Emergency Medicine

M-A: Diagnostic performance of CO-RADS for Covid-19.

8 Apr, 2022 | 10:31h | UTC

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Related: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology

 

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Stroke: advances in treatment offer hope for patients.

8 Apr, 2022 | 10:23h | UTC

Stroke: advances in treatment offer hope for patients – Evidently Cochrane

 

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Study Commentary | Immediate versus delayed cardiac catheterization in post-arrest patients without ST elevation myocardial infarction: is survivorship bias an important influence?

8 Apr, 2022 | 10:11h | UTC

Immediate Versus Delayed Cardiac Catheterization in Post-Arrest Patients Without ST Elevation Myocardial Infarction: Is Survivorship Bias an Important Influence? – Annals of Emergency Medicine

Original Study: #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

 

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Study Commentary | Back to BaSICS (study that compared balanced solution vs. 0.9% saline solution in critically ill patients).

8 Apr, 2022 | 10:09h | UTC

Back to BaSICS – Annals of Emergency Medicine

Original Studies:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Related:

Perspective: The ongoing saga of normal saline vs. balanced fluids.

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

 

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Study Commentary | To Bougie or not to Bougie: Bougie vs. Stylet for first-pass intubation success.

8 Apr, 2022 | 10:07h | UTC

To Bougie or Not to Bougie: Bougie versus Stylet for First-Pass Intubation Success – Annals of Emergency Medicine

Original Study: RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.

 

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Brief Review: How to do lung ultrasound.

8 Apr, 2022 | 09:52h | UTC

How to do lung ultrasound – European Heart Journal – Cardiovascular Imaging

 

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Study finds increased risk of pulmonary embolism up to 110 days after COVID-19.

7 Apr, 2022 | 10:06h | UTC

Risks of deep vein thrombosis, pulmonary embolism, and bleeding after covid-19: nationwide self-controlled cases series and matched cohort study – The BMJ

News Release: Study finds increased risk of serious blood clots up to six months after COVID-19 – BMJ

Editorial: Thromboembolism and bleeding after covid-19

Commentary: Covid: Blood clot risk higher for six months after having virus – BBC

 

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Pragmatic RCT: In outpatients with Covid-19, the addition of pulse oximetry for monitoring did not improve outcomes compared to subjective assessments of dyspnea alone.

7 Apr, 2022 | 09:58h | UTC

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

 

Commentary on Twitter

A potential practice changer by @kit_delgadoMD et al in NEJM today.

At-home pulse oximeters did NOT improve outcomes.

Important to focus on things that help.

If these devices don't help, then we shouldn't routinely advise them.

Super interesting work.https://t.co/VDDyRLw7ba

— Jeremy Faust MD MS (ER physician) (@jeremyfaust) April 6, 2022

 

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RCT: Among patients with complicated urinary tract infection, oral Tebipenem Pivoxil Hydrobromide was noninferior to intravenous Ertapenem and showed a similar safety profile.

7 Apr, 2022 | 09:53h | UTC

Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

For complicated UTI or acute pyelonephritis, oral tebipenem pivoxil hydrobromide noninferior to IV ertapenem and has a similar safety profile. https://t.co/FRDMQOD0Pn pic.twitter.com/GFQz7SlciX

— NEJM (@NEJM) April 6, 2022

 

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RCT: In patients undergoing intraarterial treatment for stroke, functional outcomes after 3 months were similar with general anesthesia vs. sedation.

7 Apr, 2022 | 08:00h | UTC

General Anesthesia versus Sedation, Both with Hemodynamic Control, during Intraarterial Treatment for Stroke: The GASS Randomized Trial – Anesthesia

 

Commentary on Twitter

Previous speculations have considered the relationship between anesthetic strategy and patient outcomes. Now, new research suggests general #anesthesia and #sedation produce comparable outcomes after endovascular treatment for stroke. https://t.co/ggLRO8Or3W pic.twitter.com/dLLGA4Vmgk

— Anesthesiology journal (@_Anesthesiology) March 24, 2022

 

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Major burns: part 2. Anesthesia, intensive care and pain management.

7 Apr, 2022 | 07:59h | UTC

Major burns: part 2. Anaesthesia, intensive care and pain management – BJA Education

See also: Major burns: Part 1. Epidemiology, pathophysiology and initial management.

 

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RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

6 Apr, 2022 | 10:47h | UTC

Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage: two randomized phase 3 trials in Japanese patients – Journal of Neurosurgery

 

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Craniocervical artery dissections: a concise review for clinicians.

6 Apr, 2022 | 10:06h | UTC

Craniocervical Artery Dissections: A Concise Review for Clinicians – Mayo Clinic Proceedings

 

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Review: Fulminant myocarditis in adults.

6 Apr, 2022 | 09:55h | UTC

Fulminant myocarditis in adults: a narrative review – Journal of Geriatric Cardiology

 

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Systematic Review: Videolaryngoscopy vs. direct laryngoscopy for adults undergoing tracheal intubation.

5 Apr, 2022 | 09:52h | UTC

Videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation – Cochrane Library

 

Commentary from the author on Twitter (thread – click for more)

1/ We just published our full @Cochrane_ACE systematic review and meta-analysis of videolaryngoscopy versus direct laryngoscopy for adults undergoing tracheal intubation.

The full review is here, but first – some of our key takeaways ?https://t.co/HxzXhF83ZB

— Jan Hansel (@VirtueOfNothing) April 4, 2022

 

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Consensus Statement: Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis.

5 Apr, 2022 | 09:54h | UTC

Definition, diagnosis, and management of COVID-19-associated pulmonary mucormycosis: Delphi consensus statement from the Fungal Infection Study Forum and Academy of Pulmonary Sciences, India – The Lancet Infectious Diseases

 

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Seminar: Acute coronary syndromes.

5 Apr, 2022 | 09:48h | UTC

Acute coronary syndromes – The Lancet (free for a limited period)

 

Commentary on Twitter

Despite substantial progress in the diagnosis & treatment of acute coronary syndromes, cardiovascular disease remains the leading cause of death globally.

This new Seminar provides a clinical overview & describes key scientific advances. https://t.co/jRHmVWmVX0

— The Lancet (@TheLancet) April 2, 2022

 

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Review: The intensivist’s perspective of shock, volume management, and hemodynamic monitoring.

5 Apr, 2022 | 08:20h | UTC

The Intensivist’s Perspective of Shock, Volume Management, and Hemodynamic Monitoring – Clinical Journal of the American Society of Nephrology

 

Commentary on Twitter

Fluid therapy is a leading management strategy in patients with hypovolemic & distributive shock. This Critical Care Nephrology and Acute Kidney Injury article reviews hemodynamic monitoring approaches to assessing fluid responsiveness & fluid tolerance https://t.co/7Rh0DGtgRM pic.twitter.com/t8ZNXJTszn

— CJASN (@CJASN) April 4, 2022

 

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Podcast: Acute pancreatitis pearls.

5 Apr, 2022 | 08:26h | UTC

#327 Acute Pancreatitis – The Curbsiders

 

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Pericardial effusion and cardiac tamponade: pearls and pitfalls.

5 Apr, 2022 | 08:13h | UTC

Pericardial Effusion and Cardiac Tamponade: Pearls and Pitfalls – emDocs

 

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State of the Art Review: The heart brain team and patient-centered management of ischemic stroke.

1 Apr, 2022 | 09:53h | UTC

The Heart Brain Team and Patient-Centered Management of Ischemic Stroke – JACC: Advances

 

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Development of a consensus-based definition of Focused Assessment with Sonography for Trauma (FAST) in children.

1 Apr, 2022 | 08:35h | UTC

Development of a Consensus-Based Definition of Focused Assessment With Sonography for Trauma in Children – JAMA Network Open

Commentaries:

New FAST Definitions May Improve Trauma Assessment of Children – Medscape (free registration required)

Ultrasonographic views, landmarks, and patient-specific factors to consider in a consensus-based definition of the Focused Assessment With Sonography for Trauma in children with abdominal injury – Physician’s Weekly

 

Commentary on Twitter

Qualitative study describes the development of an expert definition for high-quality & accurate pediatric Focused Assessment with Sonography for Trauma (FAST), including recommended views, landmarks & imaging quality. @aaronkornblith @nkpluso @pocusnetwork https://t.co/4CTvGp2Rqs

— JAMA Network Open (@JAMANetworkOpen) March 18, 2022

 

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RCT: Early treatment with ivermectin does not improve outcomes in patients with Covid-19.

31 Mar, 2022 | 08:41h | UTC

Effect of Early Treatment with Ivermectin among Patients with Covid-19- New England Journal of Medicine

Commentary: Ivermectin does not prevent COVID-19 hospitalization, a new study says – NPR

 

Commentary on Twitter

Ivermectin: the largest randomized, double-blind trial yet conducted, with early treatment, indicates there is no difference compared with placebo. It doesn't work. Period. https://t.co/wiFygjRgkk
just published @NEJM pic.twitter.com/uZ0mMZnO0E

— Eric Topol (@EricTopol) March 30, 2022

 

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RCT: Early outpatient treatment with convalescent plasma reduces the risk of hospitalization in patients with Covid-19.

31 Mar, 2022 | 08:39h | UTC

Early Outpatient Treatment for Covid-19 with Convalescent Plasma – New England Journal of Medicine

Commentaries:

Study finds convalescent plasma can be effective early COVID-19 therapy – Johns Hopkins University School of Medicine

Early Use of High-Titer Plasma Reduced COVID Hospitalizations— Randomized trial that influenced indication shows benefits in a mostly unvaccinated population – MedPage Today (free registration required)

 

Commentary on Twitter

Fewer recipients of convalescent plasma had progression of Covid-19–associated illness leading to hospitalization. https://t.co/joa9ajpAcd pic.twitter.com/mHTnEHYN2O

— NEJM (@NEJM) March 30, 2022

 

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Review | Advanced heart failure: guideline-directed medical therapy, diuretics, inotropes, and palliative care.

31 Mar, 2022 | 08:09h | UTC

Advanced heart failure: guideline-directed medical therapy, diuretics, inotropes, and palliative care – ESC Heart Failure

 

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