Critical Care & Emergencies (all articles)
Esophageal Emergencies: WSES Guidelines
3 Jun, 2019 | 07:45h | UTCEsophageal emergencies: WSES guidelines – World Journal of Emergency Surgery (free)
State of the Art Review: Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic Syndrome
3 Jun, 2019 | 07:38h | UTCDiabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: review of acute decompensated diabetes in adult patients – The BMJ (free for a limited period)
Related Commentary on Twitter
Recommendations for acute management of diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome, the complications associated with these disorders, and methods for preventing recurrence #BMJEducation https://t.co/6CsGD5HLS0
— The BMJ (@bmj_latest) June 2, 2019
Guideline: Reversal of Direct Oral Anticoagulants
3 Jun, 2019 | 07:14h | UTCCommentary: Reversal of Direct Oral Anticoagulants – NEJM Journal Watch (free for a limited period)
The Serotonin Syndrome: From Molecular Mechanisms to Clinical Practice
29 May, 2019 | 10:47h | UTC
Meta-analysis: Comparative Efficacy of Vasoactive Medications in Patients with Septic Shock
29 May, 2019 | 10:43h | UTC
Step-up Approach for the Management of Pancreatic Necrosis
29 May, 2019 | 10:31h | UTCSource: Critical Care Reviews Newsletter
Commentary: Nebulized TXA for Hemoptysis
28 May, 2019 | 10:31h | UTCNebulized TXA for Hemoptysis (Wand 2018) – First10Em (free)
Original Article: Inhaled Tranexamic Acid for Hemoptysis Treatment: A Randomized Controlled Trial – Chest (link to abstract – $ for full-text)
Related Reviews: Approach to Hemoptysis in the Modern Era – Canadian Respiratory Journal (free) AND 2018 Korean Clinical Imaging Guideline for Hemoptysis – Korean Journal of Radiology (free) AND A systematic approach to the management of massive hemoptysis – Journal of Thoracic Disease (free) AND The Diagnosis and Treatment of Hemoptysis – Deutsches Ärzteblatt international (free)
See also: Evidence Review: Tranexamic Acid (TXA) for Everything that Bleeds? (free studies and commentaries)
Guidelines on the Management of Acute Respiratory Distress Syndrome
28 May, 2019 | 01:26h | UTCGuidelines on the management of acute respiratory distress syndrome – BMJ Open Respiratory Research (free)
Related Reviews: Acute Respiratory Distress Syndrome – Nature Reviews Disease Primer (free PDF) AND Acute Respiratory Distress Syndrome – European Respiratory Review (free)
Related Guidelines: The clinical practice guideline for the management of ARDS in Japan – Journal of Intensive Care (free) AND An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome (free)
Source: Critical Care Reviews Newsletter
Inpatient Management of Acute Severe Ulcerative Colitis
28 May, 2019 | 00:59h | UTCInpatient Management of Acute Severe Ulcerative Colitis – Journal of Hospital Medicine (free PDF via Unpaywall)
Source: Hospital Medicine Virtual Journal Club
[Abstract Only] Randomized Trial: Patients with COPD Exacerbation and Low Eosinophil Count May be Treated with Shorter Corticosteroid Treatment
24 May, 2019 | 05:19h | UTCEosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)
Commentary: 2 Minute Medicine Rewind May 20, 2019 (4th Summary)
See also: Video Summary – Medwire News (free audio)
Related Commentary on Twitter
Presenting now at #ATS2019 @atscommunity—Eosinophil-guided corticosteroid therapy in patients admitted to hospital with #COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial https://t.co/YqUlX54gc5 pic.twitter.com/Bw1n9Tuink
— The Lancet Respiratory Medicine (@LancetRespirMed) May 20, 2019
Management of Antiplatelet Therapy for Non-elective Invasive Procedures of Bleeding Complications
24 May, 2019 | 05:26h | UTC
Neutrophil-Lymphocyte Ratio (NLR): Free Upgrade to your WBC
24 May, 2019 | 05:14h | UTCNeutrophil-Lymphocyte Ratio (NLR): Free upgrade to your WBC – PulmCrit (free)
Review: Adjuvant Antithrombotic Therapy in ST-elevation Myocardial Infarction
23 May, 2019 | 12:54h | UTC
[Abstract Only] Meta-Analysis: Extending Thrombolysis to 4·5–9 h and Wake-up Stroke Using Perfusion Imaging
23 May, 2019 | 08:04h | UTCExtending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data – The Lancet (link to abstract – $ for full-text)
“Patients with ischemic stroke 4·5–9 h from stroke onset or wake-up stroke with salvageable brain tissue who were treated with alteplase achieved better functional outcomes than did patients given placebo. The rate of symptomatic intracerebral hemorrhage was higher with alteplase, but this increase did not negate the overall net benefit of thrombolysis.”
Related Commentary on Twitter
Presenting now at #ESOC2019 @ESOstroke—Extending #thrombolysis to 4·5–9 h and wake-up #stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data https://t.co/Ep0JDiGzoF pic.twitter.com/lHqiWc63ji
— The Lancet (@TheLancet) May 22, 2019
Current Concepts in Acute Liver Failure
22 May, 2019 | 06:00h | UTCCurrent concepts in acute liver failure – Annals of Hepatology (free)
Editorial: What’s New in Oxygen therapy?
22 May, 2019 | 05:57h | UTCWhat’s new in oxygen therapy? – Intensive Care Medicine (free)
Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Review: Oxygen Treatment in Intensive Care and Emergency Medicine (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
Source: Critical Care Reviews Newsletter
Perspective: Eight Things We Would Never do Regarding End-of-life Care in the ICU
22 May, 2019 | 05:53h | UTCEight things we would never do regarding end-of-life care in the ICU – Intensive Care Medicine (free)
Related: Limitation of Life-Sustaining Care in the Critically Ill: A Systematic Review of the Literature – Journal of Hospital Medicine (free PDF) AND Dying with Dignity in the Intensive Care Unit – New England Journal of Medicine (free) AND Palliative care in intensive care units: why, where, what, who, when, how – BMC Anesthesiology (free) AND Ten key points about ICU palliative care – Intensive Care Medicine (free) AND Guidelines for the withdrawal of life-sustaining measures – Intensive Care Medicine (free) AND End-of-life in the ICU: moving from ‘withdrawal of care’ to a palliative care, patient-centred approach – British Journal of Anaesthesia (free) AND New concepts in palliative care in the intensive care unit – Revista Brasileira de Terapia Intensiva (free) AND The Changing Role of Palliative Care in the ICU – Critical Care Medicine (free)
Source: Critical Care Reviews Newsletter
#ATS2019 – Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis
21 May, 2019 | 06:21h | UTCDerivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis – JAMA (free for a limited period)
Editorial: New Phenotypes for Sepsis: The Promise and Problem of Applying Machine Learning and Artificial Intelligence in Clinical Research (free for a limited period)
Commentary: Big data reveals hidden subtypes of sepsis – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – [Abstract Only] Randomized Trial: Early Sedation with Dexmedetomidine Not Helpful in Critically Ill Patients
21 May, 2019 | 06:19h | UTCEarly Sedation with Dexmedetomidine in Critically Ill Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Just Presented at the 2019 Meeting of the American Thoracic Society.
#ATS2019 – Randomized Trial: Early Neuromuscular Blockade Do Not Benefit Patients with Acute Respiratory Distress Syndrome
21 May, 2019 | 06:18h | UTCEarly Neuromuscular Blockade in the Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Sedation and controlled paralysis do not improve survival of ICU patients with ARDS – University of Pittsburgh (free)
Just Presented at the 2019 Meeting of the American Thoracic Society.
Related Commentary on Twitter
This trial revisited research conducted about a decade ago that showed a survival benefit with early neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS). See the results of the new trial: https://t.co/lcLOUirsOM #ATS2019
— NEJM (@NEJM) May 19, 2019
SCAI Clinical Expert Consensus Statement on the Classification of Cardiogenic Shock
21 May, 2019 | 05:59h | UTCSCAI clinical expert consensus statement on the classification of cardiogenic shock – Catheterization Cardiovascular Interventions (free) (via @paomorejon)
Related: Cardiogenic shock: evolving definitions and future directions in management – openheart (free)
Commentaries: SCAI releases multi-society endorsed consensus on the classification stages of cardiogenic shock – Society for Cardiovascular Angiography and Interventions (free) AND SCAI Clinical Expert Consensus Statement on Cardiogenic Shock – American College of Cardiology (free)
“Endorsed by the American College of Cardiology (ACC), the American Heart Association (AHA), the Society of Critical Care Medicine (SCCM), and the Society of Thoracic Surgeons (STS) in April 2019”
[Abstract Only] Meta-Analysis: Vitamin C Does Not Improve Outcomes in Critically Ill Patients
20 May, 2019 | 22:26h | UTCThe Effect of Vitamin C on Clinical Outcome in Critically Ill Patients: A Systematic Review With Meta-Analysis of Randomized Controlled Trials – Critical Care Medicine (link to abstract – $ for full-text)
Review: New-onset Atrial Fibrillation in Adult Critically Ill Patients
19 May, 2019 | 22:27h | UTCNew-onset atrial fibrillation in adult critically ill patients: a scoping review – Intensive Care Medicine (free) (via @AndersPerner)
Clinical Review: Peripheral Muscular Ultrasound in the ICU
19 May, 2019 | 13:10h | UTCClinical review: peripheral muscular ultrasound in the ICU – Annals of Intensive Care (free)
Review: Spontaneous Coronary Artery Dissections and Associated Predisposing Factors
16 May, 2019 | 06:03h | UTCRelated AHA Guideline: Spontaneous Coronary Artery Dissection (free)
Related Review: Spontaneous Coronary Artery Dissection: An Often Unrecognized Cause of Acute Coronary Syndrome (free)