Critical Care & Emergencies (all articles)
ESC/EACTS Guidelines on Myocardial Revascularization
31 Aug, 2018 | 03:09h | UTC2018 ESC/EACTS Guidelines on myocardial revascularization – European Heart Journal (free) (via @escardio see Tweet with Key Infographics)
Randomized Trial: Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery
31 Aug, 2018 | 03:05h | UTCSix-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery – New England Journal of Medicine (free for a limited period)
“In moderate-to-high-risk patients undergoing cardiac surgery, six-month outcomes show that a restrictive red-cell transfusion strategy is noninferior to a liberal strategy” (via @NEJM see Tweet with Visual Abstract)
Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome
31 Aug, 2018 | 02:49h | UTCCommentaries: Diagnosing myocardial infarction: a highly sensitive issue – The Lancet (free) AND Hs-TnI in Suspected ACS: High-STEACS Trial – American College of Cardiology (free) AND Is High Sensitivity Troponin Too Sensitive? – NEJM Journal Watch (free)
“Introduction of a high-sensitivity cardiac troponin I assay reclassified 1 in 6 patients with previously undetected myocardial necrosis, but did not lead to improved clinical outcomes in this large randomised trial” (via @chapdoc1 see Tweet)
“Very important study. What’s weird is that the “better” (more sensitive) troponin assays get, the less helpful the test becomes at the bedside. Look for a coming tsunami of iatrogenesis from overzealous evaluation of troponin bumps.” (via @drjohnm see Tweet)
Guideline: Management of Hypertensive Emergencies
31 Aug, 2018 | 02:45h | UTCESC Council on hypertension position document on the management of hypertensive emergencies – European Heart Journal – Cardiovascular Pharmacotherapy (free) (@Abraham_RMI)
“Patients that lack acute hypertension-mediated end organ damage to the heart, retina, brain, kidneys, or large arteries do not have a hypertensive emergency and can be treated with oral BP-lowering agents and usually discharged after a brief period of observation.”
Clinical Decisions: Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
31 Aug, 2018 | 02:39h | UTC
Randomized Trial: Early vs. Standard Care Invasive Examination and Treatment of Patients with NSTE-ACS
31 Aug, 2018 | 02:29h | UTCEditorial: Timing of Intervention in Non ST Elevation Acute Coronary Syndromes: And the VERDICT is? (free PDF)
Commentaries: VERDICT: Very Early Invasive Coronary Angiography vs. Standard Care in NSTE-ACS Patients- American College of Cardiology (free) AND ESC: Early Invasive Strategy in NSTEMI Does Not Improve Outcomes – MedPage Today (free registration required) AND VERDICT: Very Early Invasive Angiography No Help Overall for NSTE ACS – TCTMD (free)
Randomized Trial: One-Year Outcomes after PCI Strategies in Cardiogenic Shock
31 Aug, 2018 | 02:05h | UTCOne-Year Outcomes after PCI Strategies in Cardiogenic Shock – New England Journal of Medicine (free for a limited period)
Commentaries: Less Is Still More in Patients with Acute Myocardial Infarction and Cardiogenic Shock – NEJM Journal Watch (free for a limited period) AND 1-year outcomes still support culprit-only PCI for cardiogenic shock – Cardiovascular Business (free) CULPRIT-SHOCK: 1-Year Results Continue to Support Culprit-Only PCI for Shock Patients – TCTMD (free)
Review: Acute Clinical Care for Transgender Patients
31 Aug, 2018 | 01:59h | UTCAcute Clinical Care for Transgender Patients – JAMA Internal Medicine (free for a limited period) (via @CarlosdelRio7)
Review: Treatment of Invasive Candidiasis
31 Aug, 2018 | 01:47h | UTCTreatment of Invasive Candidiasis: A Narrative Review – Journal of Fungi (free)
Source: Hospital Medicine Virtual Journal Club
Review: Imaging in Trauma in Limited-Resource Settings
31 Aug, 2018 | 01:42h | UTCSource: Critical Care Reviews Newsletter
Review: Difficult Tracheal Intubation in Critically Ill
23 Aug, 2018 | 23:48h | UTCDifficult tracheal intubation in critically ill – Journal of Intensive Care (free)
Extended Antibiotic Infusions Could Save Lives: Here’s How to Do It
23 Aug, 2018 | 23:40h | UTCExtended antibiotic infusions could save lives: Here’s how to do it – PulmCCM (free)
Related Research: Mortality lower with prolonged vs. short-term IV infusion of antipseudomonal beta-lactams (free)
“The simplest (and cheapest) technique is simply to reduce the time between doses.”
Study: Seven Days of Antibiotics Were as Good as 14 for Gram-Negative Bacteremia
23 Aug, 2018 | 23:39h | UTCSeven days of antibiotics were as good as 14 for gram-negative bacteremia – PulmCCM (free)
Related Commentary: Seven-day antibiotic course delivers similar outcomes to 14-days for Gram-negative bacteraemia – European Society of Clinical Microbiology and Infectious Diseases, via EurekAlert (free)
“It’s important to note that source control was believed to be achieved in all enrolled patients. If source control cannot be achieved (e.g., an abscess, or an infected heart valve or indwelling catheter that cannot safely be removed), prolonged antibiotic courses are often advisable.”
Consensus: Management of Antithrombotic Therapy in AF Patients Presenting with ACS and/or Undergoing PCI
23 Aug, 2018 | 23:27h | UTCJoint Consensus Document: Management of antithrombotic therapy in AF patients presenting with ACS and/or undergoing PCI – European Heart Journal (free)
Guideline: Acute Kidney Injury
23 Aug, 2018 | 23:24h | UTCThe Japanese Clinical Practice Guideline for acute kidney injury 2016 – Journal of Intensive Care (free)
WSES Guideline: Colon and Rectal Cancer Emergencies
23 Aug, 2018 | 23:25h | UTC
Meta-Analysis: Effect of Procalcitonin-Guided Antibiotic Treatment on Clinical Outcomes in ICU patients
23 Aug, 2018 | 23:21h | UTCCommentary: Procalcitonin guidance linked to improved sepsis survival – Univadis (free registration required)
Cohort Study: Assessment of the Safety of Discharging Select Patients Directly Home From the ICU
23 Aug, 2018 | 23:01h | UTCAssessment of the Safety of Discharging Select Patients Directly Home From the Intensive Care Unit: A Multicenter Population-Based Cohort Study – JAMA Internal Medicine (free for a limited period)
Invited Commentary: The Complexity and Challenges of Intensive Care Unit Admissions and Discharges: Similarities With All Hospitalized Patients – JAMA Internal Medicine (free for a limited period)
Study: Clinical Chemistry Score to Identify Patients at Low or High Risk for Myocardial Infarction or Death
23 Aug, 2018 | 22:36h | UTCCommentaries: Simple score to diagnose heart attacks is safer, faster than current methods – McMaster University (free) AND Clinical Chemistry Score Helps Rule Out Diagnosis of Heart Attack – MedicalResearch.com (free)
Meta-Analysis: Corticosteroids in Sepsis
23 Aug, 2018 | 22:32h | UTCCorticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis – Critical Care Medicine (free)
Related: Corticosteroid therapy for sepsis: a clinical practice guideline – The BMJ (free)
Review: Intravenous Fluid Therapy in Critically ill Adults
23 Aug, 2018 | 22:30h | UTCIntravenous fluid therapy in critically ill adults – Nature Reviews Nephrology (free for a limited period) (via @CritCareReviews)
Review: Airway and Ventilation Management During CPR and After Successful Resuscitation
23 Aug, 2018 | 22:27h | UTC
Guideline: Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in the ICU
17 Aug, 2018 | 02:32h | UTCClinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU – Critical Care Medicine (free) (via @Abraham_RMI)
Meta-Analysis: Absolute Risk and Predictors of the Growth of Acute Spontaneous Intracerebral Hemorrhage
17 Aug, 2018 | 02:25h | UTCCommentary: Brain scan checklist set to boost care for stroke survivors – University of Edinburgh, via EurekAlert (free)
Study: Trends in Use of Daily Chest Radiographs Among Patients Receiving Mechanical Ventilation
17 Aug, 2018 | 02:23h | UTCCommentaries: Daily Chest X-Rays Still Overused in Mechanically Ventilated Patients – MedicalResearch.com (free) AND Routine daily CXRs for ventilated patients: de-adoption is lagging – Univadis (free registration required) AND Chest x-rays overused on ventilation patients despite ACR guideline – HealthImaging (free)