Critical Care & Emergencies (all articles)
[News release – not published yet] Eli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19
9 Oct, 2020 | 09:09h | UTCEli Lilly says its monoclonal antibody cocktail is effective in treating Covid-19 – STAT
Study: Neurologic manifestations occur in most hospitalized Covid‐19 patients
9 Oct, 2020 | 09:11h | UTCCommentaries: COVID-19 neurological symptoms emerge in most hospitalized patients, study says AND Many hospitalized COVID-19 patients exhibit neurological symptoms, study finds – News Medical AND More than 80% of people hospitalized for COVID-19 suffer neurological symptoms, from confusion to altered brain function – Business Insider
Non-invasive positive pressure ventilation in patients with COVID-19
9 Oct, 2020 | 08:58h | UTCNon-Invasive Positive Pressure Ventilation in Patients With COVID-19 – Mayo Clinic Proceedings
Systematic review: Not enough evidence to recommend vena caval filters for the prevention of pulmonary embolism
9 Oct, 2020 | 08:52h | UTCVena caval filters for the prevention of pulmonary embolism – Cochrane Library
Summary: Vena caval filters for the prevention of pulmonary embolism – Cochrane Library
Editorial: The ten reasons why corticosteroid therapy reduces mortality in severe COVID-19
8 Oct, 2020 | 09:15h | UTC
ATS/ERS Updated guidance on the management of COVID-19
8 Oct, 2020 | 09:16h | UTC
COVID-19 and the kidney
8 Oct, 2020 | 09:02h | UTCCOVID-19 and the kidney – Cleveland Clinic Journal of Medicine
Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19
7 Oct, 2020 | 08:50h | UTCCommentaries: Study: HIV drug of no benefit to hospitalized COVID patients – CIDRAP AND Antiviral monotherapy for hospitalised patients with COVID-19 is not enough – The Lancet AND
Commentary on Twitter
NEW—Lopinavir-ritonavir is not an effective treatment for patients hospitalised with #COVID19: finding from RECOVERY, randomised, controlled, open-label, platform trial https://t.co/RpiUAvWF1I pic.twitter.com/uI3yiQbEgK
— The Lancet (@TheLancet) October 6, 2020
ACEP Clinical Policy: Critical issues related to opioids in adult patients presenting to the emergency department
8 Oct, 2020 | 08:53h | UTCCommentary: ACEP Opioid Policy Statement – Journal Feed
ACP Guidance: Should Remdesivir be used for the treatment of patients with COVID-19?
7 Oct, 2020 | 09:21h | UTCSystematic review: Remdesivir for Adults With COVID-19: A Living Systematic Review for an American College of Physicians Practice Points – Annals of Internal Medicine
Covid-19: Risk of death more than doubled in people who also had flu, English data show
7 Oct, 2020 | 09:11h | UTCCovid-19: Risk of death more than doubled in people who also had flu, English data show – The BMJ
Original study (preprint): Interactions between SARS-CoV-2 and Influenza and the impact of coinfection on disease severity: A test negative design – medRxiv
Commentary on Twitter
People infected with both flu and SARS-CoV-2 are more than twice as likely to die as someone with the new coronavirus alone, emerging evidence analysed by @PHE_uk has found. The data has been published as a preprint on medRxivhttps://t.co/3Qv3gxGRXB
— The BMJ (@bmj_latest) September 23, 2020
Randomized trial: Tranexamic acid during prehospital transport in patients at risk for hemorrhage after injury
7 Oct, 2020 | 09:04h | UTCCommentaries: Prehospital Tranexamic Acid: STAAMP of Approval or Return to Sender? – JAMA Surgery AND Trial examines prehospital administration of blood-clotting agent in severely injured trauma patients – News Medical
Commentary on Twitter
TXA as an adjunct to prehospital #injury management seems to improve #outcome but only in specific subgroups. A nicely done multicenter trial that raises more questions to be answered. @SCCM @JAMASurgery https://t.co/rTQz8qJO0o
— Lauren R. Sorce, PhD, RN, CPNP-AC/PC, FAAN, FCCM (@SCCMPresident) October 5, 2020
Systematic Review: Thoracic imaging tests for the diagnosis of COVID‐19
7 Oct, 2020 | 09:07h | UTCThoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library
Commentaries: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library AND Featured Review: Thoracic imaging tests for the diagnosis of COVID-19 – Cochrane Library
Systematic review: Complications of cricothyroidotomy versus tracheostomy in emergency surgical airway management
7 Oct, 2020 | 08:52h | UTC
Long-term health consequences of COVID-19
6 Oct, 2020 | 00:58h | UTCLong-term Health Consequences of COVID-19 – JAMA
Commentary on Twitter
Persistent post-COVID symptoms could be the from direct tissue invasion by the virus, profound inflammation & cytokine storm, related immune system damage, hypercoagulable state, or some combination https://t.co/G8tI9U3TaL @CarlosdelRio7 lfcollins_md @PreetiNMalani
— JAMA (@JAMA_current) October 5, 2020
Meta-analysis: Risk of venous thromboembolism in patients with COVID‐19
6 Oct, 2020 | 00:54h | UTC
Commentaries on Twitter
In a new #RPTH paper, researchers performed a meta-analysis of #VTE risk in #COVID19 patients: 22.7% prevalence in ICU vs. 7.9% in non-ICU patients. Other subgroup analyses reveal heterogeneity and interesting trends…@Cihan_Ay_MD @FlorianMoik NEW: https://t.co/24IWOm5qTe pic.twitter.com/HjnSYq9YKz
— RPTH (@RPTHjournal) September 30, 2020
Meta-analysis of #clotting events in 66 studies including 28173 patients with #COVID19. High #VTE & #PE prevalence in ICU patients indicates a need for thromboprophylaxis research! Read the results at #RPTH by @Cihan_Ay_MD @FlorianMoik https://t.co/24IWOlNPuE @thrombosisday pic.twitter.com/V4Pn2ssBH3
— RPTH (@RPTHjournal) October 5, 2020
What we have found was a trend of decreased VTE rates over time. Earlier studies reported slightly higher VTE rates than more recent ones. What could be the reason? Experience dealing with COVID19 and improved preventive strategies? https://t.co/YDjRyvNmK6 https://t.co/y3Uj5x3QRI pic.twitter.com/0HcFQvMJB8
— Cihan Ay (@Cihan_Ay_MD) September 26, 2020
Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection
4 Oct, 2020 | 23:36h | UTCCommentary: Mysterious inflammatory syndrome tied to COVID-19 strikes adults as well as kids – Live Science
Commentary on Twitter
A new @CDCMMWR finds that adults who had #COVID19 can develop a condition similar to multisystem inflammatory syndrome in children and have severe outcomes including requiring intensive care. Learn more: https://t.co/dU1tS85Sj3. pic.twitter.com/RitCzJsLTL
— CDC (@CDCgov) October 2, 2020
Perspective: What we know about vitamin D and Covid-19 (spoiler: not much)
4 Oct, 2020 | 23:28h | UTCWhat We Know About Vitamin D and Covid-19 – Medium
Editorial: COVID ARDS is not different from ARDS of other causes. Patients should be managed according to the evidence-based recommendations for non COVID related ARDS.
4 Oct, 2020 | 23:23h | UTC
Commentary on Twitter
#COVID19 #ARDS? after careful bedside physiological assessment, we may state #SARSCoV2 pts may be managed according to evidence-based recommendations for non COVID related ARDS@audreydejongMD @oriolrocag https://t.co/71TqeTJXMW
On @cafeoranestesia et al https://t.co/FZS2oGm30D pic.twitter.com/HJQ4FLCuL2
— Intensive Care Medicine (@yourICM) October 3, 2020
Evaluation of oxygenation in 129 proning sessions in 34 mechanically ventilated COVID-19 patients
4 Oct, 2020 | 23:24h | UTC
ASH 2020 guidelines for the management of deep vein thrombosis and pulmonary embolism
4 Oct, 2020 | 23:12h | UTC
Cohort study: In-hospital cardiac arrest in critically ill patients with Covid-19
2 Oct, 2020 | 09:24h | UTCCommentary: Cardiac arrest, poor survival rates common in sickest patients with COVID-19 – University of Michigan
Related Study: Clinical Outcomes of In-Hospital Cardiac Arrest in COVID-19 – JAMA Internal Medicine
Commentaries on Twitter
Cardiac arrest with severe #COVID19, in-hospital:
relatively common, very poor outcome, especially w/ ⬆️age
Two series:
701 patients (14%)https://t.co/Pu0V15lemL @bmj_latest @salimhayek @umichmedicine @MHealthLab
60 patients (5%)https://t.co/Exwk68VXgg @JAMAInternalMed pic.twitter.com/9cwS0HlNxz— Eric Topol (@EricTopol) October 2, 2020
Cardiac arrest is common in critically ill patients with #COVID19 and is associated with poor survival, particularly among patients aged 80 or older, finds new research @salimhayek
https://t.co/O2Z2K3TAeT— The BMJ (@bmj_latest) October 1, 2020
Randomized trial: Hydroxychloroquine vs. placebo for pre-exposure SARS-CoV-2 prophylaxis among health care workers
1 Oct, 2020 | 09:17h | UTCCommentary: Hydroxychloroquine didn’t prevent COVID-19 among health care workers in new study – CNN
Commentary on Twitter
#Hydroxychloroquine taken daily by hospital-based health care providers over 8 weeks did not prevent #SARSCoV2 infection, in a double-blind randomized placebo-controlled trial performed at 2 University of Pennsylvania hospitals https://t.co/7XHn6uBh4Z
— JAMA Internal Medicine (@JAMAInternalMed) September 30, 2020
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline
1 Oct, 2020 | 09:15h | UTC
Commentary on Twitter
🔥Just published🔥@CMIJournal
Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline by the Dutch Working Party on Antibiotic Policy. #IDTwitter #COVID19 https://t.co/7cfZtS6Duv pic.twitter.com/Kz7CPMNLmh— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) September 30, 2020
Keeping best practices in critical care during COVID-19
1 Oct, 2020 | 09:08h | UTCKeeping Best Practices in Critical Care During COVID-19 – ICU Management & Practice
Commentary on Twitter
COVID-19 poses several challenges and has made it difficult to measure ICU performance.
Read the article 'Keeping Best Practices in Critical Care During COVID-19' by @f_g_zampieri 👉https://t.co/kvwlGSLBav#Covid19 #ICU #patientoutcome #FOAMcc #FOAMed pic.twitter.com/2YOhOnidxZ
— ICU Management (@ICU_Management) September 28, 2020