Critical Care & Emergencies (all articles)
Cricoid Pressure not Helpful During Endotracheal Intubation in Large Trial
25 Feb, 2019 | 00:58h | UTCCricoid pressure no help during endotracheal intubation in large trial – PulmCCM (free)
Original Article: Randomized Trial: Cricoid Pressure vs. Sham Procedure in Elective Intubation (link to abstract)
Related Commentary: The Case of the Inferior Superiority – EMNerd (free)
Opinion – “Things We Do for No Reason: The Use of Thickened Liquids in Treating Hospitalized Adult Patients with Dysphagia”
22 Feb, 2019 | 01:21h | UTCSee Complete Series of Things We Do For No Reason (free articles)
Current Use of Vasopressors in Septic Shock
21 Feb, 2019 | 04:13h | UTCCurrent use of vasopressors in septic shock – Annals of Intensive Care (free)
The Difficult Airway Trolley: A Narrative Review and Practical Guide
21 Feb, 2019 | 04:10h | UTCRelated Guidelines: Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free)
“Despite several national guidelines on management of the anticipated and unanticipated difficult airway, with separate guidelines for pediatric, obstetric, and intensive care settings, only limited effort has been directed towards developing specific suggestions regarding the contents of a Difficult Airway Trolley”
Randomized Trial: Bag-Mask Ventilation vs. No-ventilation during Tracheal Intubation of Critically Ill Adults
20 Feb, 2019 | 03:11h | UTCBag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults – New England Journal of Medicine (free for a limited period)
Editorial: Preventing Dogma from Driving Practice (free for a limited period)
Commentaries: Is pure RSI a failed paradigm in critical illness? The primacy of pressure – PulmCrit (free) Higher O2 Sats With Manual Vent During Intubation of Critically Ill – Drugs.com (free) AND Helping patients breathe during dangerous procedure prevents complications – Vanderbilt University Medical Center (free)
Related Commentary on Twitter
Original Article: Bag-Mask Ventilation during Tracheal Intubation of Critically Ill Adults (PreVent) https://t.co/r3FFnXcQtt
Editorial: Preventing Dogma from Driving Practice https://t.co/nLGDAE0v2d #CCC48 pic.twitter.com/15IupOqCr3
— NEJM (@NEJM) February 19, 2019
Randomized Trial: Pneumatic Compression for DVT Prophylaxis in ICU Patients Receiving Pharmacologic Therapy
20 Feb, 2019 | 03:09h | UTCAdjunctive Intermittent Pneumatic Compression for Venous Thromboprophylaxis – New England Journal of Medicine (free for a limited period)
Review: Challenges in the Management of Septic Shock
20 Feb, 2019 | 03:08h | UTCChallenges in the management of septic shock: a narrative review – Intensive Care Medicine (free)
Note: if the link above is paywalled, try this one
Randomized Trial: Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels in Patients with Septic Shock
18 Feb, 2019 | 23:51h | UTCEffect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: How Best to Resuscitate Patients With Septic Shock? (free)
See also: Visual Abstract (free PDF)
Discussion Forum: ANDROMEDA-SHOCK (or, how to intepret HR 0.76, 95% CI 0.55-1.02, p=0.06) – Datamethods Discussion Forum (free)
Canadian Guidelines on the Acute Management of ST-Elevation Myocardial Infarction: Focused Update on Regionalization and Reperfusion
17 Feb, 2019 | 21:34h | UTCRelated Guideline: 2018 ESC/EACTS Guidelines on myocardial revascularization – European Heart Journal (free)
Systematic Review: Management of Acute Respiratory Failure Due to Community-Acquired Pneumonia
17 Feb, 2019 | 19:40h | UTC
Study: Decontamination of the Mouth or Digestive Tract Not Effective for Reducing Drug-resistant Bloodstream Infections in the ICU
16 Feb, 2019 | 20:20h | UTCOriginal Study: Randomized Trial: Decontamination Strategies and Bloodstream Infections with Antibiotic-Resistant Microorganisms in Ventilated Patients (link to abstract)
Randomized Trial: Early Use of Norepinephrine in Septic Shock Resuscitation
16 Feb, 2019 | 13:58h | UTCEarly Use of Norepinephrine in Septic Shock Resuscitation (CENSER) : A Randomized Trial – American Journal of Respiratory and Critical Care Medicine (link to abstract – $ for full-text)
See Commentary by Wellington ICU
“This is a promising result, and more and larger studies are needed to confirm the findings.” (from Wellington ICU)
Chinese Guidelines on the Management of Ascites and its Related Complications in Cirrhosis
16 Feb, 2019 | 13:49h | UTCNote: if the above link is not working, try this one
Related Guidelines: Evidence-based clinical practice guidelines for liver cirrhosis 2015 – Journal of Gastroenterology (free) AND Management of Adult Patients with Ascites Due to Cirrhosis: Update 2012 – American Association for the Study of Liver Diseases (free PDF) EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis (free) AND KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications – Clinical and Molecular Hepatology (free) AND Cirrhosis in Over 16s: Assessment and Management – National Institute for Health and Care Excellence (free)
Meta-Analysis: Fever Control in Critically Ill Adults
16 Feb, 2019 | 13:54h | UTCNote: if the above link is not working, try this one
“Our findings do not support the hypothesis that more active fever management increases survival compared with less active fever management overall or in patients with limited physiological reserves.”
Does This Patient Have a Severe Snake Envenomation?
14 Feb, 2019 | 01:48h | UTCDoes This Patient Have a Severe Snake Envenomation? The Rational Clinical Examination Systematic Review – JAMA Surgery (free for a limited period)
Related: Global Mapping of Vulnerability to Snakebite Envenoming (free study and commentaries) AND Why Are So Many People Still Dying from Snake Bites? (free) AND Snakebite finally makes a WHO list of top global health priorities (free) AND Snakebites Make The List Of ‘Neglected Tropical Diseases’ (free)
Meta-Analysis: Hypotensive Resuscitation in Patients with Traumatic Hemorrhagic Shock
14 Feb, 2019 | 01:45h | UTCCommentary: Permissive hypotensive resuscitation in patients with traumatic hemorrhagic shock – Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (free)
Severe Toxicity from Checkpoint Protein Inhibitors: What Intensive Care Physicians Need to Know?
13 Feb, 2019 | 02:02h | UTCRelated Review: New drugs, new toxicities: severe side effects of modern targeted and immunotherapy of cancer and their management – Critical Care (free)
Related Guidelines: Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline (free) AND Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group (free)
Randomized Trial: Intensive Blood Pressure Reduction Does Not Improve Outcomes in Patients with Acute Ischemic Stroke Treated with Thrombolytics
13 Feb, 2019 | 01:52h | UTCIntensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Intensive Blood Pressure Lowering With Intravenous Thrombectomy for Acute Ischemic Stroke Did Not Improve Functional Outcomes – Practical Neurology (free) AND Tighter BP Control No Better in Acute Stroke – MedPage Today (free registration required)
Randomized Trial: Intense IV Blood Sugar Control Doesn’t Improve Stroke Outcomes
11 Feb, 2019 | 00:15h | UTCCommentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)
Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)
“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)
The Aftermath of Acute Kidney Injury: A Narrative Review of Long-term Mortality and Renal Function
10 Feb, 2019 | 14:26h | UTC
Review: Epidemiology and Antimicrobial Resistance in Intensive Care Units
10 Feb, 2019 | 13:54h | UTC
Expert Panel Recommendations: Fluid Administration for Acute Circulatory Dysfunction Using Basic Monitoring
7 Feb, 2019 | 23:26h | UTCFluid administration for acute circulatory dysfunction using basic monitoring: narrative review and expert panel recommendations from an ESICM task force – Intensive Care Medicine (free for a limited period)
Note: if the above link is paywalled, try this one
Related Commentary on Twitter
Fluid administration for acute circulatory failure: go back to the basics, thanks to the expert panel recommendations from an ESICM task force!
Read the full text article for free at https://t.co/VPtl6cD0aN @Dr_Cit @ESICM @ClinMedJournals pic.twitter.com/pBoJiKHihT— Intens Care Med (@yourICM) February 1, 2019
Guideline: Best Practice Advice on Pre-hospital Emergency Anesthesia & Advanced Airway Management
7 Feb, 2019 | 23:20h | UTC
Podcast: Hyperkalemia Master Class
6 Feb, 2019 | 00:52h | UTC#137 Hyperkalemia Master Class with Joel Topf MD – The Curbsiders Internal Medicine Podcast (free)
International Consensus Guidelines for the Optimal Use of the Polymyxins
4 Feb, 2019 | 23:45h | UTCInternational Consensus Guidelines for the Optimal Use of the Polymyxins – Pharmacotherapy (free)
Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti‐infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).