patients with Possible Angina
9 Feb, 2018 | 11:46h | UTCHeartbeat: Computed tomographic coronary angiography in patients with possible angina – Heart (free)
Guideline: Diagnosis and Treatment of Catheter-Related Bloodstream infection
9 Feb, 2018 | 11:45h | UTCDiagnosis and treatment of catheter-related bloodstream infection: Clinical guidelines of the Spanish Society of Infectious Diseases and Clinical Microbiology and (SEIMC) and the Spanish Society of Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) (free PDF)
Meta-Analysis: Stress Ulcer Prophylaxis in Intensive Care Unit Patients Receiving Enteral Nutrition
9 Feb, 2018 | 11:42h | UTC
An Evidence-Based Approach to Pressors in Shock: Part I
9 Feb, 2018 | 11:39h | UTCAn Evidence-Based Approach to Pressors in Shock: Part I – emDocs (free)
Review: New Developments in Hepatorenal Syndrome
9 Feb, 2018 | 11:40h | UTCNew Developments in Hepatorenal Syndrome – Clinical Gastroenterology and Hepatology (free)
Early use of tranexamic acid reduces bleeding more effectively
5 Feb, 2018 | 16:51h | UTCEarly use of tranexamic acid reduces bleeding more effectively – NIHR Signal (free)
Original article: Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free) AND Invited Commentary: Tranexamic acid: is it about time? (free)
“It is now clearer that every 15-minute delay after the first hour can reduce survival by about 10%”.
Guideline: Gastrointestinal Complications in Adult Cancer Patients
5 Feb, 2018 | 16:53h | UTCGuideline: Diagnosis and management of gastrointestinal complications in adult cancer patients – German Society of Hematology and Medical Oncology (free)
Intravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis
5 Feb, 2018 | 16:50h | UTCIntravenous antibiotics, administered over 3 hours, are linked to lower death rates in sepsis – NIHR Signal (free)
Original article: Prolonged versus short-term intravenous infusion of antipseudomonal β-lactams for patients with sepsis: a systematic review and meta-analysis of randomised trials – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Research: Prevalence of Pulmonary Embolism in Patients With Syncope
5 Feb, 2018 | 16:46h | UTCPrevalence of Pulmonary Embolism in Patients With Syncope – JAMA Internal Medicine (free for a period)
Author Interview: Prevalence of Pulmonary Embolism in Patients With Syncope (free)
Commentaries: Prevalence of PE Low for Patients Presenting to ER With Syncope – Physician’s Weekly (free) AND Study Finds Pulmonary Embolus Rarely the Cause of Syncope – MedicalResearch.com (free)
Reviews: CAR T-Cell Therapy Toxicities and Side Effects
5 Feb, 2018 | 16:13h | UTCCAR T-Cell Therapy – What do you need to know for the ED? – emDocs (free)
Related reviews: Toxicities of chimeric antigen receptor T cells: recognition and management – Blood (free) AND Toxicity and management in CAR T-cell therapy – Molecular Therapy Oncolytics (free) AND New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Recommendations on the Use of Ultrasound Guidance for Adult Thoracentesis
4 Feb, 2018 | 18:27h | UTC
Blood Test Reduces Mortality and Shortens Antibiotic use Among Adults with Chest Infection
4 Feb, 2018 | 17:17h | UTCBlood test reduces mortality and shortens antibiotic use among adults with chest infection – NIHR Signal (free)
Original article: Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis – The Lancet (free)
Review: Hospitalisation in Patients With Heart Failure With Preserved Ejection Fraction
4 Feb, 2018 | 16:48h | UTC
Meta-Analysis: Fluid Balance and Outcomes in Critically Ill Children
30 Jan, 2018 | 19:57h | UTCAssociation Between Fluid Balance and Outcomes in Critically Ill Children: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a period)
Commentaries: Fluid Overload Boosts Mortality in Critically Ill Children – Medscape (free registration required)