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Emergency Medicine

Practice Pointer: Making decisions about radiological imaging in pregnancy.

26 Apr, 2022 | 08:44h | UTC

Making decisions about radiological imaging in pregnancy – The BMJ

 

Yes, relapses after Paxlovid happen — now what?

26 Apr, 2022 | 08:18h | UTC

Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations

 

Commentary on Twitter

 

Cluster RCT: Supraglottic airway device vs. tracheal intubation in the initial airway management of out-of-hospital cardiac arrest.

26 Apr, 2022 | 08:12h | UTC

Supraglottic airway device versus tracheal intubation in the initial airway management of out-of-hospital cardiac arrest: the AIRWAYS-2 cluster RCT – Health Technology Assessment

Related Study: Effect of Placement of a Supraglottic Airway Device vs Endotracheal Intubation on Return of Spontaneous Circulation in Adults With Out-of-Hospital Cardiac Arrest in Taipei, Taiwan: A Cluster Randomized Clinical Trial – JAMA Network Open

 

Gout in the ED: Pearls and pitfalls.

26 Apr, 2022 | 07:37h | UTC

Gout in the ED: Pearls and Pitfalls – emDocs

 

WHO recommends highly successful COVID-19 therapy (nirmatrelvir-ritonavir) and calls for wide geographical distribution and transparency from originator.

22 Apr, 2022 | 09:36h | UTC

WHO recommends highly successful COVID-19 therapy and calls for wide geographical distribution and transparency from originator – World Health Organization

See also:

A living WHO guideline on drugs for covid-19 – The BMJ

Therapeutics and COVID-19: living guideline – World Health Organization

Related:

Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel

 

Commentary on Twitter

 

Expert Guidance: Strategies to prevent central line-associated bloodstream infections in acute-care hospitals.

20 Apr, 2022 | 10:13h | UTC

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

 

Commentary on Twitter

Article under a http://creativecommons.org/licenses/by/4.0/ license

 

AAOS Guideline: Prevention of surgical site infections after major extremity trauma.

19 Apr, 2022 | 02:35h | UTC

Prevention of Surgical Site Infections After Major Extremity Trauma: Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Evidence Review: Prevention of Surgical Site Infection After Extremity Trauma (2022)

 

Acute hepatitis in ED setting: etiologies, evaluation, and management.

19 Apr, 2022 | 01:54h | UTC

Acute Hepatitis in ED Setting: Etiologies, Evaluation, and Management – emDocs

 

Prospective validation of a rapid host gene expression test to discriminate bacterial from viral respiratory infection.

18 Apr, 2022 | 09:58h | UTC

Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection – JAMA Network Open

 

Commentary on Twitter

 

RCT: Comparison of intranasal vs. intramuscular naloxone in opioid overdoses managed by ambulance staff.

14 Apr, 2022 | 08:23h | UTC

Comparison of intranasal and intramuscular naloxone in opioid overdoses managed by ambulance staff: a double-dummy, randomised, controlled trial – Addiction

Commentary: Breathing restored within 10 minutes for 80% of overdose patients using nasal spray – Norwegian University of Science and Technology

 

Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis.

13 Apr, 2022 | 10:15h | UTC

Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis – Health Technology Assessment

 

Empyema: ED presentation, evaluation, and management.

12 Apr, 2022 | 08:44h | UTC

Empyema: ED Presentation, Evaluation, and Management – emDocs

 

Editorial | Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation.

12 Apr, 2022 | 08:49h | UTC

Who? When? Where? How? Still the alpha and omega of extracorporeal cardiopulmonary resuscitation – European Heart Journal. Acute Cardiovascular Care

Original Study: The association between time to extracorporeal cardiopulmonary resuscitation and outcome in patients with out-of-hospital cardiac arrest – European Heart Journal. Acute Cardiovascular Care (link to abstract – $ for full-text)

Related:

RCT: In patients with refractory out-of-hospital cardiac arrest, a strategy of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment did not significantly improve survival with a favorable neurological outcome (OR 1.63; 95% CI 0.93 to 2.85; P = .09).

Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications.

Guidelines for extracorporeal cardiopulmonary resuscitation in children and adults

 

Commentary on Twitter

 

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management.

11 Apr, 2022 | 02:00h | UTC

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine

 

Review: Atrial fibrillation.

11 Apr, 2022 | 01:57h | UTC

Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Atrial fibrillation – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 

Clinical care of severe acute respiratory infections – Tool kit (COVID-19 adaptation, update 2022).

11 Apr, 2022 | 01:45h | UTC

Clinical care of severe acute respiratory infections – Tool kit – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

M-A: Prophylactic therapies for morbidity and mortality after aneurysmal subarachnoid hemorrhage.

11 Apr, 2022 | 00:52h | UTC

Prophylactic Therapies for Morbidity and Mortality After Aneurysmal Subarachnoid Hemorrhage: A Systematic Review and Network Meta-Analysis of Randomized Trials – Stroke (link to abstract – $ for full-text)

Related: RCT: Effects of clazosentan on cerebral vasospasm–related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage.

 

Commentary on Twitter

 

M-A: Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome.

11 Apr, 2022 | 00:48h | UTC

Prehospital risk assessment in patients suspected of non-ST-segment elevation acute coronary syndrome: a systematic review and meta-analysis – BMJ Open

 

Commentary on Twitter

 

State of the Art Review: Prognostication and shared decision making in neurocritical care.

8 Apr, 2022 | 10:53h | UTC

Prognostication and shared decision making in neurocritical care – The BMJ

 

Commentary on Twitter

 

M-A: Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia.

8 Apr, 2022 | 10:50h | UTC

Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases

Related:

Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US.

Review: Vaccine-induced immune thrombotic thrombocytopenia.

Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)

 

M-A: Diagnostic performance of CO-RADS for Covid-19.

8 Apr, 2022 | 10:31h | UTC

Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology

Related: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology

 

Stroke: advances in treatment offer hope for patients.

8 Apr, 2022 | 10:23h | UTC

Stroke: advances in treatment offer hope for patients – Evidently Cochrane

 

Study Commentary | Immediate versus delayed cardiac catheterization in post-arrest patients without ST elevation myocardial infarction: is survivorship bias an important influence?

8 Apr, 2022 | 10:11h | UTC

Immediate Versus Delayed Cardiac Catheterization in Post-Arrest Patients Without ST Elevation Myocardial Infarction: Is Survivorship Bias an Important Influence? – Annals of Emergency Medicine

Original Study: #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

 

Study Commentary | Back to BaSICS (study that compared balanced solution vs. 0.9% saline solution in critically ill patients).

8 Apr, 2022 | 10:09h | UTC

Back to BaSICS – Annals of Emergency Medicine

Original Studies:

BaSICS RCT: Among critically ill patients requiring fluid therapy, treatment with a balanced solution did not lead to reduced mortality compared to a 0.9% saline solution.

BaSICS RCT: Among critically ill patients requiring fluid therapy, there was no difference in mortality with slower (333 mL/h) vs. faster (999 mL/h) intravenous fluid bolus rates.

Related:

Perspective: The ongoing saga of normal saline vs. balanced fluids.

RCT: In critically ill adults, using a balanced multielectrolyte solution did not lower the risk of death or acute kidney injury compared to standard saline.

Balanced Crystalloids versus Saline in Critically Ill Adults — A Systematic Review with Meta-Analysis – NEJM Evidence

Cochrane Review: Buffered Solutions Do Not Improve Mortality in Critically Ill Adults and Children Compared to 0,9% Saline

 

Study Commentary | To Bougie or not to Bougie: Bougie vs. Stylet for first-pass intubation success.

8 Apr, 2022 | 10:07h | UTC

To Bougie or Not to Bougie: Bougie versus Stylet for First-Pass Intubation Success – Annals of Emergency Medicine

Original Study: RCT: In critically ill adults undergoing tracheal intubation, use of a bougie did not significantly increase the incidence of successful first attempt intubation vs. with use of an endotracheal tube with stylet.

 

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