Critical Care & Emergencies (all articles)
Palliative Sedation: A Safety Net for the Relief of Refractory and Intolerable Symptoms at the End of Life
22 Jan, 2020 | 09:06h | UTC
Pain and Delirium: Mechanisms, Assessment, and Management
22 Jan, 2020 | 09:04h | UTCPain and delirium: mechanisms, assessment, and management – European Geriatric Management (free)
Review: Acute Myocardial Infarction in Young Individuals
21 Jan, 2020 | 03:01h | UTCAcute Myocardial Infarction in Young Individuals – Mayo Clinic Proceedings (free)
Study – Troponin Testing and Coronary Syndrome in Geriatric Patients with Nonspecific Complaints: Are We Overtesting?
21 Jan, 2020 | 02:58h | UTCCommentaries: Study questions routine troponin testing for ACS in geriatric patients with NSCs – Society for Academic Emergency Medicine (free) AND This Old Heart of Mine and Troponin Testing – The Skeptics Guide to EM (free)
[Abstract Only] Meta-Analysis: Thrombolysis for Acute Ischemic Stroke in the Unwitnessed or Extended Therapeutic Time Window
21 Jan, 2020 | 01:15h | UTCThrombolysis for acute ischemic stroke in the unwitnessed or extended therapeutic time window – Neurology (link to abstract – $ for full-text)
Source: EvidenceAlerts
The PEPTIC Randomized Clinical Trial: Similar Outcomes with Stress Ulcer Prophylaxis with Proton Pump Inhibitors vs. Histamine-2 Receptor Blockers Among ICU Patients Receiving Invasive Mechanical Ventilation
19 Jan, 2020 | 21:42h | UTCEditorial: Proton Pump Inhibitors vs Histamine-2 Receptor Blockers for Stress Ulcer Prophylaxis in Critically Ill Patients: Issues of Interpretability in Pragmatic Trials (free for a limited period)
Conference Presentation: Effect of Stress Ulcer Prophylaxis With PPIs vs H2RBs on Mortality in Ventilated ICU Patients (free)
Commentaries: JC: The PEPTIC study PPI vs H2RBs on the ICU – St Emlyn’s (free) AND Risks And Benefits Of Proton Pump Inhibitors To Prevent Gi Bleeds In Intensive Care Patients – MedicalResearch.com (free)
The VITAMINS Randomized Clinical Trial: Vitamin C, Hydrocortisone, and Thiamine Not beneficial for Patients with Sepsis
19 Jan, 2020 | 21:44h | UTCEffect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock: The VITAMINS Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Lack of Benefit of High-Dose Vitamin C, Thiamine, and Hydrocortisone Combination for Patients With Sepsis (free)
Conference Presentation: Effect of Vitamin C and Thiamine on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock (free)
Commentaries: JC: The Vitamins trial. Hydrocortisone, Vit C and Thiamine (Marik protocol – or not?) in sepsis – St Emlyn’s (free) AND Vitamin Treatment For Sepsis Fails In Large Trial – NPR (free) AND Metabolic Resuscitation: Was the answer inside us all along? – PulmCrit (free)
Position Statement on Endovascular Intervention for Trauma
19 Jan, 2020 | 20:57h | UTC
Chest Radiography in Adult Critical Care Unit: A Pictorial Review
19 Jan, 2020 | 20:47h | UTC
Respiratory Muscle Ultrasonography: Methodology, Basic and Advanced Principles and Clinical Applications in ICU and ED Patients
19 Jan, 2020 | 20:42h | UTC
What is New in Non-ventilated ICU-acquired Pneumonia?
19 Jan, 2020 | 20:41h | UTCWhat is new in non-ventilated ICU-acquired pneumonia? – Intensive Care Medicine (free)
Global, Regional, and National Sepsis Incidence and Mortality
17 Jan, 2020 | 09:44h | UTCCommentaries: A global accounting of sepsis – The Lancet (free) AND Sepsis associated with 1 in 5 deaths globally, double previous estimate – Institute for Health Metrics and Evaluation (free)
Related Commentary on Twitter
Presenting now #CCR20—First #GBDStudy estimates of #sepsis incident cases (49 million in 2017) & mortality (11 million in 2017) are twice that thought previously; highlighting need for greater prevention and treatment especially in sub-Saharan Africa @IHME https://t.co/vSwZVshhmt pic.twitter.com/nnPaQ5qmG8
— The Lancet (@TheLancet) January 16, 2020
Critical Care Management of Infectious Meningitis and Encephalitis
17 Jan, 2020 | 09:36h | UTCCritical care management of infectious meningitis and encephalitis – Intensive Care Medicine (free)
Acute Myocardial Infarction in Pregnancy: Current Diagnosis and Management Approaches
17 Jan, 2020 | 02:07h | UTC
Editorial: How I Search for a Sepsis Source
17 Jan, 2020 | 02:01h | UTCHow I search for a sepsis source – Critical Care (free)
Four Major Studies in Critical Care to be Presented at #CCR20 – PEPTIC, 65, & VITAMINS trials, plus the IHME Sepsis Study
16 Jan, 2020 | 08:59h | UTCFour major results to be presented at #CCR20 – PEPTIC, 65, & VITAMINS trials, plus the IHME Sepsis Study – More Info on the Critical Care Reviews Website
Commentary: Clinical trial results in critical care medicine to be unveiled at leading UK conference – EurekAlert (free)
1 – Thursday January 16th (09:00 to 10:30) – 65 Results Presentation Session – https://vimeo.com/383967830
See Study Protocol: Evaluating the clinical and cost-effectiveness of permissive hypotension in critically ill patients aged 65 years or over with vasodilatory hypotension: Protocol for the 65 randomised clinical trial – Journal of the Intensive Care Society (free)
2 – Thursday January 16th (16:35 to 17:40 – IHME Sepsis Study Results – https://vimeo.com/383968757
3 – Friday January 17th (09:00 to 10:30) – PEPTIC Trial Results Session – https://vimeo.com/383968980
See Study Protocol: A cluster randomised, crossover, registry-embedded clinical trial of proton pump inhibitors versus histamine-2 receptor blockers for ulcer prophylaxis therapy in the intensive care unit (PEPTIC study): study protocol. – Critical Care and Resuscitation (free PDF)
4 – Friday January 17th (11:00 to 12:30) – VITAMINS Trial Results – https://vimeo.com/383969217
Expert Statement: Clostridioides Difficile Infection in the Critically Ill
15 Jan, 2020 | 08:11h | UTCClostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement – Intensive Care Medicine (free for a limited period)
Related: Clostridioides Difficile: Diagnosis and Treatments (free BMJ review and guidelines on the subject)
Opinion – Should Bed Up Head Elevated be the New Standard Position for Rapid Sequence Intubation in the ED?
14 Jan, 2020 | 00:17h | UTCShould Bed Up Head Elevated (BUHE) be the New Standard Position for RSI in the ED? – RebelEM (free)
Original Study: Comparison of Macintosh Laryngoscopy in Bed-up-Head–Elevated Position With GlideScope Laryngoscopy: A Randomized, Controlled, Noninferiority Trial – Anesthesia & Analgesia (link to abstract – $ for full-text)
See also: Why Not Ramp All Intubations? New RCT Suggests We Should – JournalFeed (free)
Review: Brainstem Dysfunction in Critically Ill Patients
14 Jan, 2020 | 00:05h | UTCBrainstem dysfunction in critically ill patients – Critical Care (free)
Special Issue: Uncommon Severe Infections in the Intensive Care Unit
12 Jan, 2020 | 21:20h | UTCHomepage: Uncommon Severe Infections in the Intensive Care Unit – Clinical Microbiology and Infection (free articles)
– Improving care for the ICU patient with suspected infection: a multidisciplinary perspective
– Necrotizing skin and soft-tissue infections in the intensive care unit
– Management of infected pancreatic necrosis in the intensive care unit: a narrative review
– Mediastinitis in the intensive care unit patient: a narrative review
– When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit
Editorial – How I Set Up Positive End-Expiratory Pressure: Evidence- and Physiology-Based!
12 Jan, 2020 | 21:13h | UTCHow I set up positive end-expiratory pressure: evidence- and physiology-based! – Critical Care (free)
Mechanical Ventilation in Patients with Acute Ischemic Stroke: From Pathophysiology to Clinical Practice
12 Jan, 2020 | 21:12h | UTC
Observational Study: Implementation of a Hospital-Based Palliative Care Program Linked to Reduced Use of Intensive Care During Terminal Hospitalizations
12 Jan, 2020 | 20:55h | UTC
Viewpoint: High Quality Targeted Temperature Management (TTM) After Cardiac Arrest
12 Jan, 2020 | 20:58h | UTCHigh Quality Targeted Temperature Management (TTM) After Cardiac Arrest – Critical Care (free)
AHA Scientific Statement: Recognition and Initial Management of Fulminant Myocarditis
10 Jan, 2020 | 08:27h | UTCNews Release: Fast action and the right resources are key to treating fulminant myocarditis – American Heart Association (free)