Critical Care & Emergencies (all articles)
Consensus Statements: Antibiotic Therapy in Acute Pancreatitis
16 May, 2019 | 05:47h | UTC
Systematic Review: Levosimendan for Decompensated Congestive Heart Failure
16 May, 2019 | 05:38h | UTC“In patients with dilated cardiomyopathy and ejection fraction < 30% (heart failure post-intervention or not), levosimendan does not reduce the risk of death.”
Consensus Statement on the Management of Arrhythmogenic Cardiomyopathy
14 May, 2019 | 06:07h | UTCCommentary: HRS releases consensus statement on arrhythmogenic cardiomyopathy: 5 things to know – Cardiovascular Business (free)
Obesity in the Critically Ill: A Narrative Review
14 May, 2019 | 06:05h | UTCObesity in the critically ill: a narrative review – Intensive Care Medicine (free)
Related Reviews: The Crashing Obese Patient – West Journal of Emergency Medicine (free) AND ARDS in Obese Patients: Specificities and Management – Critical Care (free)
Source: Critical Care Reviews Newsletter
Opinion Piece Suggests Lack of Scientific Rigor in Study Extending the Time Window to IV TPA
13 May, 2019 | 01:21h | UTC“The Case of the Magician’s Sleight” – EMNerd (free)
See also: EXTEND Alteplase Shenanigans! – Emergency Medicine Literature of Note (free)
Original Study: Randomized Trial: Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke (link to abstract and commentary)
Related Cochrane Review: Thrombolysis for acute ischaemic stroke (free)
Related Review: Thrombolytics for stroke: The evidence – First10Em (free)
Related Commentary on Twitter
Using statistical magic to extend the time window for IV tPA by @EMNerd_ https://t.co/s0zgEdbs4x pic.twitter.com/ReHsFqTWWC
— the EMCrit Crew (@emcrit) May 10, 2019
Turkish Consensus Paper on The Rational Use of Cardiac Troponins in Daily Practice
13 May, 2019 | 01:11h | UTC
Management of Blood Pressure After Acute Ischemic Stroke
12 May, 2019 | 21:39h | UTC
Editorial: The Global Challenge of Candida Auris in the Intensive Care Unit
11 May, 2019 | 15:49h | UTCThe global challenge of Candida auris in the intensive care unit – Critical Care (free)
Related: Candida Auris – “A Mysterious Infection, Spanning the Globe in a Climate of Secrecy” (free commentaries, guidelines and reviews)
Source: Critical Care Reviews Newsletter
Meta-analysis: Vasopressin in Septic Shock
10 May, 2019 | 05:07h | UTC“Vasopressin therapy in septic shock had no effect on 28-day mortality”
Randomized Trial: Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke
9 May, 2019 | 08:13h | UTCThrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: IV Thrombolysis Could Be Given Up to 9 Hours After Stroke Onset in Some – NEJM Journal Watch (free)
Related Randomized Trial: MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset (free study and commentaries)
Push-Dose Vasopressors: An Update for 2019
8 May, 2019 | 07:09h | UTCPush-Dose Vasopressors: An Update for 2019 – emDocs (free)
Related: A Comparative Study of Bolus Norepinephrine, Phenylephrine, and Ephedrine for the Treatment of Maternal Hypotension in Parturients with Preeclampsia During Cesarean Delivery Under Spinal Anesthesia – Medical Science Monitor (free) AND Bolus-Dose Vasopressors in the Emergency Department: First, Do No Harm; Second, More Evidence Is Needed – Annals of Emergency Medicine (free PDF)
AAST Critical Care Committee Clinical Consensus: ECMO
8 May, 2019 | 02:08h | UTCAAST Critical Care Committee clinical consensus: ECMO – Trauma Surgery & Acute Care Open (free)
Meta-Analysis: Early Initiation of Renal Replacement Therapy in Critically Ill Patients
7 May, 2019 | 01:14h | UTCRelated: Updates in Management and Timing of Dialysis in Acute Kidney Injury (free) AND Randomized Trial: Early vs. Delayed Dialysis in Acute Kidney Injury (free study and commentaries)
Review: Ventilation in Patients with Intra-abdominal Hypertension
6 May, 2019 | 22:28h | UTC
Randomized Trial: Early Norepinephrine Has Potential in Septic Shock
5 May, 2019 | 22:00h | UTCEarly Norepinephrine Has Potential in Septic Shock – Emergency Medicine News (free)
Original Study: Randomized Trial: Early Use of Norepinephrine in Septic Shock Resuscitation (link to abstract and commentary)
Related Commentary on Twitter
Don’t change your #sepsis protocols yet, says @First10EM, but #CENSER was a promising RCT showing early #norepinephrine improved some disease-oriented outcomes. Read this article #AHEADOFPRINT https://t.co/9D0L6wyx4t #FOAMed pic.twitter.com/y2vR09qDOV
— Emergency Medicine News (@EMNews) May 1, 2019
A Decade of Progress in Critical Care Echocardiography
1 May, 2019 | 07:16h | UTCA decade of progress in critical care echocardiography: a narrative review – Intensive Care Medicine (free)
Related Commentary on Twitter
Should all ICU physicians know basic CCE?
Narrative review by @AVBmir @Echotrainer et al on the progress of critical care echocardiograhy (CCE) during the last decade.
Available at https://t.co/K9N4yGXT3M@ClinMedJournals @Dr_Cit @ESICM @pbhjortrup pic.twitter.com/vSWe8Ml5hl— Intensive Care Medicine (@yourICM) April 25, 2019
Diagnostic and Therapeutic Approach to Infectious Diseases in Solid Organ Transplant Recipients
1 May, 2019 | 07:22h | UTCRelated: 10 Tips for Intensive Care Management of Transplanted Patients (free articles) AND Special Issue: Infections in Solid Organ Transplantation Guidelines (free articles)
Source: Critical Care Reviews Newsletter
Guideline: Unscheduled Procedural Sedation
30 Apr, 2019 | 02:47h | UTC
Strategies for Optimal Calorie Administration in Critically Ill Patients
30 Apr, 2019 | 02:22h | UTCStrategies for optimal calorie administration in critically ill patients – Journal of Intensive Care (free)
Related Guidelines: ASPEN/SCCM Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient (free) AND ESPEN guideline on clinical nutrition in the intensive care unit – Clinical Nutrition (free)
Review: Acute Management of Hyperkalemia
28 Apr, 2019 | 13:33h | UTCAcute Management of Hyperkalemia – Current Heart Failure Reports (free)
Related: Management of Hyperkalemia in the Acutely Ill Patient (free reviews)
Review: Hepatorenal Syndrome
24 Apr, 2019 | 06:21h | UTCHepatorenal Syndrome – Clinical Journal of American Society of Nephrology (free)
Related: Epidemiology, Pathophysiology, and Management of Hepatorenal Syndrome (free guidelines and reviews)
Review: Management of Brainstem Hemorrhages
24 Apr, 2019 | 06:10h | UTCManagement of brainstem haemorrhages – Swiss Medical Weekly (free)
ICU–acquired Weakness: Unanswered Questions and Targets for Future Research
24 Apr, 2019 | 06:05h | UTC
Perspective: Why Most Diagnostic Procedures Aren’t Beneficial
23 Apr, 2019 | 01:45h | UTCWhy most diagnostic procedures aren’t beneficial – PulmCrit (free)
“when strict evidence-based medicine is applied to procedures, they are often less impressive”.
Study: Most Sepsis-associated Deaths are Related to Severe Chronic Comorbidities and are Unlikely to be Preventable Through Better Hospital-based Care
22 Apr, 2019 | 01:49h | UTCCommentaries: A Closer Look at Sepsis-Associated Mortality – JAMA Network Open (free) AND Sepsis a leading cause of death in US hospitals but many deaths may not be preventable – Brigham and Women’s Hospital (free) AND More than 90% of sepsis deaths may be unpreventable, study concludes – PulmCCM (free)