Critical Care & Emergencies (all articles)
Invasive candidiasis in critical care: Challenges and future directions
1 Oct, 2020 | 09:00h | UTCInvasive candidiasis in critical care: challenges and future directions – Intensive Care Medicine
Commentary on Twitter
Invasive candidiasis: most common #ICU fungal infection ~40-55% mortality. Key challenges:
➡️ changing epidemiology/emergence of resistances
➡️ timely/appropriate therapy initiation/discontinuation
➡️ choosing/tailoring optimal antifungals#FOAMcc review https://t.co/tMPNcYfzwL pic.twitter.com/HvJKr0jX2o— Intensive Care Medicine (@yourICM) September 30, 2020
Systematic review: The effectiveness and cost‐effectiveness of hospital‐based specialist palliative care for adults with advanced illness and their caregivers
1 Oct, 2020 | 08:58h | UTC
Commentary on Twitter
Cochrane review on hospital-based specialist palliative care. Findings: Improved HR-QoL and patient satisfaction, reduced symptom burden and depression, and increased chances of patients dying in their preferred place. @SBajwah @cochranecollab https://t.co/wjhGp0gcbs
— Olaf Geerse (@OlafGeerse) September 30, 2020
New COVID-19 inpatient risk calculator estimates the probability of severe disease or death at hospital admission
30 Sep, 2020 | 09:51h | UTCCommentaries: COVID-19 ‘prediction model’ uses data that can help determine if patients’ conditions are likely to worsen – Johns Hopkins Medicine AND Prediction model incorporates more than 20 variables at hospital admission – Physician’s Weekly AND Patient Trajectories Among COVID-19 Hospitalized Patients – American College of Cardiology
Interactive Calculator: The COVID Inpatient Risk Calculator: CIRC
Commentary on Twitter
Lead authors Brian T. Garibaldi, MD, MEHP and Jacob Fiksel, PhD of @HopkinsMedicine developed the COVID-19 Inpatient Risk Calculator (CIRC) that uses patient data at admission to determine potential disease trajectory for #COVID19.
Link: https://t.co/i1e1ek7wO7. @Bedsidemedicine pic.twitter.com/wQLctHHYrn
— Annals of Int Med (@AnnalsofIM) September 22, 2020
Proposed clinical criteria for COVID-19-associated hyperinflammatory syndrome
30 Sep, 2020 | 09:50h | UTC
Commentary on Twitter
Defining and grading the clinical hyperinflammatory syndrome with #COVID19 and how this cytokine storm relates to outcomes https://t.co/6Ngp3OHZJx @TheLancetRheum @Intermountain pic.twitter.com/bDGwKpjOI4
— Eric Topol (@EricTopol) September 29, 2020
Intensive care unit acquired muscle weakness in COVID-19 patients
30 Sep, 2020 | 09:39h | UTCIntensive care unit acquired muscle weakness in COVID-19 patients – Intensive Care Medicine
Commentary on Twitter
#ICU acquired muscle weakness in #COVID19 frequently occurring in critically ills on prolonged sedation. Price to pay for rigorous protective MV? follow-up essential to offer tailored rehab, trying to reduce long-term impact on functional status. #ICUrehab https://t.co/anf0WE0W4w pic.twitter.com/MdnNzYuTN8
— Intensive Care Medicine (@yourICM) September 28, 2020
Editorial – Stress ulcer prophylaxis: Is mortality a useful endpoint?
30 Sep, 2020 | 09:31h | UTCStress ulcer prophylaxis: Is mortality a useful endpoint? – Intensive Care Medicine
Commentary on Twitter
Stress ulcer prophylaxis: restrict to highest GI bleeding risk #ICU pts; still uncertainties on harmful effects (ie PK interactions?). Early EN, effective if low-risk + reducing underfeeding, to be encouraged. https://t.co/2EOsefikFc
Referring Wang et al https://t.co/MXnfHYyoJ4 pic.twitter.com/Xz8wmTzn62
— Intensive Care Medicine (@yourICM) September 29, 2020
IDSA updated guidelines on the treatment of patients with COVID-19
28 Sep, 2020 | 01:40h | UTC
Commentary on Twitter
.@IDSAInfo has updated its #COVID19 treatment guidelines:
*Don't give #tocilizumab
*Give #dexamethasone but not if room air oxygen saturation is > 94%https://t.co/66nwQQZgsz pic.twitter.com/PQNAaFBZS4— Mike Stevens (@Dr_Mike_Stevens) September 26, 2020
ECMO in Covid-19: An international cohort
28 Sep, 2020 | 01:33h | UTC
Gastrointestinal complications in critically ill patients with and without COVID-19
25 Sep, 2020 | 02:44h | UTCGastrointestinal Complications in Critically Ill Patients With and Without COVID-19 – JAMA
Commentary on Twitter
https://twitter.com/LMaurerMD/status/1309185925692481536
Small randomized trial evaluated intravenous methylprednisolone pulse as a treatment for hospitalized severe COVID-19 patients
25 Sep, 2020 | 02:41h | UTC
Understanding necrotizing soft tissue infections in the intensive care unit
25 Sep, 2020 | 02:31h | UTC
Commentary on Twitter
Necrotizing soft tissue infections in #ICU, focus on optimizing interventions most likely to impact outcome:
➡️ keep high index of suspicion vs misdiagnosis/delays in starting treatment
➡️ coordinate urgent approach: early debridement + broad-spectrum ABThttps://t.co/NpkxYFHbGl pic.twitter.com/8LDQuOGobI— Intensive Care Medicine (@yourICM) September 22, 2020
JAMA Network Series: Medical Specialties and the COVID-19 Pandemic
24 Sep, 2020 | 09:45h | UTCEditorial: The COVID-19 Pandemic and the JAMA Network
See articles:
- Cardiology and COVID-19
- Dermatology and COVID-19
- Internal Medicine and COVID-19
- Nephrology and COVID-19
- Neurology and COVID-19
- Oncology and COVID-19
- Ophthalmology and COVID-19
- Otolaryngology–Head and Neck Surgery and COVID-19
- Pediatrics and COVID-19
- Psychiatry and COVID-19
- Surgery and COVID-19
- JAMA Network Open and COVID-19
- JAMA Health Forum and COVID-19
Association of red blood cell distribution width with mortality risk in hospitalized adults with SARS-CoV-2 infection
24 Sep, 2020 | 09:32h | UTCCommentary: Simple blood test can predict severity of COVID-19 for some patients – University of Texas Health Science Center at Houston AND Routine blood test may identify patients at risk for severe COVID-19 – UPI
Commentary on Twitter
Death in #COVID19: JAMA Open
In lots of dzs RDW >14.5% robustly risk stratifies pts w/in illness. True in #COVID! Mortality w/ nl RDW 11% vs. 31% with high RDW (9% ⬆️ risk per 0.5% increase in RDW). BEST predictor next to Age!https://t.co/aZJ3p488cN#medtwitter #tipsfornewdocs pic.twitter.com/967g2HElYH— WesElyMD (@WesElyMD) September 23, 2020
COVID-19 can affect the heart
24 Sep, 2020 | 09:30h | UTCCOVID-19 can affect the heart – Science
Commentary on Twitter
"These complications, which at times are the only features of #COVID19 clinical presentation, have occurred even in cases with mild symptoms and in people who did not experience any symptoms" https://t.co/q42cY3ujV4
a 🧵to explain 1/— Eric Topol (@EricTopol) September 24, 2020
Things we do for no reason: Routine correction of elevated INR and thrombocytopenia prior to paracentesis in patients with cirrhosis
24 Sep, 2020 | 09:17h | UTCSee collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine
Things we do for no reason: Routine coverage of anaerobes in aspiration pneumonia
24 Sep, 2020 | 09:17h | UTCSee collection: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine
[Preprint] Randomized trial: Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers
23 Sep, 2020 | 14:17h | UTC
Commentary on Twitter
🔥 #Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial 🔥
-1st RCT on HCQ as PrEP
-1483 HCW randomized to HCQ 1x or 2x weekly or placebo
-No difference in development of confirmed or probable COVID19 https://t.co/Gn1otqKhrW pic.twitter.com/3r0HB56h9y
— Ilan Schwartz is on🦋 (@GermHunterMD) September 21, 2020
COVID-19 clinical trials: Learning from exceptions in the research chaos
23 Sep, 2020 | 14:50h | UTCCOVID-19 clinical trials: learning from exceptions in the research chaos – Nature
Commentary on Twitter
Our analysis on #COVID clinical trials on Nature Medicine. Only big randomised trials can answer rapidly & reliably. Megatrials need support from regulators, funders, health services, docs. Pre-existing trial networks helpful. Collaboration key to success. https://t.co/YlalAEMR9r pic.twitter.com/wElfXfXdol
— Kari Tikkinen (@KariTikkinen) September 22, 2020
Cardiac arrhythmias in critically ill patients with COVID-19: A brief review
22 Sep, 2020 | 09:59h | UTC
Catheter-associated urinary tract infections in adults: diagnosis, treatment, and prevention
23 Sep, 2020 | 14:35h | UTCCatheter-Associated Urinary Tract Infections in Adults: Diagnosis, Treatment, and Prevention – Journal of Hospital Medicine (free for a limited period)
The core lesson of the COVID-19 heart debate
22 Sep, 2020 | 10:00h | UTCThe Core Lesson of the COVID-19 Heart Debate – The Atlantic
Commentary on Twitter
https://twitter.com/ChecchiaPaul/status/1308065655099478018
Hospital COVID-19 risk lowest among intensive care staff
22 Sep, 2020 | 09:53h | UTCHospital COVID-19 risk lowest among intensive care staff – MedicalXpress
Original Study: SARS-CoV-2 seroprevalence and asymptomatic viral carriage in healthcare workers: a cross-sectional study – Thorax
Commentary on Twitter
HOT OF THE PRESS@ThoraxBMJ#Covid19UK#NHS hospital staff
Asymptomatic viral carriage
2.4%Seroprevalence
▶️ Housekeeping 34.5%
▶️ Acute medicine 33.3%
▶️ General internal medicine 30.3%
▶️ Intensive care 14.8%#protectNHSstaff#protectNHSpatientshttps://t.co/iqBKl3qLYD— Prof. Nicholas Hart (@NickHartGSTT) September 12, 2020
Ensuring adequate palliative and hospice care during COVID-19 surges
22 Sep, 2020 | 09:57h | UTCEnsuring Adequate Palliative and Hospice Care During COVID-19 Surges – JAMA
Commentary on Twitter
An ethical approach to #pandemic surge planning requires providing for patients seeking symptom relief & comfort at the end of life. Not to do so undermines patient, family trust, emotional health, and core values of society https://t.co/P0LeYuZwzt @MatthewWynia @CUPallCare
— JAMA (@JAMA_current) September 22, 2020
Editorial: How severe COVID-19 infection is changing ARDS management
22 Sep, 2020 | 09:37h | UTCHow severe COVID-19 infection is changing ARDS management – Intensive Care Medicine
Concise review: Management of acute ischemic stroke
22 Sep, 2020 | 09:26h | UTCManagement of Acute Ischemic Stroke – Critical Care Medicine


